Developmentally regulated expression and activity of 17α- hydroxylase/C-17,20-lyase cytochrome P450 in rat liver

Endocrinology

Volumn 138, Issue 8, 1997, Pages 3166-3174

  Vianello, Silvia ^a   Waterman, Michael R ^b   Dalla Valle, Luisa ^a   Colombo, Lorenzo ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN; CYTOCHROME P450; GESTAGEN; STEROID 17,20 LYASE; STEROID 17ALPHA MONOOXYGENASE;

ANIMAL TISSUE; AROMATIZATION; ARTICLE; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME LOCALIZATION; FEMALE; GRANULOSA CELL; LIVER MICROSOME; MALE; NONHUMAN; PERINATAL PERIOD; PRIORITY JOURNAL; RAT; SERTOLI CELL; STEROIDOGENESIS;

EID: 0030744209     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.138.8.5297     Document Type: Article

References (55)

1. scc-linked monooxygenase system in the adult rat brain. Biochim Biophys Acta 1035:182-189
2. Compagnone NA, Bulfone A, Rubenstein JL, Mellon SH 1995 Expression of the steroidogenic enzyme P450scc in the central and peripheral nervous system during rodent embryogenesis. Endocrinology 136:2689-2696
3. Strömstedt M, Waterman MR 1995 Messenger RNAs encoding steroidogenic enzymes are expressed in rodent brain. Brain Res Mol Brain Res 34:75-88
4. Belvedere P, Dalla Valle L, Ramina A, Simontacchi C, Colombo L, Occurrence of cytochrome P 450scc mRNA in the kidney, stomach and duodenum of the rat. 2nd International Symposium on Molecular Steroidogenesis, Monterey, CA, 1996, p P-16 (Abstract)
5. Rosner JM, Macome JC, Cardinali DP 1969 In vitro biosynthesis of sterols and steroids by rat submaxillary glands. Endocrinology 85:1000-1003
6. Naftolin F, Ryan KJ, Davies IJ, Reddy VV, Flores F, Petro Z, Kuhn M, White RJ, Takaoka Y, Wolin L 1975 The formation of estrogens by central neuroendocrine tissues. Recent Prog Horm Res 31:295-319
7. Lauber ME, Lichtensteiger W 1994 Pre- and postnatal ontogeny of aromatase cytochrome P450 messenger ribonucleic acid expression in the male rat brain studied by in situ hybridization. Endocrinology 135:1661-1668
8. Compagnone NA, Buflone A, Rubenstein JLR, Mellon SH 1995 Steroidogenic enzyme P450c17 is expressed in the embryonic central nervous system. Endocrinology 136:5212-5223
9. Savolainen T, Ojanotko A, Harry MP 1982 Metabolism of progesterone in small intestine of normal and pregnant rat. J Steroid Biochem 17:285 (Abstract 285)
10. Laine M, Ojanotko-Harry A1990 Progesterone metabolism by major salivary glands of rat. I. Submandibular and sublingual glands. J Steroid Biochem 35:723-728
11. Dalla Valle L, Belvedere P, Simontacchi C, Colombo L 1992 Extraglandular hormonal steroidogenesis in aged rats. J Steroid Biochem Mol Biol 43:1095-1098
12. Dalla Valle L, Couët J, Labrie Y, Simard J, Belvedere P, Simontacchi C, Labrie F, Colombo L 1995 Occurrence of cytochrome P450c17 mRNA and dehydroepiandrosterone biosynthesis in the rat gastrointestinal tract. Mol Cell Endocrinol 111:83-92
13. Le Goascogne C, Sananès N, Eychenne B, Gouézou M, Baulieu E-E, Robel P 1995 Androgen biosynthesis in the stomach: expression of cytochrome P450 17α-hydroxylase/ 17,20-lyase messenger ribonucleic acid and protein, and metabolism of pregnenolone and progesterone by parietal cells of the rat gastric mucosa. Endocrinology 136:1744-1752
14. Dalla Valle L, Ramina A, Vianello S, Belvedere P, Colombo L 1996 Kinetic analysis of duodenal and testicular cytochrome P450c17 in the rat. J Steroid Biochem Mol Biol 58:577-584
15. Miller WL 1988 Molecular biology of steroid hormone synthesis. Endocr Rev 9:295-318
16. Imaoka S, Kamataki T, Funae Y 1987 Purification and characterization of six cytochromes P-450 from hepatic microsomes of immature female rats. J Biochem 102:843-851
17. Swinney DC, Ryan DE, Thomas PE, Levin W 1987 Regioselective progesterone hydroxylation catalyzed by eleven rat hepatic cytochrome P-450 isozymes. Biochemistry 26:7073-7083
18. Trzaskos JM, Bowen WD, Shafiee A, Fisher RT, Gaylor JL 1984 Cytochrome P-450-dependent oxidation of lanosterol in cholesterol biosynthesis. J Biol Chem 259:13402-13412
19. Perrin A, Defaye G, Guidicelli C, Chambaz EM 1991 Purification and properties of steroid 17α-hydroxylase from calf testis. J Steroid Biochem Mol Biol 40:431-435
20. Imai T, Globerman H, Gertner JM, Kagawa N, Waterman MR 1993 Expression and purification of functional human 17α-hydroxylase/17,20-lyase (P450c17) in Escherichia coli. J Biol Chem 268:19681-19689
21. Sambrook J, Fritsch EF, Maniatis T 1989 Molecular Cloning: A Laboratory Manual, ed 2. Cold Spring Harbor Laboratory, Cold Spring Harbor
22. 17α cDNA: the deduced amino acid sequence, expression and secondary structural configuration. Biochem Biophys Res Commun 157:705-712
23. scc) in rat ovarian granulosa cells and corpora lutea. J Biol Chem 264:21934-21942
24. Lephart ED, Peterson KG, Noble JF, George FW, McPhaul MJ 1990 The structure of cDNA clones encoding the aromatase P-450 isolated from a rat Leydig cell tumor line demonstrates differential processing of aromatase mRNA in rat ovary and neoplastic cell line. Mol Cell Endocrinol 70:31-40
25. Casanova JL, Pannetier C, Jaulin C, Kourilsky P 1990 Optimal conditions for directly sequencing double-stranded PCR products with Sequenase. Nucleic Acids Res 18:4028
26. Bortolussi M, Zanchetta R, Belvedere P, Colombo L 1990 Sertoli and Leydig cell numbers and gonadotropin receptors in rat testis from birth to puberty Cell Tissue Res 260:185-191
27. 5-steroid-17,20-lyase reactions. Mol Endocrinol 3:968-975
28. Russel WE, DuBois RN 1994 The regulation of liver growth and regeneration. In: Suchy F (ed) Liver Disease in Children. Mosby-Year Book, St Louis pp 11-30
29. Givens CR, Zhang P, Bair SR, Mellon SH 1994 Transcriptional regulation of rat cytochrome P450c17 expression in mouse Leydig MA-10 and adrenal Y-1 cells: identification of a single protein that mediates both basal and cAMP-induced activities. DNA Cell Biol 13:1087-1098
30. Hyckey GJ, Krasnow JS, Beattie WG, Richards JS 1990 Aromatase cytochrome P450 in rat ovarian granulosa cells before and after luteinization: adenosine 3′,5′-monophosphate-dependent and independent regulation. Cloning and sequencing of rat aromatase cDNA and 5′ genomic DNA. Mol Endocrinol 4:3-12
31. ++ and TPA. 2nd International Symposium on Molecular Steroidogenensis, Monterey, CA, 1996, p 21 (Abstract)
32. Mellon SH, Miller WL 1989 Extraglandular steroid 21-hydroxylation is not mediated by P450c21. J Clin Invest 84:1497-1502
33. Endoh A, Natsume H, Igarashi Y 1995 Dual regulation of 21-hydroxylase activity by sex steroid hormones in rat hepatocytes. J Steroid Biochem Mol Biol 54:163-165
34. Murray M, Horsfield BP 1990 17β-Hydroxysteroid oxidoreductase activity: age-dependent profile in rat liver and kinetic properties of the hepatic microsomal enzyme in relation to cytochrome P450-dependent steroid hydroxylation. J Steroid Biochem 36:569-574
35. Song CS, Rao TR, Demyan WF, Mancini MA, Chatterjee B, Roy AK 1991 Androgen receptor messenger ribonucleic acid (mRNA) in the rat liver: changes in mRNA levels during maturation, aging, and calorie restriction. Endocrinology 128:349-356
36. Rumbaugh RC, McCoy Z, Lucier GW 1984 Correlation of hepatic cytosolic androgen binding proteins with androgen induction of hepatic microsomal ethylmorphine N-demethylase in the rat. J Steroid Biochem 21:243-252
37. Naville D, Keeney DS, Jenkin G, Murry BA, Head JR, Mason JI 1991 Regulation of expression of male-specific rat liver microsomal 3β-hydroxysteroid dehydrogenase. Mol Endocrinol 5:1090-1100
38. 4-isomerase activity in rat liver by sex steroids and pituitary hormones. Endocrinology 131:3034-3044
39. Zaphiropoulos PG, Mode A, Norstedt G, Gustafsson J-Å 1989 Regulation of sexual differentiation in drug and steroid metabolism. Trends Pharmacol Sci 10:149-153
40. Mode A, Tollet P, Stöm A, Legraverend C, Liddle C, Gustafsson J-Å 1992 Growth hormone regulation of hepatic cytochrome T450 expression in the rat. Adv Enzyme Regul 32:255-263
41. Waxman DJ, Dannan GA, Guengerich FP 1985 Regulation of rat cytochrome P-450:age-dependent expression, hormonal imprinting, and xenobiotic inducibility of sex-specific isoenzymes. Biochemistry 24:4409-4417
42. Lording DW, De Kretser DM 1972 Comparative ultrastructural and histochemical studies of the interstitial cells of the rat testis during fetal and post-natal development. J Reprod Fertil 29:261-269
43. Smeaton TC, Arcondoulis DE, Steele PA 1975 The synthesis of testosterone and estradiol-17β by the gonads of neonatal rats in vitro. Steroids 26:181-192
44. Hatano O, Takayama K, Imai T, Waterman MR, Takakusu A, Omura T, Morohashi K-i 1994 Sex-dependent expression of a transcription factor, Ad4BP, regulating steroidogenic P-450 genes in the gonads during prenatal and postnatal rat development. Development 120:2787-2797
45. Tsai-Morris C-H, Aquilano DR, Dufau ML 1985 Cellular localization of rat testicular aromatase activity during development. Endocrinology 116:38-46
46. Döhler KD, Wuttke W 1975 Changes with age in levels of serum gonadotropins, prolactin, and gonadal steroids in prepubertal male and female rats. Endocrinology 97:898-907
47. Carson R, Smith J 1986 Development and steroidogenic activity of preantral follicles in the neonatal rat ovary. J Endocrinol 110:87-92
48. Meijs-Roelofs HMA, Uilenbroek JTJ, de Jong FH, Welschen R 1973 Plasma oestradiol-17β and its relationship to serum follicle-stimulating hormone in immature female rats. J Endocrinol 59:295-304
49. Döhler KD, Wuttke W 1974 Serum LH, FSH, prolactin and progesterone from birth to puberty in female and male rats. Endocrinology 94:1003-1008
50. Mathews D, Andrews WW, Parker R, Ojeda SR 1987 A role for aromatizable androgens in female rat puberty. Biol Reprod 36:836-843
51. Bartova A 1968 Functioning of the hypotalamo-pituitary-adrenal system during postnatal development in rats. Gen Comp Endocrinol 10:235-239
52. Henning SJ 1978 Plasma concentrations of total and free corticosterone during development in the rat. Am J Physiol 235:E451-E456
53. Bolander FF 1989 Molecular Endocrinology. Academic Press, San Diego, p 48
54. Bolander FF 1989 Molecular Endocrinology. Academic Press, San Diego, p 16
55. Ojeda SR, Andrews WW, Advis JP, Smith White S 1980 Recent advances in the endocrinology of puberty. Endocr Rev 1:228-257