Parathyroid hormone (PTH 1-34) regulation of rat osteocalcin gene transcription

Endocrinology

Volumn 138, Issue 8, 1997, Pages 3085-3092

  Yu, Xiao Peng ^a   Chandrasekhar, Srinivasan ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; CYCLIC AMP DEPENDENT PROTEIN KINASE; FORSKOLIN; OSTEOCALCIN; PARATHYROID HORMONE[1-34];

ARTICLE; BONE MINERALIZATION; CALCIUM MOBILIZATION; CELL DIFFERENTIATION; CONTROLLED STUDY; CYCLIC AMP RESPONSIVE ELEMENT; EXTRACELLULAR MATRIX; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; OSSIFICATION; OSTEOBLAST; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 0030744207     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.138.8.5315     Document Type: Article

References (43)

1. 3. Biochemistry 27:8521-8526
2. Desbois C, Hogue DA, Karsenty G 1994 The mouse osteocalcin gene cluster contains three genes with two separate spatial and temporal patterns of expression. J Biol Chem 269:1183-1190
3. Celeste AJ, Rosen V, Buecker JL, Kriz R, Wang EA, Wozney JM 1986 Isolation of the human gene for bone gla protein utilizing mouse and rat cDNA clones. EMBO J 5:1885-1890
4. Rahman S, Oberdorf A, Montecino M, Tanhauser SM, Lian JB, Stein GS, Laipis PJ, Stein JL 1993 Multiple copies of the bone-specific osteocalcin gene in mouse and rat. Endocronology 133:3050-305
5. Baker AR, Hollingshead PG, Pitts-Meek S, Hansen S, Taylor R, Stewart TA 1992 Osteoblast-specific expression of growth hormone stimulates bone growth in transgenic mice. Mol Cell Biol 12:5541-5547
6. Kesterson RA, Stanley L, DeMayo F, Finegold M, Pike JW 1993 The human osteocalcin promoter directs bone-specific vitamin D-regulated gene expression in transgenic mice. Mol Endocrinol 7:462-467
7. Lian J, Stewart C, Puchac E, Mackowiak S, Shalhour V, Collart D, Zambetti G, Stein G 1989 Structure of the rat osteocalcin gene and regulation of vitamin D-dependent expression. Proc Natl Acad Sci USA 86:1143-1147
8. Morrison NA, Shine J, Fragonas J, Verkest V, McMenemy ML, Eisman JA 1989 1,25-dihydroxyvitamin D-responsive element and glucocorticoid repression in the osteocalcin gene. Science 246:1158-1161
9. Ozono K, Liao J, Kerner SA, Scott RA, Pike JW 1990 The vitamin D-responsive element in the human osteocalcin gene. J Biol Chem 265:21881-21888
10. Stromstedt PE, Poellinger L, Gustafsson JA, Carlstedt-Duke J 1991 The glucocorticoid receptor binds to a sequence overlapping the TATA box of the human osteocalcin promoter: a potential mechanism for negative regulation. Mol Cell Biol 11:3379-3383
11. Reeve J, Meunier PJ, Parsons JA, Bernat M, Bijvoet OLM, Courpron P, Edouard C, Klenerman L, Neer RM, Renier JC, Slovik D, Visman FJ, Potts JT 1980 Anabolic effect of human parathyroid hormone fragment on trabecular bone in involutional osteoporosis: a multicentre trial. Br Med J 280:1340-1344
12. Hefti E, Trechsel U, Bonjour JP, Fleisch H, Scheak R 1982 Increase of wholebody calcium and skeletal mass in normal and osteoporotic adult rats treated with parathyroid hormone. Clin Sci 62:389-396
13. Podbesek R, Edouard C, Meunier PJ, Parsons JA, Reeve J, Stevenson RW, Zanelli JM 1983 Effects of two treatment regimes with synthetic human parathyroid hormone fragment on bone formation and the tissue balance of trabecular bone in greyhounds. Endocrinology 112:1000-1006
14. Gunness-Hey M, Hock JM 1984 Increased trabecular bone mass in rats treated with human synthetic parathyroid hormone. Metab Bone Dis Relat Res 5:177-181
15. Hori M, Uzawa T, Morita K, Noda T, Takahashi H, Inoue J 1988 Effect of human parathyroid hormone (PTH 1-34) on experimental osteopenia of rats induced by ovariectomy. Bone Miner 3:193-199
16. Hock JM, Onyia JE, Miller B, Hulman J, Herring J, Chandraskhar S, Harvey AK, Gunness-Hey M 1994 Anabolic PTH targets proliferating cells of the primary spongiosa in young rats, and increases the number differentiating into osteoblasts. J Bone Miner Res 9[Suppl 1]:S412 (Abstract)
17. Juppner H, Abou-Samra AB, Freeman M, Kong, XF, Schipani E, Richards J, Kolakowski LF, Hock JM, Potts JT, Kronenberg HM, Segre GV 1991 A G protein-linked receptor for parathyroid hormone and parathyroid hormone-related peptide. Science 254:1024-1026
18. Abou-Samra AB, Juppner H, Torce T, Freeman M, Kong XF, Schipani E, Urena P, Richards J, Bonventre JV, Potts JT, Kronenberg HM, Segre GV 1992 Expression cloning of a common receptor for parathyroid hormone and parathyroid hormone-related peptide from rat osteoblast-like cells: a single receptor stimulates intracellular accumulation of both cAMP and inositol trisphosphates and increases intracellular free calcium. Proc Natl Acad Sci USA 89:2732-2736
19. Schipani E, Karga H, Karaplis AC, Potts JT, Kronenberg HM, Segre GV. Abou-Samra AB, Juppner H 1993 Identical complementary deoxyribonucleic acids encode a human renal and bone parathyroid hormone (PTH)/PTH-related peptide receptor. Endocrinology 132:2157-2165
20. Chase LR, Aurbach GD 1970 The effect of parathyroid hormone on the concentration of adenosine 3′,5′-monophosphate in skeletal tissue in vitro. J Biol Chem 245:1520-1526
21. 2, and prostacyclin. Endocrinology 108:220-225
22. Civitelli R, Reid IR, Westbrook S, Avioli LV, Hruska, KA 1988 PTH elevates inositol polyphosphates and diacylglycerol in a rat osteoblast-like cell line. Am J Physiol 255:E660-E667
23. Reid IR, Civitelli R, Halstead LR, Avioli LV, Hruska KA 1987 Parathyroid hormone acutely elevates intracellular calcium in osteoblastlike cells. Am J Physiol 252:E45-E51
24. Yamaguchi DT, Hahn TJ, Iida-Klein A, Kleeman CR, Muallem S 1987 Parathyroid hormone-activated calcium channels in an osteoblast-like clonal osteosarcoma cell line. J Biol Chem 262:7711-7718
25. Mallette LE 1994 Parathyroid hormone and parathyroid hormone- related protein as polyhormones. In: Bilezikian JP, Levine MA, Marcus R (eds) The Parathyroids. Raven Press, New York, pp 171-184
26. Noda M, Yoon K, Rodan GA 1988 Cyclic AMP-mediated stabilization of osteocalcin mRNA in rat osteoblast-like cells treated with parathyroid hormone. J Biol Chem 263:18574-18577
27. Towler DA, Roden GA 1995 Identification of a rat osteocalcin promoter 3′,5′-cyclic adenosine monophosphate response region containing two PuG-GTCA steroid hormone receptor binding motifs. Endocrinology 136:1089-1096
28. Fukayama S, Tashjian AH, Jr, Bringhurst FR 1992 Mechanisms of desensitization to parathyroid hormone in human osteoblast-like SaOS-2 cells. Endocrinology 131:1757-1769
29. Nesterova M, Cho-Chung YS 1995 A single-injection protein kinase A-directed antisense treatment to inhibit tumour growth. Nature Med 1:528-533
30. Chiang MY, Chan H, Zounes MA, Freier SM, Lima WF, Bennet CF 1991 Antisense oligonucleotides inhibit intercellular adhesion molecule 1 expression by two distinct mechanisms. J Biol Chem 266:18162-18171
31. Chijiwa T, Mishima A, Hagiwara M, Sano M, Hayashi K, Inoue T, Naito K, Toshioka T, Hidaka H 1990 Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide (H-89), of PC12D pheochromocytoma cells. J Biol Chem 265:5267-5272
32. 2+-binding protein of bone matrix. Haemostasis 16:258-272
33. Frenkel B, Mijines J, Aronow MA, Zambetti G, Banerjee C, Stein JL, Lian JB, Stein GS 1993 Position and orientation-selective silencer in protein-coding sequences of the rat osteocalcin gene. Biochemistry 32:13636-13643.
34. Dempster DW, Cosman F, Parisien M, Shen V, Lindsay R 1993 Anabolic actions of parathyroid hormone on bone. Endocr Rev 14:690-709
35. Canalis E, Hock JM, Raisz LG 1994 Anabolic and catabolic effects of parathyroid hormone on bone and interactions with growth factors. In: Bilezikian JP, Levine MA, Marcus R (eds) The Parathyroids Raven Press, New York, pp 65-82
36. Rixon RH, Whitfield JF, Gagnon L, Isaacs RJ, Maclean S, Chakravarthy B, Durkin JP, Neugebauer W, Ros V, Sung W, Willick GE 1994 Parathyroid hormone fragments may stimulate bone growth in ovariectomized rats by activating adenylyl cyclase. J Bone Miner Res 9:1179-1189
37. Jouishomme H, Whitfield JF, Gagnon L, Maclean S, Isaacs RJ, Chakravarthy B, Durkin JP, Neugebauer W, Willick GE, Rixon RH 1994 Further definition of the protein kinase C activation domain of the parathyroid hormone. J Bone Miner Res 9:943-949
38. Fujimori A, Cheng SL, Aviooli LV, Civitelli R 1992 Structure-function relationship of parathyroid hormone: activation of phospholipase-C, protein kinase-A and -C in osteosarcoma cells. Endocrinology 130:29-36
39. Jouishomme H, Whitfield JF, Chakravarthy B, Durkin JP, Gagnon L, Isaacs RJ, Maclean S, Neugebauer W, Willick GE, Rixon RH 1992 The protein kinase-C activation domain of the parathyroid hormone. Endocrinology 130:53-59
40. Laurenza A, Sutkowski EM, Seamon KB 1989 Forskolin: a specific stimulator of adenylate cyclase or a diterpene with multiple sites of actions? Trends Phramcol Sci 10:442-447
41. Minor LK, Yang M, Westover L 1996 Forskolin but not sodium fluoride (NAF) potentiates the action of parathyroid hormone (PTH) and vasoactive intestinal peptide (VIP) on adenylate cyclase activity in SaOS-2 osteosarcoma cells. Mol Biol Cell 75:2505 (Abstract)
42. Fukayama S, Tashjian AH, Jr, Bringhurst RF 1992 Forskolin-induced homologous desensitization via an adenosine 3′,5′-monophosphate-dependent mechanism(s) in human osteoblast-like SaOS-2 cells. Endocrinology 131:1770-1776
43. Ducy P, Desbois C, Boyce B, Pinero G, Story B, Dunstan C, Smith E, Bonadio J, Goldstein S, Gundberg C, Bradley A, Karsenty G 1996 Increased bone formation in osteocalcin-deficient mice. Nature 382:448-452