Mutation of a protease-sensitive region in firefly luciferase alters light emission properties

Journal of Biological Chemistry

Volumn 272, Issue 30, 1997, Pages 18766-18771

  Thompson, John F ^a   Geoghegan, Kieran F ^a   Lloyd, David B ^a   Lanzetti, Anthony J ^a   Magyar, Rachelle A ^a,b   Anderson, Shannon M ^a,b   Branchini, Bruce R ^a,b  

^a PFIZER INC   (United States)

^b The Department of Government and International Relations   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHYMOTRYPSIN; LUCIFERASE; TRYPSIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ENZYME ANALYSIS; FIREFLY; GENE MUTATION; LUMINESCENCE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; REPORTER GENE; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; ANIMALS; BEETLES; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HYDROGEN-ION CONCENTRATION; KINETICS; LUCIFERASES; LUMINESCENT MEASUREMENTS; MOLECULAR SEQUENCE DATA; MUTATION; SEQUENCE HOMOLOGY, AMINO ACID;

ANIMALIA; PHOTINUS PYRALIS; PYRALIS;

EID: 0030743408     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.30.18766     Document Type: Article

References (18)

1. Gould, S. J., and Subramani, S. (1988) Anal. Biochem. 175, 5-13
2. Seliger, H. H., and McElroy, W. D. (1960) Arch. Biochem. Biophys. 88, 136-141
3. Airth, R. L., Rhodes, W. C., and McElroy, W. D. (1958) Biochim. Biophys. Acta 27, 519-532
4. Pazzagli, M., Devine, J. H., Peterson, D. O., and Baldwin, T. O. (1992) Anal. Biochem. 204, 315-323
5. Ortiz, B., Fernandez, V. M., Gunther-Sillero, M. A., and Sillero, A. (1995) J. Photochem. Photobiol. B Biol. 29, 33-36
6. de Wet, J. R., Wood, K. V., DeLuca, M., Helinski, D. R., and Subramani, S. (1987) Mol. Cell. Biol. 7, 725-737
7. Wood, K. V. (1995) Photochem. Photobiol. 62, 662-673
8. Suzuki, H., Kawarabayasi, Y., Kondo, J., Abe, T., Nishikawa, K., Kimura, S., Hashimoto, T., and Yamamoto, T. (1990) J. Biol. Chem. 265, 8681-8685
9. Babbitt, P. C., Kenyon, G. L., Martin, B. M., Charest, H., Slyvestre, M., Scholten, J. D., Chang, K.-H., Liang, P.-H., and Dunaway-Mariano, D. (1992) Biochemistry 31, 5594-5604
10. Conti, E., Franks, N. P., and Brick, P. (1996) Structure (Lond.) 4, 287-298
11. Thompson, J. F., Hayes, L. S., and Lloyd, D. B. (1991) Gene (Amst.) 103, 171-177
12. Branchini, B. R., Hayward, M. M., Bamford, S., Brennan, P. M., and Lajiness, E. J. (1989) Photochem. Photobiol. 49, 689-695
13. Branchini, B. R., Magyar, R. A., Murtishaw, M. H., Magnasco, N., Hinz, L. K., and Stroh, J. G. (1997) Arch. Biochem. Biophys. 340, 52-58
14. Dementieva, E. I., Zheleznova, E. E., Kutuzova, G. D., Lundovskikh, I. A., and Ugarova, N. N. (1996) Biochemistry (Moscow) 61, 115-119
15. Gocht, M., and Marahiel, M. A. (1994) J. Bacteriol. 176, 2654-2662
16. Pavela-Vrancic, M., Pfeifer, E., van Liempt, H., Schäfer, H.-J., von Döhren, H., and Kleinkauf, H. (1994) Biochemistry 33, 6276-6283
17. Viviani, V. R., and Bechara, E. J. H. (1995) Photochem. Photobiol. 62, 490-495
18. Ford, S. R., Buck, L. M., and Leach, F. R. (1995) Biochim. Biophys. Acta 1252, 180-184