Ultrastructural analysis of primary endings in deaf white cats: Morphologic alterations in endbulbs of held

Journal of Comparative Neurology

Volumn 385, Issue 2, 1997, Pages 230-244

  Ryugo, D K ^a   Pongstaporn, T ^a   Huchton, D M ^a   Niparko, J K ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Auditory nerve; Cochlear nucleus; Congenital deafness; Hearing; Synapses

Indexed keywords

ANIMAL TISSUE; ARTICLE; CAT; CELL DENSITY; CELL ULTRASTRUCTURE; COCHLEAR NERVE; COCHLEAR NUCLEUS; CONGENITAL DEAFNESS; EVOKED AUDITORY RESPONSE; NERVE ENDING; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; SYNAPSE VESICLE; SYNAPTIC TRANSMISSION;

ANIMALS; AUDITORY PATHWAYS; CATS; COCHLEAR NUCLEUS; DEAFNESS; DISEASE MODELS, ANIMAL; FEMALE; MALE; MICROSCOPY, ELECTRON; NERVE ENDINGS; PRESYNAPTIC TERMINALS;

EID: 0030743298     PISSN: 00219967     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9861(19970825)385:2<230::AID-CNE4>3.0.CO;2-2     Document Type: Article

References (80)

1. Aboujaoude, E.S., J.K. Niparko, and D.K. Ryugo (1996) Fractal analysis of endbulbs of Held in cats. ARO Abstr. 19:171.
2. Bailey, C.H., and M. Chen (1983) Morphological basis of long-term habituation and sensitization in Aplysia. Science 220:91-93.
3. Bakin, J.S., and N.M. Weinberger (1990) Classical conditioning induces CS-specific receptive field plasticity in the auditory cortex of the guinea pig. Brain Res. 536:271-286.
4. Benes, F.M., T.N. Parks, and E.W Rubel (1977) Rapid dendritic atrophy following deafferentation: An EM morphometric analysis. Brain Res. 122:1-13.
5. Benson, T.W., D.K. Ryugo, and J.W. Hinds (1984) Effects of sensory deprivation on the developing mouse olfactory system: A light and electron microscopic, morphometric analysis. J. Neurosci. 4:638-653.
6. Bergsma, D., and K. Brown (1971) White fur, blue eyes, and deafness in the domestic cat. J. Hered. 62:171-185.
7. Born, D.E., and E.W. Rubel (1985) Afferent influences on brain stem auditory nuclei of the chicken: Neuron number and size following cochlea removal. J. Comp. Neurol. 231:435-445.
8. Born, D.E., D. Durham, and E.W. Rubel (1991) Afferent influences on brainstem auditory nuclei of the chick: Nucleus magnocellularis neuronal activity following cochlea removal. Brain Res. 557:37-47.
9. Bosher, S.K., and C.S. Hallpike (1965) Observations on the histological features, development and pathogenesis of the inner ear degeneration of the deaf white cat. Proc. R. Soc. Lond. B 162:147-170.
10. Brighton, P., R. Ramesar, I. Winship, D. Viljoen, J. Greenberg, K. Young, D. Curtis, and S. Sellars (1991) Hearing impairment and pigmentary disturbance. Ann. NY Acad. Sci. 630:152-166.
11. Cant, N.B., and D.K. Morest (1979) Organization of the neurons in the anterior division of the anteroventral cochlear nucleus of the cat. Light-microscopic observations. Neuroscience 4:1909-1923.
12. Desmond, N.L., and W.B. Levy (1986) Changes in the postsynaptic density with long-term potentiation in the dentate gyrus. J. Comp. Neurol. 253:476-482.
13. Deitch, J.S., and E.W. Rubel (1984) Afferent influences on brain stem auditory nuclei of the chicken: Time course and specificity of dendritic atrophy following deafferentation. J. Comp. Neurol. 229:66-79.
14. Deitch, J.S., and E.W. Rubel (1989a) Changes in neuronal cell bodies in N. laminaris during deafferentation-induced dendritic atrophy. J. Comp. Neurol. 281:259-268.
15. Deitch, J.S., and E.W. Rubel (1989b) Rapid changes in ultrastructure during deafferentation-induced dendritic atrophy. J. Comp. Neurol. 281:234-258.
16. Deol, M.S. (1970) The relationship between abnormalities of pigmentation and of the inner ear. Proc. R. Soc. Lond. 175:201-217.
17. Durham, D., and T.A. Woolsey (1984) Effects of neonatal whisker lesions on mouse central trigeminal pathways. J. Comp. Neurol. 223:424-447.
18. Fekete, D.M., E.M. Rouiller, M.C. Liberman, and D.K. Ryugo (1984) The central projections of intracellularly labeled auditory nerve fibers in cats. J. Comp. Neurol. 229:432-450.
19. Fernandez, E., W.D. Eldred, J. Ammermüller, A. Block, W. Von Bloh, and H. Kolb (1994) Complexity and scaling properties of amacrine, ganglion, horizontal, and bipolar cells in the turtle retina. J. Comp. Neurol. 347:397-408.
20. + channels and ankyrin in neuromuscular junctions is complementary to that of acetylcholine receptors and the 43 KD protein. Neuron 3:163-175.
21. Gantz, B., R. Tyler, G. Woodworth, N. Tye-Murray, and H. Fryauf-Bertschy (1994) Results of multichannel cochlear implants in congenital and acquired prelingual deafness in children: Five year follow up. Am. J. Otol. 15:1-8.
22. Gray, E.G., and R.W. Guillery (1966) Synaptic morphology in the normal and degenerating nervous system. Int. Rev. Cytol. 19:111-182.
23. Greenough, W.T., R.W. West, and T.J. DeVoodg (1978) Subsynaptic plate perforations: Changes with age and experience in the rat. Science 202:1096-1098.
24. Gulley, R.L., D.M.D. Landis, and T.S. Reese (1978) Internal organization of membranes at endbulbs of Held in the anteroventral cochlear nucleus. J. Comp. Neurol. 180:707-742.
25. Hashisaki, G.T., and E.W. Rubel (1989) Effects of unilateral cochlea removal on anteroventral cochlear nucleus neurons in developing gerbils. J. Comp. Neurol. 283:5-73.
26. Held, H. (1893) Die centrale gehörleitung. Arch. Physiol. Anat. 201-248.
27. Hillman, D.E., and S. Chen (1985) Plasticity in the size of presynaptic and postsynaptic membrane specializations. In C.W. Cotman (ed): Synaptic Plasticity. New York: Guilfbrd Press, pp. 39-75.
28. Ibata, Y., and G.D. Pappas (1976) The fine structure of synapses in relation to the large spherical neurons in the anterior ventral cochlear (sic) of the cat. J. Neurocytol. 5:395-406.
29. Larsen, S.A., and T.M. Kirchhoff (1992) Anatomical evidence of plasticity in the cochlear nuclei of deaf white cats. Exp. Neurol. 115:151-157.
30. Lenn, N.J., and T.S. Reese (1966) The fine structure of nerve endings in the nucleus of the trapezoid body and the ventral cochlear nucleus. Am. J. Anat. 118:375-390.
31. Lesperance, M.M., R.H. Helfert, and R.A. Altschuler (1995) Deafness induced cell size changes in rostral AVCN of the guinea pig. Hear. Res. 86:77-81.
32. Lorente de Nó, R. (1981) The Primary Acoustic Nuclei. New York: Raven Press.
33. Lustig, L.R., P.A. Leake, R.L. Snyder, and S.J. Rebscher (1994) Changes in the cat cochlear nucleus following neonatal deafening and chronic intracochlear electrical stimulation. Hear. Res. 74:29-37.
34. Mair, I.W. (1973) Hereditary deafness in the white cat. Acta. Otolaryngol. 314:1-48.
35. Mandelbrot, B.B. (1982) The Fractal Geometry of Nature. New York: Freeman.
36. Melcher, J.R., J.J. Guinan, Jr., I.M. Knudson, and N.Y.S. Kiang (1996) Generators of the brainstem auditory evoked potential in cat. II. Correlating lesion sites with waveform changes. Hear. Res. 93:28-51.
37. Molnar, C.E., and R.R. Pfeiffer (1968) Interpretation of spontaneous spike discharge patterns of neurons in the cochlear nucleus. Proceed. IEEE 56:993-1004.
38. Moore, D.R. (1990) Auditory brainstem of the ferret: Early cessation of developmental sensitivity of neurons in the cochlear nucleus to removal of the cochlea. J. Comp. Neurol. 302:810-823.
39. Moore, D.R., and N.B. Kowalchuk (1988) Auditory brainstem of the ferret: Effects of unilateral cochlear lesions on cochlear nucleus volume and projections to the inferior colliculus. J. Comp. Neurol. 272:503-515.
40. Moore, J.K., J.K. Niparko, M. Miller, and F. Linthicum (1994) Effect of profound deafness on a central auditory nucleus. Am. J. Otol. 15:588-595.
41. Nordeen, K.W., H.P. Killackey, and L.M. Kitzes (1983) Ascending projections to the inferior colliculus following unilateral cochlear ablation in the neonatal gerbil, Meriones uniguiculatus. J. Comp. Neurol. 214:144-153.
42. Nusser, Z., E. Mulvihill, P. Streit, and P. Somogyi (1994) Subsynaptic segregation of metabotropic and ionotropic glutamate receptors as revealed by immunogold localization. Neuroscience 61:421-427.
43. Palay, S.L., and V. Chan-Palay (1974) Cerebellar Cortex, Cytology and Organization. New York: Springer-Verlag.
44. Panico, J., and P. Sterling (1995) Retinal neurons and vessels are not fractal but space-filling. J. Comp. Neurol. 361:479-490.
45. Parks, T.N. (1979) Afferent influences on the development of the brain stem auditory nuclei of the chicken: Otocyst ablation. J. Comp. Neurol. 183:665-677.
46. Parks, T.N., D.A. Taylor, and H. Jackson (1990) Adaptations of synaptic form in an aberrant projection to the avian cochlear nucleus. J. Neurosci. 10:975-984.
47. Pasic, T.R., D.R. Moore, and E.W. Rubel (1994) Effect of altered neuronal activity on cell size in the medial nucleus of the trapezoid body and ventral cochlear nucleus of the gerbil. J. Comp. Neurol. 348:111-120.
48. Pfeiffer, R.R. (1966) Anteroventral cochlear nucleus: Wave forms of extracellularly recorded spike potentials. Science 154:667-668.
49. Porter, R., S. Ghosh, G.D. Lange, and T.G. Smith, Jr. (1991) A fractal analysis of pyramidal neurons in mammalian motor cortex. Neurosci. Lett. 130:112-116.
50. Powell, T.P.S., and S.D. Erulkar (1962) Transneuronal cell degeneration in the auditory relay nuclei of the cat. J. Anat. 96:219-268.
51. Pujol, R., M. Rebillard, and G. Rebillard (1977) Primary neural disorders in the deaf white cat cochlea. Acta Otolaryngol. 83:59-64.
52. Ramón y Cajal, R. (1909) Histologie du Système Nerveux de l'Homme et des Vertébrés. Paris: A. Maloine.
53. Rawitz, B. (1896) Gehörorgan und gehirn eines weissen hundes mit blauen augen. Morphol. Arbeit. 6:545-554.
54. Rebillard, M., G. Rebillard, and R. Pujol (1981) Variability of the hereditary deafness in the white cat. I. Physiology. Hear. Res. 5:179-181.
55. Recanzone, G.H., C.E. Schreiner, and M.M. Merzenich (1993) Plasticity in the frequency representation of primary auditory cortex following discrimination training in adult owl monkeys. J. Neurosci. 13:87-103.
56. Rees, S., F.H. Guldner, and L. Atikin (1985) Activity dependent plasticity of postsynaptic density structure in the ventral cochlear nucleus of the rat. Brain Res. 325:370-374.
57. Robertson, D., and D.R. Irvine (1989) Plasticity of frequency organization in auditory cortex of guinea pigs with partial unilateral deafness. J. Comp. Neurol. 282:456-471.
58. Rubel, E.W., and T.N. Parks (1988) Organization and development of the avian brain-stem auditory system. In G.M. Edelman, W.E. Gall, and W.M. Cowan (eds): Auditory Function - Neurobiologial Bases of Hearing. New York: John Wiley & Sons, pp. 3-92.
59. Ryugo, D.K. (1992) The auditory nerve: Peripheral innervation, cell body morphology, and central projections. In D.B. Webster, A.N. Popper, and R.R. Fay (eds): Mammalian Auditory Pathway: Neuroanatomy. New York: Springer-Verlag, pp. 23-65.
60. Ryugo, D.K., and D.M. Fekete (1982) Morphology of primary axosomatic endings in the anteroventral cochlear nucleus of the cat: A study of the endbulbs of Held. J. Comp. Neurol. 210:239-257.
61. Ryugo, D.K., and S. Sento (1991) Synaptic connections of the auditory nerve in cats: Relationship between endbulbs of Held and spherical bushy cells. J. Comp. Neurol. 305:35-48.
62. Ryugo, D.K., M.M. Wu, and T. Pongstaporn (1996) Activity related features of synapse morphology: A study of the endbulbs of Held. J. Comp. Neurol. 365:141-158.
63. Saada, A.A., P.J. Kim, D.R. Vause, J.K. Niparko, and D.K. Ryugo (1995) Auditory nerve activity and structural integrity of cochlear neural elements in the deaf white cat. Assn. Res. Otolaryngol. Abstr. 18:176.
64. Saada, A.A., J.K. Niparko, and D.K. Ryugo (1996) Morphological changes in the cochlear nucleus of congenitally deaf white cats. Brain Res. 736:315-328.
65. Scheibe, A. (1892) A case of deaf-mutism, with auditory atrophy and anomalies of development in the membranous labyrinth of both ears. Arch. Otolaryngol. 21:12-22.
66. Schwartz, I.R., and J.F. Higa (1982) Correlated studies of the ear and brainstem in the deaf white cat: Changes in the spiral ganglion and the medial superior olivary nucleus. Acta Otolaryngol. 93:9-18.
67. Seitanidou, T., A. Triller, and H. Korn (1988) Distribution of glycine receptors on the membrane of a central neuron: an immunoelectron microscopy study. J. Neurosci. 8:4319-4333.
68. Seldon, H.L., and G.M. Clark (1991) Human cochlear nucleus: Comparison of Nissl-stained neurons from deaf and hearing patients. Brain Res. 551:185-194.
69. Sento, S., and D.K. Ryugo (1989) Endbulbs of Held and spherical bushy cells in cats: Morphological correlates with physiological properties. J. Comp. Neurol. 280:553-562.
70. Sie, K.C., and E.W. Rubel (1992) Rapid changes in protein synthesis and cell size in the cochlear nucleus following eighth nerve activity blockade or cochlea ablation. J. Comp. Neurol. 320:501-508.
71. Smith, T.G., Jr., W.B. Marks, G.D. Lange, W.H. Sheriff, Jr., and E.A. Neale (1989) A fractal analysis of cell images. J. Neurosci. Methods 27:173-180.
72. Suga, F., and K.W. Hattler (1970) Physiological and histopathological correlates of hereditary deafness in animals. Laryngoscope 80:81-104.
73. Sullivan, W.E., and M. Konishi (1984) Segregation of stimulus phase and intensity coding in the cochlear nucleus of the barn owl. J. Neurosci. 4:1787-1799.
74. Treeck, H.H., and W. Pirsig (1979) Differentiation of nerve endings in the cochlear nucleus on morphological and experimental basis. Acta Otolaryngol. 87:47-60.
75. Trune, D.R. (1982) Influence of neonatal cochlear removal on the development of mouse cochlear nucleus. I. Number, size, and density of its neurons. J. Comp. Neurol. 209:409-424.
76. Waltzman, S.B., N.L. Cohen, and W.H. Shapiro (1992) Use of a multichannel cochlear implant in the congenitally and prelingually deaf population. Laryngoscope 102:395-399.
77. Waltzman, S., S. Fisher, J.K. Niparko, and N. Cohen (1994) Predictors of postoperative performance with cochlear implants. Ann. Otol. Rhinol. Laryngol. 165:15-18.
78. West, C.D., and J. Harrison (1973) Transneuronal cell atrophy in the deaf white cat. J. Comp. Neurol. 151:377-398.
79. Wiesel, T.N., and D.H. Hubel (1963) Effects of visual deprivation on morphology and physiology of cells in the cat's lateral geniculate body. J. Neurophysiol. 26:973-993.
80. Wolff, D. (1942) Three generations of deaf white cats. J. Hered. 33:39-43.