Local control of ovarian steroidogenesis

Bailliere's Clinical Obstetrics and Gynaecology

Volumn 11, Issue 2, 1997, Pages 261-279

  Mason, H ^a   Franks, S ^a  

^a IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

Author keywords

Granulosa; Insulin; Insulin like growth factors; Polycystic ovaries; Steroidogenesis; Theca

Indexed keywords

ANDROGEN; ANDROSTENEDIONE; ESTRADIOL; FOLLITROPIN; INSULIN; PROGESTERONE; PROTEINASE; SOMATOMEDIN; SOMATOMEDIN BINDING PROTEIN; STEROID; TRANSFORMING GROWTH FACTOR ALPHA;

ANDROGEN SYNTHESIS; FEMALE; GRANULOSA CELL; HORMONAL REGULATION; HUMAN; OVARY; OVARY FOLLICLE DEVELOPMENT; OVARY POLYCYSTIC DISEASE; PRIORITY JOURNAL; REVIEW; STEROIDOGENESIS; THECA CELL;

EID: 0030742848     PISSN: 09503552     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0950-3552(97)80037-5     Document Type: Article

References (95)

1. Adams J Polson DW Abdulwahid N Multifollicular ovaries: clinical and endocrine features and response to pulsatile gonadotrophin releasing hormone Lancet ii 1985 1375 1378
2. Adams J Polson DW Franks S Prevalence of polycystic ovaries in women with anovulation and idiopathic hirsutism British Medical Journal 293 1986 355 359
3. Adashi EY Resnick CE Hurwitz A Ovarian granulosa cell-derived insulin-like growth factor binding proteins: modulatory role of follicle stimulating hormone Endocrinology 128 1991 754 761
4. Angervo M Koistinen R Suikkari AM Insulin-like growth factor binding protein-1 inhibits the DNA amplification induced by insulin-like growth factor in human granulosa-luteal cells Human Reproduction 6 1991 770 773
5. (supplement) Baird DT Hillier G Reddi K Bioactive serum FSH in clomiphene responsive and non-responsive subjects with polycystic ovary syndrome Journal of Endocrinology 118 1988 S257
6. Barbieri RL Ryan K Hyperandrogenism, insulin resistance and acanthosis nigricans syndrome: a common endocrinopathy with distinct pathophysiologic features American Journal of Obstetrics and Gynecology 147 1983 90 100
7. Barbieri RL Makris A Randall RW Insulin stimulates androgen accumulation in incubations of ovarian stroma and theca Journal of Clinical Endocrinology and Metabolism 62 1986 904 910
8. Bergh C Carlsson B Olsson JH Regulation of androgen production in cultured human thecal cells by insulin-like growth factor-I and insulin Fertility and Sterility 59 1993 323 331
9. Bicsak TA Shimonaka M Malkowski M Ling N Insulin-like growth factor binding protein (IGFBP) inhibition of granulosa cell function: effect on cyclic adenosine 3′,5′-monophosphate, deoxyribonucleic acid synthesis, and comparison with the effect of an IGF-I antibody Endocrinology 126 1990 2184 2189
10. Burghen GA Givens JR Kitabchi AE Correlation of hyperandrogenism with hyperinsulinaemia in polycystic ovarian disease Journal of Clinical Endocrinology and Metabolism 50 1980 113 116
11. Cara JF Rosenfield RL Insulin-like growth factor-I and insulin potetiate luteinizing hormone-induced androgen synthesis by rat ovarian thecal-interstitial cells Endocrinology 123 1988 733 739
12. Carey AH Chan KL Short F Evidence for a single gene effect causing polycystic ovaries and male pattern baldness Clinical Endocrinology 38 1993 653 658
13. Carey AH Waterworth D Patel K Polycystic ovaries and premature male pattern baldness are associated with one allele of the steroid metabolism gene CYP17 Human Molecular Genetics 3 1994 1873 1876
14. Cataldo NC Giudice LC Follicular fluid insulin-like growth factor binding protein profiles in polycystic ovary syndrome Journal of Clinical Endocrinology and Metabolism 74 1992 695 697
15. Clayton RN Ogden V Hodgkinson J How common are polycystic ovaries in normal women and what is their significance for the fertility of the general population? Clinical Endocrinology 37 1992 127 134
16. Cohen P Graves HBC Peehl DM Prostate-specific antigen (PSA) is an insulin-like growth factor binding protein-3 protease found in seminal plasma Journal of Clinical Endocrinology and Metabolism 75 1992 1046 1053
17. Conway GS Honour JW Jacobs HS Heterogeneity of the polycystic ovary syndrome; clinical, endocrine and ultrasound features in 556 patients Clinical Endocrinology 30 1989 459 470
18. Cooper H Spellacy W Prem K Hereditary factors in the Stein-Leventhal syndrome American Journal of Obstetrics and Gynaecology 100 1968 371 387
19. Cwyfan-Hughes SC Cotterill AM Molloy AR The induction of specific proteases for insulin-like growth factor-binding proteins following major heart surgery Journal of Endocrinology 135 1992 135 145
20. Derynck R Transforming growth factor α: structure and biological activities Journal of Cell Biochemistry 32 1986 293 300
21. Dunaif A Graf M Mandeli J Characterisation of groups of hyperandrogenic women with acanthosis nigricans, impaired glucose tolerance and/or hyperinsulinaemia Journal of Clinical Endocrinology and Metabolism 65 1987 499 507
22. Ehrmann DA Barnes RB Rosenfield RL Polycystic ovary syndrome as a form of functional ovarian hyperandrogenism due to dysregulation of androgen secretion Endocrine Reviews 16 1995 322 353
23. El-Roeiy A Chen X Roberts VJ Expression of the genes encoding the insulin-like growth factors (IGF-I and II), the IGF and insulin receptors and IGF-binding proteins 1–6 and the localization of their gene products in normal and polycystic ovary syndrome ovaries Journal of Clinical Endocrinology and Metabolism 79 1994 1488 1496
24. Erickson GF Garzo G Magoffin D Insulin-like growth factor-I regulates aromatase activity in human granulosa and granulosa luteal cells Journal of Clinical Endocrinology and Metabolism 69 1989 716 724
25. Erickson GF Magoffin DA Dyer CA Hofeditz C The ovarian androgen producing cells: a review of structure-function relationships Endocrine Reviews 6 1985 371 399
26. Erickson GF Magoffin DA Cragun RJ The effect of insulin and insulin-like growth factor-I (IGF-I) and IGF-II on estradiol production by granulosa cells of normal and polycystic varies Journal of Clinical Endocrinology and Metabolism 70 1990 894 902
27. Erickson GF Magoffin DA Gabriel Garzo V Granulosa cells of normal and polycystic ovaries: are they normal or abnormal? Human Reproduction 7 1992 293 299
28. Fauser CJM Pache TD Lamberts SWJ Serum bioactive and immunoreactive luteinising hormone and follicle stimulating hormone levels in women with cycle abnormalities, with or without polycystic ovarian disease Journal of Clinical Endocrinology and Metabolism 73 1991 811 817
29. Ferriman D Purdie A The inheritance of PCO and possible relationship to premature balding Clinical Endocrinology 11 1979 291 300
30. Franks S Polycystic ovary syndrome: a changing perspective (review) Clinical Endocrinology 31 1989 87 120
31. Franks S Commentary; the ubiquitous polycystic ovary Journal of Endocrinology 129 1991 317 319
32. Franks S Polycystic ovary syndrome New England Journal of Medicine 333 1996 853 861
33. Franks S Adams J Mason H Polson D Ovulatory disorders in women with polycystic ovary syndrome Clinics in Obstetrics and Gynaecology 12 1989 605 632
34. Garzo VG Dorrington JH Aromatase activity in human granulosa cells during follicular development and the modulation by follicle stimulating hormone and by insulin American Journal of Obstetrics and Gynecology 148 1984 657 662
35. Geisthovel F Moretti-Rojas IM Asch RH Rojas FJ Expression of insulin-like growth factor II (IGF-II) messenger ribonucleic acid (mRNA) but not IGF-I mRNA in human preovulatory granulosa cells Human Reproduction 4 1989 899 902
36. Gharani N Waterworth D Williamson R Franks S 5 prime polymorphism of the CYP17 gene is not associated with the serum testosterone levels in women with polycystic ovaries Journal of Clinical Endocrinology and Metabolism 81 1997 1474
37. Gilling-Smith C Willis DS Mason HD Franks S Effects of insulin and insulin-like growth factors on androstenedione production by human theca cells Journal of Endocrinology 139 1993 OC35
38. Gilling-Smith C Willis DS Beard RW Hypersecretion of androstenedione by isolated thecal cells from polycystic ovaries Journal of Clinical Endocrinology and Metabolism 79 1994 1158 1165
39. Giudice L Insulin-like growth factors and ovarian follicular development Endocrine Reviews 13 1992 641 669
40. Giudice LC Farrell EM Pham H Insulin-like growth factor binding proteins in maternal serum throughout gestation and in the puerperium: effects of a pregnancy-associated serum protease activity Journal of Clinical Endocrinology and Metabolism 71 1990 806 816
41. Goff AK Leung PCK Armstrong DT Stimulatory action of follicle-stimulating hormone and androgens on the responsiveness of rat granulosa cells to gonadotrophins in vitro Endocrinology 104 1979 1124 1129
42. Grimes R Hammond JM Proteolytic degradation of insulin-like growth factor (IGF)-binding protein-3 by porcine ovarian granulosa cells in culture: regulation by IGF-I Endocrinology 134 1994 337 343
43. Hague WM Adams J Reeders S Familial polycystic ovaries: a genetic disease Clinical Endocrinology 29 1988 593 606
44. Hamori M Blum WF Torok A Insulin-like growth factors and their binding proteins in human follicular fluid Human Reproduction 6 1991 313 318
45. Hernandez ER Resnick CE Svoboda ME Somatomedin-C/insulin-like growth factor-I (Sm-C/IGF-I) as an enhancer of androgen biosynthesis by cultured rat ovarian cells Endocrinology 122 1988 1603 1612
46. Hernandez ER Resnick CE Holtzclaw WD Insulin as a regulator of androgen biosynthesis by cultured rat ovarian cells: cellular mechanisms underlying physiological and pharmacological actions Endocrinology 122 1988 2034 2043
47. Hillier SG Ross GT Effects of exogenous testosterone on ovarian weight, follicular morphology and intra-ovarian progesterone in estrogen-primed, hypophysectomised immature female rats Biology of Reproduction 20 1979 261 268
48. Hull MG Epidemiology of infertility and polycystic ovarian disease; endocrinological and demographic studies Gynaecological Endocrinology 1 1987 235 245
49. Khan CR Flier JS Bar RS The syndromes of insulin resistance and acanthosis nigricans New England Journal of Medicine 294 1976 739 745
50. Kiddy DS Hamilton-Fairley D Bush A Improvement in endocrine and ovarian function during dietary treatment of obese women with polycystic ovary syndrome Clinical Endocrinology 36 1992 105 111
51. Kirschner MA Bardin W Androgen production and metabolism in normal and virilised women Metabolism 21 1972 667 688
52. Kudlow JE Kobrin MS Purchio AF Ovarian TGFα gene expression: immunochemical localisation to the theca interstitial cells Endocrinology 121 1987 1577 1579
53. Lamson G Guidice LC Rosenfeld RG A simple assay for proteolysis of IGFBP-3 Journal of Clinical Endocrinology and Metabolism 72 1991 1391 1393
54. Lanthier A Sandor T In vitro production of androgenic steroids by human normal and ‘Stein-Leventhal-type’ ovarian slices Metabolism 9 1960 861 864
55. Lieberman S Are estradiol producing cells incompletely endowed? A chronicle of the emergence of certitude from conjecture Current Opinions in Gynaecologic Obstetric Investigations 41 1996 147 172
56. Magoffin DA Kurtz KM Erickson GF Insulin-like growth factor-I selectively stimulates cholesterol side-chain cleavage expression in ovarian theca interstitial cells Molecular Endocrinology 4 1990 489 496
57. Mahesh VB Greenblatt RB Steroid secretions of the normal and polycystic ovary Recent Progress in Hormone Research 20 1964 341 394
58. Marquart H Hunkapillar MW Hood LE Todaro GJ Rat transforming growth factor type 1: structure and relation to epidermal growth factor Science 223 1984 1079 1083
59. (supplement) Mason HD Franks S Androstenedione accumulation in human granulosa cell cultures from normal and polycystic ovaries Journal of Endocrinology 132 1992 308
60. Mason HD Margara R Winston RML Inhibition of oestradiol production by epidermal growth factor in human granulosa cells of normal and polycystic ovaries Clinical Endocrinology 33 1990 511 517
61. Mason HD Willis DS Seppalla M Franks S Inhibitory effects of insulin-like growth factor binding proteins on steroidogenesis by human granulosa cells in culture Molecular and Cellular Endocrinology 89 1992 R1 R4
62. Mason HD Margara R Winston RML Insulin-like growth factor-I (IGF-I) inhibits production of IGF-binding protein-I while stimulating estradiol secretion in granulosa cells from normal and polycystic human ovaries Journal of Clinical Endocrinology and Metabolism 76 1993 1275 1279
63. Mason HD Willis DS Holly JMP Franks S Insulin preincubation enhances insulin-like growth factor-II (IGF-II) action on steroidogenesis in human granulosa cells Journal of Clinical Endocrinology and Metabolism 78 1994 1265 1267
64. Mason HD Willis DS Beard RW Estradiol production by granulosa cells of normal and polycystic ovaries (PCO): relationship to menstrual-cycle history and to concentrations of gonadotrophins and sex steroids in follicular fluid Journal of Clinical Endocrinology and Metabolism 79 1994 1355 1360
65. Mason HD Carr L Leake R Franks S Production of transforming growth factor α by normal and polycystic ovaries Journal of Clinical Endocrinology and Metabolism 80 1995 2053 2056
66. Mason HD Davies SC Franks S Holly JMP Insulin-like growth factor I and II (IGF I and II), IGF binding proteins and IGFBP proteases are produced by normal and polycystic human ovaries Journal of Clinical Endocrinology and Metabolism 81 1996 206 213
67. McAllister JM Kerin JF Trant JM Regulation of cholesterol side chain cleavage and 17 alpha-hydroxylase/lyase activities in proliferating human theca interna cells in long-term monolayer culture Endocrinology 125 1989 1959 1966
68. McNatty KP Moore-Smith D Makris A The intra-ovarian sites of androgen and oestrogen formation in women with normal and hyperandrogenic ovaries as judged by in vitro experiments Journal of Clinical Endocrinology and Metabolism 50 1980 755 763
69. Miller WL Molecular biology of steroid hormone synthesis Endocrine Reviews 9 1988 295 318
70. Nahum R Thong KJ Hillier SG Metabolic regulation of androgen production by human thecal cells in vitro Human Reproduction 10 1995 75 81
71. Owens OJ Stewart C Leake RE Growth factors in ovarian cancer British Journal of Cancer 64 1991 1177 1181
72. Payne RW Hellbaum AA Owens JN Jr The effects of androgens on the ovaries and uterus of the estrogen-treated hypophysectomised immature rat Endocrinology 59 1956 306 316
73. Peiris AN Aiman EJ Drucker The relative contributions of hepatic and peripheral tissues to insulin resistance in hyperandrogenic women Journal of Clinical Endocrinology and Metabolism 68 1989 715 720
74. Polson DW Adams J Wadsworth J Franks S Polycystic ovaries—a common finding in normal women Lancet i 1988 870 872
75. Polson DW Reed MJ Franks S Serum 11-hydroxyandrostenedione as an indicator of the source of excess androgen production in women with polycystic ovaries Journal of Clinical Endocrinology and Metabolism 66 1988 946 950
76. Robinson S Kiddy DS Gelding SV The relationship of insulin insensitivity to menstrual pattern in women with hyperandrogenism and polycystic ovaries Clinical Endocrinology 39 1993 351 355
77. Rosenfield RL Barnes RB Cara JF Lucky AW Dysregulation of cytochrome P450c17α as the cause of polycystic ovarian syndrome Fertility and Sterility 53 1990 785 791
78. San Roman GA Magoffin DA Insulin-like growth factor binding proteins in ovarian follicles from women with polycystic ovarian disease: cellular source and levels in follicular fluid Journal of Clinical Endocrinology and Metabolism 75 1992 1010 1015
79. San Roman GA Magoffin DA Insulin-like growth factor binding proteins in healthy and atretic follicles during natural menstrual cycles Journal of Clinical Endocrinology and Metabolism 76 1993 625 632
80. Short RV Steroids in the follicular fluid and the corpus luteum of the mare. A ‘two-cell theory of ovarian steroid biosynthesis Journal of Endocrinology 24 1962 59 63
81. Short RV London DR Defective biosynthesis of ovarian steroids in the Stein-Leventhal syndrome British Medical Journal 1 1961 1724 1727
82. Stein IF Leventhal ML Amenorrhoea associated with bilateral polycystic ovaries American Journal of Obstetrics and Gynecology 29 1935 181 191
83. Ui M Shimonaka M Shimasaki S Ling N An insulin-like growth factor binding protein (IGFBP) in ovarian follicular fluid blocks follicle stimulating hormone-stimulated steroid production by ovarian granulosa cells Endocrinology 125 1989 912 916
84. Vermeulin A The androgens Gray CH James VHT Hormones in Blood vol. 3 1979 Academic Press London 355 416
85. Voutilainen R Miller W Coordinate trophic hormone regulation of mRNAs for insulin-like growth factor II and cholesterol side chain-cleavage enzyme, P450scc, in human steroidogenic tissues Proceedings of the National Academy of Sciences 84 1987 1590 1594
86. Voutillainen R Franks S Mason HD Martikainen H Expression of insulin-like growth factor (IGF), IGF binding protein and IGF receptor mRNAs in thecal tissue of normal and polycystic ovaries Journal of Clinical Endocrinology and Metabolism 81 1996 1003 1008
87. abstract 1224 White DM Mason HD Franks S 24-hour pattern of LH secretion in ovulatory women with polycystic ovaries: evidence for normal hypothalamic regulation of LH Meeting of the Endocrine Society Washington 1991 1991
88. White DM Leigh A Wilson C Gonadotrophin and gonadal steroid response to a single dose of a long-acting agonist of gonadotrophin-releasing hormone in ovulatory and anovulatory women with polycystic ovary syndrome Clinical Endocrinology 42 1995 475 481
89. Willis DS Mason HD Franks S Insulin, insulin-like growth factors and anovulation in polycystic ovary syndrome Le Roith The Role of Insulin-Like Growth Factors in Ovarian Physiology Proceedings of Serono Symposia (USA) Montpellier, France 1996
90. Willis DS Mason HD Gilling-Smith Modulation by insulin of follicle stimulating hormone and luteinizing hormone actions in human granulosa cells of normal and polycystic ovaries Journal of Clinical Endocrinology and Metabolism 81 1996 302 309
91. Willis DS Mason HD Watson H Characterisation of the LH response in granulosa cells from individual follicles from normal or polycystic ovaries 10th International Congress of Endocrinology San Francisco OC 26-1 1996
92. Wilson EA Erickson G Zarutski P Endocrine studies of normal and polycystic ovarian tissue in vitro American Journal of Obstetrics and Gynecology 134 1979 56 63
93. Yen SCC The polycystic ovary syndrome Clinical Endocrinology 12 1980 177 207
94. Yong EL Baird DT Yates R Hormonal regulation of the growth and steroidogenic function of human granulosa cells Journal of Clinical Endocrinology and Metabolism 74 1992 842 849
95. Yong EL Baird DT Yates R Mediation of gonadotrophin-stimulated growth and differentiation of human granulosa cells by adenosine-3′,5′-monophosphate: one molecule, two messages Clinical Endocrinology 37 1992 51 58