High serum levels of vascular endothelial growth factor in patients with human hepatocellular carcinoma

Hepatology Research

Volumn 7, Issue 1, 1997, Pages 13-18

  Ohira, Yoko ^a   Miura, Hideo ^a   Tojo, Jun ^b   Ohira, Hiromasa ^b   Kuroda, Masahito ^b   Obara, Katsutoshi ^b   Kasukawa, Reiji ^b  

^a Prefectural Hospitals Bureau   (Japan)

^b FUKUSHIMA MEDICAL UNIVERSITY   (Japan)

Author keywords

Carcinoma; Endothelial; Hepatocellular

Indexed keywords

VASCULOTROPIN;

ANGIOGENESIS; ARTICLE; BLOOD LEVEL; CHRONIC HEPATITIS; CLINICAL ARTICLE; CONTROLLED STUDY; DIAGNOSTIC VALUE; HUMAN; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; NEOVASCULARIZATION (PATHOLOGY); PRIORITY JOURNAL; TUMOR BLOOD FLOW;

EID: 0030742669     PISSN: 09284346     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0928-4346(97)00366-6     Document Type: Article

References (12)

1. Ferrara N, Houch Ka, Jakeman LB, Leung DW. Molecular and biological properties of the vascular endothelial growth factor family of proteins. Endocr Rev 1992; 138: 18-32.
2. Kondo S, Asano M, Suzuki H. Significance of vascular endothelial growth factor/vascular permeability factor for solid tumor growth and its inhibition by the antibody. Biochem Biophys Res Commun 1993; 194: 1234-1241.
3. Brown LF, Berse B, Jackman RW, Tognazzi K, Manseau EJ, Senger DR, Dvorsk HF. Expression of vascular permeability factor (vascular endothelia growth factor) and its receptors in adenocarcnomas of the gastrointestinal tract. Cancer Res 1993; 53: 4727-4735.
4. Plate KH, Breier G, Weich HA, Risau W. Vascular endothelia growth factor is a potential tumor angiogenesis factor in human gliomas in vivo. Nature 1992; 359: 854-84.
5. Brown LF, Berse B, Jackman RW, Tognazzi K, Manseau EJ, Dvorak HF, Senger DR. Increased expression of vascular permeability factor (vascular endothelia growth factor) and its receptors in kidney and bladder carcinoma. Am J Pathol 1993; 143: 1255-1262.
6. Suzuki K, Hayashi N, Miyamoto Y, Yamamoto Y, Yamamoto M, Ohkawa K, Ito Y, Sasaki Y, Yamaguchi Y, Nakase H, Noda K, Enomoto N, Arai K, Yamada Y, Yoshihara H, Tujimura T, Kawano K, Yoshikawa K, Kamada T. Expression of vascular permeability factor/vascular endothelial growth factor in human hepatocellular carcinoma. Cancer Res 1996; 56: 3004-3009.
7. Kondo S, Asano M, Matsuo K, Ohmori I, Suzuki H. Vascular endothelia growth factor/vascular permeability factor is detectable in the sera of tumor-bearing mice and cancer patients. Biochem Biophys Acta 1994; 1221: 211-214.
8. Mise M, Arii S, Higashituji H, Furutani M, Niwano M, Harada T, Ishigami S, Toda Y, Nakayama H, Fukumoto M, Fujita J, Imamura M. Clinical significance of vascular endothelia growth factor and basic fibroblast growth factor gene expression in liver tumor. Hepatology 1996; 23: 455-464.
9. Yamane A, Seetharam L, Yamaguchi S, Gotoh N, Takahashi T, Neufeld G, Shibuya M. A new communication system between hepatocytes and sinusoidal endothelial cells in liver through vascular endothelia growth factor and Fit tyrosine kinase receptor family (Fit-1 and KDR/Flk-1). Oncogene 1994; 9: 2683-2690.
10. Folkman J. What is the evidence that tumors are angiogenesis dependent? J Natl Cancer Inst 1990; 82: 4-6.
11. Folkman J, Shing Y. Angiogenesis. J Biol Chem 1992; 267: 10931-10934.
12. Shweiki D, Itin A, Soffer D, Kerhet E. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature (Lond.) 1992; 359: 843-845.