Characteristics of human EBV-specific cytotoxic T lymphocytes utilized for adoptive immunotherapy of EBV-induced lymphoproliferations in xenografted SCID mice

Annals of Oncology

Volumn 8, Issue SUPPL. 2, 1997, Pages

  Lacerda, J F ^a,b,c   O'Reilly, R J ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b UNIVERSITY OF LISBON   (Portugal)

^c HOSPITAL DE SANTA MARIA   (Portugal)

Author keywords

Bone marrow transplantation; Cytotoxic T lymphocytes; Epstein Barr virus; Immunotherapy; Lymphoproliferative disorders; Severe combined immune deficiency mice

Indexed keywords

CD11B ANTIGEN; CD16 ANTIGEN; CD18 ANTIGEN; CD28 ANTIGEN; CD3 ANTIGEN; CD4 ANTIGEN; CD45 ANTIGEN; CD56 ANTIGEN; CD8 ANTIGEN; GLYCOPROTEIN P 15095; HERMES ANTIGEN; HLA ANTIGEN; HLA ANTIGEN CLASS 1; HLA ANTIGEN CLASS 2; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 2; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 3; MONOCLONAL ANTIBODY; T LYMPHOCYTE RECEPTOR; THYMIDINE;

ADOPTIVE IMMUNOTHERAPY; ANIMAL CELL; ANIMAL MODEL; BONE MARROW TRANSPLANTATION; CONFERENCE PAPER; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; CYTOTOXICITY; EPSTEIN BARR VIRUS; HUMAN; HUMAN CELL; IMMUNOPHENOTYPING; LYMPHOPROLIFERATIVE DISEASE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SCID MOUSE; XENOGRAFT;

EID: 0030742305     PISSN: 09237534     EISSN: None     Source Type: Journal    
DOI: 10.1093/annonc/8.suppl_2.S137     Document Type: Conference Paper

References (10)

1. Rickinson AB, Moss DJ, Wallace LE et al. Long-term cell-mediated immunity to Epstein-Barr virus. Cancer Res 1981; 41: 4216-21.
2. Cohen JI. Epstein-Barr virus lymphoproliferative disease associated with acquired immunodeficiency. Medicine 1991; 70: 137-60.
3. Shapiro RS, MaClain K, Frizzera G et al. Epstein-Barr virus associated B-cell lymphoproliferative disorders following bone marrow transplantation. Blood 1988; 71: 1234-43.
4. Zutter MM, Martin PJ, Sale GE et al. Epstein-Barr virus lymphoproliferation after bone marrow transplantation. Blood 1988; 72: 520-9.
5. Papadopoulos EB, Ladanyi M, Emanuel D et al. Infusions of donor leukocytes to treat Epstein-Barr virus-associated lymphoproliferative disorders complicating allogeneic bone marrow transplantation. N Engl J Med 1994; 330: 1185-91.
6. Lacerda JF, Ladanyi M, Jagiello C et al. Administration of rabbit anti-asialo GM1 antiserum facilitates the development of human EBV-induced lymphoproliferations in xenografted C.B-17 scid/scid mice. Transplantation 1996; 61: 492-7.
7. Lacerda JF, Ladanyi M, Louie DC et al. Human Epstein-Barr virus (EBV)-specific cytotoxic T lymphocytes home preferentially to and induce selective regressions of autologous EBV-induced lymphoproliferations in xenografted C.B-17 scid/scid mice. J Exp Med 1996; 183: 1215-28.
8. Bourgault I, Gomez A, Gomard E et al. Limiting-dilution analysis of the HLA restriction of anti-Epstein-Barr virus-specific cytolytic T lymphocytes. Clin Exp Immunol 1991; 84: 501-7.
9. Lucas K, Small T. Heller G et al. The development of Epstein-Barr virus specific cellular immunity following allogeneic marrow transplantation. Blood 1996; 87: 2594-603.
10. Rooney CM, Smith CA, Ng CYC et al. Use of gene-modified virus-specific T lymphocytes to control Epstein-Barr-virus-related lymphoproliferation. Lancet 1995: 345: 9-13.