Upregulation and co-localization of connexin43 and cellular adhesion molecules in inflammatory renal disease

Journal of Pathology

Volumn 182, Issue 4, 1997, Pages 373-379

  Hillis, Graham S ^a,b   Duthie, Lesley A ^a   Brown, Paul A J ^a   Simpson, John G ^a   Macleod, Alison M ^a   Haites, Neva E ^a  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

^b ROYAL INFIRMARY OF EDINBURGH   (United Kingdom)

Author keywords

adhesion molecule; connexin; E selectin; glomerulonephritis; ICAM 1; immunohistochemistry; kidney; VCAM 1

Indexed keywords

CELL ADHESION MOLECULE; CONNEXIN 43; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1;

ADULT; AGED; ARTICLE; CELL FUNCTION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GLOMERULONEPHRITIS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KIDNEY BIOPSY; MALE; PRIORITY JOURNAL;

ADULT; AGED; CELL ADHESION MOLECULES; CONNEXIN 43; E-SELECTIN; FEMALE; GLOMERULONEPHRITIS; HUMANS; IMMUNOHISTOCHEMISTRY; INTERCELLULAR ADHESION MOLECULE-1; KIDNEY; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALE; MIDDLE AGED; VASCULAR CELL ADHESION MOLECULE-1; WEGENER GRANULOMATOSIS;

EID: 0030742168     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9896(199708)182:4<373::AID-PATH858>3.0.CO;2-B     Document Type: Article

References (29)

1. White TW, Bruzzone R, Paul DL. The connexin family of intercellular channel forming proteins. Kidney Int 1995; 48: 1148-1157.
2. Beyer EC, Paul DL, Goodenough DA. Connexin family of gap junction proteins. J Membn Biol 1990; 116: 187-194.
3. Beyer EC, Paul DL, Goodenough DA. Connexin 43: a protein from rat heart homologous to a gap junction protein from liver. J Cell Biol 1987; 105: 2621-2629.
4. Evans WH. Assembly of gap junction intercellular communication channels. Biochem Soc Trans 1994; 22: 788-792.
5. Davis LM, Kanter HL, Beyer EC, Saffitz JE. Distinct gap junction protein phenotypes in cardiac tissues with disparate conduction properties. J Am Coll Cardiol 1994; 24: 1124-1132.
6. Bennet MVL. Connexins in disease. Nature 1994; 368: 18-19.
7. Bruzzone R, Meda P. The gap junction: a channel for multiple functions? Eur Clin Invest 1988; 18: 444-453.
8. Warner AE. Gap junctions in development: a perspective. Semin Cell Biol 1992; 3: 81-91.
9. Lowenstein WR, Rose B. The cell-cell channel in the control of growth. Semin Cell Biol 1992; 3: 59-79.
10. Ruch RJ. The role of gap junctional intercellular communication in neoplasia. Ann Clin Lab Sci 1994; 24: 216-231.
11. Krutovskikh VA, Mesnil M, Mazzoleni G, Yamasaki H. Inhibition of a rat liver gap junction intercellular communication by tumour-promoting agents in vivo. Lab Invest 1995; 72: 571-577.
12. Hillis GS, Duthie LA, Mlynski RA, et al. Connexin 43 expression in human kidney and cultured renal cells. Nephron (in press).
13. Polacek D, Lal R, Volin MV, Davies PF. Gap junctional communication between vascular cells: induction of connexin43 messenger RNA in macrophage foam cells of atherosclerotic lesions. Am J Pathol 1993; 142: 593-606.
14. Spray DC, Fujita M, Saez JC, et al. Proteoglycans and glycosaminoglycans induce gap junction synthesis and function in primary liver cultures. J Cell Biol 1987; 105: 541-551.
15. Keane RW, Mehta PP, Rose B, Honig LS, Lowenstein WR, Rutishauser U. Neural differentiation, NCAM-mediated adhesion and gap junctional communication in ectoderm: a study in vitro. J Cell Biol 1988; 106: 1307-1329.
16. Mege R-M, Matsuzaki F, Gallin WJ, Goldberg JI, Cunningham BA, Edelman GM. Construction of epithelioid sheets by transfection of mouse sarcoma cells with cDNAs for chicken cell adhesion molecules. Proc Natl Acad Sci USA 1988; 85: 7274-7278.
17. 2+ in mouse epidermal cells is controlled by E-cadherin. J Cell Biol 1991; 114: 545-555.
18. Cordell JL, Falini B, Erber WN, et al. Immunoenzymatic labelling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes). J Histochem Cytochem 1984; 32: 219-229.
19. Pall AA, Howie AJ, Adu D, et al. Glomerular vascular cell adhesion molecule-1 expression in renal vasculitis. J Clin Pathol 1996; 49: 238-242.
20. Bruijn JA, Dinklo JCM. Distinct patterns of expression of intercellular adhesion molecule-1, vascular cell adhesion molecule-1, and endothelialleukocyte adhesion molecule-1 in renal disease. Lab Invest 1993; 69: 329-335.
21. Roy-Chaudhury P, Wu B, King G, et al. Adhesion molecule interactions in human glomerulonephritis: importance of the tubulointerstitium. Kidney Int 1996; 49: 127-134.
22. Muller GA, Markovic-Lipkovski J, Muller CA. Intercellular adhesion molecule-1 expression in human kidneys with glomerulonephritis. Clin Nephrol 1991; 36: 203-208.
23. Lhotta K, Neumayer HP, Joannidis M, Geissler K, Konig P. Renal expression of intercellular adhesion molecule-1 in different forms of glomerulonephrits. Clin Sci 1991; 81: 477-481.
24. Hillis GS, Roy-Chaudhury P, Duthie L, et al. Changes in VLA integrin expression in mesangioproliferative glomerulonephritis. J Am Soc Nephrol 1995; 6: 896 (Abstract).
25. Patey N, Lesavre P, Halbwachs-Mecarelli L, Noel LH. Adhesion molecules in human crescentic glomerulonephritis. J Pathol 1996; 179: 414-420.
26. Brady HR. Leukocyte adhesion molecules and kidney diseases. Kidney Int 1994; 45: 1285-1300.
27. Dal Canton A. Adhesion molecules in renal disease. Kidney Int 1995; 48: 1687-1696.
28. Seron D, Cameron JS, Haskard DO. Expression of VCAM-1 in the normal and diseased kidney. Nephrol Dial Transplant 1991; 6: 917-922.
29. Beyer EC, Steinberg TH. Evidence that the gap junction protein connexin-43 is the ATP-induced pore of mouse macrophages. J Biol Chem 1991; 266: 7971-7974.