Nucleic acid immunization of chimpanzees as a prophylactic/immunotherapeutic vaccination model for HIV-1: Prelude to a clinical trial

Vaccine

Volumn 15, Issue 8, 1997, Pages 927-930

  Ugen, Kenneth E ^a   Boyer, Jean D ^b   Wang, Bin ^b,c   Bagarazzi, Mark ^b   Javadian, Ali ^d   Frost, Pat ^d   Merva, Michael M ^b   Agadjanyan, Michael G ^b   Nyland, Susan ^a   Williams, William V ^b   Coney, Leslie ^c,e   Ciccarelli, Richard ^c,e   Weiner, David B ^b,c  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c Inst Biotech and Adv Molec Med   (United States)

^d White Sands Research Center   (United States)

^e Apollon Inc   (United States)

Author keywords

Cellular immunity; Chimpanzee; Clinical trial; DNA plasmid; Envelope glycoprotein; HIV 1; Humoral immunity; Nucleic acid vaccination

Indexed keywords

DNA VACCINE; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; PLASMID DNA; VIRUS ENVELOPE PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY RESPONSE; CHIMPANZEE; CONFERENCE PAPER; CYTOTOXIC T LYMPHOCYTE; DOSE RESPONSE; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INTRAMUSCULAR DRUG ADMINISTRATION; NONHUMAN; PRIORITY JOURNAL; VIRUS ENVELOPE; VIRUS GENE;

AIDS VACCINES; AMINO ACID SEQUENCE; ANIMALS; DISEASE MODELS, ANIMAL; DNA, VIRAL; DRUG EVALUATION, PRECLINICAL; HIV ANTIBODIES; HIV INFECTIONS; HIV-1; MOLECULAR SEQUENCE DATA; PAN TROGLODYTES; T-LYMPHOCYTES, CYTOTOXIC; VACCINATION; VACCINES, DNA;

EID: 0030741990     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0264-410X(96)00254-X     Document Type: Conference Paper

References (10)

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