Effect of growth hormone therapy on bone metabolism of growth hormone deficient children

European Journal of Pediatrics

Volumn 156, Issue 8, 1997, Pages 592-596

  Stamoyannou, L ^b   Karachaliou, F ^b   Gioureli, E ^b   Voskaki, E ^c   Mengreli, C ^c   Bartsocas, C S ^a,b   Koutselinis, A ^b  

^a P and A Kyriakou Children's Hosp ^*  (Greece)

^b UNIVERSITY OF ATHENS   (Greece)

^c Institute of Child Health   (Greece)

Author keywords

1,25(OH)2vitD; Bone; Growth hormone; Osteocalcin; Parathormone

Indexed keywords

25 HYDROXYVITAMIN D; ALKALINE PHOSPHATASE; CALCITRIOL; CALCIUM; HUMAN GROWTH HORMONE; INSULIN; LEVODOPA; OSTEOCALCIN; PARATHYROID HORMONE; PHOSPHATE; SOMATOMEDIN C;

BLOOD LEVEL; BONE; BONE METABOLISM; CHILD; CLINICAL ARTICLE; COLORIMETRY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GROWTH HORMONE DEFICIENCY; HUMAN; IMMUNORADIOMETRIC ASSAY; MALE; MINERAL METABOLISM; PREDICTION; PRIORITY JOURNAL; PROVOCATION TEST; RADIORECEPTOR ASSAY; REVIEW; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0030741973     PISSN: 03406199     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004310050671     Document Type: Review

References (30)

1. Argente J, Heinegard D (1994) What is the clinical significance of biochemical markers of growth and hone metabolism? Acta Paediatr 406[Suppl]:99-102
2. Balducci R, Toscano V, Posquino AM, Mangiantini A, Municchi G, Armenise P, Terracina S, Prossomariti G, Boscherini B (1995) Bone turnover and bone mineral density in young adult patients with panhypopituitarism before and after long-term growth hormone therapy. Eur J Endocrinol 132:42-46
3. Bengston B-A, Eden S, Lonn L, Knist H, Stokland A, Lindstedt G, Busaeus I, Tolli J, Sjostom L, Isaksson OGP (1993) Treatment of adults with growth hormone (GH) deficiency with recombinant GH. J Clin Endocrinol Metab 76:309-317
4. Bonjour JP, Caverzasio J (1984) Phosphate transport in the kidney. Rev Physiol Biochem Pharmacol 100:162-166
5. Crofton PM, Stirling HF, Kelnar CJH (1995) Bone alkaline phosphatase and height velocity in short normal children undergoing growth-promoting treatments:Longitudinal study. Clin Chem 41:672-678
6. Crofton PM, Stirling HF, Schonau E, Ahmed SF, Wallace WHB, Wade JC, Magowan R, Shrivastava A, Lyon AJ, McIntosh N, Kelnar CJH (1996) Biochemical markers of bone turnover Horm Res 45[Suppl 1]:55-58
7. Caverzasio J, Bonjour JP (1988) Influence of recombinant IGFI (somatomedin C) on sodium dependent phosphate transport in cultured renal epithelium. Prog Clin Biol Res 252:385-386
8. 3. Endocrinology 127:453-459
9. Edelstein M, Charman DEM, Lawson E, Kodicek E (1974) Competitive protein-binding assay for 25-hydroxycholecalciferol. Clin Sci Molec Med 46:231-239
10. 2- vitD concentration in response to dietary phosphorus deprivation in hypophysectomized rats. Calcif Tissue Int 35:100-106
11. Greenwood FC, Hunter WM, Marian VJ (1964) Growth hormone levels in children and adolescents. BMJ 1:25-28
12. Greulich WW, Pyle SI (1959) Radiographic atlas of skeletal development of the hand and wrist. 2nd edn. Stanford University Press, Stanford
13. Hammerman MR, Gavin WJR (1986) Binding of IGF-I and IGF-I stimulated phosphorylation in canine renal basolateral membranes. Am J Physiol 251:E32
14. Henneman PH, Forbes AP, Modawer M, Dempsey EF, Carrol EL (1960) Effects of human growth hormone in man. J Clin Invest 39:1223-1238
15. Johansen JS, Jensen SB, Riss BJ, Rasmussen L, Zachmann M, Christiansen C (1990) Serum hone Gla protein: a potential marker of growth hormone (GH) deficiency and the response to GH therapy. J Clin Endocrinol Metab 71:122-126
16. Kiebzak GM, Saktor B (1986) Effect of age on renal conservation of phosphate in the rat. Am J Physiol 251:F399
17. Kubo T , Tanaka H, Inoue M, Kanzaki S, Seino Y (1995) Serum levels of carboxyterminal propeptide of type I procollagen and pyridinoline telopeptide of type I collagen in normal children and children with growth hormone (GH) deficiency during GH therapy. Bone 17:397-401
18. Liang CI, Barnes J, Balakir R, Cheng L, Saktor B (1982) In vivo stimulation of phosphate uptake in isolated chick renal cells by dihydroxycholecalciferol. Proc Natl Acad Sci USA 79:3532
19. Marcus R, Butterfield G, Holloway L, Gilliland L, Baylink DJ, Hintz RL, Sherman BM (1990) Effect of short term administration of recombinant human growth hormone to elderly people. J Clin Endocrinol Metab 70:519-525
20. Nielsen HK, Jorgensen JO, Brixen K, Maller N, Charles P, Christensen JS (1991) 24 h profile of serum osteocalcin in growth hormone (GH) deficient patients with and without GH treatment. Growth Regul 1:153-159
21. Nishiyama S, Ikuta M, Nakamura T, Tomoeda S, Matsuda I (1992) Renal handling of phosphate can predict height velocity during growth hormone therapy for short children. J Clin Endocrinol Metab 74(4):906-909
22. Prader A, Zachmann M, Poley JR, Illig R (1968) The metabolic effeet of a small uniform dose of human growth hormone in hypopituitary dwarfs and in control children. Acta Endocrinol (Copenhag) 57:115-128
23. Saggesse G, Baroncelli GI, Bertelloni S, Cinquanta L, Di Nero G (1993) Effects of long-term treatment with growth hormone on bone and mineral metabolism in children with growth hormone deficiency. J Pediatr 122:37-45
24. Saggese G, Baroncelli GI, Federico G, Berteloni S (1995) Effects of growth hormone on phospho calcium homeostasis and bone metabolism. Horm Res 44[Suppl 3]:55-63
25. Sartorio A, Conti A, Monzani M (1993) New markers of bone and collagen turnover in children and adults with growth hormone deficiency. Postgrad Med J 69:846-850
26. Seino Y, Kanzaki S, Kubo T, Hibi I, Tanaka T, Suwa S, Tachiboma K, Okumo A, Niimi H, Tsuchiya Y (1994) Serum level of intact molecular osteocalcin in children with growth hormone (GH) deficiency during GH therapy:an early predictor of GH therapy. Nippon Naibunpi Gakkai Zasshi 70:1063-1074
27. Spanos E, Barrett D, MacIntyre I, Pike JW, Safilian E, Haussler MR (1978) Effect of growth hormone in vitamin D metabolism. Nature 273:246-247
28. Stark H, Eisenstein B, Tieder M, Rachmel A, Alpert G (1986) Direct measurement of TP/GER: A simple and reliable parameter of renal phosphate handling. Nephron 44:125-128
29. Tomoeda S, Nishiyama S, Nakamura T, Matsuda I (1994) Can renal handling of phosphate predict response to growth hormone therapy in normal variant short children by short-term treatment? Acta Paediatr 83:36-40
30. Valk NK, Erdtsieck RJ, Algra D, Lamberts SWJ, Pols HAP (1995) Combined treatment of growth hormone and the biphosphonate pamidronate versus treatment with GH alone, in GH-deficient adults: the effect on renal phosphate handling, bone turnover and bone mineral mass. Clin Endocrinol 43:317-324