Improvement of buccal delivery of morphine using the prodrug approach

International Journal of Pharmaceutics

Volumn 154, Issue 2, 1997, Pages 157-165

  Christrup, Lona Louring ^a   Christensen, Christian Broen ^b   Friis, Gitte Juel ^a   Jørgensen, Aksel ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Buccal absorption Prodrug; Ester; In vitro permeation; Morphine; Ussing chamber

Indexed keywords

MORPHINE; MORPHINE 3 HEXANOATE; MORPHINE 3 OCTANOATE; MORPHINE 3 PROPIONATE; MORPHINE DERIVATIVE; PRODRUG; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CHEEK MUCOSA; CONTROLLED STUDY; DRUG DEGRADATION; DRUG HYDROLYSIS; DRUG PENETRATION; DRUG STABILITY; DRUG TISSUE LEVEL; HUMAN; MALE; NONHUMAN; NORMAL HUMAN; PHARMACOKINETICS; PRIORITY JOURNAL; RAT; SALIVA; SWINE;

EID: 0030741868     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(97)00128-2     Document Type: Article

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