-
1
-
-
0025805934
-
Deletion of the entire cytochrome P450 CYP2D6 gene as a cause of impaired drug metabolism in poor metabolizers of the debrisoquine/sparteine polymorphism
-
Gaedigk A, Blum M, Gaedigk R, Eichelbaum M, Meyer UA. Deletion of the entire cytochrome P450 CYP2D6 gene as a cause of impaired drug metabolism in poor metabolizers of the debrisoquine/sparteine polymorphism. Am J Hum Genet 1991;48:943-50.
-
(1991)
Am J Hum Genet
, vol.48
, pp. 943-950
-
-
Gaedigk, A.1
Blum, M.2
Gaedigk, R.3
Eichelbaum, M.4
Meyer, U.A.5
-
2
-
-
0017695082
-
Polymorphic hydroxylation of debrisoquine in man
-
Mahgoub A, Idle JR, Dring LG, Lancaster R, Smith RL. Polymorphic hydroxylation of debrisoquine in man. Lancet 1977;1:584-6.
-
(1977)
Lancet
, vol.1
, pp. 584-586
-
-
Mahgoub, A.1
Idle, J.R.2
Dring, L.G.3
Lancaster, R.4
Smith, R.L.5
-
4
-
-
0023701452
-
Polymorphic debrisoquin hydroxylation in 757 Swedish subjects
-
Steiner E, Bertilsson L, Sawe J, Bertling I, Sjøqvist F. Polymorphic debrisoquin hydroxylation in 757 Swedish subjects. Clin Pharmacol Ther 1988;44:431-5.
-
(1988)
Clin Pharmacol Ther
, vol.44
, pp. 431-435
-
-
Steiner, E.1
Bertilsson, L.2
Sawe, J.3
Bertling, I.4
Sjøqvist, F.5
-
5
-
-
34547384928
-
A 'cocktail' study design in the assessment of sparteine, mephenytoin and nifedipine metabolite distribution in a Dutch population
-
Schellens JHM. dissertatie. Leiden: Rijksuniversiteit Leiden
-
Schellens JHM, Hermans J, Breimer DD. A 'cocktail' study design in the assessment of sparteine, mephenytoin and nifedipine metabolite distribution in a Dutch population. In: Schellens JHM. Characterization of human drug oxidation in vivo. [dissertatie]. Leiden: Rijksuniversiteit Leiden, 1988.
-
(1988)
Characterization of Human Drug Oxidation in Vivo
-
-
Schellens, J.H.M.1
Hermans, J.2
Breimer, D.D.3
-
6
-
-
0023134082
-
Genetic variation in the human hepatic cytochrome P-450 system
-
Kalow W. Genetic variation in the human hepatic cytochrome P-450 system. Eur J Clin Pharmacol 1987;31:633-41.
-
(1987)
Eur J Clin Pharmacol
, vol.31
, pp. 633-641
-
-
Kalow, W.1
-
7
-
-
0025316892
-
Human cytochrome P450 isoforms. Their genetic heterogeneity and induction by omeprazole
-
Farrell GC, Murray M. Human cytochrome P450 isoforms. Their genetic heterogeneity and induction by omeprazole. Gastroenterology 1990;99:885-9.
-
(1990)
Gastroenterology
, vol.99
, pp. 885-889
-
-
Farrell, G.C.1
Murray, M.2
-
8
-
-
12644252170
-
An integrated molecular and kinetic/dynamic approach to metabolism in drug development
-
Alvan G, Balant LP, Bechtel PR, Boobis AR, Gram LF, Paintaud G, Pithan K, red. Luxemburg: Office for official publications of the European Communities
-
Breimer DD. An integrated molecular and kinetic/dynamic approach to metabolism in drug development. In: Alvan G, Balant LP, Bechtel PR, Boobis AR, Gram LF, Paintaud G, Pithan K, red. European cooperation in the field of scientific and technical research. COST B1 conference on variability and specificity in drug metabolism. Luxemburg: Office for official publications of the European Communities, 1995:3-19.
-
(1995)
European Cooperation in the Field of Scientific and Technical Research. COST B1 Conference on Variability and Specificity in Drug Metabolism
, pp. 3-19
-
-
Breimer, D.D.1
-
9
-
-
0000141385
-
Role of environmental factors in the pharmacokinetics of drugs: Considerations with respect to animal models, P-450 enzymes, and probe drugs
-
Welling PG, Balant LP. Berlijn: Springer-Verlag
-
Pelkonen O, Breimer DD. Role of environmental factors in the pharmacokinetics of drugs: considerations with respect to animal models, P-450 enzymes, and probe drugs. In: Welling PG, Balant LP. Handbook of experimental pharmacology. Vol 110. Pharmacokinetics of drugs. Berlijn: Springer-Verlag, 1994:289-332.
-
(1994)
Handbook of Experimental Pharmacology. Vol 110. Pharmacokinetics of Drugs
, vol.110
, pp. 289-332
-
-
Pelkonen, O.1
Breimer, D.D.2
-
10
-
-
0024370922
-
Influence of enzyme induction and inhibition on the oxidation of nifedipine, sparteine, mephenytoine and antipyrine in humans as assessed by a 'cocktail' study design
-
Schellens JHM, Van der Wart JHF, Brugman M, Breimer DD. Influence of enzyme induction and inhibition on the oxidation of nifedipine, sparteine, mephenytoine and antipyrine in humans as assessed by a 'cocktail' study design. J Pharmacol Exp Ther 1989;249:638-45.
-
(1989)
J Pharmacol Exp Ther
, vol.249
, pp. 638-645
-
-
Schellens, J.H.M.1
Van Der Wart, J.H.F.2
Brugman, M.3
Breimer, D.D.4
-
11
-
-
0025285552
-
A 'cocktail' strategy to assess in vivo oxidative drug metabolism in humans
-
Breimer DD, Schellens JHM. A 'cocktail' strategy to assess in vivo oxidative drug metabolism in humans. Trends Pharmacol Sci 1990;11:223-5.
-
(1990)
Trends Pharmacol Sci
, vol.11
, pp. 223-225
-
-
Breimer, D.D.1
Schellens, J.H.M.2
-
13
-
-
0026670643
-
Prediction of phenotype for acetylation and for debrisoquine hydroxylation by DNA-tests in healthy human volunteers
-
Graf T, Broly F, Hoffman F, Probst M, Meyer UA, Howald H. Prediction of phenotype for acetylation and for debrisoquine hydroxylation by DNA-tests in healthy human volunteers. Eur J Clin Pharmacol 1992;43:399-403.
-
(1992)
Eur J Clin Pharmacol
, vol.43
, pp. 399-403
-
-
Graf, T.1
Broly, F.2
Hoffman, F.3
Probst, M.4
Meyer, U.A.5
Howald, H.6
-
14
-
-
0026506140
-
Pronounced differences between native Chinese and Swedish populations in the polymorphic hydroxylations of debrisoquine and S-mephenytoin
-
Bertilsson L, Lou YQ, Du YL, Liu Y, Kuang TY, Liao XM, et al. Pronounced differences between native Chinese and Swedish populations in the polymorphic hydroxylations of debrisoquine and S-mephenytoin. Clin Pharmacol Ther 1992;51:388-97.
-
(1992)
Clin Pharmacol Ther
, vol.51
, pp. 388-397
-
-
Bertilsson, L.1
Lou, Y.Q.2
Du, Y.L.3
Liu, Y.4
Kuang, T.Y.5
Liao, X.M.6
-
16
-
-
0023681993
-
Debrisoquin oxidation polymorphism in a Spanish population
-
Benitez J, Llerena A, Cobaleda J. Debrisoquin oxidation polymorphism in a Spanish population. Clin Pharmacol Ther 1988;44:74-7.
-
(1988)
Clin Pharmacol Ther
, vol.44
, pp. 74-77
-
-
Benitez, J.1
Llerena, A.2
Cobaleda, J.3
-
17
-
-
0028174309
-
CYP2D6-related oxidation polymorphism in Italy
-
Spina E, Campo GM, Avenoso A, Caputi AP, Zuccaro P, Pacifici R, et al. CYP2D6-related oxidation polymorphism in Italy. Pharmacol Res 1994;29:281-9.
-
(1994)
Pharmacol Res
, vol.29
, pp. 281-289
-
-
Spina, E.1
Campo, G.M.2
Avenoso, A.3
Caputi, A.P.4
Zuccaro, P.5
Pacifici, R.6
-
18
-
-
0028365855
-
Genetically determined sparteine oxidation polymorphism in a Polish population
-
Orzechowska-Juzwenko K, Pawlik J, Niewinski P, Milejski P, Dembowski J, Turek J, et al. Genetically determined sparteine oxidation polymorphism in a Polish population [brief]. Eur J Clin Pharmacol 1994;46:481-3.
-
(1994)
Eur J Clin Pharmacol
, vol.46
, pp. 481-483
-
-
Orzechowska-Juzwenko, K.1
Pawlik, J.2
Niewinski, P.3
Milejski, P.4
Dembowski, J.5
Turek, J.6
-
20
-
-
0028114838
-
S-mephenytoin, sparteine and debrisoquine oxidation: Genetic polymorphisms in a Turkish population
-
Basci NE, Brøsen K, Bozkurt A, Isimer A, Sayal A, Kayaalp SO. S-mephenytoin, sparteine and debrisoquine oxidation: genetic polymorphisms in a Turkish population. Br J Clin Pharmacol 1994;38:463-5.
-
(1994)
Br J Clin Pharmacol
, vol.38
, pp. 463-465
-
-
Basci, N.E.1
Brøsen, K.2
Bozkurt, A.3
Isimer, A.4
Sayal, A.5
Kayaalp, S.O.6
-
21
-
-
0028028050
-
Debrisoquine and mephenytoin oxidation in Sinhalese: A population study
-
Weerasuriya K, Jayakody RL, Smith CAD, Wolf CR, Tucker GT, Lennard MS. Debrisoquine and mephenytoin oxidation in Sinhalese: a population study. Br J Clin Pharmacol 1994;38:466-70.
-
(1994)
Br J Clin Pharmacol
, vol.38
, pp. 466-470
-
-
Weerasuriya, K.1
Jayakody, R.L.2
Smith, C.A.D.3
Wolf, C.R.4
Tucker, G.T.5
Lennard, M.S.6
-
22
-
-
0025342853
-
Correlations among the metabolic ratios of three test probes (metoprolol, debrisoquine and sparteine) for genetically determined oxidation polymorphism in a Japanese population
-
Horai Y, Taga J, Ishizaki T, Ishikawa K. Correlations among the metabolic ratios of three test probes (metoprolol, debrisoquine and sparteine) for genetically determined oxidation polymorphism in a Japanese population. Br J Clin Pharmacol 1990;29:111-5.
-
(1990)
Br J Clin Pharmacol
, vol.29
, pp. 111-115
-
-
Horai, Y.1
Taga, J.2
Ishizaki, T.3
Ishikawa, K.4
-
23
-
-
0028603653
-
Pharmacogenetics and drug metabolism of newer antidepressant agents
-
De Vane CL. Pharmacogenetics and drug metabolism of newer antidepressant agents. J Clin Psychiatry 1994;55 suppl:38-45.
-
(1994)
J Clin Psychiatry
, vol.55
, Issue.SUPPL.
, pp. 38-45
-
-
De Vane, C.L.1
-
24
-
-
0027534276
-
Molecular basis for rational megaprescribing in ultrarapid hydroxylators of debrisoquine
-
Bertilsson L, Dahl ML, Sjøqvist F, Aberg-Wistedt A, Humble M, Johansson I, et al. Molecular basis for rational megaprescribing in ultrarapid hydroxylators of debrisoquine. Lancet 1993;341:63.
-
(1993)
Lancet
, vol.341
, pp. 63
-
-
Bertilsson, L.1
Dahl, M.L.2
Sjøqvist, F.3
Aberg-Wistedt, A.4
Humble, M.5
Johansson, I.6
-
25
-
-
0026553661
-
A predictive model for substrates of cytochrome P-450 debrisoquine (2D6)
-
Koymans LMH, Vermeulen NPE, Van Acker SABE, Te Koppele JM, Heykants JJP, Lavrijsen K, et al. A predictive model for substrates of cytochrome P-450 debrisoquine (2D6). Chem Res Toxicol 1992;5:211-9.
-
(1992)
Chem Res Toxicol
, vol.5
, pp. 211-219
-
-
Koymans, L.M.H.1
Vermeulen, N.P.E.2
Van Acker, S.A.B.E.3
Te Koppele, J.M.4
Heykants, J.J.P.5
Lavrijsen, K.6
-
27
-
-
0025729217
-
Clinical consequences of polymorphic drug oxidation
-
Alvan G. Clinical consequences of polymorphic drug oxidation. Fundam Clin Pharmacol 1991;5:209-28.
-
(1991)
Fundam Clin Pharmacol
, vol.5
, pp. 209-228
-
-
Alvan, G.1
-
28
-
-
0028289040
-
Clinical implications of genetic polymorphism in drug metabolism
-
Tucker GT. Clinical implications of genetic polymorphism in drug metabolism. J Pharm Pharmacol 1994;46 suppl 1:417-24.
-
(1994)
J Pharm Pharmacol
, vol.46
, Issue.1 SUPPL.
, pp. 417-424
-
-
Tucker, G.T.1
-
29
-
-
0027167806
-
Polymorphic 2-hydroxylation of desipramine. A population and family study
-
Dahl ML, Iselius L, Alm C, Svensson JO, Lee D, Johansson I, et al. Polymorphic 2-hydroxylation of desipramine. A population and family study. Eur J Clin Pharmacol 1993;44:445-50.
-
(1993)
Eur J Clin Pharmacol
, vol.44
, pp. 445-450
-
-
Dahl, M.L.1
Iselius, L.2
Alm, C.3
Svensson, J.O.4
Lee, D.5
Johansson, I.6
-
30
-
-
0025218419
-
Clinical pharmacokinetics of imipramine and desipramine
-
Sallee FR, Pollock BG. Clinical pharmacokinetics of imipramine and desipramine. Clin Pharmacokinet 1990;18:346-64.
-
(1990)
Clin Pharmacokinet
, vol.18
, pp. 346-364
-
-
Sallee, F.R.1
Pollock, B.G.2
-
31
-
-
0023032092
-
Imipramine demethylation and hydroxylation: Impact of the sparteine oxidation phenotype
-
Brøsen K, Otton SV, Gram LF. Imipramine demethylation and hydroxylation: impact of the sparteine oxidation phenotype. Clin Pharmacol Ther 1986;40:543-9.
-
(1986)
Clin Pharmacol Ther
, vol.40
, pp. 543-549
-
-
Brøsen, K.1
Otton, S.V.2
Gram, L.F.3
-
32
-
-
0021933958
-
Plasma concentrations of nortriptyline and its 10-hydroxy metabolite in depressed patients. Relationship to the debrisoquine hydroxylation metabolic ratio
-
Nordin C, Siwers B, Benitez J, Bertilsson L. Plasma concentrations of nortriptyline and its 10-hydroxy metabolite in depressed patients. Relationship to the debrisoquine hydroxylation metabolic ratio. Br J Clin Pharmacol 1985;19:832-5.
-
(1985)
Br J Clin Pharmacol
, vol.19
, pp. 832-835
-
-
Nordin, C.1
Siwers, B.2
Benitez, J.3
Bertilsson, L.4
-
33
-
-
0019449455
-
E- and Z-10-hydroxylation of nortriptyline: Relationship to polymorphic debrisoquine hydroxlation
-
Mellstrøm B, Bertilsson L, Sawe J, Schulz HU, Sjøqvist F. E- and Z-10-hydroxylation of nortriptyline: Relationship to polymorphic debrisoquine hydroxlation. Clin Pharmacol Ther 1981;30:189-93.
-
(1981)
Clin Pharmacol Ther
, vol.30
, pp. 189-193
-
-
Mellstrøm, B.1
Bertilsson, L.2
Sawe, J.3
Schulz, H.U.4
Sjøqvist, F.5
-
34
-
-
0024465177
-
Steady-state plasma levels of E- and Z-10-OH-nortriptyline in nortriptyline-treated patients: Significance of concurrent medication and the sparteine oxidation phenotype
-
Gram LF, Brøsen K, Kragh-Sorensen P, Christensen P. Steady-state plasma levels of E- and Z-10-OH-nortriptyline in nortriptyline-treated patients: significance of concurrent medication and the sparteine oxidation phenotype. Ther Drug Monit 1989;11:508-14.
-
(1989)
Ther Drug Monit
, vol.11
, pp. 508-514
-
-
Gram, L.F.1
Brøsen, K.2
Kragh-Sorensen, P.3
Christensen, P.4
-
35
-
-
0024333471
-
Disposition of perphenazine is related to polymorphic debrisoquin hydroxylation in human beings
-
Dahl-Puustinen ML, Liden A, Alm C, Nordin C, Bertilsson L. Disposition of perphenazine is related to polymorphic debrisoquin hydroxylation in human beings. Clin Pharmacol Ther 1989;46:78-81.
-
(1989)
Clin Pharmacol Ther
, vol.46
, pp. 78-81
-
-
Dahl-Puustinen, M.L.1
Liden, A.2
Alm, C.3
Nordin, C.4
Bertilsson, L.5
-
36
-
-
0027135349
-
Influence of CYP2D6-dependent metabolism on the steady-state pharmacokinetics and pharmacodynamics of metoprolol and nicardipine, alone and in combination
-
Laurent-Kenesi MA, Funck-Brentano C, Poirier JM, Decolin D. Jaillon P. Influence of CYP2D6-dependent metabolism on the steady-state pharmacokinetics and pharmacodynamics of metoprolol and nicardipine, alone and in combination. Br J Clin Pharmacol 1993;36:531-8.
-
(1993)
Br J Clin Pharmacol
, vol.36
, pp. 531-538
-
-
Laurent-Kenesi, M.A.1
Funck-Brentano, C.2
Poirier, J.M.3
Decolin, D.4
Jaillon, P.5
-
37
-
-
0024514790
-
Timolol metabolism and debrisoquine oxidation polymorphism: A population study
-
Lennard MS, Lewis RV, Brawn LA, Tucker GT, Ramsay LE, Jackson PR, et al. Timolol metabolism and debrisoquine oxidation polymorphism: a population study. Br J Clin Pharmacol 1989;27:429-34.
-
(1989)
Br J Clin Pharmacol
, vol.27
, pp. 429-434
-
-
Lennard, M.S.1
Lewis, R.V.2
Brawn, L.A.3
Tucker, G.T.4
Ramsay, L.E.5
Jackson, P.R.6
-
38
-
-
0025824216
-
Disposition of the neuroleptic zuclopentixol cosegregates with the polymorphic hydroxylation of debrisoquine in humans
-
Dahl ML, Ekqvist B, Widen J, Bertilsson L. Disposition of the neuroleptic zuclopentixol cosegregates with the polymorphic hydroxylation of debrisoquine in humans. Acta Psychiatr Scand 1991;84:99-102.
-
(1991)
Acta Psychiatr Scand
, vol.84
, pp. 99-102
-
-
Dahl, M.L.1
Ekqvist, B.2
Widen, J.3
Bertilsson, L.4
-
39
-
-
0026576928
-
Pharmacokinetics of the selective serotonin reuptake inhibitor paroxetine: Nonlinearity and relation to the sparteine oxidation polymorphism
-
Sindrup SH, Brøsen K, Gram LF. Pharmacokinetics of the selective serotonin reuptake inhibitor paroxetine: nonlinearity and relation to the sparteine oxidation polymorphism. Clin Pharmacol Ther 1992;51:288-95.
-
(1992)
Clin Pharmacol Ther
, vol.51
, pp. 288-295
-
-
Sindrup, S.H.1
Brøsen, K.2
Gram, L.F.3
-
40
-
-
0026606822
-
The relationship between paroxetine and the sparteine oxidation polymorphism
-
Sindrup SH, Brøsen K, Gram LF, Hallas J, Skjelbø E, Allen A, et al. The relationship between paroxetine and the sparteine oxidation polymorphism. Clin Pharmacol Ther 1992;51:278-87.
-
(1992)
Clin Pharmacol Ther
, vol.51
, pp. 278-287
-
-
Sindrup, S.H.1
Brøsen, K.2
Gram, L.F.3
Hallas, J.4
Skjelbø, E.5
Allen, A.6
-
41
-
-
0027383271
-
The pharmacokinetics of the selective serotonin reuptake inhibitors
-
Brøsen K. The pharmacokinetics of the selective serotonin reuptake inhibitors. Clin Invest 1993;71:1002-9.
-
(1993)
Clin Invest
, vol.71
, pp. 1002-1009
-
-
Brøsen, K.1
-
42
-
-
0025829102
-
Extremely slow metabolism of amitriptyline but normal metabolism of imipramine and desipramine in an extensive metabolizer of sparteine, debrisoquine, and mephenytoin
-
Brøsen K, Gram LF, Kragh-Sorensen P. Extremely slow metabolism of amitriptyline but normal metabolism of imipramine and desipramine in an extensive metabolizer of sparteine, debrisoquine, and mephenytoin. Ther Drug Monit 1991;13:177-82.
-
(1991)
Ther Drug Monit
, vol.13
, pp. 177-182
-
-
Brøsen, K.1
Gram, L.F.2
Kragh-Sorensen, P.3
-
43
-
-
0027167470
-
Inhibition by paroxetine of desipramine metabolism in extensive but not in poor metabolizers of sparteine
-
Brøsen K, Hansen JG, Nielsen KK, Sindrup SH, Gram LF. Inhibition by paroxetine of desipramine metabolism in extensive but not in poor metabolizers of sparteine. Eur J Clin Pharmacol 1993;44:349-55.
-
(1993)
Eur J Clin Pharmacol
, vol.44
, pp. 349-355
-
-
Brøsen, K.1
Hansen, J.G.2
Nielsen, K.K.3
Sindrup, S.H.4
Gram, L.F.5
-
44
-
-
0026692983
-
Haloperidol disposition is dependent on debrisoquine hydroxylation phenotype
-
Llerena A, Alm C, Dahl M-L, Ekqvist B, Bertilsson L. Haloperidol disposition is dependent on debrisoquine hydroxylation phenotype. Ther Drug Monit 1992;14:92-7.
-
(1992)
Ther Drug Monit
, vol.14
, pp. 92-97
-
-
Llerena, A.1
Alm, C.2
Dahl, M.-L.3
Ekqvist, B.4
Bertilsson, L.5
-
45
-
-
0024580258
-
Substantial rise in sparteine metabolic ratio during haloperidol treatment
-
Gram LF, Debruyne D, Caillard V, Boulenger JP, Lacotte J, Moulin M, et al. Substantial rise in sparteine metabolic ratio during haloperidol treatment. Br J Clin Pharmacol 1989;27:272-5.
-
(1989)
Br J Clin Pharmacol
, vol.27
, pp. 272-275
-
-
Gram, L.F.1
Debruyne, D.2
Caillard, V.3
Boulenger, J.P.4
Lacotte, J.5
Moulin, M.6
-
46
-
-
0026051838
-
The metabolism of mexiletine in relation to the debrisoquine/sparteine-type polymorphism of drug oxidation
-
Broly F, Vandamme N, Libersa C, Lhermitte M. The metabolism of mexiletine in relation to the debrisoquine/sparteine-type polymorphism of drug oxidation. Br J Clin Pharmacol 1991;32:459-66.
-
(1991)
Br J Clin Pharmacol
, vol.32
, pp. 459-466
-
-
Broly, F.1
Vandamme, N.2
Libersa, C.3
Lhermitte, M.4
-
47
-
-
0027486736
-
Role of cytochrome P450IID6 in the metabolism of brofaromine. A new selective MAO-A inhibitor
-
Feifel N, Kucher K, Fuchs L, Jedrychowsky M, Schmiedt E, Antonin KH, et al. Role of cytochrome P450IID6 in the metabolism of brofaromine. A new selective MAO-A inhibitor. Eur J Clin Pharmacol 1993;45:265-9.
-
(1993)
Eur J Clin Pharmacol
, vol.45
, pp. 265-269
-
-
Feifel, N.1
Kucher, K.2
Fuchs, L.3
Jedrychowsky, M.4
Schmiedt, E.5
Antonin, K.H.6
-
48
-
-
0026019030
-
Polymorphic flecainide disposition under conditions of uncontrolled urine flow and pH
-
Gross AS, Mikus G, Fischer C, Eichelbaum M. Polymorphic flecainide disposition under conditions of uncontrolled urine flow and pH. Eur J Clin Pharmacol 1991;40:155-62.
-
(1991)
Eur J Clin Pharmacol
, vol.40
, pp. 155-162
-
-
Gross, A.S.1
Mikus, G.2
Fischer, C.3
Eichelbaum, M.4
-
49
-
-
0027183378
-
Pharmacology, toxicology and human pharmacokinetics of tropisetron
-
Kutz K. Pharmacology, toxicology and human pharmacokinetics of tropisetron. Ann Oncol 1993;4 suppl:S15-8.
-
(1993)
Ann Oncol
, vol.4
, Issue.SUPPL.
-
-
Kutz, K.1
-
50
-
-
0028223289
-
The polymorphic cytochrome P-4502D6 is involved in the metabolism of both 5-hydroxytryptamine antagonists, tropisetron and ondansetron
-
Fischer V, Vickers AE, Heitz F, Mahadevan S, Baldeck JP, Minery P, et al. The polymorphic cytochrome P-4502D6 is involved in the metabolism of both 5-hydroxytryptamine antagonists, tropisetron and ondansetron. Drug Metab Dispos 1994;22:269-74.
-
(1994)
Drug Metab Dispos
, vol.22
, pp. 269-274
-
-
Fischer, V.1
Vickers, A.E.2
Heitz, F.3
Mahadevan, S.4
Baldeck, J.P.5
Minery, P.6
-
51
-
-
0026795695
-
Inhibitors of imipramine metabolism by human liver microsomes
-
Skjelbø E, Brøsen K. Inhibitors of imipramine metabolism by human liver microsomes. Br J Clin Pharmacol 1992;34:256-61.
-
(1992)
Br J Clin Pharmacol
, vol.34
, pp. 256-261
-
-
Skjelbø, E.1
Brøsen, K.2
-
52
-
-
0027389155
-
The N-demethylation of imipramine correlates with the oxidation of S-mephenytoin (S/R-ratio): A population study
-
Skjelbø E, Gram LF, Brøsen K. The N-demethylation of imipramine correlates with the oxidation of S-mephenytoin (S/R-ratio): a population study. Br J Clin Pharmacol 1993;35:331-4.
-
(1993)
Br J Clin Pharmacol
, vol.35
, pp. 331-334
-
-
Skjelbø, E.1
Gram, L.F.2
Brøsen, K.3
-
53
-
-
0022510805
-
Steady-state concentrations of imipramine and its metabolites in relation to the sparteine/debrisoquine polymorphism
-
Brøsen K, Klysner R, Gram LF, Otton SV, Bech P, Bertilsson L. Steady-state concentrations of imipramine and its metabolites in relation to the sparteine/debrisoquine polymorphism. Eur J Clin Pharmacol 1986;30:679-84.
-
(1986)
Eur J Clin Pharmacol
, vol.30
, pp. 679-684
-
-
Brøsen, K.1
Klysner, R.2
Gram, L.F.3
Otton, S.V.4
Bech, P.5
Bertilsson, L.6
-
54
-
-
0023774419
-
The relationship between imipramine metabolism and the sparteine oxidation polymorphism
-
Brøsen K. The relationship between imipramine metabolism and the sparteine oxidation polymorphism. Dan Med Bull 1988;35:460-8.
-
(1988)
Dan Med Bull
, vol.35
, pp. 460-468
-
-
Brøsen, K.1
-
55
-
-
0025733250
-
Role of P450IID6, the target of the sparteine-debrisoquine oxidation polymorphism, in the metabolism of imipramine
-
Brøsen K, Zeugin T, Meyer UA. Role of P450IID6, the target of the sparteine-debrisoquine oxidation polymorphism, in the metabolism of imipramine. Clin Pharmacol Ther 1991;49:609-17.
-
(1991)
Clin Pharmacol Ther
, vol.49
, pp. 609-617
-
-
Brøsen, K.1
Zeugin, T.2
Meyer, U.A.3
-
56
-
-
0023905440
-
First-pass metabolism of imipramine and desipramine: Impact of the sparteine oxidation phenotype
-
Brøsen K, Gram LF. First-pass metabolism of imipramine and desipramine: Impact of the sparteine oxidation phenotype. Clin Pharmacol Ther 1988;43:400-6.
-
(1988)
Clin Pharmacol Ther
, vol.43
, pp. 400-406
-
-
Brøsen, K.1
Gram, L.F.2
-
57
-
-
0028303496
-
Single-dose kinetics of clomipramine: Relationship to the sparteine and S-mephenytoin oxidation polymorphisms
-
Nielsen KK, Brøsen K, Hansen MG, Gram LF. Single-dose kinetics of clomipramine: relationship to the sparteine and S-mephenytoin oxidation polymorphisms. Clin Pharmacol Ther 1994;55:518-27.
-
(1994)
Clin Pharmacol Ther
, vol.55
, pp. 518-527
-
-
Nielsen, K.K.1
Brøsen, K.2
Hansen, M.G.3
Gram, L.F.4
-
58
-
-
0022898438
-
Importance of oxidative polymorphism and levomepromazine treatment on the steady-state blood concentrations of clomipramine and its major metabolites
-
Balant-Gorgia AE, Balant LP, Genet C, Dayer P, Aeschlimann JM, Garrone G. Importance of oxidative polymorphism and levomepromazine treatment on the steady-state blood concentrations of clomipramine and its major metabolites. Eur J Clin Pharmacol 1986;31:449-55.
-
(1986)
Eur J Clin Pharmacol
, vol.31
, pp. 449-455
-
-
Balant-Gorgia, A.E.1
Balant, L.P.2
Genet, C.3
Dayer, P.4
Aeschlimann, J.M.5
Garrone, G.6
-
59
-
-
0023107513
-
High plasma concentrations of desmethylclomipramine after chronic administration of clomipramine to a poor metabolizer
-
Balant-Gorgia AE, Balant L, Zysset Th. High plasma concentrations of desmethylclomipramine after chronic administration of clomipramine to a poor metabolizer. Eur J Clin Pharmacol 1987;32:101-2.
-
(1987)
Eur J Clin Pharmacol
, vol.32
, pp. 101-102
-
-
Balant-Gorgia, A.E.1
Balant, L.2
Zysset, Th.3
-
60
-
-
0026739661
-
Steady-state plasma levels of clomipramine and its metabolites: Impact of the sparteine/debrisoquine polymorphism
-
Nielsen KK, Brøsen K, Gram LF. Steady-state plasma levels of clomipramine and its metabolites: impact of the sparteine/debrisoquine polymorphism. Eur J Clin Pharmacol 1992;43:405-11.
-
(1992)
Eur J Clin Pharmacol
, vol.43
, pp. 405-411
-
-
Nielsen, K.K.1
Brøsen, K.2
Gram, L.F.3
-
61
-
-
0024600366
-
Effect of low dose quinidine on encainide pharmacokinetics and pharmacodynamics. Influence of genetic polymorphism
-
Funck-Brntano C, Turgeon J, Woosley R, Roden DM. Effect of low dose quinidine on encainide pharmacokinetics and pharmacodynamics. Influence of genetic polymorphism. J Pharmacol Exp Ther 1989;249:134-42.
-
(1989)
J Pharmacol Exp Ther
, vol.249
, pp. 134-142
-
-
Funck-Brntano, C.1
Turgeon, J.2
Woosley, R.3
Roden, D.M.4
-
62
-
-
0022539834
-
Oxidative metabolism of encainide: Polymorphism, pharmacokinetics and clinical considerations
-
McAllister CB, Wolfenden HT, Aslanian WS, Woosley RL, Wilkinson GR. Oxidative metabolism of encainide: polymorphism, pharmacokinetics and clinical considerations. Xenobiotica 1986;16:483-90.
-
(1986)
Xenobiotica
, vol.16
, pp. 483-490
-
-
McAllister, C.B.1
Wolfenden, H.T.2
Aslanian, W.S.3
Woosley, R.L.4
Wilkinson, G.R.5
-
64
-
-
0023122069
-
Polymorphism of propafenone metabolism and disposition in man: Clinical and pharmacokinetic consequences
-
Siddoway LA, Thompson KA, McAllister CB, Wang T, Wilkinson GR, Roden DM, et al. Polymorphism of propafenone metabolism and disposition in man: clinical and pharmacokinetic consequences. Circulation 1987;75:785-91.
-
(1987)
Circulation
, vol.75
, pp. 785-791
-
-
Siddoway, L.A.1
Thompson, K.A.2
McAllister, C.B.3
Wang, T.4
Wilkinson, G.R.5
Roden, D.M.6
-
65
-
-
0027460033
-
Identification and characterization of the cytochrome P450 enzymes involved in N-dealkylation of propafenone: Molecular base for interaction potential and variable disposition of active metabolites
-
Botsch S, Gautier JC, Beaune P, Eichelbaum M, Kroemer HK. Identification and characterization of the cytochrome P450 enzymes involved in N-dealkylation of propafenone: molecular base for interaction potential and variable disposition of active metabolites. Mol Pharmacol 1993;43:120-6.
-
(1993)
Mol Pharmacol
, vol.43
, pp. 120-126
-
-
Botsch, S.1
Gautier, J.C.2
Beaune, P.3
Eichelbaum, M.4
Kroemer, H.K.5
-
66
-
-
0024534047
-
Propranolol's metabolism is determined by both mephenytoin and debrisoquin hydroxylase activities
-
Ward SA, Walle T, Walle UK, Wilkinson GR, Branch RA. Propranolol's metabolism is determined by both mephenytoin and debrisoquin hydroxylase activities. Clin Pharmacol Ther 1989;45:72-9.
-
(1989)
Clin Pharmacol Ther
, vol.45
, pp. 72-79
-
-
Ward, S.A.1
Walle, T.2
Walle, U.K.3
Wilkinson, G.R.4
Branch, R.A.5
-
67
-
-
0022336984
-
β-Blockers and genetic polymorphism. Polymorphic metabolism of the β-adrenoreceptor blocking drugs and its clinical relevance
-
Smith RL. β-Blockers and genetic polymorphism. Polymorphic metabolism of the β-adrenoreceptor blocking drugs and its clinical relevance. Eur J Clin Pharmacol 1985;28 suppl:77-84.
-
(1985)
Eur J Clin Pharmacol
, vol.28
, Issue.SUPPL.
, pp. 77-84
-
-
Smith, R.L.1
-
68
-
-
0027433081
-
Absorption, metabolism, and excretion of risperidone in humans
-
Mannens G, Huang ML, Meuldermans W, Hendrickx J, Woestenborghs R, Heykants J. Absorption, metabolism, and excretion of risperidone in humans. Drug Metab Dispos 1993;21:1134-41.
-
(1993)
Drug Metab Dispos
, vol.21
, pp. 1134-1141
-
-
Mannens, G.1
Huang, M.L.2
Meuldermans, W.3
Hendrickx, J.4
Woestenborghs, R.5
Heykants, J.6
-
69
-
-
0028361351
-
The pharmacokinetics of risperidone in humans: A summary
-
Heykants J, Huang ML, Mannens G, Meuldermans W, Snoeck E, Van Bijsterveldt L, et al. The pharmacokinetics of risperidone in humans: a summary. J Clin Psychiatry 1994;55 suppl:13-7.
-
(1994)
J Clin Psychiatry
, vol.55
, Issue.SUPPL.
, pp. 13-17
-
-
Heykants, J.1
Huang, M.L.2
Mannens, G.3
Meuldermans, W.4
Snoeck, E.5
Van Bijsterveldt, L.6
-
70
-
-
0028203650
-
The pharmacology of tramadol
-
Dayer P, Collart L, Desmeules J. The pharmacology of tramadol. Drugs 1994;47 suppl 1:3-7.
-
(1994)
Drugs
, vol.47
, Issue.1 SUPPL.
, pp. 3-7
-
-
Dayer, P.1
Collart, L.2
Desmeules, J.3
-
71
-
-
0028282613
-
Maprotiline metabolism appears to cosegregate with the genetically determined CYP2D6 polymorphic hydroxylation of debrisoquine
-
Firkusny L, Gleiter CH. Maprotiline metabolism appears to cosegregate with the genetically determined CYP2D6 polymorphic hydroxylation of debrisoquine. Br J Clin Pharmacol 1994;37:383-8.
-
(1994)
Br J Clin Pharmacol
, vol.37
, pp. 383-388
-
-
Firkusny, L.1
Gleiter, C.H.2
-
72
-
-
0027980392
-
Stereoselective disposition of mianserin is related to debrisoquine hydroxylation polymorphism
-
Dahl ML, Tybring G, Elwin CE, Alm C, Andreasson K, Gyllenpalm M, et al. Stereoselective disposition of mianserin is related to debrisoquine hydroxylation polymorphism. Clin Pharmacol Ther 1994;56:176-83.
-
(1994)
Clin Pharmacol Ther
, vol.56
, pp. 176-183
-
-
Dahl, M.L.1
Tybring, G.2
Elwin, C.E.3
Alm, C.4
Andreasson, K.5
Gyllenpalm, M.6
-
73
-
-
0025853291
-
Disposition and metabolism of codeine after single and chronic doses in one poor and seven extensive metabolisers
-
Chen ZR, Somogyi AA, Reynolds G, Bochner F. Disposition and metabolism of codeine after single and chronic doses in one poor and seven extensive metabolisers. Br J Clin Pharmacol 1991;31:381-90.
-
(1991)
Br J Clin Pharmacol
, vol.31
, pp. 381-390
-
-
Chen, Z.R.1
Somogyi, A.A.2
Reynolds, G.3
Bochner, F.4
-
74
-
-
0026030901
-
Codeine O-demethylation: Rat strain differences and the effects of inhibitors
-
Mikus G, Somogyi AA, Bochner F, Eichelbaum M. Codeine O-demethylation: rat strain differences and the effects of inhibitors. Biochem Pharmacol 1991;41:757-62.
-
(1991)
Biochem Pharmacol
, vol.41
, pp. 757-762
-
-
Mikus, G.1
Somogyi, A.A.2
Bochner, F.3
Eichelbaum, M.4
-
75
-
-
0023795013
-
Polymorphic O-demethylation of codeine
-
Chen ZR, Somogyi AA, Bochner F. Polymorphic O-demethylation of codeine. Lancet 1988;2:914-5.
-
(1988)
Lancet
, vol.2
, pp. 914-915
-
-
Chen, Z.R.1
Somogyi, A.A.2
Bochner, F.3
-
76
-
-
0020592679
-
Amitriptyline metabolism: Relationship to polymorphic debrisoquine hydroxylation
-
Mellstrom B, Bertilsson L, Lou YC, Sawe J, Sjøqvist F. Amitriptyline metabolism: relationship to polymorphic debrisoquine hydroxylation. Clin Pharmacol Ther 1983;34:516-20.
-
(1983)
Clin Pharmacol Ther
, vol.34
, pp. 516-520
-
-
Mellstrom, B.1
Bertilsson, L.2
Lou, Y.C.3
Sawe, J.4
Sjøqvist, F.5
-
77
-
-
0027472058
-
Pharmacokinetics of citalopram in relation to the sparteine and the mephenytoin oxidation polymorphisms
-
Sindrup SH, Brøsen K, Hansen MG, Aaes-Jorgensen T, Overo KF, Gram LF. Pharmacokinetics of citalopram in relation to the sparteine and the mephenytoin oxidation polymorphisms. Ther Drug Monit 1993;15:11-7.
-
(1993)
Ther Drug Monit
, vol.15
, pp. 11-17
-
-
Sindrup, S.H.1
Brøsen, K.2
Hansen, M.G.3
Aaes-Jorgensen, T.4
Overo, K.F.5
Gram, L.F.6
-
78
-
-
0025951067
-
Clinical implications of the competitive inhibition of the debrisoquine-metabolizing isozyme by quinidine
-
Caporaso NE, Shaw GL. Clinical implications of the competitive inhibition of the debrisoquine-metabolizing isozyme by quinidine. Arch Intern Med 1991;151:1985-92.
-
(1991)
Arch Intern Med
, vol.151
, pp. 1985-1992
-
-
Caporaso, N.E.1
Shaw, G.L.2
-
79
-
-
0021125904
-
Stereoselective metabolism and pharmacogenetic control of 5-phenyl-5-ethylhydantoin (Nirvanol) in humans
-
Kupfer A, Patwardhan R, Ward S, Schenker S, Preisig R, Branch RA. Stereoselective metabolism and pharmacogenetic control of 5-phenyl-5-ethylhydantoin (Nirvanol) in humans. J Pharmacol Exp Ther 1984;230:28-33.
-
(1984)
J Pharmacol Exp Ther
, vol.230
, pp. 28-33
-
-
Kupfer, A.1
Patwardhan, R.2
Ward, S.3
Schenker, S.4
Preisig, R.5
Branch, R.A.6
-
80
-
-
0028260641
-
The major genetic defect responsible for the polymorphism of S-mephenytoin metabolism in humans
-
De Morais SM, Wilkinson GR, Blaisdell J, Nakamura K, Meyer UA, Goldstein JA. The major genetic defect responsible for the polymorphism of S-mephenytoin metabolism in humans. J Biol Chem 1994;269:15419-22.
-
(1994)
J Biol Chem
, vol.269
, pp. 15419-15422
-
-
De Morais, S.M.1
Wilkinson, G.R.2
Blaisdell, J.3
Nakamura, K.4
Meyer, U.A.5
Goldstein, J.A.6
-
81
-
-
0028892079
-
S-Mephenytoin hydroxylation phenotypes in a Jordan population
-
Hadidi HF, Irshaid YM, Woosley RL, Idle JR, Flockhart DA. S-Mephenytoin hydroxylation phenotypes in a Jordan population. Clin Pharmacol Ther 1995;58:542-7.
-
(1995)
Clin Pharmacol Ther
, vol.58
, pp. 542-547
-
-
Hadidi, H.F.1
Irshaid, Y.M.2
Woosley, R.L.3
Idle, J.R.4
Flockhart, D.A.5
-
82
-
-
0027253112
-
Frequency of S-mephenytoin hydroxylation deficiency in 373 Spanish subjects compared to other Caucasian populations
-
Reviriego J, Bertilsson L, Carillo JA, Llerena A, Valdivielso MJ, Benitez J. Frequency of S-mephenytoin hydroxylation deficiency in 373 Spanish subjects compared to other Caucasian populations. Eur J Clin Pharmacol 1993;44:593-5.
-
(1993)
Eur J Clin Pharmacol
, vol.44
, pp. 593-595
-
-
Reviriego, J.1
Bertilsson, L.2
Carillo, J.A.3
Llerena, A.4
Valdivielso, M.J.5
Benitez, J.6
-
83
-
-
0026705708
-
Incidence of S-mephenytoin hydroxylation deficiency in a Korean population and the interphenotypic differences in diazepam pharmacokinetics
-
Sohn DR, Kusaka M, Ishizaki T, Shin SG, Jang IJ, Shin JG, et al. Incidence of S-mephenytoin hydroxylation deficiency in a Korean population and the interphenotypic differences in diazepam pharmacokinetics. Clin Pharmacol Ther 1992;52:160-9.
-
(1992)
Clin Pharmacol Ther
, vol.52
, pp. 160-169
-
-
Sohn, D.R.1
Kusaka, M.2
Ishizaki, T.3
Shin, S.G.4
Jang, I.J.5
Shin, J.G.6
-
84
-
-
0028030327
-
Dapsone N-acetylation, metoprolol alpha-hydroxylation, and S-mephenytoin 4-hydroxylation polymorphisms in an Indonesian population: A cocktail and extended phenotyping assessment trial
-
Setiabudy R, Kusaka M, Chiba K, Darmansjah I, Ishizaki T. Dapsone N-acetylation, metoprolol alpha-hydroxylation, and S-mephenytoin 4-hydroxylation polymorphisms in an Indonesian population: a cocktail and extended phenotyping assessment trial. Clin Pharmacol Ther 1994;56:142-53.
-
(1994)
Clin Pharmacol Ther
, vol.56
, pp. 142-153
-
-
Setiabudy, R.1
Kusaka, M.2
Chiba, K.3
Darmansjah, I.4
Ishizaki, T.5
-
85
-
-
0024580554
-
Importance of genetic factors in the regulation of diazepam metabolism: Relation to S-mephenytoin, but not debrisoquin hydroxylation phenotype
-
Bertilsson L, Henthorn TK, Sanz E, Tybring G, Sawe J, Villen T. Importance of genetic factors in the regulation of diazepam metabolism: relation to S-mephenytoin, but not debrisoquin hydroxylation phenotype. Clin Pharmacol Ther 1989;45:348-55.
-
(1989)
Clin Pharmacol Ther
, vol.45
, pp. 348-355
-
-
Bertilsson, L.1
Henthorn, T.K.2
Sanz, E.3
Tybring, G.4
Sawe, J.5
Villen, T.6
-
86
-
-
0027744044
-
Cytochrome P450 mediated metabolism of diazepam in human and rat: Involvement of human CYP2C in N-demethylation in the substrate concentration-dependent manner
-
Yasumori T, Nagata K, Yang SK, Chen LS, Murayama N, Yamazoe Y, et al. Cytochrome P450 mediated metabolism of diazepam in human and rat: involvement of human CYP2C in N-demethylation in the substrate concentration-dependent manner. Pharmacogenetics 1993;3:291-301.
-
(1993)
Pharmacogenetics
, vol.3
, pp. 291-301
-
-
Yasumori, T.1
Nagata, K.2
Yang, S.K.3
Chen, L.S.4
Murayama, N.5
Yamazoe, Y.6
-
87
-
-
0025296575
-
Cytochrome P450IIIA enzymes in rat liver microsomes: Involvement in C3-hydroxylation of diazepam and nordazepam but not in N-dealkylation of diazepam and temazepam
-
Reilly PE, Thompson DA, Mason SR, Hooper WD. Cytochrome P450IIIA enzymes in rat liver microsomes: involvement in C3-hydroxylation of diazepam and nordazepam but not in N-dealkylation of diazepam and temazepam. Mol Pharmacol 1990;37:767-74.
-
(1990)
Mol Pharmacol
, vol.37
, pp. 767-774
-
-
Reilly, P.E.1
Thompson, D.A.2
Mason, S.R.3
Hooper, W.D.4
-
88
-
-
0025223056
-
Diazepam metabolism in native Chinese poor and extensive hydroxylators of S-mephenytoin: Interethnic differences in comparison with white subjects
-
Zhang Y, Reviriego J, Lou YQ, Sjøqvist F, Bertilsson L. Diazepam metabolism in native Chinese poor and extensive hydroxylators of S-mephenytoin: interethnic differences in comparison with white subjects. Clin Pharmacol Ther 1990;48:496-502.
-
(1990)
Clin Pharmacol Ther
, vol.48
, pp. 496-502
-
-
Zhang, Y.1
Reviriego, J.2
Lou, Y.Q.3
Sjøqvist, F.4
Bertilsson, L.5
-
89
-
-
0027208084
-
Why are diazepam metabolism and polymorphic S-mephenytoin hydroxylation associated with each other in white and in Korean populations but not in Chinese populations?
-
Bertilsson L, Kalow W. Why are diazepam metabolism and polymorphic S-mephenytoin hydroxylation associated with each other in white and in Korean populations but not in Chinese populations? Clin Pharmacol Ther 1993;53:608-9.
-
(1993)
Clin Pharmacol Ther
, vol.53
, pp. 608-609
-
-
Bertilsson, L.1
Kalow, W.2
-
90
-
-
0024448282
-
Diazepam treatment does not influence the debrisoquine or mephenytoin hydroxylation phenotypeing tests
-
Spina E, Buemi AL, Sanz E, Bertilsson L. Diazepam treatment does not influence the debrisoquine or mephenytoin hydroxylation phenotypeing tests. Ther Drug Monit 1989;11:721-3.
-
(1989)
Ther Drug Monit
, vol.11
, pp. 721-723
-
-
Spina, E.1
Buemi, A.L.2
Sanz, E.3
Bertilsson, L.4
-
91
-
-
0018395301
-
Pharmacogenetics of tolbutamide metabolism in humans
-
Scott J, Poffenbarger PL. Pharmacogenetics of tolbutamide metabolism in humans. Diabetes 1979;28:41-51.
-
(1979)
Diabetes
, vol.28
, pp. 41-51
-
-
Scott, J.1
Poffenbarger, P.L.2
-
92
-
-
0023355128
-
Hepatic metabolism of tolbutamide: Characterisation of the form of cytochrome P-450 involved in methylhydroxylation and relationship to in vivo disposition
-
Knodell RG, Hall SD, Wilkinson GR, Guengerich FP. Hepatic metabolism of tolbutamide: characterisation of the form of cytochrome P-450 involved in methylhydroxylation and relationship to in vivo disposition. J Pharmacol Exp Ther 1987;241:1112-9.
-
(1987)
J Pharmacol Exp Ther
, vol.241
, pp. 1112-1119
-
-
Knodell, R.G.1
Hall, S.D.2
Wilkinson, G.R.3
Guengerich, F.P.4
-
94
-
-
0025735576
-
The activation of the biguanide antimalarial proguanil cosegregates with the mephenytoin oxidation polymorphism. A panel study
-
Ward SA, Helsby NA, Skjelbø E, Brøsen K, Gram L, Breckenridge AM. The activation of the biguanide antimalarial proguanil cosegregates with the mephenytoin oxidation polymorphism. A panel study. Br J Clin Pharmacol 1991;31:689-92.
-
(1991)
Br J Clin Pharmacol
, vol.31
, pp. 689-692
-
-
Ward, S.A.1
Helsby, N.A.2
Skjelbø, E.3
Brøsen, K.4
Gram, L.5
Breckenridge, A.M.6
-
95
-
-
0027272518
-
Proguanil metabolism is determined by the mephenytoin oxidation polymorphism in Vietnamese living in Denmark
-
Brøsen K, Skjelbø E, Flachs H. Proguanil metabolism is determined by the mephenytoin oxidation polymorphism in Vietnamese living in Denmark. Br J Clin Pharmacol 1993;36:105-8.
-
(1993)
Br J Clin Pharmacol
, vol.36
, pp. 105-108
-
-
Brøsen, K.1
Skjelbø, E.2
Flachs, H.3
-
96
-
-
0028228630
-
In vitro proguanil activation to cycloguanil by human liver microsomes is mediated by CYP3A isoforms as well as by S-mephenytoin hydroxylase
-
Birkett DJ, Rees D, Andersson T, Gonzalez FJ, Miners JO, Veronese ME. In vitro proguanil activation to cycloguanil by human liver microsomes is mediated by CYP3A isoforms as well as by S-mephenytoin hydroxylase. Br J Clin Pharmacol 1994;37:413-20.
-
(1994)
Br J Clin Pharmacol
, vol.37
, pp. 413-420
-
-
Birkett, D.J.1
Rees, D.2
Andersson, T.3
Gonzalez, F.J.4
Miners, J.O.5
Veronese, M.E.6
-
97
-
-
0028352381
-
Disposition of drugs in cystic fibrosis. VI. In vivo activity of cytochrome P450 isoforms involved in the metabolism of (R)-warfarin (including P450 3A4) is not enhanced in cystic fibrosis
-
Wang JP, Unandhat JD, McNamara S, O'Sullivan TA, Smith AL, Trager WF, et al. Disposition of drugs in cystic fibrosis. VI. in vivo activity of cytochrome P450 isoforms involved in the metabolism of (R)-warfarin (including P450 3A4) is not enhanced in cystic fibrosis. Clin Pharmacol Ther 1994;55:528-34.
-
(1994)
Clin Pharmacol Ther
, vol.55
, pp. 528-534
-
-
Wang, J.P.1
Unandhat, J.D.2
McNamara, S.3
O'Sullivan, T.A.4
Smith, A.L.5
Trager, W.F.6
-
98
-
-
0029016328
-
Moclobemide, a substrate of CYP2C19 and a inhibitor of CYP2C19, CYP2D6, and CYP1A2: A panel study
-
Gram LF, Guentert TW, Grange S, Vistisen K, Brøsen K. Moclobemide, a substrate of CYP2C19 and a inhibitor of CYP2C19, CYP2D6, and CYP1A2: a panel study. Clin Pharmacol Ther 1995;57:670-7.
-
(1995)
Clin Pharmacol Ther
, vol.57
, pp. 670-677
-
-
Gram, L.F.1
Guentert, T.W.2
Grange, S.3
Vistisen, K.4
Brøsen, K.5
-
99
-
-
0029018767
-
The hydroxylation of omeprazole correlates with S-mephenytoin metabolism: A population study
-
Balian JD, Sukhova N, Harris JW, Hewett J, Pickle L, Goldstein JA, et al. The hydroxylation of omeprazole correlates with S-mephenytoin metabolism: a population study. Clin Pharmacol Ther 1995;57:662-9.
-
(1995)
Clin Pharmacol Ther
, vol.57
, pp. 662-669
-
-
Balian, J.D.1
Sukhova, N.2
Harris, J.W.3
Hewett, J.4
Pickle, L.5
Goldstein, J.A.6
-
100
-
-
0028211993
-
Interethnic differences in omeprazole metabolism in the two S-mephenytoin hydroxylation phenotypes studied in Caucasians and orientals
-
Ishizaki T, Sohn DR, Kobayashi K, Chiba K, Lee KH, Shin SG, et al. Interethnic differences in omeprazole metabolism in the two S-mephenytoin hydroxylation phenotypes studied in Caucasians and orientals. Ther Drug Monit 1994;16:214-5.
-
(1994)
Ther Drug Monit
, vol.16
, pp. 214-215
-
-
Ishizaki, T.1
Sohn, D.R.2
Kobayashi, K.3
Chiba, K.4
Lee, K.H.5
Shin, S.G.6
-
101
-
-
0025368026
-
Omeprazole is an arylhydrocarbon-like inducer of human hepatic cytochrome P450
-
Diaz D, Fabre I, Daujat M, Saint Aubert B, Bories P, Michel H, et al. Omeprazole is an arylhydrocarbon-like inducer of human hepatic cytochrome P450. Gastroenterology 1990;99:737-47.
-
(1990)
Gastroenterology
, vol.99
, pp. 737-747
-
-
Diaz, D.1
Fabre, I.2
Daujat, M.3
Saint Aubert, B.4
Bories, P.5
Michel, H.6
-
102
-
-
0028324680
-
Omeprazole and lansoprazole are mixed inducers of CYP1A and CYP3A in human hepatocytes in primary culture
-
Curi-Pedrosa R, Daujat M, Pichard L, Ourlin JC, Clair P, Gervot L. Omeprazole and lansoprazole are mixed inducers of CYP1A and CYP3A in human hepatocytes in primary culture. J Pharmacol Exp Ther 1994;269:384-92.
-
(1994)
J Pharmacol Exp Ther
, vol.269
, pp. 384-392
-
-
Curi-Pedrosa, R.1
Daujat, M.2
Pichard, L.3
Ourlin, J.C.4
Clair, P.5
Gervot, L.6
-
103
-
-
0029859728
-
Differences between white subjects and Chinese subjects in the in vivo inhibition of cytochrome P450s 2C19, 2D6, and 3A4 by omeprazole
-
Caraco Y, Wilkinson GR, Wood AJJ. Differences between white subjects and Chinese subjects in the in vivo inhibition of cytochrome P450s 2C19, 2D6, and 3A4 by omeprazole. Clin Pharmacol Ther 1996;60:396-404.
-
(1996)
Clin Pharmacol Ther
, vol.60
, pp. 396-404
-
-
Caraco, Y.1
Wilkinson, G.R.2
Wood, A.J.J.3
-
104
-
-
0029127629
-
Interethnic difference in omeprazole's inhibition of diazepam metabolism
-
Caraco Y, Tateishi T, Wood AJJ. Interethnic difference in omeprazole's inhibition of diazepam metabolism. Clin Pharmacol Ther 1995;58:62-72.
-
(1995)
Clin Pharmacol Ther
, vol.58
, pp. 62-72
-
-
Caraco, Y.1
Tateishi, T.2
Wood, A.J.J.3
-
105
-
-
0028036727
-
Selective biotransformation of taxol to 6 alpha-hydroxytaxol by human cytochrome P450IIC8
-
Rahman A, Korzekwa KR, Grogan J, Gonzalez FJ, Harris JW. Selective biotransformation of taxol to 6 alpha-hydroxytaxol by human cytochrome P450IIC8. Cancer Res 1994;54:5543-6.
-
(1994)
Cancer Res
, vol.54
, pp. 5543-5546
-
-
Rahman, A.1
Korzekwa, K.R.2
Grogan, J.3
Gonzalez, F.J.4
Harris, J.W.5
-
106
-
-
0027957132
-
Metabolism of taxol by human hepatic microsomes and liver slices: Participation of cytochrome P450 3A4 and an unknown P450 enzyme
-
Harris JW, Rahman A, Kim BR, Guengerich FP, Collins JM. Metabolism of taxol by human hepatic microsomes and liver slices: participation of cytochrome P450 3A4 and an unknown P450 enzyme. Cancer Res 1994;54:4026-35.
-
(1994)
Cancer Res
, vol.54
, pp. 4026-4035
-
-
Harris, J.W.1
Rahman, A.2
Kim, B.R.3
Guengerich, F.P.4
Collins, J.M.5
-
108
-
-
0026696993
-
In vitro oxidation of oxicam NSAID by a human liver cytochrome P450
-
Zhao J, Leeman T, Dayer P. In vitro oxidation of oxicam NSAID by a human liver cytochrome P450. Life Sci 1992;51:575-81.
-
(1992)
Life Sci
, vol.51
, pp. 575-581
-
-
Zhao, J.1
Leeman, T.2
Dayer, P.3
-
109
-
-
0027770062
-
Absence of correlations among three putative in vivo probes of human cytochrome P4503A activity in young healthy men
-
Kinirons MT, O'Shea D, Downing TE, Fitzwilliam AT, Joellenbeck L, Groopman JD, et al. Absence of correlations among three putative in vivo probes of human cytochrome P4503A activity in young healthy men. Clin Pharmacol Ther 1993;54:621-9.
-
(1993)
Clin Pharmacol Ther
, vol.54
, pp. 621-629
-
-
Kinirons, M.T.1
O'Shea, D.2
Downing, T.E.3
Fitzwilliam, A.T.4
Joellenbeck, L.5
Groopman, J.D.6
-
111
-
-
0026573342
-
Cloning and characterization of a novel CYP3A1 allelic variant: Analysis of CYP3A1 and CYP3A2 sex-hormone-dependent expression reveals that the CYP3A2 gene is regulated by testosterone
-
Ribeiro V, Lechner MC. Cloning and characterization of a novel CYP3A1 allelic variant: analysis of CYP3A1 and CYP3A2 sex-hormone-dependent expression reveals that the CYP3A2 gene is regulated by testosterone. Arch Biochem Biophys 1992;293:147-52.
-
(1992)
Arch Biochem Biophys
, vol.293
, pp. 147-152
-
-
Ribeiro, V.1
Lechner, M.C.2
-
112
-
-
0023943652
-
Lack of bimodality in nifedipine plasma kinetics in a large population of healthy subjects
-
Schellens JHM, Soons PA, Breimer DD. Lack of bimodality in nifedipine plasma kinetics in a large population of healthy subjects. Biochem Pharmacol 1988;37:2507-10.
-
(1988)
Biochem Pharmacol
, vol.37
, pp. 2507-2510
-
-
Schellens, J.H.M.1
Soons, P.A.2
Breimer, D.D.3
-
113
-
-
0001476276
-
Variability in pharmacokinetics and metabolism of nifedipine and other dihydropyrimidine calcium entry blockers
-
Kalow W, red. New York: Pergamon Press
-
Soons PA, Schellens JHM, Breimer DD. Variability in pharmacokinetics and metabolism of nifedipine and other dihydropyrimidine calcium entry blockers. In: Kalow W, red. Pharmacogenetics of drug metabolism. New York: Pergamon Press, 1992:769-89.
-
(1992)
Pharmacogenetics of Drug Metabolism
, pp. 769-789
-
-
Soons, P.A.1
Schellens, J.H.M.2
Breimer, D.D.3
-
114
-
-
0022550688
-
Oxidation of 4-aryl- and 4-alkyl-substituted 2,6-dimethyl-3,5-bis(alkoxycarbonyl)-1,4-dihydropyridines by human liver microsomes and immunochemical evidence for the involvement of a form of cytochrome P-450
-
Bocker RH, Guengerich FP. Oxidation of 4-aryl- and 4-alkyl-substituted 2,6-dimethyl-3,5-bis(alkoxycarbonyl)-1,4-dihydropyridines by human liver microsomes and immunochemical evidence for the involvement of a form of cytochrome P-450. J Med Chem 1986;29:1596-603.
-
(1986)
J Med Chem
, vol.29
, pp. 1596-1603
-
-
Bocker, R.H.1
Guengerich, F.P.2
-
115
-
-
0024373348
-
Oxidation of midazolam and triazolam by human liver cytochrome P450IIIA4
-
Kronbach T, Mathys D, Umeno M, Gonzales FJ, Meyer UA. Oxidation of midazolam and triazolam by human liver cytochrome P450IIIA4. Mol Pharmacol 1989;36:89-96.
-
(1989)
Mol Pharmacol
, vol.36
, pp. 89-96
-
-
Kronbach, T.1
Mathys, D.2
Umeno, M.3
Gonzales, F.J.4
Meyer, U.A.5
-
117
-
-
0023811841
-
No evidence of a genetic polymorphism in the oxidative metabolism of midazolam
-
Kassai A, Toth G, Eichelbaum M, Klotz U. No evidence of a genetic polymorphism in the oxidative metabolism of midazolam. Clin Pharmacokinet 1988;15:319-25.
-
(1988)
Clin Pharmacokinet
, vol.15
, pp. 319-325
-
-
Kassai, A.1
Toth, G.2
Eichelbaum, M.3
Klotz, U.4
-
118
-
-
0027477751
-
A potentially hazardous interaction between erythromycin and midazolam
-
Olkkola KT, Aranko K, Luurila H, Hiller A, Saanivaara L, Himberg JJ, et al. A potentially hazardous interaction between erythromycin and midazolam. Clin Pharmacol Ther 1993;53:298-305.
-
(1993)
Clin Pharmacol Ther
, vol.53
, pp. 298-305
-
-
Olkkola, K.T.1
Aranko, K.2
Luurila, H.3
Hiller, A.4
Saanivaara, L.5
Himberg, J.J.6
-
119
-
-
0028357256
-
Midazolam should be avoided in patients receiving the systemic antimycotics ketoconazole or itraconazole
-
Olkkola K, Backman JT, Neuvonen PJ. Midazolam should be avoided in patients receiving the systemic antimycotics ketoconazole or itraconazole. Clin Pharmacol Ther 1994;55:481-5.
-
(1994)
Clin Pharmacol Ther
, vol.55
, pp. 481-485
-
-
Olkkola, K.1
Backman, J.T.2
Neuvonen, P.J.3
-
120
-
-
0028346064
-
Drug induced torsades de pointes: A possible interaction of terfenadine and erythromycin
-
Biglin KE, Faraon MS, Consyance TD, Lieh-Lai M. Drug induced torsades de pointes: a possible interaction of terfenadine and erythromycin. Ann Pharmacother 1994;28:282.
-
(1994)
Ann Pharmacother
, vol.28
, pp. 282
-
-
Biglin, K.E.1
Faraon, M.S.2
Consyance, T.D.3
Lieh-Lai, M.4
-
121
-
-
0027468346
-
Terfenadine-ketoconazole interaction. Pharmacokinetic and electrocardiographic consequences
-
Honig PK, Wortham DC, Zamani K, Conner DP, Mullin JC, Cantilena LR. Terfenadine-ketoconazole interaction. Pharmacokinetic and electrocardiographic consequences. JAMA 1993;269:1550-2.
-
(1993)
JAMA
, vol.269
, pp. 1550-1552
-
-
Honig, P.K.1
Wortham, D.C.2
Zamani, K.3
Conner, D.P.4
Mullin, J.C.5
Cantilena, L.R.6
-
122
-
-
0027267566
-
Itraconazole prevents terfenadine metabolism and increases risk of torsades de pointes ventricular tachycardia
-
Pohjola-Sintonen S, Viitasalo M, Toivonen L, Neuvonen P. Itraconazole prevents terfenadine metabolism and increases risk of torsades de pointes ventricular tachycardia. Eur J Clin Pharmacol 1993;45:191-3.
-
(1993)
Eur J Clin Pharmacol
, vol.45
, pp. 191-193
-
-
Pohjola-Sintonen, S.1
Viitasalo, M.2
Toivonen, L.3
Neuvonen, P.4
-
123
-
-
0024556650
-
Erythromycin breath test as an assay of glucocorticoid-inducible liver cytochromes P-450: Studies in rats and patients
-
Watkins PB, Murray SA, Winkelman LG, Heuman DM, Wrighton SA, Guzelian PS. Erythromycin breath test as an assay of glucocorticoid-inducible liver cytochromes P-450: studies in rats and patients. J Clin Invest 1989;83:688-97.
-
(1989)
J Clin Invest
, vol.83
, pp. 688-697
-
-
Watkins, P.B.1
Murray, S.A.2
Winkelman, L.G.3
Heuman, D.M.4
Wrighton, S.A.5
Guzelian, P.S.6
-
124
-
-
0026496411
-
Erythromycin breath test predicts oral clearance of cyclosporine in kidney transplant patients
-
Turgeon DK, Normolle DP, Leichtman AB, Annesley TM, Smith DE, Watkins PB. Erythromycin breath test predicts oral clearance of cyclosporine in kidney transplant patients. Clin Pharmacol Ther 1992;52:471-8.
-
(1992)
Clin Pharmacol Ther
, vol.52
, pp. 471-478
-
-
Turgeon, D.K.1
Normolle, D.P.2
Leichtman, A.B.3
Annesley, T.M.4
Smith, D.E.5
Watkins, P.B.6
-
125
-
-
0023620948
-
Clinically significant carbamazepine drug interactions: An overview
-
Pippenger CE. Clinically significant carbamazepine drug interactions: an overview. Epilepsia 1987;28 suppl:S71-6.
-
(1987)
Epilepsia
, vol.28
, Issue.SUPPL.
-
-
Pippenger, C.E.1
-
127
-
-
0024603850
-
Metabolism of cyclosporin A. IV. Purification and identification of the rifampicin inducible human liver cytochrome P-450 (cyclosporin A oxidase) as a product of P450IIIA gene subfamily
-
Combalbert J, Fabre I, Fabre G, Dalet I, Derancourt J, Cano JP, et al. Metabolism of cyclosporin A. IV. Purification and identification of the rifampicin inducible human liver cytochrome P-450 (cyclosporin A oxidase) as a product of P450IIIA gene subfamily. Drug Metab Dispos 1989;17:197-207.
-
(1989)
Drug Metab Dispos
, vol.17
, pp. 197-207
-
-
Combalbert, J.1
Fabre, I.2
Fabre, G.3
Dalet, I.4
Derancourt, J.5
Cano, J.P.6
-
128
-
-
0028286117
-
Pediatric clinical use of the ketoconazole/cyclosporin interaction
-
Berkovitch M, Bitzan M, Matsui D, Finkelstein H, Balfe JW, Koren G. Pediatric clinical use of the ketoconazole/cyclosporin interaction. Pediatr Nephrol 1994;8:492-3.
-
(1994)
Pediatr Nephrol
, vol.8
, pp. 492-493
-
-
Berkovitch, M.1
Bitzan, M.2
Matsui, D.3
Finkelstein, H.4
Balfe, J.W.5
Koren, G.6
-
129
-
-
0028340382
-
The interaction of the calcium channel blockers verapamil and nifedipine with cyclosporin a in pediatric renal transplant patients
-
Crocker JF, Renton KW, LeVatte TL, McLellan DH. The interaction of the calcium channel blockers verapamil and nifedipine with cyclosporin A in pediatric renal transplant patients. Pediatr Nephrol 1994;8:408-11.
-
(1994)
Pediatr Nephrol
, vol.8
, pp. 408-411
-
-
Crocker, J.F.1
Renton, K.W.2
LeVatte, T.L.3
McLellan, D.H.4
-
130
-
-
0025240937
-
Pharmacokinetic interaction between cyclosporin and diltiazem
-
Brockmoller J, Neumayer HH, Wagner K, Weber W, Heinemeyer G, Kewitz H. Pharmacokinetic interaction between cyclosporin and diltiazem. Eur J Clin Pharmacol 1990;38:237-42.
-
(1990)
Eur J Clin Pharmacol
, vol.38
, pp. 237-242
-
-
Brockmoller, J.1
Neumayer, H.H.2
Wagner, K.3
Weber, W.4
Heinemeyer, G.5
Kewitz, H.6
-
131
-
-
0029123393
-
The effects of ketoconazole on the intestinal metabolism and bioavailability of cyclosporine
-
Gomez DY, Wacher VJ, Tomlanovich SJ, Hebert MF, Benet LZ. The effects of ketoconazole on the intestinal metabolism and bioavailability of cyclosporine. Clin Pharmacol Ther 1995;58:15-9.
-
(1995)
Clin Pharmacol Ther
, vol.58
, pp. 15-19
-
-
Gomez, D.Y.1
Wacher, V.J.2
Tomlanovich, S.J.3
Hebert, M.F.4
Benet, L.Z.5
-
132
-
-
0028070642
-
Lansoprazole. A reappraisal of its pharmacodynamic and pharmacokinetic properties, and its therapeutic efficacy in acid-related disorders
-
Spencer CM, Faulds D. Lansoprazole. A reappraisal of its pharmacodynamic and pharmacokinetic properties, and its therapeutic efficacy in acid-related disorders. Drugs 1994;48:404-30.
-
(1994)
Drugs
, vol.48
, pp. 404-430
-
-
Spencer, C.M.1
Faulds, D.2
-
133
-
-
0026799461
-
In vivo evidence that ethosuximide is a substrate for cytochrome P450IIIA
-
Bachman K, Chu CA, Grear V. in vivo evidence that ethosuximide is a substrate for cytochrome P450IIIA. Pharmacology 1992;45:121-8.
-
(1992)
Pharmacology
, vol.45
, pp. 121-128
-
-
Bachman, K.1
Chu, C.A.2
Grear, V.3
-
134
-
-
0027379673
-
Evidence for CYP3A-mediated N-deethylation of amiodarone in human liver microsomal functions
-
Fabre G, Julian B, Saint-Aubert B, Joyeux H, Berger Y. Evidence for CYP3A-mediated N-deethylation of amiodarone in human liver microsomal functions. Drug Metab Dispos 1993;21:978-85.
-
(1993)
Drug Metab Dispos
, vol.21
, pp. 978-985
-
-
Fabre, G.1
Julian, B.2
Saint-Aubert, B.3
Joyeux, H.4
Berger, Y.5
-
135
-
-
0027221052
-
Metabolism of the antimammary cancer antiestrogenic agent tamoxifen. I. Cytochrome P-450-catalyzed N-demethylation and 4-hydroxylation
-
Mani C, Gelboin HV, Park SS, Pearce R, Parkinson A, Kupfer D. Metabolism of the antimammary cancer antiestrogenic agent tamoxifen. I. Cytochrome P-450-catalyzed N-demethylation and 4-hydroxylation. Drug Metab Dispos 1993; 21: 645-656.
-
(1993)
Drug Metab Dispos
, vol.21
, pp. 645-656
-
-
Mani, C.1
Gelboin, H.V.2
Park, S.S.3
Pearce, R.4
Parkinson, A.5
Kupfer, D.6
-
136
-
-
0027369366
-
Differential activation of cyclophosphamide and ifosphamide by cytochromes P-450 2B and 3A in human liver microsomes
-
Chang TK, Weber GF, Crespi CL, Waxman DJ. Differential activation of cyclophosphamide and ifosphamide by cytochromes P-450 2B and 3A in human liver microsomes. Cancer Res 1993;53:5629-37.
-
(1993)
Cancer Res
, vol.53
, pp. 5629-5637
-
-
Chang, T.K.1
Weber, G.F.2
Crespi, C.L.3
Waxman, D.J.4
-
137
-
-
0028177942
-
Cocaine N-demethylation and the metabolism-related hepatotoxicity can be prevented by cytochrome P450 3A inhibitors
-
Pellinen P, Honkakoski P, Stenback F, Niemitz M, Alhava E, Pelkonen O, et al. Cocaine N-demethylation and the metabolism-related hepatotoxicity can be prevented by cytochrome P450 3A inhibitors. Eur J Pharmacol 1994;270:35-43.
-
(1994)
Eur J Pharmacol
, vol.270
, pp. 35-43
-
-
Pellinen, P.1
Honkakoski, P.2
Stenback, F.3
Niemitz, M.4
Alhava, E.5
Pelkonen, O.6
-
138
-
-
0028833680
-
Interaction of triazolam and ketoconazol
-
Greenblatt DJ. Interaction of triazolam and ketoconazol. Lancet 1995;345:191.
-
(1995)
Lancet
, vol.345
, pp. 191
-
-
Greenblatt, D.J.1
-
139
-
-
0027438301
-
Alprazolam pharmacokinetics, metabolism, and plasma levels: Clinical implications
-
Greenblatt DJ, Von Moltke LL, Harmatz JS, Ciraulo DA, Shader RI. Alprazolam pharmacokinetics, metabolism, and plasma levels: clinical implications. J Clin Psychiatry 1993;54 suppl:4-11.
-
(1993)
J Clin Psychiatry
, vol.54
, Issue.SUPPL.
, pp. 4-11
-
-
Greenblatt, D.J.1
Von Moltke, L.L.2
Harmatz, J.S.3
Ciraulo, D.A.4
Shader, R.I.5
-
140
-
-
0029138380
-
Omeprazole and the cytochrome P450 system
-
Petersen KU. Omeprazole and the cytochrome P450 system. Aliment Pharmacol Ther 1995;9:1-9.
-
(1995)
Aliment Pharmacol Ther
, vol.9
, pp. 1-9
-
-
Petersen, K.U.1
-
141
-
-
0026906604
-
Caffeine as a probe for human cytochromes P450: Validation using cDNA-expression, immunoinhibition and microsomal kinetic and inhibitor techniques
-
Tassaneeyakul W, Mohamed Z, Birkett DJ, McManus ME, Veronese ME, Tukey RH, et al. Caffeine as a probe for human cytochromes P450: validation using cDNA-expression, immunoinhibition and microsomal kinetic and inhibitor techniques. Pharmacogenetics 1992;2:173-83.
-
(1992)
Pharmacogenetics
, vol.2
, pp. 173-183
-
-
Tassaneeyakul, W.1
Mohamed, Z.2
Birkett, D.J.3
McManus, M.E.4
Veronese, M.E.5
Tukey, R.H.6
-
142
-
-
0028336794
-
Phenotyping of CYP1A2 in Japanese population by analysis of caffeine urinary metabolites: Absence of mutation prescribing the phenotype in the CYP1A2 gene
-
Nakajima M, Yokoi T, Mizutani M, Shin S, Kadlubar FF, Kamataki T. Phenotyping of CYP1A2 in Japanese population by analysis of caffeine urinary metabolites: absence of mutation prescribing the phenotype in the CYP1A2 gene. Cancer Epidemiol Biomarkers Prev 1994;3:413-21.
-
(1994)
Cancer Epidemiol Biomarkers Prev
, vol.3
, pp. 413-421
-
-
Nakajima, M.1
Yokoi, T.2
Mizutani, M.3
Shin, S.4
Kadlubar, F.F.5
Kamataki, T.6
-
143
-
-
0027225371
-
In vivo evidence that theophylline is metabolized principally by CYP1A in rats
-
Bachmann K, Sanyal G, Potter J, Schavione R, Loch J. in vivo evidence that theophylline is metabolized principally by CYP1A in rats. Pharmacology 1993;47:1-7.
-
(1993)
Pharmacology
, vol.47
, pp. 1-7
-
-
Bachmann, K.1
Sanyal, G.2
Potter, J.3
Schavione, R.4
Loch, J.5
-
144
-
-
0027985726
-
Clozapine disposition covaries with CYP1A2 activity determined by a caffeine test
-
Bertilsson L, Carillo JA, Dahl ML, Llerena A, Alm C, Bondesson U, et al. Clozapine disposition covaries with CYP1A2 activity determined by a caffeine test. Br J Clin Pharmacol 1994;38:471-3.
-
(1994)
Br J Clin Pharmacol
, vol.38
, pp. 471-473
-
-
Bertilsson, L.1
Carillo, J.A.2
Dahl, M.L.3
Llerena, A.4
Alm, C.5
Bondesson, U.6
-
145
-
-
0024468418
-
Dose related plasma-levels of clozapine: Influence of smoking behaviour, sex and age
-
Haring C, Meise U, Humpel C, Saria A, Fleischhacker WW, Hinterhuber H. Dose related plasma-levels of clozapine: influence of smoking behaviour, sex and age. Psychopharmacology 1989;99 suppl:S38-40.
-
(1989)
Psychopharmacology
, vol.99
, Issue.SUPPL.
-
-
Haring, C.1
Meise, U.2
Humpel, C.3
Saria, A.4
Fleischhacker, W.W.5
Hinterhuber, H.6
-
146
-
-
0028930917
-
Metabolisme van clozapine. Een analyse van de variabelen welke het metabolisme van clozapine kunnen beïnvloeden
-
Touw DJ. Metabolisme van clozapine. Een analyse van de variabelen welke het metabolisme van clozapine kunnen beïnvloeden. Pharm Weekbl 1995;130:256-62.
-
(1995)
Pharm Weekbl
, vol.130
, pp. 256-262
-
-
Touw, D.J.1
-
147
-
-
0028318482
-
Fluvoxamine inhibition and carbamazepine induction of the metabolism of clozapine: Evidence from a therapeutic drug monitoring service
-
Jerling M, Lindstrom L, Bondesson U, Bertilsson L. Fluvoxamine inhibition and carbamazepine induction of the metabolism of clozapine: evidence from a therapeutic drug monitoring service. Ther Drug Monit 1994;16:368-74.
-
(1994)
Ther Drug Monit
, vol.16
, pp. 368-374
-
-
Jerling, M.1
Lindstrom, L.2
Bondesson, U.3
Bertilsson, L.4
-
149
-
-
0029860967
-
Disposition of fluvoxamine in humans is determined by the polymorphic CYP2D6 and also by the CYP1A2 activity
-
Carillo JA, Dahl M-L, Svensson J-O, Alm C, Rodriguez I, Bertilsson L Disposition of fluvoxamine in humans is determined by the polymorphic CYP2D6 and also by the CYP1A2 activity. Clin Pharmacol Ther 1996;60:183-90.
-
(1996)
Clin Pharmacol Ther
, vol.60
, pp. 183-190
-
-
Carillo, J.A.1
Dahl, M.-L.2
Svensson, J.-O.3
Alm, C.4
Rodriguez, I.5
Bertilsson, L.6
-
150
-
-
0028826430
-
Urinary excretion of 6-hydroxychlorzoxazone as an index of CYP1E2 activity
-
Dreisbach AW, Ferencz N, Hopkins NE, Fuentes MG, Rege AB, George WJ, et al. Urinary excretion of 6-hydroxychlorzoxazone as an index of CYP1E2 activity. Clin Pharmacol Ther 1995;58:498-505.
-
(1995)
Clin Pharmacol Ther
, vol.58
, pp. 498-505
-
-
Dreisbach, A.W.1
Ferencz, N.2
Hopkins, N.E.3
Fuentes, M.G.4
Rege, A.B.5
George, W.J.6
-
151
-
-
34547386850
-
Drug-drug interactions mediated by induction of metabolism
-
Breimer DD, Merkus FWHM, red. Leiden: Boerhaave committee for postgraduate medical education
-
Breimer DD. Drug-drug interactions mediated by induction of metabolism. In: Breimer DD, Merkus FWHM, red. Drug-drug and drug-food interactions. Leiden: Boerhaave committee for postgraduate medical education, 1991:35-58.
-
(1991)
Drug-drug and Drug-food Interactions
, pp. 35-58
-
-
Breimer, D.D.1
-
153
-
-
0016229336
-
Influence of neuroleptics and benzodiazpines on metabolism of tricyclic antidepressants in man
-
Gram LF, Overo KF, Kirk L. Influence of neuroleptics and benzodiazpines on metabolism of tricyclic antidepressants in man. Am J Psychiatry 1974;131:8.
-
(1974)
Am J Psychiatry
, vol.131
, pp. 8
-
-
Gram, L.F.1
Overo, K.F.2
Kirk, L.3
-
154
-
-
0015515625
-
Drug interaction: Inhibitory effect of neuroleptics on metabolism of tricyclic antidepressants in man
-
Gram LF, Overo KF. Drug interaction: Inhibitory effect of neuroleptics on metabolism of tricyclic antidepressants in man. Br Med J 1972;71:463-5.
-
(1972)
Br Med J
, vol.71
, pp. 463-465
-
-
Gram, L.F.1
Overo, K.F.2
-
155
-
-
0018909799
-
Neuroleptic effect on desipramine steady-state plasma concentrations
-
Nelson JC, Jatlow PI. Neuroleptic effect on desipramine steady-state plasma concentrations. Am J Psychiatry 1980;137:1232-4.
-
(1980)
Am J Psychiatry
, vol.137
, pp. 1232-1234
-
-
Nelson, J.C.1
Jatlow, P.I.2
-
157
-
-
0026630299
-
Metabolisme van clomipramine
-
Touw DJ. Metabolisme van clomipramine. Pharm Weekbl 1992;127:1068-74.
-
(1992)
Pharm Weekbl
, vol.127
, pp. 1068-1074
-
-
Touw, D.J.1
-
158
-
-
0025915325
-
Fluoxetine and norfluoxetine are potent inhibitors of P450IID6 - The source of the sparteine/debrisoquine oxidation polymorphism
-
Brøsen K, Skjelbø E. Fluoxetine and norfluoxetine are potent inhibitors of P450IID6 - the source of the sparteine/debrisoquine oxidation polymorphism. Br J Clin Pharmacol 1991;32:136-7.
-
(1991)
Br J Clin Pharmacol
, vol.32
, pp. 136-137
-
-
Brøsen, K.1
Skjelbø, E.2
-
159
-
-
0028348762
-
Pharmacokinetics of desipramine coadministered with sertraline or fluoxetine
-
Preskorn SH, Alderman J, Chung M, Harrison W, Messig M, Harris S. Pharmacokinetics of desipramine coadministered with sertraline or fluoxetine. J Clin Psychopharmacol 1994;14:90-8.
-
(1994)
J Clin Psychopharmacol
, vol.14
, pp. 90-98
-
-
Preskorn, S.H.1
Alderman, J.2
Chung, M.3
Harrison, W.4
Messig, M.5
Harris, S.6
-
160
-
-
0025746716
-
Extremely long plasma half-life of amitriptyline in a woman with the cytochrome P450IID6 29/29-kilobase wild-type allele - A slowly reversible interaction with fluoxetine
-
Muller N, Brockmoller J, Toots I. Extremely long plasma half-life of amitriptyline in a woman with the cytochrome P450IID6 29/29-kilobase wild-type allele - a slowly reversible interaction with fluoxetine. Ther Drug Monit 1991;13:533-6.
-
(1991)
Ther Drug Monit
, vol.13
, pp. 533-536
-
-
Muller, N.1
Brockmoller, J.2
Toots, I.3
-
163
-
-
0025788860
-
Increased carbamazepine plasma concentration after fluoxetine coadministration
-
Grimsley SR, Jann MW, Carter JG, D'Mello AP, D'Souza MJ. Increased carbamazepine plasma concentration after fluoxetine coadministration. Clin Pharmacol Ther 1991;50:10-5.
-
(1991)
Clin Pharmacol Ther
, vol.50
, pp. 10-15
-
-
Grimsley, S.R.1
Jann, M.W.2
Carter, J.G.3
D'Mello, A.P.4
D'Souza, M.J.5
-
166
-
-
0028120975
-
Probable metabolic interaction between methadone and fluvoxamine in addict patients
-
Bertschy G, Baumann P, Eap CB, Baettig D. Probable metabolic interaction between methadone and fluvoxamine in addict patients. Ther Drug Monit 1994;16:42-5.
-
(1994)
Ther Drug Monit
, vol.16
, pp. 42-45
-
-
Bertschy, G.1
Baumann, P.2
Eap, C.B.3
Baettig, D.4
-
167
-
-
0026041851
-
Toxic interaction between fluvoxamine and sustained release theophylline in an 11-year-old boy
-
Sperber AD. Toxic interaction between fluvoxamine and sustained release theophylline in an 11-year-old boy. Drug Safety 1991;6:460-2.
-
(1991)
Drug Safety
, vol.6
, pp. 460-462
-
-
Sperber, A.D.1
-
168
-
-
0028143388
-
Toxic effects of theophylline caused by fluvoxamine
-
Van den Brekel AM, Harrington L. Toxic effects of theophylline caused by fluvoxamine. Can Med Assoc J 1994;151:1289-90.
-
(1994)
Can Med Assoc J
, vol.151
, pp. 1289-1290
-
-
Van Den Brekel, A.M.1
Harrington, L.2
-
169
-
-
0026334963
-
Interaction between carbamazepine and fluvoxamine
-
Unsorg FJ, Lanczik M. Interaction between carbamazepine and fluvoxamine. Acta Psychiatr Scand 1991;84:583-4.
-
(1991)
Acta Psychiatr Scand
, vol.84
, pp. 583-584
-
-
Unsorg, F.J.1
Lanczik, M.2
-
170
-
-
0028150994
-
Coadministration of fluvoxamine increases serum concentrations of haloperidol
-
Daniel DG, Randolph C, Jasskin G, Handel S, Williams T, Abi-Dargham A, et al. Coadministration of fluvoxamine increases serum concentrations of haloperidol. J Clin Psychopharmacol 1994;14:340-3.
-
(1994)
J Clin Psychopharmacol
, vol.14
, pp. 340-343
-
-
Daniel, D.G.1
Randolph, C.2
Jasskin, G.3
Handel, S.4
Williams, T.5
Abi-Dargham, A.6
-
171
-
-
0028080304
-
Inhibition of diazepam metabolism by fluvoxamine: A pharmacokinetic study in normal volunteers
-
Perucca E, Gatti G, Cipolla G, Spina E, Barel S, Soback S, et al. Inhibition of diazepam metabolism by fluvoxamine: a pharmacokinetic study in normal volunteers. Clin Pharmacol Ther 1994;56:471-6.
-
(1994)
Clin Pharmacol Ther
, vol.56
, pp. 471-476
-
-
Perucca, E.1
Gatti, G.2
Cipolla, G.3
Spina, E.4
Barel, S.5
Soback, S.6
-
172
-
-
0026019728
-
Fluvoxamine-tricyclic antidepressant interaction: An accidental finding
-
Bertschy G, Vandel S, Allers G, Volmat R. Fluvoxamine-tricyclic antidepressant interaction: an accidental finding [brief]. Eur J Clin Pharmacol 1991;40:119-20.
-
(1991)
Eur J Clin Pharmacol
, vol.40
, pp. 119-120
-
-
Bertschy, G.1
Vandel, S.2
Allers, G.3
Volmat, R.4
-
173
-
-
0027254118
-
Effect of fluvoxamine on the pharmacokinetics of imipramine and desipramine in healthy subjects
-
Spina E, Pollicino AM, Avenoso A, Campo GM, Perucca E, Caputi AP. Effect of fluvoxamine on the pharmacokinetics of imipramine and desipramine in healthy subjects. Ther Drug Monit 1993;15:243-6.
-
(1993)
Ther Drug Monit
, vol.15
, pp. 243-246
-
-
Spina, E.1
Pollicino, A.M.2
Avenoso, A.3
Campo, G.M.4
Perucca, E.5
Caputi, A.P.6
-
174
-
-
0028088621
-
Inhibition of hepatic P-450 isoenzymes by serotonin selective reuptake inhibitors: In vitro and in vivo findings and their implications for patient care
-
Preskorn SH, Magnus RD. Inhibition of hepatic P-450 isoenzymes by
-
(1994)
Psychopharmacol Bull
, vol.30
, pp. 251-259
-
-
Preskorn, S.H.1
Magnus, R.D.2
-
175
-
-
0027489085
-
An interaction of sertraline and desipramine
-
Barros J, Asnis G. An interaction of sertraline and desipramine. Am J Psychiatry 1993;150:1751.
-
(1993)
Am J Psychiatry
, vol.150
, pp. 1751
-
-
Barros, J.1
Asnis, G.2
-
176
-
-
0027191034
-
Interactions between sertraline and tricyclic antidepressants
-
Lydiard RB, Anton RF, Cunningham T. Interactions between sertraline and tricyclic antidepressants. Am J Psychiatry 1993;150:1125-6.
-
(1993)
Am J Psychiatry
, vol.150
, pp. 1125-1126
-
-
Lydiard, R.B.1
Anton, R.F.2
Cunningham, T.3
-
177
-
-
0027163866
-
Moclobemide treatment causes a substantial rise in the sparteine metabolic ratio
-
Gram LF, Brøsen K. Moclobemide treatment causes a substantial rise in the sparteine metabolic ratio. Br J Clin Pharmacol 1993;35:649-52.
-
(1993)
Br J Clin Pharmacol
, vol.35
, pp. 649-652
-
-
Gram, L.F.1
Brøsen, K.2
-
178
-
-
0028115901
-
The use of therapeutic drug monitoring data to document kinetic drug interactions: An example with amitriptyline and nortriptyline
-
Jerling M, Bertilsson L, Sjøqvist F. The use of therapeutic drug monitoring data to document kinetic drug interactions: an example with amitriptyline and nortriptyline. Ther Drug Monit 1994;16:1-12.
-
(1994)
Ther Drug Monit
, vol.16
, pp. 1-12
-
-
Jerling, M.1
Bertilsson, L.2
Sjøqvist, F.3
-
179
-
-
0027162910
-
Concomitant intake of nortriptyline and carbamazepine
-
Brøsen K, Kragh-Sorensen P. Concomitant intake of nortriptyline and carbamazepine. Ther Drug Monit 1993;15:258-60.
-
(1993)
Ther Drug Monit
, vol.15
, pp. 258-260
-
-
Brøsen, K.1
Kragh-Sorensen, P.2
-
180
-
-
0029964624
-
Effects of carbamazepine coadministration on plasma concentrations of trazodone and its active metabolite, m-chlorophenylpiperazine
-
Otani K, Ishida M, Kaneko S, Mihara K, Okhubo T, Osanai T, et al. Effects of carbamazepine coadministration on plasma concentrations of trazodone and its active metabolite, m-chlorophenylpiperazine. Ther Drug Monit 1996;18:164-7.
-
(1996)
Ther Drug Monit
, vol.18
, pp. 164-167
-
-
Otani, K.1
Ishida, M.2
Kaneko, S.3
Mihara, K.4
Okhubo, T.5
Osanai, T.6
-
181
-
-
0030040670
-
Phenobarbital induces the 2-hydroxylation of desipramine
-
Spina E, Avenoso A, Campo GM, Caputi AP, Perucca E. Phenobarbital induces the 2-hydroxylation of desipramine. Ther Drug Monit 1996;18:60-4.
-
(1996)
Ther Drug Monit
, vol.18
, pp. 60-64
-
-
Spina, E.1
Avenoso, A.2
Campo, G.M.3
Caputi, A.P.4
Perucca, E.5
-
182
-
-
0025955418
-
Differential effects of quinidine on the disposition of nifedipine, sparteine, and mephenytoin in humans
-
Schellens JHM, Ghabrial H, Van der Wart HHF, Bakker EN, Wilkinson GR, Breimer DD. Differential effects of quinidine on the disposition of nifedipine, sparteine, and mephenytoin in humans. Clin Pharmacol Ther 1991;50:520-8.
-
(1991)
Clin Pharmacol Ther
, vol.50
, pp. 520-528
-
-
Schellens, J.H.M.1
Ghabrial, H.2
Van Der Wart, H.H.F.3
Bakker, E.N.4
Wilkinson, G.R.5
Breimer, D.D.6
-
184
-
-
0024573529
-
The influence of cimetidine on debrisoquine 4-hydroxylation in extensive metabolizers
-
Philip PA, James CA, Rogers HJ. The influence of cimetidine on debrisoquine 4-hydroxylation in extensive metabolizers. Eur J Clin Pharmacol 1989;36:319-21.
-
(1989)
Eur J Clin Pharmacol
, vol.36
, pp. 319-321
-
-
Philip, P.A.1
James, C.A.2
Rogers, H.J.3
-
185
-
-
0025807980
-
2-receptor antagonists
-
2-receptor antagonists. Am Pharm 1991;31:29-35.
-
(1991)
Am Pharm
, vol.31
, pp. 29-35
-
-
Campagna, K.D.1
-
186
-
-
0025721063
-
Clinical implications of drug interactions with the cytochrome P-450 enzyme system associated with omeprazole
-
Humphries TJ. Clinical implications of drug interactions with the cytochrome P-450 enzyme system associated with omeprazole. Dig Dis Sci 1991;36:1665-9.
-
(1991)
Dig Dis Sci
, vol.36
, pp. 1665-1669
-
-
Humphries, T.J.1
-
188
-
-
0027972607
-
Diltiazem treatment impairs theophylline elimination in patients with bronchospastic airway disease
-
Soto J, Sacristan JA, Alsar MJ. Diltiazem treatment impairs theophylline elimination in patients with bronchospastic airway disease. Ther Drug Monit 1994;16:49-52.
-
(1994)
Ther Drug Monit
, vol.16
, pp. 49-52
-
-
Soto, J.1
Sacristan, J.A.2
Alsar, M.J.3
-
189
-
-
0019215945
-
Pharmacokinetic interaction between propranolol and chlorpromazine in schizophrenic patients
-
Peet M, Middlemiss DN, Yates RA. Pharmacokinetic interaction between propranolol and chlorpromazine in schizophrenic patients. Lancet 1980;2:978.
-
(1980)
Lancet
, vol.2
, pp. 978
-
-
Peet, M.1
Middlemiss, D.N.2
Yates, R.A.3
-
191
-
-
0021347157
-
Effect of propranolol on maprotiline clearance
-
Tollefson G, Lesar T. Effect of propranolol on maprotiline clearance. Am J Psychiatry 1984;141:148-9.
-
(1984)
Am J Psychiatry
, vol.141
, pp. 148-149
-
-
Tollefson, G.1
Lesar, T.2
-
192
-
-
0017697831
-
Propranolol as an adjunct to the treatment of schizophrenia
-
Yorkston NJ, Zaki SA, Pitcher DR, Gruzelier JH, Hollander D, Sergeant HGS. Propranolol as an adjunct to the treatment of schizophrenia. Lancet 1977;2:575-8.
-
(1977)
Lancet
, vol.2
, pp. 575-578
-
-
Yorkston, N.J.1
Zaki, S.A.2
Pitcher, D.R.3
Gruzelier, J.H.4
Hollander, D.5
Sergeant, H.G.S.6
-
193
-
-
0029782647
-
Erythromycin-felodipine interaction: Magnitude, mechanism, and comparison with grapefruit juice
-
Bailey DG, Bend JR, Arnold MO, Tran LT, Spence JD. Erythromycin-felodipine interaction: magnitude, mechanism, and comparison with grapefruit juice. Clin Pharmacol Ther 1996;60:25-33.
-
(1996)
Clin Pharmacol Ther
, vol.60
, pp. 25-33
-
-
Bailey, D.G.1
Bend, J.R.2
Arnold, M.O.3
Tran, L.T.4
Spence, J.D.5
-
194
-
-
0029906503
-
Drug interactions predisposing to ventricular arrhythmias
-
Drug interactions predisposing to ventricular arrhythmias. WHO Drug Information 1996;10:85-6.
-
(1996)
WHO Drug Information
, vol.10
, pp. 85-86
-
-
-
195
-
-
0028865688
-
Azithromycine and terfenadine: Lack of drug interaction
-
Harris S, Hilligoss DM, Colangelo PM, Eller M, Okerholm R. Azithromycine and terfenadine: Lack of drug interaction. Clin Pharmacol Ther 1995;48:310-5.
-
(1995)
Clin Pharmacol Ther
, vol.48
, pp. 310-315
-
-
Harris, S.1
Hilligoss, D.M.2
Colangelo, P.M.3
Eller, M.4
Okerholm, R.5
-
196
-
-
0028357256
-
Midazolam should be avoided in patients receiving the systemic antimycotics ketoconazole or itraconazole
-
Olkkola KT, Backman JT, Neuvonen PJ. Midazolam should be avoided in patients receiving the systemic antimycotics ketoconazole or itraconazole. Clin Pharmacol Ther 1994;55:481-5.
-
(1994)
Clin Pharmacol Ther
, vol.55
, pp. 481-485
-
-
Olkkola, K.T.1
Backman, J.T.2
Neuvonen, P.J.3
-
197
-
-
0027163604
-
Inhibition and induction of cytochrome P4502E1-catalyzed oxidation by isoniazid in humans
-
Zand R, Nelson SD, Slattery JT, Thummel KE, Kalhorn TF, Adams SP, et al. Inhibition and induction of cytochrome P4502E1-catalyzed oxidation by isoniazid in humans. Clin Pharmacol Ther 1993;54:142-9.
-
(1993)
Clin Pharmacol Ther
, vol.54
, pp. 142-149
-
-
Zand, R.1
Nelson, S.D.2
Slattery, J.T.3
Thummel, K.E.4
Kalhorn, T.F.5
Adams, S.P.6
-
198
-
-
0025027886
-
Severe acetaminophen toxicity in a patient receiving isoniazid
-
Murphy R, Swartz R, Watkins PB. Severe acetaminophen toxicity in a patient receiving isoniazid. Ann Intern Med 1990;113:799-800.
-
(1990)
Ann Intern Med
, vol.113
, pp. 799-800
-
-
Murphy, R.1
Swartz, R.2
Watkins, P.B.3
-
199
-
-
0027414911
-
Pharmacokinetics of gyrase inhibitors, part 2: Renal and hepatic elimination pathways and drug interactions
-
Sorgel F, Kinzig M. Pharmacokinetics of gyrase inhibitors, part 2: Renal and hepatic elimination pathways and drug interactions. Am J Med 1993;94 suppl 3A:56S-69S.
-
(1993)
Am J Med
, vol.94
, Issue.SUPPL. 3A
-
-
Sorgel, F.1
Kinzig, M.2
-
200
-
-
0028856444
-
Norfloxacin interferes with cyclosporine disposition in pediatric patients undergoing renal transplantation
-
McLellan RA, Drobitch RK, McLellan DH, Acott PD, Crocker JFS, Renton KW. Norfloxacin interferes with cyclosporine disposition in pediatric patients undergoing renal transplantation. Clin Pharmacol Ther 1995;58:322-7.
-
(1995)
Clin Pharmacol Ther
, vol.58
, pp. 322-327
-
-
McLellan, R.A.1
Drobitch, R.K.2
McLellan, D.H.3
Acott, P.D.4
Crocker, J.F.S.5
Renton, K.W.6
-
201
-
-
0027159323
-
Single-dose disulfiram inhibition of chlorzoxazone metabolism: A clinical probe for P450 2E1
-
Kharasch ED, Thummel KE, Mhyre J, Lillibridge JH. Single-dose disulfiram inhibition of chlorzoxazone metabolism: a clinical probe for P450 2E1. Clin Pharmacol Ther 1993;52:231-8.
-
(1993)
Clin Pharmacol Ther
, vol.52
, pp. 231-238
-
-
Kharasch, E.D.1
Thummel, K.E.2
Mhyre, J.3
Lillibridge, J.H.4
-
202
-
-
0028846142
-
In vivo inhibition profile of cytochrome P450TB (CYP2C9) by (±)-fluvastatin
-
Transon C, Leemann T, Vogt N, Dayer P. in vivo inhibition profile of cytochrome P450TB (CYP2C9) by (±)-fluvastatin. Clin Pharmacol Ther 1995;58:412-7.
-
(1995)
Clin Pharmacol Ther
, vol.58
, pp. 412-417
-
-
Transon, C.1
Leemann, T.2
Vogt, N.3
Dayer, P.4
-
203
-
-
0029803724
-
Klinisch relevante geneesmiddelinteracties met antiretrovirale middelen
-
Burger DM, Hoetelmans RMW. Klinisch relevante geneesmiddelinteracties met antiretrovirale middelen. Pharm Weekbl 1996;131:1232-4.
-
(1996)
Pharm Weekbl
, vol.131
, pp. 1232-1234
-
-
Burger, D.M.1
Hoetelmans, R.M.W.2
-
204
-
-
34547385075
-
Antiretrovirale middelen
-
's-Gravenhage: KNMP
-
Antiretrovirale middelen. In: Informatorium Medicamentorum. 1977. 's-Gravenhage: KNMP 1997:300-5.
-
(1997)
Informatorium Medicamentorum. 1977
, pp. 300-305
-
-
-
206
-
-
0030068752
-
Rifampicin drastically reduces plasma concentrations and effects of oral midazolam
-
Backman JT, Olkkola KT, Neuvonen PJ. Rifampicin drastically reduces plasma concentrations and effects of oral midazolam. Clin Pharmacol Ther 1996;59:7-13.
-
(1996)
Clin Pharmacol Ther
, vol.59
, pp. 7-13
-
-
Backman, J.T.1
Olkkola, K.T.2
Neuvonen, P.J.3
-
207
-
-
0026099498
-
Interaction of citrus juices with felodipine and nifedipine
-
Bailey DG, Spence JD, Munzo C, Arnold JMO. Interaction of citrus juices with felodipine and nifedipine. Lancet 1991;337:268-9.
-
(1991)
Lancet
, vol.337
, pp. 268-269
-
-
Bailey, D.G.1
Spence, J.D.2
Munzo, C.3
Arnold, J.M.O.4
-
208
-
-
0025952282
-
Grapefruit juice and cimetidine inhibit stereoselective metabolism of nitrendipine in humans
-
Soons PA, Vogels BAPM, Roosemalen MCM, Schoemaker HC, Uchida E, Edgar B, et al. Grapefruit juice and cimetidine inhibit stereoselective metabolism of nitrendipine in humans. Clin Pharmacol Ther 1991;50:394-403.
-
(1991)
Clin Pharmacol Ther
, vol.50
, pp. 394-403
-
-
Soons, P.A.1
Vogels, B.A.P.M.2
Roosemalen, M.C.M.3
Schoemaker, H.C.4
Uchida, E.5
Edgar, B.6
-
209
-
-
0028963036
-
Effect of grapefruit juice on blood cyclosporin concentration
-
Yee GC, Stanley DL, Pessa LJ, Dalla Costa T, Beltz SE, Ruiz J, et al. Effect of grapefruit juice on blood cyclosporin concentration. Lancet 1995;345:955-6.
-
(1995)
Lancet
, vol.345
, pp. 955-956
-
-
Yee, G.C.1
Stanley, D.L.2
Pessa, L.J.3
Dalla Costa, T.4
Beltz, S.E.5
Ruiz, J.6
-
210
-
-
0029150833
-
Interaction between grapefruit juice and midazolam in humans
-
Kupferschmidt HHT, Ha HR, Ziegler WH, Meier PJ, Krahlenbuhl S. Interaction between grapefruit juice and midazolam in humans. Clin Pharmacol Ther 1995;58:20-8.
-
(1995)
Clin Pharmacol Ther
, vol.58
, pp. 20-28
-
-
Kupferschmidt, H.H.T.1
Ha, H.R.2
Ziegler, W.H.3
Meier, P.J.4
Krahlenbuhl, S.5
-
211
-
-
0029101508
-
Plasma concentrations of triazolam are increased by concomitant ingestion of grapefruit juice
-
Hukkinen SK, Varhe A, Olkkola KT, Neuvonen PJ. Plasma concentrations of triazolam are increased by concomitant ingestion of grapefruit juice. Clin Pharmacol Ther 1995;58:127-31.
-
(1995)
Clin Pharmacol Ther
, vol.58
, pp. 127-131
-
-
Hukkinen, S.K.1
Varhe, A.2
Olkkola, K.T.3
Neuvonen, P.J.4
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