Effectiveness of low-dose ASA in prevention of secondary ischemic stroke, the asa study group in Taiwan

Thrombosis Research

Volumn 87, Issue 2, 1997, Pages 215-224

  Lee, Ti Kai ^a   Chan, Kin Wei A ^a   Huang, Zei Shung ^a   Ng, Sien Kiat ^a   Lin, Ruey Tay ^a   Po, Helen L ^a   Yuan, Rey Yue ^a   Lai, Ming Liang ^a   Chang, Tso Wen ^a   Yan, Sui Hing ^a   Deng, Jong Chyou ^a   Liu, Lu Han ^a   Lee, Kei Yee ^a   Lie, Sian King ^a   Sung, Shing Ming ^a   Hu, Han Hwa ^a  

^a NONE

Author keywords

Aspirin; Chinese; Clinical trials; Ischemic; Stroke; Stroke prevention

Indexed keywords

ACETYLSALICYLIC ACID; PROSTACYCLIN; THROMBOXANE A2;

ADULT; AGED; ARTICLE; BRAIN INFARCTION; BRAIN ISCHEMIA; CEREBROVASCULAR DISEASE; CHINESE; CLINICAL TRIAL; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DAILY LIFE ACTIVITY; DIGESTIVE SYSTEM HEMORRHAGE; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG EFFICACY; EPIGASTRIC PAIN; FEMALE; HEARTBURN; HEMATURIA; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SKIN ALLERGY; STOMACH ULCER; STROKE; TAIWAN;

AGED; ASPIRIN; BRAIN ISCHEMIA; DOUBLE-BLIND METHOD; FEMALE; HUMANS; MALE; MIDDLE AGED; PLATELET AGGREGATION INHIBITORS; RECURRENCE;

EID: 0030740971     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0049-3848(97)00121-7     Document Type: Article

References (30)

1. MEYER JS Summary of the international round table conference on platelet aggregation in the pathogenesis of cerebrovascular disorders. Stoke. 6:1975;239-244.
2. COUCH JR, HASSANEIN RS Platelet aggregation, stroke and transient ischemic attack in middle aged and elderly patients. Neurology. 26:1976;888-895.
3. DOUGHERTY JH JR., LEVY DE, WEKSLER BB Platelet activation in acute cerebral ischemia. Lancet. 1:1977;821-824.
4. FIELDS WS, LEMARK NA, FRANKOWSKI RF, HARDY RJ Controlled trial of aspirin in cerebral ischemia. Stroke. 8:1977;301-314.
5. THE CANADIAN COOPERATIVE STUDY GROUP: A randomized trial of aspirin and sulfinpyrazone in threatened stroke. N Engl J Med 299, 53-59, 1978.
6. NISHIMURA H, NARITOMI H, IWAMOTO Y, TACHIBANA H, SUGITA M In vivo elevation of antiplatelet agents in gerbil model of carotid artery thrombosis. Stroke. 27:1996;1099-1103.
7. PATRONO C, ROTH GJ Aspirin in cerebrovascular disease: How strong is the case for a different dosing regimen? Stroke. 27:1996;756-760.
8. PARIS J, FOURNAU P, GRANERO M, VIENS C Antithrombotic effect of very low doses of acetylsalicylic acid in rats. Thromb Res. 29:1983;313-321.
9. THIESSEN JJ Aspirin plasma concentration and effects. Thromb Res Supple. IV:1983;105-111.
10. LEE TK, CHEN YC, LIEN IN, LIN MC, HUANG ZS Inhibitory effect of acetylsalicylic acid on platelet function in patients with completed stroke or reversible ischemic neurologic deficit. Stroke. 19:1988;566-570.
11. THE SALT COLLABORATIVE GROUP: Swedish aspirin low-dose trial (SALT) of 75 mg aspirin as secondary prophylaxis after cerebrovascular ischemic events. Lancet 338, 1345-1349, 1991.
12. THE DUTCH TIA TRIAL STUDY GROUP: A comparison of two doses of aspirin (30 mg vs. 283 mg a day) in patients after a transient ischemic attack of minor ischemic stroke. N Engl J Med 325, 1261-1266, 1991.
13. LINDBLAD B, PERSSON NH, TAKOLANDER R, BERGQVIST D Dose low-dose acetylsalicyclic acid prevent stroke after carotid surgery? A double-blind, placebo-controlled randomized trial. Stroke. 24:1993;1125-1128.
14. THE UNITED KINGDOM TRANSIENT ISCHEMIC ATTACK (UK-TIA) ASPIRIN TRIAL:FINAL RESULTS. J Neurol Neurosurg Psychiatry 54: 1044-1054, 1991.
15. ANTIPLATELET TRIALISTS COLLABORATION: Secondary prevention of vascular disease by prolonged antiplatelet treatment. Br Med J 296, 320-331, 1988.
16. COCHRAN WG, COX GN: Experimental Designs. 2nd ed. New York, N.Y., John Wiley and Sons, Inc. 1957.
17. KAPLAN EL, MEIER P Nonparametric estimation from incomplete observations. J Am Statist Assoc. 53:1958;457-481.
18. ALTMAN DG: Practical statistics for medical research. Chapman and Hall London, 365-393, 1991.
19. COX DR Regression models and life tables. J Roy Statist Soc. 34B:1972;187-220.
20. LEE TK, LIEN IN, RYU SJ, LEE KY, HU HH, TCHEN PH, CHEN CJ, WU SC, CHEN YC Secondary prevention of ischemic stroke with low dose acetylsalicylic acid. J Formosan Med Assoc. 89:1990;635-644.
21. GRAHAM DY, SMITH JL, SPJUT HJ, TORRES E Gastric adaptation. Studies in human during continuous aspirin administration. Gastroenterology. 95:1988;327-333.
22. REHDERS K, SIMROK R, SPAHN H, MUTSCHLER E, BREDDIN HK Plasma salicylate levels and platelet function after acute and chronic administration of slow-release acetylsalicylic acid (Monobeltin). Eur J Clin Pharmacol. 27:1985;683-687.
23. MOHRI H, OHKUBO T Single-dose effect of enteric-coated aspirin on platelet function and thromboxane generation in middle-aged men. Ann Pharmacother. 27:1993;405-410.
24. JASZEWSKI R Frequency of gastroduodenal lesions in asymptomatic patients on chronic aspirin or nonsteroidal anti-inflammatory drug therapy. J Clin Gastroenterol. 12:1990;10-13.
25. GOLDSTEIN LB, BONITO AJ, METCHAR DB, DUNCAN PW, DEFRIESE GH, ODDONE EZ, PAUL JE, AKIN DR, SAMSA GP US national survey of Physician practices for the secondary and tertiary prevention of ischemic stroke, design, service availability, and common practices. Stroke. 26:1995;1607-1615.
26. BARNETT HJM, KASTE M, MELDRUM H, ELIASZIW M Aspirin dose in stroke prevention. Beautiful hypothesis slain by ugly facts. Stoke. 27:1996;588-592.
27. HART RG, HARRISON MJG Aspirin wars, the optimal dose of aspirin to prevent stroke. Stroke. 27:1996;585-587.
28. DYKEN ML, BARNETT HJM, EASTON JD, FIELDS WS, FUSTER V, HACHINSKI V, NORRIS JW, SHERMAN DG Low dose aspirin and stroke: "It ain't necessarily so" Stroke. 23:1992;1395-1399.
29. HAWIGER J Adhesive interaction of platelets. Ann Med. 21:1989;23-30.
30. RAO GHR, WHITE JG Role of arachidonic acid metabolism in human platelet activation and irreversible aggregation. Am J Hematol. 19:1985;339-347.