Interferon immunogenicity: Preclinical evaluation of interferon-α2a

Journal of Interferon and Cytokine Research

Volumn 17, Issue SUPPL. 1, 1997, Pages

  Palleroni, Alicia V ^a  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA2 INTERFERON; ALPHA2A INTERFERON; ALPHA2B INTERFERON; ALPHA2C INTERFERON; INTERFERON; INTERFERON ANTIBODY; NEUTRALIZING ANTIBODY; RECOMBINANT ALPHA2A INTERFERON; RECOMBINANT ALPHA2B INTERFERON;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ANTIBODY TITER; CONTROLLED STUDY; DRUG ANTIGENICITY; HUMAN; HUMAN CELL; IMMUNOGENICITY; INTRAMUSCULAR DRUG ADMINISTRATION; INTRAPERITONEAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVIEW; SUBCUTANEOUS DRUG ADMINISTRATION; T LYMPHOCYTE;

AMINO ACID SEQUENCE; ANIMALS; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; GENES; HUMANS; INTERFERON ALFA-2A; INTERFERON ALFA-2B; INTERFERON-BETA; LYMPHOCYTE ACTIVATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MICE; MICE, INBRED STRAINS; MICE, TRANSGENIC; PEPTIDES; PROTEIN BINDING; STRUCTURE-ACTIVITY RELATIONSHIP; T-LYMPHOCYTES;

ANIMALIA; MUS MUSCULUS;

EID: 0030740864     PISSN: 10799907     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (3)

1. MOGENSEN, K.E., DAUBAS, P.H., GRESSER. I., SERENI, D., and VARET, B. (1981). Patients with circulating antibodies to α-interferon. Lancet 2, 1227-1228.
2. TROWN, P.W., KRAMER, M.J., DENNIN, R.A. JR., CONNELL, E.V., PALLERONI, A.V., QUESADA, J., and GUTTERMAN, J.U. (1983). Antibodies to human leukocyte interferons in cancer patients. Lancet 1, 81-84.
3. SPEIGEL, J., SPICEHANDLER, J.R., JACOBS. S.L., and ODEN, E.M. (1986). Low incidence.of serum neutralizing factors in patients receiving recombinant alpha 2b interferon (Intron®) Am. J. Med. 80, 223-228.