Fertility after chemotherapy for testicular germ cell cancer

Fertility and Sterility

Volumn 68, Issue 1, 1997, Pages 1-5

  Pont, Jörg ^a,b   Albrecht, Walter ^a  

^a Neurologische Abteilung des Kaiser Franz Josef Spitals   (Austria)

^b KAISER FRANZ JOSEF HOSPITAL   (Austria)

Author keywords

Chemotherapy; Cisplatin; Fertility; Spermatogonial damage; Testicular cancer

Indexed keywords

ANTINEOPLASTIC AGENT; ANTINEOPLASTIC ANTIMETABOLITE; BLEOMYCIN; CHLORAMBUCIL; CISPLATIN; CYCLOPHOSPHAMIDE; DACARBAZINE; ETOPOSIDE; FOLLITROPIN; LUTEINIZING HORMONE; VINBLASTINE; VINCA ALKALOID;

AZOOSPERMIA; CRYOPRESERVATION; GERM CELL TUMOR; HUMAN; MALE; MALE FERTILITY; OLIGOSPERMIA; PRIORITY JOURNAL; REPRODUCTIVE TOXICITY; REVIEW; RISK ASSESSMENT; SPERM PRESERVATION;

EID: 0030740646     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0015-0282(97)81465-3     Document Type: Article

References (45)

1. Berthelsen JG. Testicular cancer and fertility. Int J Androl 1987; 10:371-80.
2. Fossa SD, Aass N, Molne K. Is routine pre-treatment cryo-preservation of semen worthwhile in the management of patients with testicular cancer? Br J Urol 1989;64:524-9.
3. Hansen SW, Berthelsen JG, van der Maase H. Long-term fertility and Leydig cell function in patients treated for germ cell cancer with cisplatin, vinblastine, and bleomycin versus surveillance. J Clin Oncol 1990;8:1695-8.
4. Hansen PV, Glavind K, Panduro J, Pedersen M. Paternity in patients with testicular germ cell cancer: pretreatment and post-treatment findings. Eur J Cancer 1991;27:1385-9.
5. Foster RS, Benett R, Bihrle R, Donohue JP. A preliminary report: postoperative fertility assessment in nerve-sparing RPLND patients. Eur Urol 1993;23:165-8.
6. Pont J, Albrecht W, Postner G, Sellner F, Angel K, Höltl W. Adjuvant chemotherapy for high-risk clinical stage I nonseminomatous testicular germ cell cancer: long term results of a prospective study. J Clin Oncol 1996; 14:441-8.
7. Liu DY, Baker HJ. Tests of human sperm function and fertilization in vitro. Fertil Steril 1992;58:465-83.
8. Meistrich ML. Quantitative correlation between testicular stem cell survival, sperm production and fertility in the mouse after treatment with different cytotoxic agents. J Androl 1982;3:58-68.
9. Meistrich ML. Relationship between spermatogonal stem cell survival and testis function after cytotoxic therapy. Br J Cancer 1986;3(Suppl VII):89-101.
10. Viviani S, Ragni G, Santoro A, Perotti L, Caccomo E, Negretti E, et al. Testicular dysfunction in Hodgkin's disease before and after treatment. Eur J Cancer 1991;27:1389-92.
11. Meistrich ML, Wilson MS, Brown BW, Da Cunha MF, Lipshultz LI. Impact of cyclophosphamide on long term reduction in sperm count in men treated with combination chemotherapy for Ewing and soft tissue sarcomas. Cancer 1992; 70: 2703-12.
12. Meistrich ML, Chawla SP, Da Cunha MF, Johnson SL, Plager C, Papadopoulos NE, et al. Recovery of sperm production after chemotherapy for osteosarcoma. Cancer 1989;63:2115-23.
13. Scheiber K, Bartsch G. Exocrine and endocrine function in patients with testicular tumors. In: Khoury S, et al., eds. Testicular cancer. New York: Alan Liss, 1985:715-25.
14. Carroll PR, Whitmore WF, Jr, Herr HW. Endocrine and exocrine profiles of men with testicular tumors before orchiectomy. J Urol 1987; 137:420-3.
15. Jewett MAS, Thachil JV, Harris JF. Exocrine function of testis with germinal testicular tumor. Br Med J 1983;286:1849-53.
16. Fritz K, Weissbach L. Sperm parameters and ejaculation before and after operative treatment of patients with germ cell testicular cancer. Fertil Steril 1985;43:451-5.
17. Horwich A, Nicholls EJ, Hendry WF. Seminal analysis after orchiectomy in stage I teratoma. Br J Urol 1988;62:79-83.
18. Nijman JM, Schraffordt Koops H, Kremer J. Fertility and hormonal function in patients with a non-seminomatous tumor of the testis. Arch Androl 1985; 14:239-43.
19. Hansen PV, Trykker H, Andersen J. Germ cell function and hormonal status in patients with testicular cancer. Cancer 1989;64:956-61.
20. Drasga RE, Einhorn LH, Williams SD, Partel DN, Stevens EE. Fertility after chemotherapy for testicular cancer. J Clin Oncol 1983; 1:179-83.
21. Dearnaley DP, Horwich A, A'Hern R, Nicholls J, Jay G, Hendry WF, et al. Combination chemotherapy with bleomycin, etoposide, and cisplatin (BEP) for metastatic testicular teratoma: long term follow-up. Eur J Cancer 1991; 27:684-91.
22. Morrish D, Venner P, Siy O, Barron G, Bhardwaj D, Outhet D. Mechanisms of endocrine dysfunction in patients with testicular cancer. J Natl Cancer Inst 1990;82:412-9.
23. Calkins JH, Sigel MM, Nankin HR, Lin T. Interleukin 1 inhibits Leydig cell steroidogenesis in primary culture. Endocrinology 1988; 123:1605-9.
24. Hong G, Calkins HJ, Sigel MM. Interleukin-2 is a potent inhibitor of Leydig cell steroidogenesis. Endocrinology 1990; 127:1234-9.
25. Guazzeri S, Lembo A, Ferro G, Artibani W, Merlo F, Zachetta R, et al. Sperm antibodies and infertility in patients with testicular cancer. Urology 1985;26:139-43.
26. Hendry WF, Stedronska J, Jones CR, Blackmore CA, Barrett A, Peckham MJ. Semen analysis in testicular cancer and Hodgkin's disease: pre- and posttreatment findings and implications for cryopreservation. Br J Urol 1983;:769-72.
27. Carroll PR, Morse MJ, Whitmore WF, Sogani PC, Klotz L, Herr HW, et al. Fertility status of patients with clinical stage I testis tumors on a surveillance protocol. J Urol 1987; 138:70-2.
28. Fossa SD, Theodorsen L, Norman N, Abyholm T. Recovery of impaired pretreatment spermatogenesis in testicular cancer. Fertil Steril 1990;54:493-6.
29. Aass N, Fossa SD, Theodorsen L, Norman N. Prediction of long term gonadal toxicity after standard treatment for testicular cancer. Eur J Cancer 1991;27:1087-91.
30. Johnson DH, Hainsworth JD, Linde RB, Greco FA. Testicular function following combination chemotherapy with cisplatin, vinblastine and bleomycin. Med Pediatr Oncol 1984; 12:233-8.
31. Fossa SD, Ous S, Abyholm T, Norman N, Loeb M. Post-treatment fertility in patients with testicular cancer. II. Influence of cisplatin-based combination chemotherapy and of retroperitoneal surgery on hormone and sperm cell production. Br J Urol 1985;57:210-4.
32. Kreuser ED, Kurrle E, Hetzel WD, Heymer B, Porzsolt F, Hautmann R, et al. Reversible germ cell toxicity after aggressive chemotherapy in patients with testicular cancer: results of a prospective study. Klin Wochenschr 1989; 67:367-78.
33. Leitner SP, Bosl GJ, Bajorounas D. Gonadal dysfunction in patients treated for metastatic germ cell tumors. J Clin Oncol 1986;4:1500-5.
34. Petersen PM, Hansen SW, Giwerczman A, Roørth M, Skakkebaek NE. Dose dependent impairment of testicular function in patients treated with cisplatin-based chemotherapy for germ cell cancer. Ann Oncol 1991;5:355-8.
35. Stephenson WT, Pairier SM, Rubin L, Einhorn LH. Evaluation of reproductive capacity in germ cell tumor patients following treatment with cisplatin, etoposide, and bleomycin. J Clin Oncol 1995; 13:2278-80.
36. Schilsky RL. Infertility in patients with testicular cancer: testis, tumor, or treatment? J Natl Cancer Inst 1989; 81:1204-5.
37. Hansen PV, Hansen SW. Gonadal function in men with testicular germ cell cancer: the influence of cisplatin-based chemotherapy. Eur Urol 1993;23:153-6.
38. Aass N, Fossa SD. Late side effects in patients treated for testicular cancer. Adv Biosciences 1994;91:337-43.
39. Cullen MH, Stening SP, Parkinson MC, Fossa SD, Kaye SB, Horwich AH, et al. Short-course adjuvant chemotherapy in high-risk stage I nonseminomatous germ cell tumors of the testis: a Medical Research Council report. J Clin Oncol 1996; 14:1106-13.
40. Roth BJ, Griest A, Kubilis PS, Williams SD, Einhorn LH. Cisplatin-based combination chemotherapy for disseminated germ cell tumors: long-term follow-up. J Clin Oncol 1988; 6:1239-47.
41. Bisset D, Lunkeler L, Zwanenberg L, Paul J, Gray C, Swan IRC, et al. Long-term sequelae of treatment for testicular germ cell tumors. Br J Cancer 1990;62:655-9.
42. Senturia YD, Peckham CS. Children fathered by men treated with chemotherapy for testicular cancer. Eur J Cancer 1990;26:429-32.
43. Mulvihill JJ, Myers MH, Connelley R, Byrne J, Austin DF, Brag K, et al. Cancer in offspring of longterm survivors of childhood and adolescence cancer. Lancet 1987;II: 813.
44. Fossa SD, Aass N, Molne K. Is routine pretreatment cryopreservation of semen worthwhile in the management of patients with testicular cancer? Br J Urol 1989;64:524-9.
45. Kreuser ED, Klingmůller D, Thiel E. The role of LhRH-analogues in protecting gonadal functions during chemotherapy and radiation. Eur Urol 1993:23:157-64.