IL-5 expressed by CD4+ lymphocytes from Echinococcus multilocularis- infected patients

Clinical and Experimental Immunology

Volumn 109, Issue 1, 1997, Pages 90-97

  Jenne, L ^a   Kilwinski, J ^a   Scheffold, W ^a   Kern, P ^a,b  

^a UNIVERSITY HOSPITAL ULM   (Germany)

^b UNIVERSITY OF ULM   (Germany)

Author keywords

Human alveolar echinococcosis; IL 5; T cell response; Th2 cytokines

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; COMPLEMENTARY DNA; CYTOKINE; IMMUNOGLOBULIN E ANTIBODY; INTERLEUKIN 5; MESSENGER RNA;

ADULT; AGED; ANTIGEN SPECIFICITY; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ECHINOCOCCOSIS; ECHINOCOCCUS MULTILOCULARIS; FEMALE; FLUORESCENCE ACTIVATED CELL SORTER; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOGLOBULIN PRODUCING CELL; MALE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION;

EID: 0030740631     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.1997.4031299.x     Document Type: Article

References (44)

1. Ammann R, Tschudi K, von Ziegler M, Meister F, Cotting J, Eckert J, Witassek, Freiburghaus A. The long-term course of 60 patients with alveolar echinococcosis in continuous therapy with mebendazole (1976-85). Klin Wochenschr 1988; 66:1060-73.
2. Gottstein B, Eckert J, Woodtli W. Determination of parasite specific immunoglobulins using the ELISA in patients with echinococcosis treated with mebendazole. Z Parasitenkd 1984; 70:385-9.
3. Guisantes JA, Vincente Garcia F, Abril MJ, Eraso E, Martinez J. Total and specific IgE levels in human hydatid disease determined by enzyme immunoassay: serological follow-up after surgery. J Investig Allergol Clin Immunol 1994; 4:301-4.
4. Liance M, Bresson Hadni S, Meyer JP, Houin R, Vuitton DA. Cellular immunity in experimental Echinococcus multilocularis infection. I. Sequential and comparative study of specific in vivo delayed-type hypersensitivity against E. multilocularis antigens in resistant and sensitive mice. Clin Exp Immunol 1990; 82:373-7.
5. Bresson Hadni S, Liance M, Meyer JP, Houin R, Bresson JL, Vuitton DA. Cellular immunity in experimental Echinococcus multilocularis infection. II. Sequential and comparative phenotypic study of the periparasitic mononuclear cells in resistant and sensitive mice. Clin Exp Immunol 1990; 82:378-83.
6. Street NE, Mosmann TR. Functional diversity of T lymphocytes due to secretion of different cytokine patterns. FASEB J 1991; 5:171-7.
7. Finkelman FD, Pearce EJ, Urban JF Jr, Sher A. Regulation and biological function of helminth-induced cytokine responses. Immunol Today 1991; 12:A62-66.
8. Urban JF Jr, Maliszewski CR, Madden KB, Katona IM, Finkelman FD. IL-4 treatment can cure established gastrointestinal nematode infections in immunocompetent and immunodeficient mice. J Immunol 1995; 154:4675-84.
9. Gottstein B, Wunderlin E, Tanner I. Echinococcus multilocularis: parasite-specific humoral and cellular immune response subsets in mouse strains susceptible (AKR, C57B1/6J) or 'resistant' (C57B1/10) to secondary alveolar echinococcosis. Clin Exp Immunol 1994; 96:245-52.
10. Sturm D, Menzel J, Gottstein B, Kern P. Interleukin-5 is the predominant cytokine produced by peripheral blood mononuclear cells in alveolar echinococcosis. Infect Immun 1995; 63:1688-97.
11. Fauser S, Kern P. T-lymphocyte cytokine mRNA expression in cystic echinococcosis. Acta Tropica 1997; 64:35-51.
12. Rigano R, Profumo E, Ioppolo S, Notargiacomo S, Ortona E, Teggi A. Immunological markers indicating the effectiveness of pharmacological treatment in human hydatid disease. Clin Exp Immunol 1995; 102:281-5.
13. Böyum A. Isolation of mononuclear cells and granulocytes from human blood. Scand J Clin Lab Invest 1968; 97 (Suppl.):77.
14. Chomzynsky P, Sacci N. Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chlorophorm-extraction. Anal Biochem 1987; 162:156-9.
15. Sorg R, Enczmann J, Sorg U, Heermeier K, Schneider EM, Wernet P. Rapid and sensitive mRNA phenotyping for interleukins (IL-1 to IL-6) and colony-stimulating factors (G-CSF, M-CSF, and GM-CSF) by reverse transcription and subsequent polymerase chain reaction. Exp Hematol 1991; 19:882-7.
16. Rausch RL, Wilson JF, Schantz PM, McMahon BJ. Spontaneous death of Echinococcus multilocularis: cases diagnosed serologically (by Em2 ELISA) and clinical significance. Am J Trop Med Hyg 1987; 36:576-85.
17. Bresson Hadni S, Laplante JJ, Lenys D et al. Seroepidemiologic screening of Echinococcus multilocularis infection in a European area endemic for alveolar echinococcosis. Am J Trop Med Hyg 1994; 51:837-46.
18. Lingelbach K, Hinz E. Echinococcus multilocularis: identification of proteins inducing antibody formation in metacestode infection. J Helminthol 1984; 58:1-6.
19. Gottstein B, Eckert J, Michael SA, Thompson RC. Echinococcus granulosus antigens: immunoelectrophoretic and Western blot analysis of hydatid cyst fluids. Parasitol Res 1987; 73:186-9.
20. Thompson RC. Echinococcus and Giardia: variation on a theme. Int J Parasitol 1991; 21:291-7.
21. Shcherbakov AM. Human echinococcosis: the role of histocompatibility antigens in realizing infestations and the characteristics of their course. Med Parazitol Mosk 1993; 5:13-18.
22. Dixon JB, Jenkins P. Immunology of mammalian metacestode infections. I. Antigens, protective immunity and immunopathology. Helminthological Abstracts 1995; 64:533-42.
23. Mosmann TR, Sad S. The expanding universe of T-cell subsets: Th1, Th2 and more. Immunol Today 1996; 17:138-46.
24. Yamamura M, Uyemura K, Deans RJ, Weinberg K, Rea TH, Bloom BR, Modlin RL. Defining protective responses to pathogens: cytokine profiles in leprosy lesions. Science 1991; 254 (5029):277-9.
25. + T cells in human disease: lymphokine patterns in leprosy. Chem Immunol 1992; 54:44-59.
26. Pond L, Wassom DL, Hayes CE. Influence of resistant and susceptible genotype, IL-1, and lymphoid organ on Trichinella spiralis-induced cytokine secretion. J Immunol 1992; 149:957-65.
27. Urban JF Jr, Madden KB, Svetic A, Cheever A, Trotta PP, Gause WC, Katona IM, Finkelman FD. The importance of Th2 cytokines in protective immunity to nematodes. Immunol Rev 1992; 127:205-20.
28. + T helper cell phenotype development in a T cell receptor-alpha beta-transgenic model. J Exp Med 1995; 182:1579-84.
29. + T cells. Ann Rev Immunol 1994; 12:635-73.
30. + cells. Eur J Immunol 1995; 25:587-95.
31. Rakha NK, Dixon JB, Carter SD, Craig PS, Jenkins P, Folkard S. Echinococcus multilocularis antigens modify accessory cell function of macrophages. Immunology 1991; 74:652-6.
32. + cytotoxic T-cell and Th1 cytokine responses as well as delayed virus clearance. Proc Natl Acad Sci USA 1993; 90:948-52.
33. Martinez OM, Gibbons RS, Garovoy MR, Aronson FR. IL-4 inhibits IL-2 receptor expression and IL-2-dependent proliferation of human T cells. J Immunol 1990; 144:2211-5.
34. Ho JL, He SH, Rios MJ, Wick EA. Interleukin-4 inhibits human macrophage activation by tumor necrosis factor, granulocyte-monocyte colony-stimulating factor, and interleukin-3 for antileishmanial activity and oxidative burst capacity. J Infect Dis 1992; 165:344-51.
35. Hart PH, Cooper RL, Finlay Jones JJ. IL-4 suppresses IL-1 beta, TNF-alpha and PGE2 production by human peritoneal macrophages. Immunology 1991; 72:344-9.
36. de Waal Malefyt R, Haanen J, Spits H et al. Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via down-regulation of class II major histocompatibility complex expression. J Exp Med 1991; 174:915-24.
37. Wen H, Bresson Hadni S, Vuitton DA, Lenys D, Yang BM, Ding ZX, Craig PS. Analysis of immunoglobulin G subclass in the serum antibody responses of alveolar echinococcosis patients after surgical treatment and chemotherapy as an aid to assessing the outcome. Trans R Soc Trop Med Hyg 1995; 89:692-7.
38. Mahanty S, Nutman TB. The biology of interleukin-5 and its receptor. Cancer Invest 1993; 11:624-34.
39. + T cells produce IFN-gamma and IL-5. J Immunol 1991; 147:3736-44.
40. Cardell S, Sander B, Moller G. Helper interleukins are produced by both CD4 and CD8 splenic T cells after mitogen stimulation. Eur J Immunol 1991; 21:2495-500.
41. + T cell subset with an unrestricted cytokine profile. J Immunol 1989; 143:518-25.
42. Street NE, Schumacher JH, Fong TA, Bass H, Fiorentino DF, Leverah JA, Mosmann TR. Heterogeneity of mouse helper T cells. Evidence from bulk cultures and limiting dilution cloning for precursors of Th1 and Th2 cells. J Immunol 1990; 144:1629-39.
43. Mond JJ, Vos Q, Lees A, Snapper CM. T cell independent antigens. Curr Opin Immunol 1995; 7:349-54.
44. Pearce EJ, Reiner SL. Induction of Th2 responses in infectious diseases. Curr Opin Immunol 1995; 7:497-504.