Decreased sensitivity of carcinoembryonic antigen cDNA-transfected cells to adriamycin

International Journal of Cancer

Volumn 72, Issue 2, 1997, Pages 377-382

  Kawaharata, Hitoshi ^a   Hinoda, Yuji ^a   Itoh, Fumio ^a   Endo, Takao ^a   Oikawa, Shinzo ^b   Nakazato, Hiroshi ^b   Imai, Kohzoh ^a  

^a SAPPORO MEDICAL UNIVERSITY   (Japan)

^b SUNTORY LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1 DEOXYMANNONOJIRIMYCIN; CARCINOEMBRYONIC ANTIGEN; COMPLEMENTARY DNA; DOXORUBICIN; GLYCOPROTEIN P; VERAPAMIL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; BLADDER CARCINOMA; CELL STRAIN 3T3; CELL TRANSFORMATION; CONTROLLED STUDY; DNA TRANSFECTION; DRUG ACCUMULATION; DRUG SENSITIVITY; FEMALE; FIBROBLAST; GLYCOSYLATION; INTRAPERITONEAL DRUG ADMINISTRATION; MOUSE; NONHUMAN; ONCOGENE H RAS; PRIORITY JOURNAL; SCID MOUSE;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; CARCINOEMBRYONIC ANTIGEN; CELL LINE; DNA, COMPLEMENTARY; DOXORUBICIN; DRUG RESISTANCE, MICROBIAL; FIBROBLASTS; MICE; TRANSFECTION;

EID: 0030740284     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19970717)72:2<377::AID-IJC29>3.0.CO;2-B     Document Type: Article

References (20)

1. ARSENAULT, A.L., VICTOR, L. and NORBERT, K., Altered plasma membrane ultrastructure in multidrug-resistant cells. Biochim. biophys. Acta, 938, 315-321 (1988).
2. BENCHIMOL, S., FUKS, A., JOTHY, S., BEAUCHEMIN, N., SHIROTA, K. and STANNERS, C.P., Carcinoembryonic antigen, a human tumor marker, functions as an intercellular adhesion molecule. Cell, 57, 327-334 (1989).
3. BRADLEY, G., JURANKA, P.F. and LING, V., Mechanism of multidrug resistance. Biochim. biophys. Acta, 948, 87-128 (1988).
4. BREUNINGER, L.M., PAUL, A., GAUGHAN, K., MIKI, T., CHAN, A., AARONSON, S.A. and KRUH, G.D., Expression of multidrug resistance-associated protein in NIH/3T3 cells confers multidrug resistance associated with increased drug efflux and altered intracellular drug distribution. Cancer Res., 55, 5342-5347 (1995).
5. GARCIA, M., SEIGNER, C., BASTID, C., CHOUX, R., PAYAN, M.J. and REGGIO, H., Carcinoembryonic antigen has a different molecular weight in normal colon and in cancer cells due to N-glycosylation differences. Cancer Res., 51, 5679-5686 (1991).
6. HERZOG, C.E., TSOKOS, M., BATES, S.E. and FOJO, A.T., Increased mdr-1/P-clycoprotein expression after treatment of human colon carcinoma cells with P-glycoprotein antagonists. J. biol. Chein., 268, 2946-2952 (1993).
7. HO, S.B., YAN, P-S., DAHIYA, R., NEUSCHWANDER-TETRI, B.A., BASBAUM, C. and KIM, Y.S., Stable differentiation of a human colon adenocarcinoma cell line by sodium butyrate is associated with multidrug resistance. J. Cell. Physiol., 160, 213-226 (1994).
8. ISONISHI, S., HOM, D.K., THIEBAUT, F.B., MANN, S.C., ANDREWS, P.A., BASU, A., LAZO, J.S., EASTMAN, A. and HOWELL, S.B., Expression of the c-Ha-ras oncogene in mouse NIH 3T3 cells induces resistance to cisplatin. Cancer Res., 51, 5903-5909 (1991).
9. LIOTTA, L.A., RAO, C.N. and WEWER, U.M., Biochemical interactions of tumor cells with the basement membrane. Ann. Rev. Biochem., 55, 1037-1057 (1986).
10. MAKIGUCHI, Y., HINODA, Y. and IMAI, K., Effect of MUC1 mucin, an anti-adhesion molecule, on tumor cell growth. Jpn. J. Cancer Res., 87, 505-511 (1996).
11. OIKAWA, S., NAKAZATAO, H. and KOZAKI, G., Primary structure of human carcinoembryonic antigen (CEA) deduced from cDNA sequence. Biochem. biophys. Res. Comm., 142, 511-518 (1987).
12. PAXTON, R.J., MOOSER, G., PANDE, H., LEE, T.D. and SHIVELY, J.E., Sequence analysis of carcinoembryonic antigen: identification of glycosylation sites and homology with the immunoglobulin supergene family. Proc. nat. Acad. Sci. (Wash.), 84, 920-924 (1987).
13. SCHUURHUIS, G.J., VAN HEIJINGEN, T.H.M., CERVANTES, A., PINEDO, H.M., DE LANGE, J.H.M., KEIZER, H.G., BROXTEMAN, H.J., BAAK, J.P.A. and LANKELMA, J., Changes in subcellular doxorubicin distribution and cellular accumulation alone can largely account for doxorubicin resistance in SW-1573 lung cancer and MCF-7 breast cancer multidrug resistant tumor cells. Brit. J. Cancer, 68, 898-908 (1993).
14. SCULIER, J.P., FELD, R., EVANS, W.K., SHEPHERD, F.A., DEBOER, G., MALKIN, D.G. and MALKIN, A., Carcinoembryonic antigen: a useful prognostic marker in small-cell lung cancer. J. clin. Oncol., 3, 1349-1354 (1985).
15. SEGAWA, Y., OHNISHI, T., HIRAKI, S., UEOKA, H., KIURA, K., KAMEI, H., TABATA, M., SHIBAYAMA, T., MIYATAKE, K., GENBA, K., MATSUMURA, T. and KIMURA, I., Immunohistochemical detection of P-glycoprotein and carcinoembryonic antigen in small cell lung cancer: with reference to predictable response to chemotherapy. Acta med. Okayama, 47, 181-189 (1993).
16. SEHESTED, M., SKOVSGAARD, T., VAN DEURS, B. and WINTHER-NIELSEN, H., Increased plasma membrane traffic in daunorubicin resistant P388 leukemic cells. Effect of daunorubicin and verapamil. Brit. J. Cancer, 56, 747-751 (1987).
17. SIMON, S.M. and SCHINDLER, M., Cell biological mechanism of multidrug resistance in tumors. Proc. nat. Acad. Sci. (Wash.), 91, 3497-3504 (1994).
18. SKLAR, M.D., Increased resistance to cis-diamminedichloroplatinum (II) in NIH 3T3 cells transformed by ras oncogenes. Cancer Res., 48, 793-797 (1988).
19. TAPIERO, H., FOURCADE, A., VAIGOT, P., and FARHI, J.J., Comparative uptake of adriamycin and daunorubicin in sensitive and resistant friend leukemia cells measured by flow cytometry. Cytometry, 2, 298-302 (1982).
20. TRITTON, T.R. and YEE, G., The anticancer agent adriamycin can be actively cytotoxic without entering cells. Science. 217, 248-250 (1982).