Parathyroid hormone gene expression in Hyp mice fed a low-phosphate diet

Nephrology Dialysis Transplantation

Volumn 12, Issue 8, 1997, Pages 1581-1585

  Marks, K H ^a   Kilav, R ^a   Berman, E ^a   Naveh Many, T ^a   Silver, J ^a  

^a HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

Author keywords

Hyp; Phosphate; PTH; PTH mRNA; Vitamin D

Indexed keywords

MESSENGER RNA; PARATHYROID HORMONE; PHOSPHATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM BLOOD LEVEL; CONTROLLED STUDY; GENE EXPRESSION; GENOTYPE; HYPOPHOSPHATEMIA; INTRACELLULAR FLUID; KIDNEY TUBULE ABSORPTION; KIDNEY TUBULE DISORDER; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHOSPHATE BLOOD LEVEL; PHOSPHATE INTAKE; PRIORITY JOURNAL; VITAMIN D RESISTANT RICKETS;

ANIMALS; BODY WEIGHT; CALCIUM; ENERGY METABOLISM; FEMALE; GENE EXPRESSION; HYPOPHOSPHATEMIA; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MICE; MICE, MUTANT STRAINS; PARATHYROID HORMONE; PHOSPHATES; PHOSPHORUS, DIETARY; RATS; RNA, MESSENGER; TIME FACTORS;

EID: 0030739577     PISSN: 09310509     EISSN: None     Source Type: Journal    
DOI: 10.1093/ndt/12.8.1581     Document Type: Article

References (21)

1. Econs MJ, Drezner MK. Bone disease resulting from inherited disorders of renal tubule transport and vitamin D metabolism. In: Coe FL, Favus MJ (ed.). Disorders of Bone and Mineral Metabolism. Raven Press, New York, 1991; 935-950
2. Tanaka Y, DeLuca HF. The control of vitamin D by inorganic phosphorus. Arch Biochem Biophys 1973; 154: 566-570
3. Kilav R, Silver J, Naveh-Many T. Parathyroid hormone gene expression in hypophosphatemic rats, J Clin Invest 1995; 96: 327-333
4. Naveh-Many T, Rahamimov R, Livni N, Silver J. Parathyroid cell proliferation in normal and chronic renal failure rats: the effects of calcium, phosphate and vitamin D. J Clin Invest 1995; 96: 1786-1793
5. Almaden Y, Canalejo A, Hernandez A et al. Direct effect of phosphorus on parathyroid hormone secretion from whole rat parathyroid glands in vitro. J Bone Miner Res 1996; 11: 970-976
6. Nielsen PK, Feldt-Rasmusen U, Olgaard K. A direct effect of phosphate on PTH release from bovine parathyroid tissue slices but not from dispersed parathyroid cells. Nephrol Dial Transplant 1996; 11: 1762-1768
7. Slatopolsky E, Finch J, Denda M et al. Phosphate restriction prevents parathyroid cell growth in uremic rats. High phosphate directly stimulates PTH secretion in vitro. J Clin Invest 1996; 97: 2534-2540
8. Hernandez A, Conception MT, Rodriguez M, Salido E, Torres A. High phosphorus diet increases preproPTH mRNA independent of calcium and calcitriol in normal rats. Kidney Int 1996; 50: 1872-1878
9. Chance B, Leigh JS, McLaughlin AC, Schnall M, Sinnwell T. Phosphorus-31 spectroscopy and imaging. In: Partain CL, Price RR, Patton JA, Kulkarni MV, James AE (eds.). Magnetic Resonance Spectroscopy. Saunders, Philadelphia, 1988; 1501-1520
10. Naveh-Many T, Almogi G, Livni N, Silver J. Estrogen receptors and biologic response in rat parathyroid tissue and C-cells. J Clin Invest 1992; 90: 2434-2438
11. Silver J, Naveh-Many T, Mayer H, Schmelzer HJ, Popovtzer MM. Regulation by vitamin D metabolites of parathyroid hormone gene transcription in vivo in the rat. J Clin Invest 1986; 78: 1296-1301
12. Meyer RA, Meyer MH, Morgan PL. Effects of altered diet on serum levels of 1,25-dihydroxyvitamin D and parathyroid hormone in X-linked hypophosphatemia (Hyp and Gy) mice. Bone 1996; 18: 23-28
13. Nesbitt T, Drezner MK, Lobaugh B. Abnormal parathyroid hormone stimulation of 25-hydroxyvitamin D1 alphahydroxylase activity in the hypophosphatemic mouse. Evidence for a generalized defect of vitamin D metabolism. J Clin Invest 1986; 77: 181-187
14. Tenenhouse HS, Martel J. Renal adaptation to phosphate deprivation: lessons from the X-linked Hyp mouse. Pediatr Nephrol 1993; 7: 312-318
15. Naveh-Many T, Raue F, Grauer A, Silver J. Regulation of calcitonin gene expression by hypocalcemia, hypercalcemia, and vitamin D in the rat. J Bone Miner Res 1992; 7: 1233-1237
16. Naveh-Many T, Silver J. Regulation of parathyroid hormone gene expression by hypocalcemia, hypercalcemia, and vitamin D in the rat. J Clin Invest 1990; 86: 1313-1319
17. Chobanian MC, Anderson ME, Brazy PC. An NMR study of cellular phosphates and membrane transport in renal proximal tubules. Am J Physiol 1995; 268: F375-F384
18. Knudtzon J, Halse J, Monn E et al. Autonomous hyperparathyroidism in X-linked hypophosphataemia. Clin Endocrinol 1995; 42: 199-203
19. Rivkees SA, El-Hajj-Fuleihan G, Brown EM, Crawford JD. Tertiary hyperparathyroidism during high phosphate therapy of familial hypophosphatemic rickets. J Clin Endocrinol Metab 1992; 75: 1514-1518
20. The Hyp consortium, A gene (PEX) with homologies to endopeptidases is mutated in patients with X-linked hypophosphataemic rickets. Nature Genetics 1995; 11: 130-136
21. Beck L, Soumounou Y, Martel J et al. Pex/PEX tissue distribution and evidence for a deletion in the 3' region of the Pex gene in X-linked hypophosphatemic mice. J Clin Invest 1997; 99: 1200-1209