Effect of magnesium on vascular tone and reactivity in pressurized mesenteric resistance arteries from spontaneously hypertensive rats

Canadian Journal of Physiology and Pharmacology

Volumn 75, Issue 4, 1997, Pages 293-300

  Laurant, Pascal ^a   Touyz, Rhian M ^b   Schiffrin, Ernesto L ^b  

^a UNIVERSITÉ DE FRANCHE COMTÉ   (France)

^b CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

Author keywords

Blood vessels; Hypertension; Norepinephrine; Spontaneously hypertensive rat; Vasopressin

Indexed keywords

MAGNESIUM;

ANIMAL MODEL; ARTERY RESISTANCE; ARTICLE; BLOOD VESSEL REACTIVITY; BLOOD VESSEL TONE; DRUG EFFECT; HYPERTENSION; MESENTERIC ARTERY; NONHUMAN; PRIORITY JOURNAL; RAT; SPONTANEOUSLY HYPERTENSIVE RAT;

EID: 0030739570     PISSN: 00084212     EISSN: None     Source Type: Journal    
DOI: 10.1139/y97-044     Document Type: Article

References (33)

1. Altura, B.M. 1974. Magnesium - neurohypophyseal hormone interactions in contraction of vascular smooth muscle. Am. J. Physiol. 228: 1615-1620.
2. Altura, B.M., and Altura, B.T. 1978. Magnesium and vascular tone and reactivity. Blood Vessels, 15: 5-16.
3. Altura, B.M., and Altura, B.T. 1981. Magnesium ions and contraction of vascular smooth muscle: relationship to some vascular diseases. Fed. Proc. 40: 2672-2679.
4. Altura, B.M., and Altura, B.T. 1983. Influence of magnesium on vascular smooth muscle and serum biochemical parameters from diabetic and hypertensive rats. Magnesium, 32: 253-266.
5. 2+ versus organic calcium channel blockers on myogenic tone and agonist-induced responsiveness of blood vessels. Can. J. Physiol. Pharmacol. 65: 729-745.
6. Altura, B.M., Altura, B.T., Gebrewold, A., Ising, H., and Gunther, T. 1992. Noise-induced hypertension and magnesium in rats: relationship to microcirculation and calcium. J. Appl. Physiol. 72: 194-202.
7. Baumbach, G.L., and Heistad, D.D. 1989. Remodeling of cerebral arterioles in chronic hypertension. Hypertension (Dallas), 13: 968-972.
8. Berthelot, A., and Esposito, J. 1983. Effects of dietary magnesium on the development of hypertension in spontaneously hypertensive rat. J. Am. Coll. Nutr. 4: 343-353.
9. Evans, G.H., Weaver, C.M., and Harrington, D.D. 1989. Dietary magnesium does not affect blood pressure in spontaneously hypertensive rats. Clin. Exp. Hypertens. Part A, Theory Pract. 11: 619-632.
10. Falloon, B.J., and Heagerty, A.M. 1994. In vitro perfusion studies of human resistance artery function in essential hypertension. Hypertension (Dallas), 24: 16-23.
11. Falloon, B.J., Bund, S.J., Tulip, J.R., and Heagerty, A.M. 1993. In vitro perfusion studies of resistance artery function in genetic hypertension. Hypertension (Dallas), 22: 486-495.
12. Falloon, B.J., Stephens, N., Tulip, J.R., and Heagerty, A.M. 1995. Comparison of small artery sensitivity and morphology in pressurized and wire-mounted preparations. Am. J. Physiol. 268: H670-H678.
13. Folkow, B. 1982. Physiological aspects of primary hypertension. Physiol. Rev. 62: 347-504.
14. 2+ in young patients with borderline hypertension. Circulation, 2: 384-395.
15. Halpern, W., and Kelley, M. 1991. In vitro methodology for resistance arteries. Blood Vessels, 8: 245-251.
16. Heagerty, A.M., Aalkjaer, C., Bund, S.J., Korsgaard, N., and Mulvany, M.J. 1993. Small artery structure in hypertension. Dual processes of remodeling and growth. Hypertension (Dallas), 21: 391-397.
17. Jelicks, L. A., and Gupta, R.K. 1990. NMR measurement of cytosolic free calcium, free magnesium and intracellular sodium in the aorta of the normal and spontaneously hypertensive rat. J. Biol. Chem. 265: 1394-1400.
18. Ku, D.D., and Ann, H.S. 1987. Magnesium deficiency produces endothelium-dependent vasorelaxation in canine coronary arteries. J. Pharmacol. Exp. Ther. 241: 961-966.
19. Larivière, R., St-Louis, J., and Schiffrin, E.L. 1989. Vasopressin receptors and inositol triphosphate production in blood vessel of spontaneously hypertensive rats. Can. J. Physiol. Pharmacol. 67: 232-239.
20. Laurant, P.M., Touyz, R.M., and Schiffrin, E.L. 1997. Effect of pressurization on mechanical properties of perfused mesenteric small arteries from spontaneously hypertensive rats. J. Vasc. Res. In press.
21. 2+- and time-dependent mechanism. J. Biol. Chem. 266: 4764-4771.
22. Mulvany, M.J., and Aalkjaer, C. 1990. Structure and function of small arteries. Physiol. Rev. 70: 921-961.
23. Mulvany, M.J., Aalkjaer, C., and Christensen, J. 1980. Changes in noradrenaline sensitivity and morphology of arterial resistance vessels during development of high blood pressure in spontaneously hypertensive rats. Hypertension (Dallas), 2: 664-671.
24. Ng, L.L., Davies, J.L., and Ameen, M. 1992. Intracellular free-magnesium levels in vascular smooth muscle and striated muscle cells of the spontaneously hypertensive rats. Metabolism, 41: 772-777.
25. Nishio, A., Gebrewold, A., Altura, B.T., and Altura, B.T. 1988. Comparative effects of magnesium salts on reactivity of arterioles and venules to constrictor agents. An in situ study on microcirculation. J. Pharmacol. Exp. Ther. 246: 859-965.
26. Resnick, L.M., Gupta, R.K., and Laragh, J.H. 1984. Intracellular free magnesium in erythrocytes of essential hypertension: relation to blood pressure and serum divalent cations. Proc. Natl. Acad. Sci. U.S.A. 81: 6511-6517.
27. Schiffrin, E.L. 1995. Remodeling of resistance arteries in human hypertension: effects of cilazapril, an angiotensin-I-converting enzyme inhibitor. Cardiology, 86(Suppl. 1): 16-22.
28. Sharma, R.V., and Bhalla, R.C. 1989. Calcium and abnormal reactivity of vascular smooth muscle in hypertension. Cell Calcium, 9: 267-274.
29. Touyz, R.M., and Schiffrin, E.L. 1993. Signal transduction in hypertension: part II. Curr. Opin. Nephrol. Hypertens. 2: 17-26.
30. Touyz, R.M., Deng, L.Y., and Schiffrin, E.L. 1996. Differential effects of vasopressin and endothelin-1 on vascular contractile and calcium responses in small arteries from SHR. J. Hypertens. 14: 983-991.
31. Turlapaty, P.D.M.V., and Altura, B.M. 1978. Extracellular magnesium ions control calcium exchange and content of vascular smooth muscle. Eur. J. Pharmacol. 52: 421-423.
32. Zemel, P.C., Zemel, M.B., Urberg, M., Douglas, F.L., Geiser, R., and Sowers, J.R. 1990. Metabolic and hemodynamic effects of magnesium supplementation in patients with essential hypertension. Am. J. Clin. Nutr. 51: 665-669.
33. Zhang, A., Cheng, T.P.O., and Altura, B.M. 1992. Magnesium regulates intracellular free ionized calcium concentration and cell geometry in vascular smooth muscle cells. Biochim. Biophys. Acta, 1134: 25-29.