메뉴 건너뛰기




Volumn 80, Issue 4, 1997, Pages 1101-1111

Shortened-duration GABA(A) receptor-mediated synaptic potentials underlie enhanced CA1 excitability in a chronic model of temporal lobe epilepsy

Author keywords

Epilepsy; GABA(A); Hippocampus; Inhibition; IPSP; Zolpidem

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID B RECEPTOR; BENZODIAZEPINE RECEPTOR; BENZODIAZEPINE RECEPTOR STIMULATING AGENT; GLUTAMIC ACID; IONOTROPIC RECEPTOR; ZOLPIDEM;

EID: 0030739014     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(97)00148-6     Document Type: Article
Times cited : (25)

References (59)
  • 1
    • 0020001035 scopus 로고
    • Feedforward dendritic inhibition in rat hippocampal pyramidal cells studied in vitro
    • Alger B. E. and Nicoll R. A. (1982) Feedforward dendritic inhibition in rat hippocampal pyramidal cells studied in vitro. J. Physiol. 328, 105-123.
    • (1982) J. Physiol. , vol.328 , pp. 105-123
    • Alger, B.E.1    Nicoll, R.A.2
  • 2
    • 0021872980 scopus 로고
    • Pharmacological profile of the imidazopyridine zolpidem at benzodiazepine receptors and electrocorticogram in rats
    • Arbilla S., Depoortere H., George P. and Langer S. Z. (1985) Pharmacological profile of the imidazopyridine zolpidem at benzodiazepine receptors and electrocorticogram in rats. Naunyn-Schmiedeberg's Arch. Pharmac. 330, 248-251.
    • (1985) Naunyn-Schmiedeberg's Arch. Pharmac. , vol.330 , pp. 248-251
    • Arbilla, S.1    Depoortere, H.2    George, P.3    Langer, S.Z.4
  • 3
    • 0024560608 scopus 로고
    • Electrophysiological properties and synaptic responses in the deep layers of the human epileptogenic neocortex in vitro
    • Avoli M. and Olivier A. (1989) Electrophysiological properties and synaptic responses in the deep layers of the human epileptogenic neocortex in vitro. J. Neurophysiol. 61, 589-606.
    • (1989) J. Neurophysiol. , vol.61 , pp. 589-606
    • Avoli, M.1    Olivier, A.2
  • 4
    • 0024322622 scopus 로고
    • Glutamate decarboxylase-immunoreactive neurons are preserved in human epileptic hippocampus
    • Babb T. L., Pretorius J. K., Kupfer W. R. and Crandall P. H. (1989) Glutamate decarboxylase-immunoreactive neurons are preserved in human epileptic hippocampus. J. Neurosci. 9, 2562-2574.
    • (1989) J. Neurosci. , vol.9 , pp. 2562-2574
    • Babb, T.L.1    Pretorius, J.K.2    Kupfer, W.R.3    Crandall, P.H.4
  • 5
    • 0028149673 scopus 로고
    • The evolution of a rat model of chronic spontaneous limbic seizures
    • Bertram E. H. and Cornett J. F. (1994) The evolution of a rat model of chronic spontaneous limbic seizures. Brain Res. 661, 157-162.
    • (1994) Brain Res. , vol.661 , pp. 157-162
    • Bertram, E.H.1    Cornett, J.F.2
  • 6
    • 0030593034 scopus 로고    scopus 로고
    • Zinc-induced collapse of augmented inhibition by GABA in a temporal lobe epilepsy model
    • Buhl E. H., Otis T. S. and Mody I. (1996) Zinc-induced collapse of augmented inhibition by GABA in a temporal lobe epilepsy model. Science 271, 369-372.
    • (1996) Science , vol.271 , pp. 369-372
    • Buhl, E.H.1    Otis, T.S.2    Mody, I.3
  • 7
    • 0026460094 scopus 로고
    • Benzodiazepine receptor binding of nonbenzodiazepines in vivo: Alpidem, zolpidem, and zopiclone
    • Byrnes J. J., Greenblatt D. J. and Miller L. G. (1992) Benzodiazepine receptor binding of nonbenzodiazepines in vivo: alpidem, zolpidem, and zopiclone. Brain Res. Bull. 29, 905-908.
    • (1992) Brain Res. Bull. , vol.29 , pp. 905-908
    • Byrnes, J.J.1    Greenblatt, D.J.2    Miller, L.G.3
  • 8
    • 0024546897 scopus 로고
    • Horizontal spread of synchronized activity in neocortex and its control by GABA-mediated inhibition
    • Chagnac-Amitai Y. and Connors B. W. (1989) Horizontal spread of synchronized activity in neocortex and its control by GABA-mediated inhibition. J. Neurophysiol. 61, 747-758.
    • (1989) J. Neurophysiol. , vol.61 , pp. 747-758
    • Chagnac-Amitai, Y.1    Connors, B.W.2
  • 10
    • 0025357856 scopus 로고
    • Paired-pulse depression of monosynaptic GABA-mediated inhibitory postsynaptic responses in rat hippocampus
    • Davies C. H., Davies S. N. and Collingridge G. L. (1990) Paired-pulse depression of monosynaptic GABA-mediated inhibitory postsynaptic responses in rat hippocampus. J. Physiol., Lond. 424, 513-531.
    • (1990) J. Physiol., Lond. , vol.424 , pp. 513-531
    • Davies, C.H.1    Davies, S.N.2    Collingridge, G.L.3
  • 11
    • 0018910562 scopus 로고
    • Reduced inhibition during epileptiform activity in the in vitro hippocampal slice
    • Dingledine R. and Gjerstad L. (1980) Reduced inhibition during epileptiform activity in the in vitro hippocampal slice. J. Physiol., Lond. 305, 297-313.
    • (1980) J. Physiol., Lond. , vol.305 , pp. 297-313
    • Dingledine, R.1    Gjerstad, L.2
  • 12
    • 0029011707 scopus 로고
    • Hippocampal GABA transporter function in temporal lobe epilepsy
    • During M. J., Ryder K. M. and Spencer D. D. (1995) Hippocampal GABA transporter function in temporal lobe epilepsy. Nature 376, 174-177.
    • (1995) Nature , vol.376 , pp. 174-177
    • During, M.J.1    Ryder, K.M.2    Spencer, D.D.3
  • 13
    • 0025087071 scopus 로고
    • Quantal analysis of inhibitory synaptic transmission in the dentate gyrus of rat hippocampal slices: A patch-clamp study
    • Edwards F. A., Konnerth A., Sakmann B. and Busch C. (1990) Quantal analysis of inhibitory synaptic transmission in the dentate gyrus of rat hippocampal slices: a patch-clamp study. J. Physiol., Lond. 430, 213-249.
    • (1990) J. Physiol., Lond. , vol.430 , pp. 213-249
    • Edwards, F.A.1    Konnerth, A.2    Sakmann, B.3    Busch, C.4
  • 14
    • 0023881331 scopus 로고
    • Inhibition in kainate-lesioned hyperexcitable hippocampi: Physiological, autoradiographic, and immunocytochemical observations
    • Franck J. E., Kunkel D. D., Baskin D. G. and Schwartzkroin P. A. (1988) Inhibition in kainate-lesioned hyperexcitable hippocampi: physiological, autoradiographic, and immunocytochemical observations. J. Neurosci. 8, 1991-2002.
    • (1988) J. Neurosci. , vol.8 , pp. 1991-2002
    • Franck, J.E.1    Kunkel, D.D.2    Baskin, D.G.3    Schwartzkroin, P.A.4
  • 15
    • 0028181830 scopus 로고
    • A receptors containing the α1 subunit to neurochemically distinct subpopulations of rat hippocampal interneurons
    • A receptors containing the α1 subunit to neurochemically distinct subpopulations of rat hippocampal interneurons. Eur. J. Neurosci. 6, 837-853.
    • (1994) Eur. J. Neurosci. , vol.6 , pp. 837-853
    • Gao, B.1    Fritschy, J.M.2
  • 17
    • 0029416984 scopus 로고
    • A receptor gating kinetics on the α-subunit isoform: Implications for structure-function relations and synaptic transmission
    • A receptor gating kinetics on the α-subunit isoform: implications for structure-function relations and synaptic transmission. J. Physiol. 489, 529-543.
    • (1995) J. Physiol. , vol.489 , pp. 529-543
    • Gingrich, K.J.1    Roberts, W.A.2    Kass, R.S.3
  • 18
    • 0021255627 scopus 로고
    • Picrotoxin-induced epileptiform activity in hippocampus: Role of endogenous versus synaptic factors
    • Hablitz J. J. (1984) Picrotoxin-induced epileptiform activity in hippocampus: role of endogenous versus synaptic factors. J. Neurophysiol. 51, 1011-1027.
    • (1984) J. Neurophysiol. , vol.51 , pp. 1011-1027
    • Hablitz, J.J.1
  • 19
    • 0025800091 scopus 로고
    • GABA neurons in seizure disorders: A review of immunocytochemical studies
    • Houser C. R. (1991) GABA neurons in seizure disorders: a review of immunocytochemical studies. Neurochem. Res. 16, 295-308.
    • (1991) Neurochem. Res. , vol.16 , pp. 295-308
    • Houser, C.R.1
  • 20
    • 0029112106 scopus 로고
    • A channel responses to brief agonist pulses
    • A channel responses to brief agonist pulses. Neuron 15, 181-191.
    • (1995) Neuron , vol.15 , pp. 181-191
    • Jones, M.V.1    Westbrook, G.L.2
  • 21
    • 0027372927 scopus 로고
    • Potassium-induced changes in excitability in the hippocampal CA1 region of immature and adult rats
    • Kreisman N. R. and Smith M. L. (1993) Potassium-induced changes in excitability in the hippocampal CA1 region of immature and adult rats. Devl Brain Res. 76, 67-73.
    • (1993) Devl Brain Res. , vol.76 , pp. 67-73
    • Kreisman, N.R.1    Smith, M.L.2
  • 22
    • 0024521215 scopus 로고
    • Self-sustaining limbic status epilepticus induced by "conlinuous" hippocampal stimulation: Electrographic and behavioral characteristics
    • Lothman E. W., Bertram E. H., Bekenstein J. W. and Perlin J. B. (1989) Self-sustaining limbic status epilepticus induced by "conlinuous" hippocampal stimulation: electrographic and behavioral characteristics. Epilepsy Res. 3, 107-119.
    • (1989) Epilepsy Res. , vol.3 , pp. 107-119
    • Lothman, E.W.1    Bertram, E.H.2    Bekenstein, J.W.3    Perlin, J.B.4
  • 23
    • 0025326575 scopus 로고
    • Recurrent spontaneous hippocampal seizures in the rat as a chronic sequela to limbic status epilepticus
    • Lothman E. W., Bertram E. H., Kapur J. and Stringer J. L. (1990) Recurrent spontaneous hippocampal seizures in the rat as a chronic sequela to limbic status epilepticus. Epilepsy Res. 6, 110-118.
    • (1990) Epilepsy Res. , vol.6 , pp. 110-118
    • Lothman, E.W.1    Bertram, E.H.2    Kapur, J.3    Stringer, J.L.4
  • 25
    • 0029095708 scopus 로고
    • Changes in excitatory neurotransmission in the CA1 region and dentate gyrus in a chronic model of temporal lobe epilepsy
    • Lothman E. W., Rempe D. A. and Mangan P. S. (1995) Changes in excitatory neurotransmission in the CA1 region and dentate gyrus in a chronic model of temporal lobe epilepsy. J. Neurophysiol. 74, 841-848.
    • (1995) J. Neurophysiol. , vol.74 , pp. 841-848
    • Lothman, E.W.1    Rempe, D.A.2    Mangan, P.S.3
  • 28
    • 0029092668 scopus 로고
    • Changes in inhibitory neurotransmission in the CA1 region and dentate gyrus in a chronic model of temporal lobe epilepsy
    • Mangan P. S., Rempe D. A. and Lothman E. W. (1995) Changes in inhibitory neurotransmission in the CA1 region and dentate gyrus in a chronic model of temporal lobe epilepsy. J. Neurophysiol. 74, 829-840.
    • (1995) J. Neurophysiol. , vol.74 , pp. 829-840
    • Mangan, P.S.1    Rempe, D.A.2    Lothman, E.W.3
  • 29
    • 0029816967 scopus 로고    scopus 로고
    • B receptor mediated processes in region CA1 in a chronic model of temporal lobe epilepsy
    • B receptor mediated processes in region CA1 in a chronic model of temporal lobe epilepsy. J. Neurophysiol. 76, 1282-1296.
    • (1996) J. Neurophysiol. , vol.76 , pp. 1282-1296
    • Mangan, P.S.1    Lothman, E.W.2
  • 30
    • 0024351780 scopus 로고
    • Epileptiform discharges evoked in hippocampal brain slices from epileptic patients
    • Masukawa L. M., Higashima M., Kim J. H. and Spencer D. D. (1989) Epileptiform discharges evoked in hippocampal brain slices from epileptic patients. Brain Res. 493, 168-174.
    • (1989) Brain Res. , vol.493 , pp. 168-174
    • Masukawa, L.M.1    Higashima, M.2    Kim, J.H.3    Spencer, D.D.4
  • 32
    • 0023162358 scopus 로고
    • Inhibitory control of local excitatory circuits in the guinea-pig hippocampus
    • Miles R. and Wong R. K. S. (1987) Inhibitory control of local excitatory circuits in the guinea-pig hippocampus. J. Physiol., Lond. 388, 611-629.
    • (1987) J. Physiol., Lond. , vol.388 , pp. 611-629
    • Miles, R.1    Wong, R.K.S.2
  • 34
    • 0018287652 scopus 로고
    • Pharmacological characterization of different types of GABA and glutamate receptors in vertebrates and invertebrates
    • Nistri A. and Constanti A. (1979) Pharmacological characterization of different types of GABA and glutamate receptors in vertebrates and invertebrates. Prog. Neurbiol. 13, 117-235.
    • (1979) Prog. Neurbiol. , vol.13 , pp. 117-235
    • Nistri, A.1    Constanti, A.2
  • 35
    • 0026697352 scopus 로고
    • A receptor-mediated spontaneous inhibitory postsynaptic currents in hippocampal neurons
    • A receptor-mediated spontaneous inhibitory postsynaptic currents in hippocampal neurons. Neuroscience 49, 13-32.
    • (1992) Neuroscience , vol.49 , pp. 13-32
    • Otis, T.S.1    Mody, I.2
  • 36
    • 0028136698 scopus 로고
    • Lasting potentialtion of inhibition is associated with an increased number of γ-aminobutyric acid type A receptors activated during miniature inhibitory postsynaptic currents
    • Otis T. S., De Koninck Y. and Mody I. (1994) Lasting potentialtion of inhibition is associated with an increased number of γ-aminobutyric acid type A receptors activated during miniature inhibitory postsynaptic currents. Proc. natn. Acad. Sci. U.S.A. 91, 7698-7702.
    • (1994) Proc. Natn. Acad. Sci. U.S.A. , vol.91 , pp. 7698-7702
    • Otis, T.S.1    De Koninck, Y.2    Mody, I.3
  • 37
    • 0028243304 scopus 로고
    • Potassium-dependent prolonged field bursts in the dentate gyrus: Effects of extracellular calcium and amino acid antagonists
    • Patrylo P. R., Schweitzer J. S. and Dudek F. E. (1994) Potassium-dependent prolonged field bursts in the dentate gyrus: effects of extracellular calcium and amino acid antagonists. Neuroscience 61, 13-19.
    • (1994) Neuroscience , vol.61 , pp. 13-19
    • Patrylo, P.R.1    Schweitzer, J.S.2    Dudek, F.E.3
  • 38
    • 0027399657 scopus 로고
    • A responses in rat hippocampus
    • A responses in rat hippocampus. Neuron 10, 189-200.
    • (1993) Neuron , vol.10 , pp. 189-200
    • Pearce, R.A.1
  • 39
    • 0029995077 scopus 로고    scopus 로고
    • Axonal sprouting of CA1 pyramidal cells in hyperexcitable hippocampal slices of kainate-treated rats
    • Perez Y., Morin F., Beaulieu C. and Lacaille J.-C. (1996) Axonal sprouting of CA1 pyramidal cells in hyperexcitable hippocampal slices of kainate-treated rats. Eur. J. Neurosci. 8, 736-748.
    • (1996) Eur. J. Neurosci. , vol.8 , pp. 736-748
    • Perez, Y.1    Morin, F.2    Beaulieu, C.3    Lacaille, J.-C.4
  • 40
    • 0029117218 scopus 로고
    • Regional heterogeneity of pathophysiological alterations in CA1 and dentate gyrus in a chronic model of temporal lobe epilepsy
    • Rempe D. A., Mangan P. S. and Lothman E. W. (1995) Regional heterogeneity of pathophysiological alterations in CA1 and dentate gyrus in a chronic model of temporal lobe epilepsy. J. Neurophysiol. 74, 816-828.
    • (1995) J. Neurophysiol. , vol.74 , pp. 816-828
    • Rempe, D.A.1    Mangan, P.S.2    Lothman, E.W.3
  • 41
    • 0342891979 scopus 로고    scopus 로고
    • Area CA1 interneurons remain functionally connected to excitatory synaptic input in chronically epileptic animals
    • in press
    • Rempe D. A., Bertram E. H., Williamson J. M. and Lothman E. W. (1997) Area CA1 interneurons remain functionally connected to excitatory synaptic input in chronically epileptic animals. J. Neurophysiol., (in press).
    • (1997) J. Neurophysiol.
    • Rempe, D.A.1    Bertram, E.H.2    Williamson, J.M.3    Lothman, E.W.4
  • 42
    • 0027992775 scopus 로고
    • Factors contributing to the decay of the stimulus-evoked IPSC in rat hippocampal CA1 neurons
    • Roepstorff A. and Lambert J. D. C. (1994) Factors contributing to the decay of the stimulus-evoked IPSC in rat hippocampal CA1 neurons. J. Neurophysiol. 72, 2911-2926.
    • (1994) J. Neurophysiol. , vol.72 , pp. 2911-2926
    • Roepstorff, A.1    Lambert, J.D.C.2
  • 43
    • 0027519807 scopus 로고
    • A-mediated IPSPs of rat hippocampal neurons
    • A-mediated IPSPs of rat hippocampal neurons. J. Neurophysiol. 70, 1076-1085.
    • (1993) J. Neurophysiol. , vol.70 , pp. 1076-1085
    • Rovira, C.1    Ben-Ari, Y.2
  • 44
    • 0016640871 scopus 로고
    • Characteristics of CA1 neurons recorded intracellularly in the hippocampal in vitro slice preparation
    • Schwartzkroin P. A. (1975) Characteristics of CA1 neurons recorded intracellularly in the hippocampal in vitro slice preparation. Brain Res. 85, 423-436.
    • (1975) Brain Res. , vol.85 , pp. 423-436
    • Schwartzkroin, P.A.1
  • 45
    • 0028348983 scopus 로고
    • Cellular physiology of human epilepsy
    • Schwartzkroin P. A. (1994) Cellular physiology of human epilepsy. Epilepsy Res. 17, 185-192.
    • (1994) Epilepsy Res. , vol.17 , pp. 185-192
    • Schwartzkroin, P.A.1
  • 46
    • 0028061672 scopus 로고
    • Role of the hippocampus in epilepsy
    • Schwartzkroin P. A. (1994) Role of the hippocampus in epilepsy. Hippocampus 4, 239-242.
    • (1994) Hippocampus , vol.4 , pp. 239-242
    • Schwartzkroin, P.A.1
  • 47
    • 0021332219 scopus 로고
    • Intracellular study of human epileptic cortex: In vitro maintenance of epileptiform activity
    • Schwartzkroin P. A., Knowles W. D. (1984) Intracellular study of human epileptic cortex: in vitro maintenance of epileptiform activity. Science 223, 709-712.
    • (1984) Science , vol.223 , pp. 709-712
    • Schwartzkroin, P.A.1    Knowles, W.D.2
  • 48
    • 0027048841 scopus 로고
    • Prolonged field bursts in the dentate gyrus: Dependence on low calcium, high potassium, and nonsynaptic mechanisms
    • Schweitzer J. S., Patrylo P. R. and Dudek F. E. (1992) Prolonged field bursts in the dentate gyrus: dependence on low calcium, high potassium, and nonsynaptic mechanisms. J. Neurophysiol. 68, 2016-2025.
    • (1992) J. Neurophysiol. , vol.68 , pp. 2016-2025
    • Schweitzer, J.S.1    Patrylo, P.R.2    Dudek, F.E.3
  • 49
    • 0025717405 scopus 로고
    • Permanently altered hippocampal structure, excitability, and inhibition after experimental status epilepticus in the rat: The "dormant basket cell" hypothesis and its possible relevance to temporal lobe epilepsy
    • Sloviter R. S. (1991) Permanently altered hippocampal structure, excitability, and inhibition after experimental status epilepticus in the rat: the "dormant basket cell" hypothesis and its possible relevance to temporal lobe epilepsy. Hippocampus 1, 41-66.
    • (1991) Hippocampus , vol.1 , pp. 41-66
    • Sloviter, R.S.1
  • 50
    • 0025835603 scopus 로고
    • Electrophysiology of GABA-mediated synaptic transmission and possible roles in epilepsy
    • Tasker J. G. and Dudek F. E. (1991) Electrophysiology of GABA-mediated synaptic transmission and possible roles in epilepsy. Neurochem. Res. 10, 251-265.
    • (1991) Neurochem. Res. , vol.10 , pp. 251-265
    • Tasker, J.G.1    Dudek, F.E.2
  • 51
    • 0026606661 scopus 로고
    • Local synaptic circuits and epileptiform activity in slices of neocortex from children with intractable epilepsy
    • Tasker J. G., Peacock W. J. and Dudek F. E. (1992) Local synaptic circuits and epileptiform activity in slices of neocortex from children with intractable epilepsy. J. Neurophysiol. 67, 496-507.
    • (1992) J. Neurophysiol. , vol.67 , pp. 496-507
    • Tasker, J.G.1    Peacock, W.J.2    Dudek, F.E.3
  • 52
    • 0027399109 scopus 로고
    • Correlation between function and structure in "epileptic" human hippocampal tissue maintained in vitro
    • Urban L., Aitken P. G., Crain B. J., Friedman A. H. and Somjen G. G. (1993) Correlation between function and structure in "epileptic" human hippocampal tissue maintained in vitro. Epilepsia 34, 54-60.
    • (1993) Epilepsia , vol.34 , pp. 54-60
    • Urban, L.1    Aitken, P.G.2    Crain, B.J.3    Friedman, A.H.4    Somjen, G.G.5
  • 53
    • 0029166572 scopus 로고
    • An in vitro model of persistent epileptiform activity in neocortex
    • Valenzuela V. and Benardo L. S. (1995) An in vitro model of persistent epileptiform activity in neocortex. Epilepsy Res. 21, 195-204.
    • (1995) Epilepsy Res. , vol.21 , pp. 195-204
    • Valenzuela, V.1    Benardo, L.S.2
  • 54
    • 0028868864 scopus 로고
    • Coupling potentials in CA1 neurons during calcium-free-induced field burst activity
    • Valiante T. A., Perez Velasquez J. L., Jahromi S. S. and Carlen P. L. (1995) Coupling potentials in CA1 neurons during calcium-free-induced field burst activity. J. Neurosci. 15, 6946-6956.
    • (1995) J. Neurosci. , vol.15 , pp. 6946-6956
    • Valiante, T.A.1    Perez Velasquez, J.L.2    Jahromi, S.S.3    Carlen, P.L.4
  • 55
    • 0029129378 scopus 로고
    • Erosion of inhibition contributes to the progression of low magnesium bursts in rat hippocampal slices
    • Whittington M. A., Traub R. D. and Jefferys J. G. (1995) Erosion of inhibition contributes to the progression of low magnesium bursts in rat hippocampal slices. J. Physiol. 486, 723-734.
    • (1995) J. Physiol. , vol.486 , pp. 723-734
    • Whittington, M.A.1    Traub, R.D.2    Jefferys, J.G.3
  • 56
    • 0027447036 scopus 로고
    • Monosynaptic GABA-mediated inhibitory postsynaptic potentials in CA1 pyramidal cells of hyperexcitable hippocampal slices from kainic acid-treated rats
    • Williams S., Vachon P. and LaCaille J. C. (1993) Monosynaptic GABA-mediated inhibitory postsynaptic potentials in CA1 pyramidal cells of hyperexcitable hippocampal slices from kainic acid-treated rats. Neuroscience 52, 541-554.
    • (1993) Neuroscience , vol.52 , pp. 541-554
    • Williams, S.1    Vachon, P.2    LaCaille, J.C.3
  • 57
    • 0029081545 scopus 로고
    • Prolonged GABA responses in dentate granule cells in slices isolated from patients with temporal lobe sclerosis
    • Williamson A., Telfeian A. E. and Spencer D. D. (1995) Prolonged GABA responses in dentate granule cells in slices isolated from patients with temporal lobe sclerosis. J. Neurophysiol. 74, 378-387.
    • (1995) J. Neurophysiol. , vol.74 , pp. 378-387
    • Williamson, A.1    Telfeian, A.E.2    Spencer, D.D.3
  • 58
    • 0018425019 scopus 로고
    • Dendritic mechanisms underlying penicillin-induced epileptiform activity
    • Wong R. K. and Prince D. A. (1979) Dendritic mechanisms underlying penicillin-induced epileptiform activity. Science 204, 1228-1231.
    • (1979) Science , vol.204 , pp. 1228-1231
    • Wong, R.K.1    Prince, D.A.2
  • 59
    • 0028796891 scopus 로고
    • Paroxysmal epileptiform discharges in temporal lobe slices after prolonged exposure to low magnesium are resistant to clinically used anticonvulsants
    • Zhang C. L., Dreier J. P. and Heinemann U. (1995) Paroxysmal epileptiform discharges in temporal lobe slices after prolonged exposure to low magnesium are resistant to clinically used anticonvulsants. Epilepsy Res. 20, 105-111.
    • (1995) Epilepsy Res. , vol.20 , pp. 105-111
    • Zhang, C.L.1    Dreier, J.P.2    Heinemann, U.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.