Effects of dl-3-n-butylphthalide on production of TXB2 and 6-keto- PGF(1α) in rat brain during focal cerebral ischemia and reperfusion

Acta Pharmacologica Sinica

Volumn 18, Issue 6, 1997, Pages 505-508

  Chong, Zhao Zhong ^a   Feng, Yi Pu ^a  

^a INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

6 ketoprostaglandin F1 alpha; Aspirin; dl 3 n butylphthalide; Thromboxane B2; Transient cerebral ischemia

Indexed keywords

3N BUTYLPHTHALIDE; 6 OXOPROSTAGLANDIN F1 ALPHA; ACETYLSALICYLIC ACID; PHTHALIDE DERIVATIVE; THROMBOXANE B2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN ISCHEMIA; BRAIN MICROCIRCULATION; BRAIN PROTECTION; CONTROLLED STUDY; CORPUS STRIATUM; DRUG EFFICACY; HIPPOCAMPUS; INTRAPERITONEAL DRUG ADMINISTRATION; NONHUMAN; PROSTAGLANDIN SYNTHESIS; RAT; REPERFUSION INJURY;

6-KETOPROSTAGLANDIN F1 ALPHA; ANIMALS; ASPIRIN; BENZOFURANS; BRAIN; ISCHEMIC ATTACK, TRANSIENT; NEUROPROTECTIVE AGENTS; RATS; REPERFUSION INJURY; THROMBOXANE B2;

EID: 0030736640     PISSN: 02539756     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

1. Feng YP, Hu D, Zhang LY. Effect of dl-butylphthalide (NBP) on mouse brain energy metabolism in complete brain ischemia induced by decapitation. Acta Pharm Sin 1995; 30: 741-4.
2. Liu XG, Feng YP. Protective effect of dl-3-n-butylphthalide on ischemic neurological damage and abnormal behavior in rats subjected to focal ischemia. Acta Pharm Sin 1995; 30: 896-903.
3. Lin JF, Feng YP. Effect of dl-3-n-butylphthalide on delayed neuronal damage after focal cerebral ischemia and intrasynaptosomes calcium in rats. Acta Pharm Sin 1996; 31: 166-70.
4. Kempski O, Shohami E, von Lubitz D, Hallenbeck JM, Feuerstein G. Postischemic production of eicosanoids in gerbil brain. Stroke 1987; 18: 111-9.
5. Tegtmeier F, Weber C, Heister U, Haker I, Scheller D, Nikolov R, et al. Eicosanoids in rat brain during ischemia and reperfusion correlation to DC depolarization.