Effect of pentoxifylline on the degradation of procollagen type I produced by human hepatic stellate cells in response to transforming growth factor-β1

British Journal of Pharmacology

Volumn 122, Issue 6, 1997, Pages 1047-1054

  Romanelli, Roberto Giulio ^a   Caligiuri, Alessandra ^a   Carloni, Vinicio ^a   DeFranco, Raffaella ^a   Montalto, Paolo ^a   Ceni, Elisabetta ^a   Casini, Alessandro ^a   Gentilini, Paolo ^a   Pinzani, Massimo ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Collagen degradation; Cyclic AMP; Extracellular matrix (ECM); Hepatic stellate cells (HSCs); Liver fibrosis; Matrix metalloproteinase (MMP); Pentoxifylline (PTF); Platelet derived growth factor (PDGF); Tissue inhibitor of metalloproteinase 1 (TIMP 1); Transforming growth factor 1 (TGF 1)

Indexed keywords

COLLAGEN TYPE 1; COLLAGENASE; MESSENGER RNA; PENTOXIFYLLINE; PROCOLLAGEN; PROLINE; TISSUE INHIBITOR OF METALLOPROTEINASE; TRANSFORMING GROWTH FACTOR BETA1; TRITIUM;

ARTICLE; COLLAGEN DEGRADATION; COLLAGEN SYNTHESIS; CONTROLLED STUDY; FIBROGENESIS; GENE INDUCTION; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER FIBROSIS; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION; RADIOASSAY; STELLATE CELL;

CELLS, CULTURED; COLLAGENASES; EXTRACELLULAR SPACE; HUMANS; HYDROLYSIS; LIVER; MATRIX METALLOPROTEINASE 1; PENTOXIFYLLINE; PROCOLLAGEN; RNA, MESSENGER; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TRANSFORMING GROWTH FACTORS;

EID: 0030734831     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701484     Document Type: Article

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