Comparative cytotoxicity of the aqueous chlorination products of thiobencarb, a thiocarbamate herbicide, in cultured rat hepatocytes

Toxicology in Vitro

Volumn 11, Issue 6, 1997, Pages 731-735

  Jinno, H ^a   Hanioka, N ^a   Takahashi, A ^b   Nishimura, T ^a   Toyo'Oka, T ^c   Ando, M ^a  

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^b HATANO RESEARCH INSTITUTE   (Japan)

^c UNIVERSITY OF SHIZUOKA   (Japan)

Author keywords

Chlorination products; Cytochrome P 450; Hepatotoxicity; Lipid peroxidation; Thiobencarb

Indexed keywords

BENTHIOCARB; CYTOCHROME P450; HERBICIDE;

ANIMAL CELL; ARTICLE; CHLORINATION; CONTROLLED STUDY; CYTOTOXICITY; LIPID PEROXIDATION; LIVER CELL CULTURE; LIVER TOXICITY; METABOLITE; NONHUMAN; RAT;

ANIMALIA;

EID: 0030734770     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0887-2333(97)00033-7     Document Type: Article

References (28)

1. Boyland E. and Chasseaud L. F. (1969) The role of glutathione and glutathione transferases in mercapturic acid biosynthesis. Advances in Enzymology 32, 173-219.
2. Cashraan J. R. and Olsen L. D. (1990) S-Oxygenation of thiobencarb (bolero) in hepatic preparations from striped bass (Morone saxatilis) and mammalian systems. Chemical Research in Toxicology 3, 433-440.
3. Casini A., Giorli M., Hyland R. J., Serroni A., Gilfor D. and Farber J. L. (1982) Mechanisms of cell injury in the killing of cultured hepatocytes by bromobenzene. Journal of Biological Chemistry 257, 6721-6728.
4. Cheeseman K. H. (1993) Lipid peroxidation and cancer. In DNA and Free Radicals. Edited by B. Halliwell and O. I. Aruoma. pp. 109-144. Ellis Horwood, London.
5. Fraga C. G., Leibovitz B. E. and Tappel A. L. (1987) Halogenated compounds as inducers of lipid peroxidation in tissue slices. Free Radical Biology and Medicine 3, 119-123.
6. Gonzalez F. J. (1988) The molecular biology of cytochrome P450s. Pharmacological Reviews 40, 243-288.
7. Hanioka N., Jinno H., Takahashi A., Nakano K., Yoda R., Nishimura T. and Ando M. (1995) Interaction of tetrachloroethylene with rat hepatic microsomal P450-dependent monooxygenases. Xenobiotica 25, 151-165.
8. Inomata N., Yoshida H., Aoki Y., Tsunoda M. and Yamamoto M. (1991) Effect of MCPA and other phenoxyacid compounds on hepatic xenobiotic metabolism in rats. Tohoku Journal of Experimental Medicine 165, 171-182.
9. Jauregui H. O., McMillian P. N., Hevey K. and Naik S. (1988) A quantitative analysis of lectin binding to adult rat hepatocyte cell surface. In Vitro 24, 401-412.
10. Kocarek T. A., Schuetz E. G. and Guzelian P. S. (1993) Expression of multiple forms of cytochrome P450 mRNAs in primary cultures of rat hepatocytes maintained on matrigel. Molecular Pharmacology 43, 328-334.
11. Laemmli U. K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.
12. Landers J. P. and Bunce N. J. (1991) The Ah receptor and the mechanism of dioxin toxicity. Biochemical Journal 276, 273-287.
13. Li D., Schuetz E. T. and Guzelian P. S. (1991) Hepatocyte culture in study of P450 regulation. Methods in Enzymology 206, 335-344.
14. Lowry O. H., Rosebrough N. J., Farr A. L. and Randall R. J. (1951) Protein measurement with the Folin phenol reagent. Journal of Biological Chemistry 193, 265-275.
15. Mattia C. J., Adams J. D., Jr and Bondy S. C. (1993) Free radical induction in the brain and liver by products of toluene catabolism. Biochemical Pharmacology 46, 103-110.
16. Okumura T. (1992) Degradation of pesticides in aqueous chlorine and ozone. Journal of Japan Society on Water Environment 15, 62-69.
17. Poland A., Glover E. and Kende A. S. (1976) Stereospecific, high affinity binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin by hepatic cytosol. Evidence that the binding species is receptor for induction of aryl hydrocarbon hydroxylase. Journal of Biological Chemistry 251, 4936-4946.
18. Poli G., Albano E. and Dianzani M. U. (1987) The role of lipid peroxidation in liver damage. Chemistry and Physics of Lipids 45, 117-142.
19. Saxena S. and Abdel-Rahman M. S. (1989) Pharmacodynamics of benzyl chloride in rats. Archives of Environmental Contamination and Toxicology 18, 669-677.
20. Schuetz E. G., Li D., Omiecinski C. J., Muller-Eberhard U., Kleinrnan H. K., Elswick B. and Guzelian P. S. (1988) Regulation of gene expression in adult rat hepatocytes cultured on a basement membrane matrix. Journal of Cellular Physiology 134, 309-323.
21. Seglen P. O. (1976) Preparation of isolated rat liver cells. Methods in Cell Biology 13, 29-83.
22. Takahashi Y. and Morita T. (1988) Studies on organic compounds in water (3). Organochlorine herbicides, organophosphorus pesticides and organophosphate triesters in raw and finished water. Journal of Japan Society of Water Environment 11, 161-168.
23. Takahashi Y, and Morita T. (1993) Chlorination degradation of benthiocarb in aqueous water. Journal of Japan Society of Water Environment 16, 190-201.
24. Tamura J. and Ogura N. (1994) Relationships between herbicide's fate of the river flowing into Lake Teganuma and its molecular structure. Journal of Japan Society of Water Environment 17, 247-255.
25. Towbin H., Staehelin T. and Gordon J. (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proceedings of the National Academy of Sciences of the U.S.A. 76, 4350-4354.
26. Wolf C. R., Harmon H. and Schiller C. M. (1982) Interaction of aromatic aldehydes with isolated rat liver mitochondria. Biochemical Pharmacology 31, 2025-2029.
27. Wolf C. R., Seilman S., Oesch F., Mayer R. T. and Burke M. D. (1986) Multiple forms of cytochrome P-450 related to forms induced marginally by phenobarbital. Differences in structure and in the metabolism of alkoxyresorufins. Biochemical Journal 15, 27-33.
28. Yang H. Y., Namkung M. J. and Juchau M. R. (1938) Cytochrome P-450-dependent biotransformation of a series of phenoxazone ethers in the rat conceptus during early organogenesis: evidence for multiple P-450 isoenzymes. Molecular Pharmacology 34, 67-73.