Modulation of DNA triplex stability through nucleobase modifications

Nucleosides and Nucleotides

Volumn 16, Issue 7-9, 1997, Pages 1271-1278

  Ganesh, Krishna N ^a   Rajeev, Kallanthottathil G ^a   Pallan, Pradeep S ^a   Rana, Vipul S ^a   Barawkar, Dinesh A ^a   Kumar, Vaijayanti A ^a  

^a NATIONAL CHEMICAL LABORATORY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; DNA; NUCLEIC ACID BASE; OLIGONUCLEOTIDE; POLYAMINE; SPERMINE;

CONFERENCE PAPER; CONJUGATION; MOLECULAR INTERACTION; NUCLEOTIDE METABOLISM; PROTEIN MODIFICATION; PROTON TRANSPORT;

EID: 0030734737     PISSN: 07328311     EISSN: None     Source Type: Journal    
DOI: 10.1080/07328319708006169     Document Type: Conference Paper

References (18)

1. Crooke, S.T.; Bennett, C.F. Ann. Rev. Pharmacol. Toxicol., 36, 107 (1996).
2. (a) Milligan, J.F.; Matteucci, M.D.; Martin, J.C. J. Med. Chem., 36, 1923 (1993).
3. (b) Sanghvi, Y.S.; Cook, P.D, Ed. Carbohydrate Modifications in Antisense Research, 1993, ACS Symposium Series No 580, Am. Chem. Soc., Washinton DC.
4. (a) Thuong, N.G.; Helene, C. Angew. Chem. Int. Ed. Eng. 32, 666 (1993).
5. (b) Ganesh, K.N.; Kumar, V.A.; Barawkar, D.A. In Perspectives in Supramolecular Chemistry, Vol 3, Ed. A.D.Hamilton, 1996, John Wiley & Sons.
6. (a) Thomas, T; Thomas, T.J. Biochemistry, 32, 14068 (1993).
7. (b) Tung, C.H.; Breslauer, K.J.; Stein, S. Nucleic Acids Res. 21, 5489 (1993)
8. (a) Barawkar, D.A.; Kumar, V.A.; Ganesh, K.N. Biochem. Biophys. Res. Comm. 205, 1665 (1994).
9. (b) Barawkar, D.A.; Rajeev, K.G.; Kumar, V.A.; Ganesh, K.N. Nucleic Acids Res. 24, 1229 (1996).
10. Inman, R.B. J. Mol. Biol. 9, 624 (1964).
11. Ganesh, K.N.; Kumar, V.A.; Barawkar, D.A.; Rajeev, K.G.; Rana, V.S. Pure & Appl. Chem., 1997 (in press).
12. Hashimoto, H; Nelson, M.G.; Switzer, C. J. Am. Chem. Soc. 115, 7128 (1993).
13. Pallan, P.S.; Ganesh, K.N. Biochem. Biophys. Res. Comm. 222, 416 (1996).
14. Rana, V.S.; Barawkar, D.A.; Ganesh, K.N. J. Org. Chem. 61, 3578 (1996).
15. (a) Trapane, T.L.; Christopherson, M.S.; Coby, C.D.; Ts'O, P.O.P.; Wang, D. J. Am. Chem. Soc. 116, 8412 (1994).
16. (b) Bandaru, R.; Hashimoto, H.; Switzer, C. J. Org. Chem. 60, 786 (1995).
17. (a) Perales, J.C.; Ferkol, T.; Molas, M.; Hanson, R.W. Eur. J. Biochem. 226, 255 (1994)
18. (b) Bergeron, R.J.; Weimar, W. R.; Wu, Q.; Austin, Jr. J.K.; McManis, S.; J. Med. Chem. 38, 425 (1995).