Stimulatory effect of synthetic luminal cholecystokinin releasing factor (LCRF) fragment (1-35) on pancreatic exocrine secretion in conscious rats

Pancreas

Volumn 15, Issue 3, 1997, Pages 310-313

  Miyasaka, Kyoko ^a   Funakoshi, Akihiro ^b  

^a TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

^b NATIONAL KYUSHU CANCER CENTER   (Japan)

Author keywords

CCK; CCK releasing peptide; CCK A receptor; Luminal cholecystokinin (CCK) releasing factor fragment; Rat

Indexed keywords

CHOLECYSTOKININ; CHOLECYSTOKININ A RECEPTOR; POLYPEPTIDE; SYNTHETIC PEPTIDE;

ANIMAL EXPERIMENT; ARTICLE; CONSCIOUSNESS; CONTROLLED STUDY; MALE; MUTANT; NONHUMAN; PANCREAS SECRETION; PRIORITY JOURNAL; RAT;

EID: 0030734723     PISSN: 08853177     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006676-199710000-00015     Document Type: Article

References (23)

1. Green GM, Lyman RL. Feedback regulation of pancreatic enzyme secretion as a mechanism for trypsin inhibitor-induced hypersécré tion in rats. Proc Soc Exp Biol Med 1972;140:6-12.
2. Louie D, May D, Miller P, Owyang C. Cholecystokinin mediates feedback regulation of pancreatic enzyme secretion in rats. Am J Physiol 1986;250:G252-9.
3. Fölsch UR, Cantor P, Wilms HM, Schafmayer A, Becker HD, Creutzfeldt W. Role of Cholecystokinin in the negative feedback control of pancreatic enzyme secretion in conscious rats. Gastroenterology 1987;92:449-58.
4. Nakamura R, Miyasaka K, Funakoshi A, Kitani K. Interactions between bile and pancreatic juice diversions on Cholecystokinin release and pancreas in conscious rats. Proc Soc Exp Biol Med 1989;192:182-6.
5. Miyasaka K, Green GM. Effect of rapid washout of proximal small intestine on pancreatic secretion in conscious rat. Gastroenterology 1983;84:1251 (abstract).
6. Lu L, Louie D, Owyang C. A cholecystokinin-releasing peptide mediates feedback regulation of pancreatic secretion. Am J Physiol 1989;256:G430-5.
7. Miyasaka K, Guan D, Liddle RA, Green GM. Feedback regulation by trypsin: evidence for intramular CCK-reading peptide. Am J Physiol., 1989:257:G175-81.
8. Miyasaka K, Funakoshi A. Isolation and bioactivity of putative cholecystokmm-releasing peptide from rat small intestinal mucosa J Gastroenterol 1992;27:83-7.
9. Spannagel AW, Green GM, Guan D, Liddle RA, Fault K, Reeve UR. Purification and characterization of a luminal cholecystokininreleasing factor from rat intestinal secretion. Proc Natl Acad Sei USA 1996;93:4415-20.
10. Funakoshi A, Miyasaka K, Jimi A, Kawanami T, Takata Y, Kono A. Little or no expression of the cholecystokinin-A receptor gene in the pancreas of diabetic rats (Otsuka Long-Evans Tokushima Fatty-OLETF rats). Biochem Biophys Res Commun 1994;199: 482-8.
11. Funakoshi A, Miyasaka K, Shinozaki H, et al. An animal model of congenital defect of gene expression of cholecystokinin (CCK)-A receptor. Biochem Biophys Res Commun 1995;210:787-96.
12. Miyasaka K, Kanai S, Ohta M, Kawanami T, Kono A, Funakoshi A. Lack of satiety effect of cholecystokinin (CCK) in a new rat model not expressing the CCK-A receptor gene. Neurosci Lett 1994;180:143-6.
13. Miyasaka K, Masuda M, Kawanami T, Funakoshi A. Neurohormonal regulation of pancreatic exocrine function in rats without gene expression of cholecystokinin-A receptor. Pancreas 1996; 12: 230-6.
14. Funakoshi A, Miyasaka K, Shinozaki H, Arita Y, Nakano I, Nawata H. Regulation of pancreatic exocrine function in Otsuka Long-Evans Tokushima Fatty (OLETF) rats without gene expression of cholecystokinin-A receptor. Intern Med 1996:35:249-56.
15. Miyasaka K, Funakoshi A, Nakamura R, et al. Differences in stimulatory effects between rat pancreatic secretory trypsin inhibitor-61 and -56 on rat pancreas. Jpn J Physiol 1989;39:891-9.
16. Miyasaka K, Funakoshi A, Shikado F, Uda K, Kitani K. Inhibitory effect of taurocholate on CCK release and pancreatic secretion produced by two CCK-releasing peptide in conscious rats. Pancreas 1992;7:536-42.
17. Keller PJ, Cohen E, Neurath H. The proteins of bovine pancreatic juice. J Biol Chem 1958;233:344-9.
18. Iwai K, Fukuoka S, Fushiki T, et al. Purification and sequencing of a trypsin-sensitive cholecystokinin-releasing peptide from pancreatic juice. J Biol Chem 1987;262:8956-9.
19. Miyasaka K, Sazaki N, Funakoshi A, Matsumoto M, Kitani K. Two mechanisms of inhibition by bile on luminal feedback regulation of rat pancreas. Gastroenterology 1993;104:1780-5.
20. Miyasaka K, Funakoshi A. Effects of recombinant pancreatic secretory trypsin inhibitors on pancreatic exocrine secretion in conscious rats. J Jpn Paner Soc 1993;8:170-5 (in Japanese with English abstract).
21. Moran TH, Norgren R, Crosby RJ, McHugh PR. Central and peripheral vagal transport of cholecystokinin binding sites occurs in afferent fibers. Brain Res 1990;526:95-102.
22. Li Y, Owyang C. Vagal afferent pathway mediates physiological action of cholecystokinin on pancreatic enzyme secretion, din Invest 1993;92:418-24.
23. Li P, Lee KY, Chang TM, Chey WY. Mechanism of acid-induced release of secretin in rats. Presence of a secretin-releasing peptide. J Clin Invest 1990;86:1474-9.