A novel and economical synthesis of 2'-O-alkyl-uridines

Nucleosides and Nucleotides

Volumn 16, Issue 7-9, 1997, Pages 1641-1643

  Ross, Bruce S ^a   Springer, Robert H ^a   Tortorici, Zeb ^a   Dimock, Stuart ^a  

^a ISIS PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PYRIMIDINE DERIVATIVE; URIDINE DERIVATIVE;

ALKYLATION; ANALYTIC METHOD; CHIMERA; CHROMATOGRAPHY; CONFERENCE PAPER; DRUG SYNTHESIS; ECONOMIC ASPECT; METHYLATION; NONHUMAN;

EID: 0030734350     PISSN: 07328311     EISSN: None     Source Type: Journal    
DOI: 10.1080/07328319708006245     Document Type: Conference Paper

References (9)

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2. For examples see a) Inoue, H.; Hayase, H.; Imura, A.; Iwai, S.; Miura, K. Ohtsuka, E. Nuc.leic Adds Res. 1987, 15, 6131. b) Wagner, D.; Verheyden, J.; Moffat, J. J. Org. Chem. 1974, 39, 24. c) Chavis, C.; Dumont, F.; Wightman, R.; Ziegler, J.; Imbach, J.L.J. Org. Chem. 1982, 47, 202.
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9. We wish to thank Professors Morris J. Robins and Michael Jung for their helpful discussions regarding this reaction and potential mechanisms.