Successful control of Clostridium difficile infection in an elderly care unit through use of a restrictive antibiotic policy

Journal of Antimicrobial Chemotherapy

Volumn 40, Issue 5, 1997, Pages 707-711

  McNulty, Cliodna ^a   Logan, Margaret ^a   Donald, I P ^a   Ennis, Debbie ^b   Taylor, Denise ^a   Baldwin, R N ^a   Bannerjee, Mira ^a   Cartwright, K A V ^a  

^a GLOUCESTERSHIRE ROYAL HOSPITAL   (United Kingdom)

^b BIRMINGHAM HEARTLANDS HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; CEFUROXIME; CEPHALOSPORIN DERIVATIVE; GENTAMICIN; PENICILLIN G; TRIMETHOPRIM;

AGED; ARTICLE; BACTERIAL INFECTION; CLOSTRIDIUM DIFFICILE; DIARRHEA; ELDERLY CARE; HAEMOPHILUS INFLUENZAE; HEALTH CARE COST; HEALTH CARE POLICY; HOSPITALIZATION; HUMAN; INFECTION CONTROL; INTRAVENOUS DRUG ADMINISTRATION; MAJOR CLINICAL STUDY; MORTALITY; SEPTIC SHOCK; STREPTOCOCCUS INFECTION; URINARY TRACT INFECTION;

EID: 0030734254     PISSN: 03057453     EISSN: None     Source Type: Journal    
DOI: 10.1093/jac/40.5.707     Document Type: Article

References (21)

1. Wilcox, M. H. (1996). Cleaning up Clostridium difficile infection. Lancet 348, 767-8.
2. Department of Health and Public Health Laboratory Service Joint Working Group. (1994). Clostridium difficile infection. Prevention and Management. BAPS Health Publication Unit, DSS Distribution Centre, Heywood , Lancashire.
3. Tabagchali, S. & Jumaa, P. (1995). Diagnosis and management of Clostridium difficile infection. British Medical Journal 310, 1375-80.
4. Riley, T. V., Codde, J. P. & Rouser, I. L. (1995). Increased length of hospital stay due to Clostridium difficile associated diarrhoea. Lancet 345, 455-6.
5. McFarland, L. V., Mulligan, M. E., Kwok, R. Y. & Stamm, N. E. (1989). Nosocomial acquisition of Clostridium difficile infection. New England Journal of Medicine 320, 204-10.
6. Kelly, C. P., Pothoulakis, C. & Lamont, J. T. (1994). Clostridium difficile colitis. New England Journal of Medicine 330, 257-62.
7. Impallomeni, M., Galletly, N. P., Wort, S. J., Starr, J. M. & Rogers, T. R. (1995). Increased risk of diarrhoea caused by Clostridium difficile in elderly patients receiving cefotaxime.. British Medical Journal 311, 1345-6.
8. Cartmill, T. D. I., Panigrahi, H., Worsley, M. A., McCann, D. C., Nice, C. N. & Keith, E. (1994). Management and control of a large outbreak of diarrhoea due to Clostridium difficile. Journal of Hospital Infection 27, 1-15.
9. Harrison, B. D. N., Farr, B. M., Connolly, C. K., Macfarlane, J. T., Selkon, J. B. & Bartlett, C. L. R. (1987). The hospital management of community-acquired pneumonia. Journal of the Royal College of Physicians 21, 267-9.
10. British Thoracic Society. (1993). Guidelines for the management of community-acquired pneumonia in adults admitted to hospital. British Journal of Hospital Medicine 49, 346-50.
11. Starr, J. M., Rogers, T. M. & Impallomeni, M. (1997). Hospital-acquired Clostridium difficile diarrhoea and herd immunity. Lancet 349, 426-8.
12. Anand, A., Bashey, B., Mir, T. & Glatt, A. E. (1994). Epidemiology, clinical manifestations and outcome of Clostridium difficile-associated diarrhoea. American Journal of Gastroenterology 89, 519-23.
13. Bartram, J. D., Dusntan, F. D. J., Hill, D., Hosein, I. K. & Pippen, C. A. R. (1995). Clostridium difficile: the association between antibiotic therapy and the incidence of infection in the elderly. Pharmaceutical Journal 255, 276-8.
14. Brazier, J. S. (1993). The laboratory diagnosis of Clostridium difficile diarrhoea. PHLS Microbiology Digest 10, 79-81.
15. Hoffman, P. N. (1993). Clostridium difficile diarrhoea and the hospital environment. PHLS Microbiology Digest 10, 91-2.
16. Communicable Disease Report Weekly (1997). Volume 7, p. 34.
17. Macfarlane, J. T., Finch, R. G., Ward, M. J. & McCrae, A. D. (1982). Hospital study of adult community-acquired pneumonia. Lancet ii, 255-8.
18. Chattopadhyay, B. (1995). Clostridium difficile diarrhoea. Journal of Hospital Infection 29, 75-7.
19. Li, S. C., loannides-Demos, L. L., Spicer, W. J., Berbatis, C., Spelman, D. W. N., Tong, N. et al. (1989). Prospective audit of aminoglycoside usage in a general hospital with assessments of clinical processes and adverse clinical outcomes. Medical Journal of Australia 151, 224-32.
20. Nicolau, D. P., Freeman, C. D., Belliveau, P. P., Nightingale, C. H., Ross, J. W. & Quintiliani, R. (1995). Experience with a once-daily aminoglycoside program administered to 2,184 adult patients. Antimicrobial Agents and Chemotherapy 39, 650-5.
21. Burman, L. A., Trollfors, B., Andersson, B., Henrichsen, J., Juto, P., Kalllings, I. et al. (1991). Diagnosis of pneumonia by cultures, bacterial and viral antigen detection tests, and serology with special reference to antibodies against pneumococcal antigens. Journal of Infectious Diseases 163, 1087-93.