Localization and characterization of stannin: Relationship to cellular sensitivity to organotin compounds

Neurochemistry International

Volumn 31, Issue 6, 1997, Pages 801-815

  Dejneka, Nadine S ^a   Patanow, Christine M ^a   Polavarapu, Rathnagiri ^a   Toggas, Stephanie M ^a   Krady, J Kyle ^a   Billingsley, Melvin L ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN PROTEIN; COMPLEMENTARY DNA; MESSENGER RNA; ORGANOTIN COMPOUND;

ANIMAL TISSUE; ARTICLE; BACULOVIRUS; BRAIN DEVELOPMENT; CEREBELLUM; CHROMATOGRAPHY; CORPUS STRIATUM; HEART; HIPPOCAMPUS; IMMUNOBLOTTING; IN SITU HYBRIDIZATION; KIDNEY; LIVER; LUNG; MALE; MESENCEPHALON; MOLECULAR BIOLOGY; NEOCORTEX; NEUROTOXICITY; NEWBORN; NONHUMAN; NORTHERN BLOTTING; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PURIFICATION; RAT; RNA TRANSCRIPTION; SKELETAL MUSCLE; SPLEEN; TESTIS;

ANIMALS; B-LYMPHOCYTES; BACULOVIRIDAE; BLOTTING, NORTHERN; BLOTTING, WESTERN; BRAIN; GENE EXPRESSION; GENETIC VECTORS; IN SITU HYBRIDIZATION; MALE; NEUROPEPTIDES; ORGANOTIN COMPOUNDS; RATS; RATS, SPRAGUE-DAWLEY; SPLEEN; SUBCELLULAR FRACTIONS; T-LYMPHOCYTES;

ANIMALIA; RODENTIA; UNIDENTIFIED BACULOVIRUS;

EID: 0030733292     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0197-0186(97)00034-X     Document Type: Article

References (25)

1. Balaban, C. D., O'Callaghan, J. P. and Billingsley, M. L. (1988) Trimethyltin-induced neuronal damage in the rat brain: comparative studies using silver degeneration stains, immunocytochemistry and immunoassay for neuronotypic and gliotypic proteins. Neuroscience 26, 337-361.
2. Boyer, I. J. (1989) Toxicity of dibutyltin, tributyltin and other organotin compounds to humans and to experimental animals. Toxicology 55(3), 253-298.
3. Brown, A. W., Aldridge, W. N., Street, B W. and Verschoyle, R. D. (1979) The behavioral and neuropathologic sequalae of intoxication by trimethyltin compounds in the rat. Am. J. Path. 97, 59-82.
4. Brown, A. W., Cavanagh, J. B., Verschoyle, R. D., Gsybers, M. F., Jones, H. B. and Aldridge, W. N. (1984) Evolution of the intracellular changes in neurons caused by trimethyltin. Neuropath. Appli. Neurobiol. 10, 267-283.
5. Cathala, G., Savouret, J. F., Mendez, B., West, B. L., Karin, M., Martial, J. A. and Baxter, J. D. (1983) A method for isolation of intact, translationally active ribonucleic acid. DNA 2, 329-335.
6. Cook, L. L., Stine, K. E. and Reiter, L. W. (1984) Tin distribution in adult rat tissues after exposure to trimethyltin and triethyltin. Toxicol. Appl. Pharmacol. 76, 344-348.
7. Dyer, R. S., Walsh, T. J., Wonderlin, W. F. and Bercegeay, M. (1982) The trimethyltin syndrome in rats. Neurobehav. Toxicol. Teratol. 4, 127-133.
8. Ghosh, B. B., Talukder, G. and Sharma, A. (1989) Cytotoxic effects of trimethyltin chloride on human peripheral blood lymphocytes in vitro. Human Toxicol. 8, 349-353.
9. Harris, K. A., Oyler, G. A., Doolittle, G. M., Vincent, I., Lehman, R. A. W., Kincaid, R. L. and Billingsley, M. L. (1993) Okadaic acid induces hyperphosphorylated forms of tau protein in human brain slices. Anal, of Neurol. 33, 77-87.
10. Krady, J. K., Oyler, G. A., Balaban, C. D. and Billingsley, M. L. (1990) Use of avidin-biotin subtractive hybridization to characterize mRNA common to neurons destroyed by the selective neurotoxicant trimethyltin. Mol. Brain. Res. 7, 287-297.
11. McMillan, D. E. and Wenger, G. R. (1985) Neurobehavioral toxicology of trialkyltins. Pharmacol. Rev. 37, 365-379.
12. Merril, C. R., Bisher, M. E., Harrington, M. and Steven, A. C. (1988) Coloration of silver-stained protein bands in polyacrylamide gels is caused by light scattering from silver grains of characteristic sizes. Proc. Natl. Acad. Sci. 85, 453-457.
13. Nolan, C. C., Brown, A. W. and Cavanagh, J. B. (1990) Regional variations in nerve cell responses to trimethyltin intoxication in Mongolian gerbils and rats; further evidence for involvement of the Golgi apparatus. Acta Neuropath. 81, 204-212.
14. O'Callaghan, J. P. (1988) Neurotypic and gliotypic proteins as biochemical markers of neurotoxicity. Neurotoxicol. Teratol. 10(5), 445-452.
15. Opacka, J. and Sparrow, S. (1985) Nephrotoxic effect of tritnethyltin in rats. Toxicol. Lett. 27, 97-102.
16. Oyler, G. A., Higgins, G. A., Hart, R. A., Battenberg, E., Billingsley, M. L., Bloom, F. E. and Wilson, M. C. (1989) The identification of a novel synaptosomal-associated protein, SNAP-25, differentially expressed by neuronal subpopulations. J. Cell Biol. 109, 3039-3052.
17. Patanow, C. M., Day, J. R. and Billingsley, M. L. (1997) Alteration in hippocampal expression of SNAP-25, GAP-43, stannin and glial fibrillary acidic protein following mechanical and trimethyltin-induced injury in the rat. Neuroscience 76, 187-202.
18. Polli, J. W., Billingsley, M. L. and Kincaid, R. L. (1991) Expression of the calmodulin-dependent protein phosphatase, calcineurin, in rat brain: developmental patterns and the role of nigrostriatal innervation. Dev. Brain Res. 63, 105-119.
19. Sambrook, J., Fritsch, E. F. and Maniatis, T. (1989) Molecular Cloning, 2nd edn. Cold Spring Harbor Laboratory Press, New York.
20. Snoeij, N. J., Penninks, A. H. and Seinen, W. (1987) Biological activity of organotin compounds-an overview. Environmental Res. 44, 335-353.
21. Snoeij, N. J., Van Iersel, A. A. J., Penninks, A. H. and Seinen, W. (1986) Triorganotin-induced cytotoxicity to rat thymus, bone marrow and red blood cells as determined by several in vitro assays. Toxicol. 39, 71-83.
22. Thompson, T. A., Lewis, J. M., Dejneka, N. S., Severs, W. B., Polavarapu, R. and Billingsley, M. L. (1996) Induction of apoptosis by organotin compounds in vitro: neuronal protection with antisense oligodeoxy nucleotids directed against stannin. J. Pharmacol. Exper. Therapu. 276, 1201-1215.
23. Toggas, S. M., Krady, J. K. and Billingsley, M. L. (1992) Molecular neurotoxicology of trimethyltin: identification of stannin, a novel protein expressed in trimethyltin-sensitive cells. Mol. Pharmacol. 42, 44-56.
24. Toggas, S. M., Krady, J. K., Thompson, T. A. and Billingsley, M. L. ( 1993) Molecular mechanisms of selective neuro-toxicants: studies on organotin compounds. Anal. N.Y. Acad. Sci. 679, 157-177.
25. Van Eldik, L. J. and Wolchok, S. R. (1984) Conditions for reproducible detection of calmodulin and S100 beta in immunoblots. Biochem. Biophys. Res. Commun. 124, 752-759.