Effects of volatile anaesthetics on spontaneous action potential firing of cerebellar Purkinje cells in vitro do not follow the Meyer-Overton rule

British Journal of Anaesthesia

Volumn 79, Issue 5, 1997, Pages 617-624

  Antkowiak, B ^a   Hentschke, H ^a   Kirschfeld, K ^a  

^a MAX PLANCK INSTITUTE FOR BIOLOGICAL CYBERNETICS   (Germany)

Author keywords

Anaesthetics volatile, enflurane; Anaesthetics volatile, halothane; Anaesthetics volatile, isoflurane; Brain, cerebellum; Brain, Purkinje neurones; Theories of anaesthetic action, Meyer Overton

Indexed keywords

ENFLURANE; HALOTHANE; INHALATION ANESTHETIC AGENT; ISOFLURANE;

ACTION POTENTIAL; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CEREBELLUM; CONTROLLED STUDY; FEMALE; MALE; NERVE POTENTIAL; NONHUMAN; PRIORITY JOURNAL; PURKINJE CELL; RAT; SPIKE; SPIKE WAVE;

EID: 0030732434     PISSN: 00070912     EISSN: None     Source Type: Journal    
DOI: 10.1093/bja/79.5.617     Document Type: Article

References (38)

1. Overton E. Studien über die Narkose zugleich ein Beitrag zur allgemeinen Pharmakologie. Jena: Fischer, 1901.
2. Eger EI II, Saidmann LJ, Brandstater B. Minimum alveolar concentration, a standard of anesthetic potency. Anesthesiology 1965; 26: 756-763.
3. Franks NP, Lieb WR. Molecular and cellular mechanisms of general anaesthesia. Nature (London) 1994; 367: 607-614.
4. Rampil IJ, Mason P, Singh H. Anesthetic potency (MAC) is independent of forebrain structures in the rat. Anesthesiology 1993; 78: 707-712.
5. Collins JG, Kending JJ, Mason P. Anesthetic actions within the spinal cord: contributions to the state of general anesthesia. Trends in Neurosciences 1995; 12: 549-553.
6. Richards CD, White AE. Effects of volatile anaesthetics on synaptic transmission in the dentate gyrus. Journal of Physiology (London) 1975; 252: 241-257.
7. Yoshimura M, Higashi H, Fujita S, Shimoji K. Selective depression of hippocampal inhibitory postsynaptic potentials and spontaneous firing by volatile anaesthetics. Brain Research 1985; 340: 363-368.
8. Fujiwara N, Higashi S, Nishi S, Shimoto K, Sugita S, Yoshimura M. Changes in spontaneous firing patterns of rat hippocampal neurones induced by volatile anaesthetics. Journal of Physiology (London) 1988; 402: 155-175.
9. MacIver MB, Kending JJ. Enflurane-induced burst discharge of hippocampal CA1 neurones is blocked by the NMDA receptor antagonist APV. British Journal of Anaesthesia 1989; 63: 296-305.
10. Miu P, Puil E. Isoflurane-induced impairment of synaptic transmission in hippocampal neurons. Experimental Brain Research 1989; 75: 354-360.
11. Berg-Johnsen J, Langmoen IA. Mechanisms concerned in the direct effect of isoflurane on rat hippocampal and human neocortical neurons. Brain Research 1990; 507: 28-34.
12. El-Beheiry H, Puil E. Postsynaptic depression induced by isoflurane and Althesin in neocortical neurons. Experimental Brain Research 1989; 75: 361-368.
13. Sugiyama K, Muteki T, Shimoji K. Halothane-induced hyperpolarization and depression of postsynaptic potentials of guinea pig thalamic neurons in vitro. Brain Research 1992; 575: 97-103.
14. Ries CR, Puil E. Isoflurane prevents transitions to tonic and burst firing modes in thalamic neurons. Neuroscience Letters 1993; 159: 91-94.
15. Richards CD, Russell WJ, Smaje JC. The action of ether and methoxyflurane on synaptic transmission in isolated preparations of the mammalian cortex. Journal of Physiology (London) 1975; 59: 121-142.
16. Scholfield CN. Potentiation of inhibition by general anaesthetics in neurones of the olfactory cortex in vitro. Pflugers Archiv 1980; 383: 249-255.
17. + current. Nature (London) 1988; 333: 662-664.
18. Langmoen IA, Larsen M, Berg-Johnsen J. Volatile anaesthetics: cellular mechanisms of action. European Journal of Anaesthesiology 1995; 12: 51-58.
19. Elliott JR, Urban BW. Integrative effects of general anaesthetics: why nerve axons should not be ignored. European Journal of Anaesthesiology 1995; 12: 41-50.
20. Richards CD. The synaptic basis of general anaesthesia. European Journal of Anaesthesiology 1995; 12: 5-19.
21. A receptor/chloride channel complex in anesthesia. Anesthesiology 1993; 78: 757-776.
22. Llinas R, Sugimori M. Electrophysiological properties of in vitro Purkinje cell somata in mammalian cerebellar slices. Journal of Physiology (London) 1980; 305: 171-195.
23. Llinas R, Sugimori M. Electrophysiological properties of in vitro Purkinje cell dendrites in mammalian cerebellar slices. Journal of Physiology (London) 1980; 305: 197-213.
24. Jaeger D, Bauer JM. Prolonged responses in rat cerebellar Purkinje cells following activation of the granule cell layer: an intracellular in vitro and in vivo investigation. Experimental Brain Research 1994; 100: 200-214.
25. Mazze RI, Rice SA, Baden JM. Halothane, isoflurane and enflurane MAC in pregnant and nonpregnant female and male mice and rats. Anesthesiology 1985; 62: 339-341.
26. Edwards FA, Konnerth A, Sakmann B, Takahashi T. A thin slice preparation for patch clamp recordings from neurones of the mammalian central nervous system. Pflugers Archiv 1989; 441: 85-100.
27. Kawaguchi Y. Groupings of nonpyramidal and pyramidal cells with specific physiological and morphological characteristics in rat cortex. Journal of Neurophysiology 1993; 69: 416-431.
28. Hirsch JA. Synaptic integration in layer IV of the ferret striate cortex. Journal of Physiology (London) 1995; 483: 183-199.
29. Wakamori M, Ikemoto Y, Akaike N. Effects of two volatile anaesthetics and a convulsant on excitatory and inhibitory amino acid responses in dissociated CNS neurons of the rat. Journal of Neurophysiology 1991; 66: 2014-2021.
30. Franks NP, Lieb WR. Selective actions of volatile general anaesthetics at molecular and cellular levels. British Journal of Anaesthesia 1993; 71: 65-76.
31. Russell GB, Graybeal JM. Differences in anaesthetic potency between Sprague-Dawley and Long-Evans rats for isoflurane but not nitrous oxide. Pharmacology 1995; 50: 162-167.
32. Rampil IJ, Laster MJ. No correlation between quantitative electroencephalographic measurements and movement response to noxious stimuli during enflurane anesthesia in rats. Anesthesiology 1992; 77: 920-925.
33. Kissin I, Morgan PL, Smith LR. Anesthetic potencies of isoflurane, halothane and diethyl ether for various endpoints of anesthesia. Anesthesiology 1983; 58: 88-92.
34. Nicoll RA, Madison DV. General anesthetics hyperpolarize neurons in the vertebrate central nervous system. Science 1982; 217: 1055-1056.
35. Franks NP, Lieb WR. Molecular mechanisms of general anaesthesia. Nature (London) 1982; 300: 487-493.
36. Forman SA, Miller KW. Molecular sites of anesthetic action in postsynaptic nicotinic membranes. Trends in Pharmacological Sciences 1989; 10: 447-452.
37. Franks NP, Lieb WR. Selective actions of volatile general anaesthetics at molecular and cellular levels. British Journal of Anaesthesia 1993; 71: 65-76.
38. A-mediated inhibition of Purkinje cells in rat cerebellar slices. Journal of Neurophysiology 1997; 77: 2525-2538.