Calpain, a mediator of myelin breakdown in demyelinating diseases

Annals of the New York Academy of Sciences

Volumn 825, Issue , 1997, Pages 128-130

  Shields, Donald C ^a   Deibler, Gladys E ^a   Banik, Naren L ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALPAIN; MYELIN PROTEIN; PROTEINASE; STRUCTURAL PROTEIN;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ASTROCYTE; CONFERENCE PAPER; CONTROLLED STUDY; DEMYELINATING DISEASE; NONHUMAN; OPTIC NERVE; PROTEIN DEGRADATION; PROTEIN TRANSPORT; RAT; SPINAL CORD;

ANIMALIA;

EID: 0030732399     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1997.tb48422.x     Document Type: Conference Paper

References (7)

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2. SHIELDS, D. C., C. LEBLANC & N. L. BANIK. 1996. Calpain activation in optic nerve. J. Neurochem. 66(1): 89.
3. LUCAS, J. et al. 1992. Susceptibility of myelin proteins to a neutral endoproteinase: the degradation of myelin basic protein (MBP) and P2 protein by purified bovine brain multicatalytic proteinase complex (MPC). Neurochem. Res. 17(12): 1261-1266.
4. SHEARER, T. R. & L. L. DAVID. 1990. Calpains in lens and cataract. In Intracellular Calcium-Dependent Proteolysis. R. L. Mellgren & T. Murachi, Eds. 265-276. CRC Press. Boca Raton, FL.
5. BARTUS, R., et al. 1995. Calpain inhibitor AK295 protects neurons from focal brain ischemia: effects of post-occlusion intra-arterial administration. Stroke 25: 2265-2270.
6. NIXON, R. A. 1986. Fodrin degradation by calcium-activated neutral proteinase (CANP) in retinal ganglion cell neurons and optic glia: preferential localization of CANP activated in neurons. J. Neurosci. 6: 1264-1271.
7. LAEMMLE, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T. Nature 227: 680-685.