Insulin sensitivity and beta-cell function in essential hypertension and normotensive first-degree relatives of hypertensive subjects

Diabetes and Metabolism

Volumn 23, Issue 5, 1997, Pages 402-408

  Cabezas Cerrato, J ^a,b   Garcia Estevez, D A ^b   Araujo Vilar D ^b  

^a HOSPITAL CLÍNICO UNIVERSITARIO   (Spain)

^b UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

Calcium antagonist; Dyslipidaemia; Essential hypertension; Insulin resistance; Offspring of hypertensive subjects

Indexed keywords

NITRENDIPINE;

ADULT; ARTICLE; CLINICAL ARTICLE; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; ESSENTIAL HYPERTENSION; FAMILIAL DISEASE; FEMALE; HUMAN; INSULIN RESISTANCE; INTRAVENOUS GLUCOSE TOLERANCE TEST; MALE; PANCREAS ISLET CELL TUMOR;

ADULT; AGE FACTORS; ANALYSIS OF VARIANCE; ANTIHYPERTENSIVE AGENTS; BLOOD GLUCOSE; BODY MASS INDEX; CHOLESTEROL; CHOLESTEROL, HDL; CHOLESTEROL, LDL; FASTING; FEMALE; GLUCOSE TOLERANCE TEST; HUMANS; HYPERTENSION; INSULIN; ISLETS OF LANGERHANS; MALE; MODELS, BIOLOGICAL; NITRENDIPINE; PARENTS; REFERENCE VALUES; TRIGLYCERIDES;

EID: 0030732017     PISSN: 03381684     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. The Working Group on Hypertension in Diabetes. Statement on hypertension in diabetes mellitus. Arch Intern Med, 1987, 147, 830-842.
2. Pollare T, Lithel H, Selinus I, Berne C. Sensitivity to insulin during treatment with atenolol and metoprolol : a randomized, double blind study of effects on carbohydrate and lipoprotein metabolism in hypertensive patients. BMJ, 1989, 298, 1152-1157.
3. Pollare T, Lithell H, Berne C. A comparison of the effects of hydroclorothiazide and captopril on glucose and lipid metabolism in patients with hypertension. N Engl J Med, 1989,321, 868-873.
4. Pollare T, Lithel H, Selinus I, Berne C. Application of prazosin is associated with increase of insulin sensitivity in obese patients with hypertension. Diabetologia, 1988, 31, 415-420.
5. Draznin B, Sussman KE, Eckel RH, Kao M, Yost T, Sherman NA. Possible role of cytosolic free calcium concentration in mediating insulin resistance of obesity and hyperinsulinemia. J Clin Invest, 1988, 82, 1848-1852.
6. Foot EA, Leighton B. Effects of calcium antagonists on insulinmediated glucose metabolism in skeletal muscle. Diabetes, 1994, 43, 73-79.
7. Pollare T, Lithell H, Morlin C, Prantare H, Hvarfner A, Ljunghall S. Metabolic effects of diltiazem and atenolol : results from a randomized, double-blind study with parallel groups. J Hypert, 1989, 7, 551-559.
8. Pershadsingh HA, Grant N. Association of diltiazem therapy with increased insulin resistance in patients with type I diabetes mellitus. JAMA, 1987, 257, 931-932.
9. Ferrannini E, Buzzigoli G, Bonadonna R, et al.. Insulin resistance in essential hypertension. N Engl J Med, 1987, 317, 350-357.
10. Raven GM. Role of insulin resistance in human disease. Diabetes, 1988, 37, 1495-1607.
11. Fontbonne A, Thibult N, Eschewège E, Ducimetière P. Body fat distribution and coronary heart disease mortality in subjects with impaired glucose tolerance or diabetes mellitus : the Paris Prospective Study, 15-year follow-up. Diabetologia, 1992, 35, 464-468.
12. Ferrari P, Weidmann P, Shaw S, Giachino D. Altered insulin sensitivity, hyperinsulinaemia and dyslipidaemia in individuals with a hypertensive parent. Am J Med, 1991, 91, 589-596.
13. Stern MP. The insulin resistance syndrome : the controversy is dead, long live the controversy ! Diabetologia, 1994, 37, 956-958.
14. Bonora E, Bonadonna RC, Del Prato S, et al. In vivo glucose metabolism in obese and type II diabetic subjects with or without hypertension. Diabetes, 1993, 42, 764-772.
15. Cabezas-Cerrato J, García-Estévez D.A., Araújo D, Iglesias Guerrero M. Insulin sensitivity, glucose effectiveness and beta cell function in obese males with essential hypertension : Investigation of the effects of treatment with a calcium channel blocker (diltiazem) or an ACE-inibitor (quinapril). Metabolism, 1997, 46, 173-78.
16. Moller DE, Flier JS. Insulin resistance : mechanism, syndromes, and implications. N Engl J Med, 1991, 26, 938-948.
17. Bergman RN, Ider YZ, Bowden CR, Cobelli C. Quantitative estimation of insulin sensitivity. Am J Physiol, 1979, 236, 667-677.
18. Bergman RN. Toward physiological understanding of glucose tolerance. Minimal model approach. Diabetes, 1989, 38, 1512-1527.
19. Araúxo D, Camarero E, Iglesias M, Cabezas-Cerrato J. Insulin sensitivity in non-insulin-dependent diabetes mellitus and obesity using the minimal model approach. Importance of early insulin secretion on carbohydrate tolerance. In : Crepaldi G, Tiengo A, Enzy G, eds. Diabetes, obesity and hyperlipemias-lV., Elsevier Science Publisher B.V, Amsterdam, 1990, 211-213.
20. Araúxo D, Cabezas-Cerrato J. Mathematical models for the study of peripheral insulin sensitivity and beta cell function: [I] Minimal model of glucose metabolism. Av Diabetol, 1994, 8, 69-88.
21. Pacini G, Bergman RN. MINMOD : a computer program to calculate insulin sensitivity and pancreatic responsivity from the frequently sampled intravenous glucose tolerance test. Comp Meth Progr Biomed, 1986, 23,113-22.
22. Prigeon RL, Kahn SE, Porte D Jr. Reliability of error estimates from minimal model: implications for measurements in physiological studies. Am J Physiol, 1994, 266, 279-286.
23. Modan M, Halkin H, Almog S, et al. Hyperinsulinemia: a link between hypertension, obesity and glucose intolerance. J Clin Invest, 1985, 75, 809-817.
24. Ferrannini E, DeFronzo RA. Insulin resistance. In: Grill GV, Efendic S eds, Pathogenesis of non-insulin-dependent diabetes mellitus. Raven Press, New York, 1988, 201-220.
25. Natali A, Santoro D, Palombe C, Cerri M, Ghione S, Ferrannini E. Impaired insulin action on skeletal muscle metabolism in essential hypertension. Hypertension, 1991, 17, 170-178.
26. Capaldo B, Lembo G, Napoli R, et al. Skeletal muscle is a primary site of insulin resistance in esential hypertension. Metabolism, 1991, 40, 1320-1322.
27. Pollare Th, Lithell H, Berne Ch. Insulin resistance is a characteristic feature of primary hypertension independent of obesity. Metabolism, 1990, 39, 167-174.
28. Fontbonne A. Why can high insulin levels indicate a risk for coronary heart disease ? Diabetologia, 1994, 37, 953-955.
29. Lind L, Beme C, Lithell H. Prevalence of insulin resistance in essential hypertension. Hypertension, 1995, 13, 1457-62.
30. Widgren BR, Urbanavicius V, Attvall S, Person B. Insulin sensitivity is more related to fat distribution than to heredity for hypertension in normotensive men. Metabolism, 1994, 43, 883-886.
31. Welch S, Gebhart SSP, Bergman RN et al. Minimal model analysis of intravenous glucose tolerance test-derived insulin sensitivity in diabetic subjects. J Clin Endocrinol Metab, 1990, 71,1508-18.
32. Pardell, H. Blood hypertension as a problem of community in Spain, Edited by Liga Española para la Lucha contra la Hipertension Arterial. Madrid, 1986, 1-15.
33. Feinlieb M. Genetics and familial aggregation of blood pressure. In: Onesti C, Klimt CR eds, Hypertension determinants, complications and intervention. Ed. Grune & Stratton, New York, 1979, 35-48.
34. Bianchi S, Bigazzi R, Valtriani C, et al. Elevated serum insulin levels in patients with essential hypertension and microalbuminuria. Hypertension, 1994, 23 [part 1], 681-687.
35. Sharma AM, Ruland K, Spies K-P, Distler, A. Salt sensitivity in young normotensive subjects is associated with a hyperinsulinemic response to oral glucose. J. Hypertension, 1991, 9, 329-335.
36. Sharma AM, Schorr U, Distler A. Insulin resistance in young salt-sensitive normotensive subjets. Hypertension, 1993, 21, 273-279.
37. Egan BM, Stepniakowski K, Nazzaro P. Insulin levels are similar in obese salt-sensitive and salt-resistant hypertensive subjects. Hypertension, 1994, 23 (Suppl 1), I-1-7.
38. Abel ED, Ledingham JhG. Impaired glucose tolerance in hypertension is associated with impaired insulin release independently of changes in insulin sensitivity. Hypertension, 1994, 72, 1265-1273.