Dichloroacetic acid pretreatment of male and female rats increases chloroform-induced hepatotoxicity

Toxicology

Volumn 124, Issue 1, 1997, Pages 63-72

  Yang, Hui Min ^a   Davis, Mary E ^a  

^a WEST VIRGINIA UNIVERSITY   (United States)

Author keywords

Chloroform; Covalent binding; Cytochrome P450 content; Dichloroacetic acid; Glutathione content; Potentiation of hepatotoxicity

Indexed keywords

BILIRUBIN; CHLOROFORM; CYTOCHROME P450 ISOENZYME; DICHLOROACETIC ACID; GLUTATHIONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHLORINATION; CONTROLLED STUDY; COVALENT BOND; DRUG METABOLISM; DRUG POTENTIATION; FEMALE; LIVER INJURY; LIVER TOXICITY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SEX DIFFERENCE; TOXICOKINETICS;

ANIMALS; CHLOROFORM; DICHLOROACETATE; DRUG SYNERGISM; FEMALE; LIVER; MALE; RATS; RATS, SPRAGUE-DAWLEY; SEX FACTORS;

ANIMALIA;

EID: 0030731455     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-483X(97)00129-7     Document Type: Article

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