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Volumn 65, Issue 12, 1997, Pages 5110-5117

Isolation and characterization of a pigmentless-conidium mutant of Aspergillus fumigatus with altered conidial surface and reduced virulence

Author keywords

[No Author keywords available]

Indexed keywords

HYDROGEN PEROXIDE; LUMINOL; OXIDIZING AGENT; PIGMENT; REACTIVE OXYGEN METABOLITE;

EID: 0030729225     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.65.12.5110-5117.1997     Document Type: Article
Times cited : (194)

References (51)
  • 1
    • 0026497888 scopus 로고
    • Selective expression of a major allergen and cytotoxin, Asp f I, in Aspergillus fumigatus. Implications for the immunopathogenesis of Aspergillus-related diseases
    • Arruda, L. K., B. J. Mann, and M. D. Chapman. 1992. Selective expression of a major allergen and cytotoxin, Asp f I, in Aspergillus fumigatus. Implications for the immunopathogenesis of Aspergillus-related diseases. J. Immunol. 149:3354-3359.
    • (1992) J. Immunol. , vol.149 , pp. 3354-3359
    • Arruda, L.K.1    Mann, B.J.2    Chapman, M.D.3
  • 2
    • 0025185294 scopus 로고
    • Aspergillus fumigatus allergen I, a major IgE-binding protein, is a member of the mitogillin family of cytotoxins
    • Arruda, L. K., T. A. Platts Mills, J. W. Fox, and M. D. Chapman. 1990. Aspergillus fumigatus allergen I, a major IgE-binding protein, is a member of the mitogillin family of cytotoxins. J. Exp. Med. 172:1529-1532.
    • (1990) J. Exp. Med. , vol.172 , pp. 1529-1532
    • Arruda, L.K.1    Platts Mills, T.A.2    Fox, J.W.3    Chapman, M.D.4
  • 3
    • 0026794926 scopus 로고
    • Use of randomly amplified polymorphic DNA markers to distinguish isolates of Aspergillus fumigatus
    • Aufauvre-Brown, A., J. Cohen, and D. W. Holden. 1992. Use of randomly amplified polymorphic DNA markers to distinguish isolates of Aspergillus fumigatus. J. Clin. Microbiol. 30:2991-2993.
    • (1992) J. Clin. Microbiol. , vol.30 , pp. 2991-2993
    • Aufauvre-Brown, A.1    Cohen, J.2    Holden, D.W.3
  • 4
    • 0017834531 scopus 로고
    • Oxygen-dependent microbial killing by phagocytes
    • Babior, B. M. 1978. Oxygen-dependent microbial killing by phagocytes. N. Engl. J. Med. 298:659-668.
    • (1978) N. Engl. J. Med. , vol.298 , pp. 659-668
    • Babior, B.M.1
  • 5
    • 0027183815 scopus 로고
    • A guide to the use of pore-forming toxins for controlled permeabilization of cell membranes
    • Bhakdi, S., U. Weller, I. Walev, E. Martin, D. Jonas, and M. Palmer. 1993. A guide to the use of pore-forming toxins for controlled permeabilization of cell membranes. Med. Microbiol. Immunol. 182:167-175.
    • (1993) Med. Microbiol. Immunol. , vol.182 , pp. 167-175
    • Bhakdi, S.1    Weller, U.2    Walev, I.3    Martin, E.4    Jonas, D.5    Palmer, M.6
  • 6
    • 0028021306 scopus 로고
    • Bidrectional gene transfer between Aspergillus fumigatus and Aspergillus nidulans
    • Borgia, P. T., C. L. Dodge, L. E. Eagleton, and T. H. Adams. 1994 Bidrectional gene transfer between Aspergillus fumigatus and Aspergillus nidulans. FEMS Microbiol. Lett. 122:227-232.
    • (1994) FEMS Microbiol. Lett. , vol.122 , pp. 227-232
    • Borgia, P.T.1    Dodge, C.L.2    Eagleton, L.E.3    Adams, T.H.4
  • 8
    • 0029072701 scopus 로고
    • Use of reporter genes to identify recessive trans-acting mutations specifically involved in the regulation of Aspergillus nidulans penicillin biosynthesis genes
    • Brakhage, A. A., and J. Van den Brulle. 1995. Use of reporter genes to identify recessive trans-acting mutations specifically involved in the regulation of Aspergillus nidulans penicillin biosynthesis genes. J. Bacteriol. 177: 2781-2788.
    • (1995) J. Bacteriol. , vol.177 , pp. 2781-2788
    • Brakhage, A.A.1    Van den Brulle, J.2
  • 10
    • 0028141419 scopus 로고
    • Invasive aspergillosis in immunocompromised patients
    • Denning, D. W. 1994. Invasive aspergillosis in immunocompromised patients. Curr. Opin. Infect. Dis. 7:456-462.
    • (1994) Curr. Opin. Infect. Dis. , vol.7 , pp. 456-462
    • Denning, D.W.1
  • 11
    • 0029154447 scopus 로고
    • Efficacy of D0870 compared with those of itraconazole and amphotericin B in two murine models of invasive aspergillosis
    • Denning, D. W., L. Hall, M. Jackson, and S. Mollis. 1995. Efficacy of D0870 compared with those of itraconazole and amphotericin B in two murine models of invasive aspergillosis. Antimicrob. Agents Chemother. 39:1809-1814.
    • (1995) Antimicrob. Agents Chemother. , vol.39 , pp. 1809-1814
    • Denning, D.W.1    Hall, L.2    Jackson, M.3    Mollis, S.4
  • 12
    • 84907126745 scopus 로고
    • Itraconazole treatment of murine aspergillosis
    • Graybill, J. R., and J. Ahrens. 1985. Itraconazole treatment of murine aspergillosis. Sabouraudia 23:219-223.
    • (1985) Sabouraudia , vol.23 , pp. 219-223
    • Graybill, J.R.1    Ahrens, J.2
  • 13
    • 0028094658 scopus 로고
    • Molecular genetics of Aspergillus pathogenicity
    • Holden, D. W., C. M. Tang, and J. M. Smith. 1994. Molecular genetics of Aspergillus pathogenicity. Antonie Leeuwenhoek 65:251-255.
    • (1994) Antonie Leeuwenhoek , vol.65 , pp. 251-255
    • Holden, D.W.1    Tang, C.M.2    Smith, J.M.3
  • 14
    • 0028786391 scopus 로고
    • Antioxidant function of melanin in black fungi
    • Jacobson, E. S., E. Hove, and H. S. Emery. 1995. Antioxidant function of melanin in black fungi. Infect. Immun. 63:4944-4945.
    • (1995) Infect. Immun. , vol.63 , pp. 4944-4945
    • Jacobson, E.S.1    Hove, E.2    Emery, H.S.3
  • 15
    • 0027384213 scopus 로고
    • Antioxidant function of fungal melanin
    • Jacobson, E. S., and S. B. Tinnell. 1993. Antioxidant function of fungal melanin. J. Bacteriol. 175:7102-7104.
    • (1993) J. Bacteriol. , vol.175 , pp. 7102-7104
    • Jacobson, E.S.1    Tinnell, S.B.2
  • 16
    • 0028817139 scopus 로고
    • Susceptibility testing of Candida albicans and Aspergillus species by a simple microtiter menadione-augmented 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide assay
    • Jahn, B., E. Martin, A. Stueden, and S. Bhakdi. 1995. Susceptibility testing of Candida albicans and Aspergillus species by a simple microtiter menadione-augmented 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide assay. J. Clin. Microbiol. 33:661-667.
    • (1995) J. Clin. Microbiol. , vol.33 , pp. 661-667
    • Jahn, B.1    Martin, E.2    Stueden, A.3    Bhakdi, S.4
  • 17
    • 0029940482 scopus 로고    scopus 로고
    • Colorimetric susceptibility testing for Aspergillus fumigatus: Comparison of menadione-augmented 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide and alamar blue tests
    • Jahn, B., A. Stueben, and S. Bhakdi. 1996. Colorimetric susceptibility testing for Aspergillus fumigatus: comparison of menadione-augmented 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide and alamar blue tests. J. Clin. Microbiol. 34:2039-2041.
    • (1996) J. Clin. Microbiol. , vol.34 , pp. 2039-2041
    • Jahn, B.1    Stueben, A.2    Bhakdi, S.3
  • 20
    • 0020316973 scopus 로고
    • Melanin-lacking mutants of Cryptococcus neoformans and their virulence for mice
    • Kwon Chung, K. J., I. Polacheck, and T. J. Popkin. 1982. Melanin-lacking mutants of Cryptococcus neoformans and their virulence for mice. J. Bacteriol. 150:1414-1421.
    • (1982) J. Bacteriol. , vol.150 , pp. 1414-1421
    • Kwon Chung, K.J.1    Polacheck, I.2    Popkin, T.J.3
  • 21
    • 0022635758 scopus 로고
    • Encapsulation and melanin formation as indicators of virulence in Cryptococcus neoformans
    • Kwon Chung, K. J., and J. C. Rhodes. 1986. Encapsulation and melanin formation as indicators of virulence in Cryptococcus neoformans. Infect. Immun. 51:218-223.
    • (1986) Infect. Immun. , vol.51 , pp. 218-223
    • Kwon Chung, K.J.1    Rhodes, J.C.2
  • 22
    • 0000147902 scopus 로고
    • Aspergillosis
    • K. J. Kwon-Chung and J. E. Bennett (ed.). Lea and Febiger, Philadelphia, Pa.
    • Kwon-Chung, K. J., and J. E. Bennett. 1992. Aspergillosis, p. 201-247. In K. J. Kwon-Chung and J. E. Bennett (ed.), Medical mycology. Lea and Febiger, Philadelphia, Pa.
    • (1992) Medical Mycology , pp. 201-247
    • Kwon-Chung, K.J.1    Bennett, J.E.2
  • 23
    • 0025815204 scopus 로고
    • Secretion of a potential virulence factor, a fungal ribonucleotoxin, during human aspergillosis infections
    • Lamy, B., M. Moutaouakil, J. P. Latge, and J. Davies. 1991. Secretion of a potential virulence factor, a fungal ribonucleotoxin, during human aspergillosis infections. Mol. Microbiol. 5:1811-1815.
    • (1991) Mol. Microbiol. , vol.5 , pp. 1811-1815
    • Lamy, B.1    Moutaouakil, M.2    Latge, J.P.3    Davies, J.4
  • 24
    • 0022386573 scopus 로고
    • A rapid colorimetric assay of fungal viability with the tetrazolium salt MTT
    • Levitz, S. M., and R. D. Diamond. 1985. A rapid colorimetric assay of fungal viability with the tetrazolium salt MTT. J. Infect. Dis. 152:938-945.
    • (1985) J. Infect. Dis. , vol.152 , pp. 938-945
    • Levitz, S.M.1    Diamond, R.D.2
  • 25
    • 0021845376 scopus 로고
    • Mechanisms of resistance of Aspergillus fumigatus conidia to killing by neutrophils in vitro
    • Levitz, S. M., and R. D. Diamond. 1985. Mechanisms of resistance of Aspergillus fumigatus conidia to killing by neutrophils in vitro. J. Infect. Dis. 152:33-42.
    • (1985) J. Infect. Dis. , vol.152 , pp. 33-42
    • Levitz, S.M.1    Diamond, R.D.2
  • 26
    • 0029592714 scopus 로고
    • Analysis of the regulation of the Aspergillus nidulans penicillin biosynthesis gene AAT (PENDE), which encodes acyl coenzyme A:6-aminopenicillanic acid acyltransferase
    • Litzka, O., K. Bergh, and A. A. Brakhage. 1995. Analysis of the regulation of the Aspergillus nidulans penicillin biosynthesis gene AAT (PENDE), which encodes acyl coenzyme A:6-aminopenicillanic acid acyltransferase. Mol. Gen. Genet. 249:557-569.
    • (1995) Mol. Gen. Genet. , vol.249 , pp. 557-569
    • Litzka, O.1    Bergh, K.2    Brakhage, A.A.3
  • 27
    • 0025946207 scopus 로고
    • Quantitative analysis of opsonophagocytosis and of killing of Candida albicans by human peripheral blood leukocytes by using flow cytometry
    • Martin, E., and S. Bhakdi. 1991. Quantitative analysis of opsonophagocytosis and of killing of Candida albicans by human peripheral blood leukocytes by using flow cytometry. J. Clin. Microbiol. 29:2013-2023.
    • (1991) J. Clin. Microbiol. , vol.29 , pp. 2013-2023
    • Martin, E.1    Bhakdi, S.2
  • 28
    • 0028118697 scopus 로고
    • Novel aspect of amphotericin B action: Accumulation in human monocytes potentiates killing of phagocytosed Candida albicans
    • Martin, E., A. Stuben, A. Gorz, U. Weller, and S. Bhakdi. 1994. Novel aspect of amphotericin B action: accumulation in human monocytes potentiates killing of phagocytosed Candida albicans. Antimicrob. Agents Chemother. 38:13-22.
    • (1994) Antimicrob. Agents Chemother. , vol.38 , pp. 13-22
    • Martin, E.1    Stuben, A.2    Gorz, A.3    Weller, U.4    Bhakdi, S.5
  • 30
    • 0027377215 scopus 로고
    • Isolation and characterization of a secreted metalloprotease of As- Pergillus fumigatus
    • Monod, M., S. Paris, D. Sanglard, K. Jaton Ogay, J. Bille, and J. P. Latge. 1993. Isolation and characterization of a secreted metalloprotease of As- pergillus fumigatus. Infect. Immun. 61:4099-4104.
    • (1993) Infect. Immun. , vol.61 , pp. 4099-4104
    • Monod, M.1    Paris, S.2    Sanglard, D.3    Jaton Ogay, K.4    Bille, J.5    Latge, J.P.6
  • 32
    • 0025847569 scopus 로고
    • Isolation and characterisation of an extracellular alkaline protease of Aspergillus fumigatus
    • Monod, M., G. Togni, L. Rahalison, and E. Frenk. 1991. Isolation and characterisation of an extracellular alkaline protease of Aspergillus fumigatus. J. Med. Microbiol. 35:23-28.
    • (1991) J. Med. Microbiol. , vol.35 , pp. 23-28
    • Monod, M.1    Togni, G.2    Rahalison, L.3    Frenk, E.4
  • 33
    • 0026724280 scopus 로고
    • Cloning and expression of recombinant Aspergillus fumigatus allergen I/a (rAsp f I/a) with IgE binding and type I skin test activity
    • Moser, M., R. Crameri, G. Menz, T. Schneider, T. Dudler, C. Virchow, M. Gmachl, K. Blaser, and M. Suter. 1992. Cloning and expression of recombinant Aspergillus fumigatus allergen I/a (rAsp f I/a) with IgE binding and type I skin test activity. J. Immunol. 149:454-460.
    • (1992) J. Immunol. , vol.149 , pp. 454-460
    • Moser, M.1    Crameri, R.2    Menz, G.3    Schneider, T.4    Dudler, T.5    Virchow, C.6    Gmachl, M.7    Blaser, K.8    Suter, M.9
  • 34
    • 0023772260 scopus 로고
    • Fungal infections of the immunocompromised host: Clinical and laboratory aspects
    • Musial, C. E., F. R. Cockerill, and G. D. Roberts. 1988. Fungal infections of the immunocompromised host: clinical and laboratory aspects. Clin. Microbiol. Rev. 1:349-364.
    • (1988) Clin. Microbiol. Rev. , vol.1 , pp. 349-364
    • Musial, C.E.1    Cockerill, F.R.2    Roberts, G.D.3
  • 36
    • 0022206304 scopus 로고
    • Rapid preparation of DNA from filamentous fungi
    • Raeder, U., and P. Broder. 1985. Rapid preparation of DNA from filamentous fungi. Lett. Appl. Microbiol. 1:17-20.
    • (1985) Lett. Appl. Microbiol. , vol.1 , pp. 17-20
    • Raeder, U.1    Broder, P.2
  • 37
    • 0025669926 scopus 로고
    • Purification and characterisation of an extracellular serine proteinase from Aspergillus fumigatus and its detection in tissue
    • Reichard, U., S. Buttner, H. Eiffert, F. Staib, and R. Ruchel. 1990. Purification and characterisation of an extracellular serine proteinase from Aspergillus fumigatus and its detection in tissue. J. Med. Microbiol. 33:243-251.
    • (1990) J. Med. Microbiol. , vol.33 , pp. 243-251
    • Reichard, U.1    Buttner, S.2    Eiffert, H.3    Staib, F.4    Ruchel, R.5
  • 38
    • 0029056552 scopus 로고
    • Molecular cloning and sequencing of the gene encoding an extracellular aspartic proteinase from Aspergillus fumigatus
    • Reichard, U., M. Monod, and R. Ruchel. 1995. Molecular cloning and sequencing of the gene encoding an extracellular aspartic proteinase from Aspergillus fumigatus. FEMS Microbiol. Lett. 130:69-74.
    • (1995) FEMS Microbiol. Lett. , vol.130 , pp. 69-74
    • Reichard, U.1    Monod, M.2    Ruchel, R.3
  • 39
    • 0027981993 scopus 로고
    • Antifungal activity of elutriated human monocytes against Aspergillus fumigatus hyphae: Enhancement by granulocyte-macrophage colony-stimulating factor and interferon-gamma
    • Roilides, E., A. Holmes, C. Blake, D. Venzon, P. A. Pizzo, and T. J. Walsh. 1994. Antifungal activity of elutriated human monocytes against Aspergillus fumigatus hyphae: Enhancement by granulocyte-macrophage colony-stimulating factor and interferon-gamma. J. Infect. Dis. 170:894-899.
    • (1994) J. Infect. Dis. , vol.170 , pp. 894-899
    • Roilides, E.1    Holmes, A.2    Blake, C.3    Venzon, D.4    Pizzo, P.A.5    Walsh, T.J.6
  • 40
    • 0027380224 scopus 로고
    • Prevention of corticosteroid-induced suppression of human polymorphonuclear leukocyte-induced damage of Aspergillus fumigatus hyphae by granulocyte colony-stimulating factor and gamma interferon
    • Roilides, E., K. Uhlig, D. Venzon, P. A. Pizzo, and T. J. Walsh. 1993. Prevention of corticosteroid-induced suppression of human polymorphonuclear leukocyte-induced damage of Aspergillus fumigatus hyphae by granulocyte colony-stimulating factor and gamma interferon. Infect. Immun. 61: 4870-4877.
    • (1993) Infect. Immun. , vol.61 , pp. 4870-4877
    • Roilides, E.1    Uhlig, K.2    Venzon, D.3    Pizzo, P.A.4    Walsh, T.J.5
  • 41
    • 0015868609 scopus 로고
    • Nuclear and extranuclear inheritance of oligomycin resistance in Aspergillus nidulans
    • Rowlands, R. T., and G. Turner. 1973. Nuclear and extranuclear inheritance of oligomycin resistance in Aspergillus nidulans. Mol. Gen. Genet. 126:201-216.
    • (1973) Mol. Gen. Genet. , vol.126 , pp. 201-216
    • Rowlands, R.T.1    Turner, G.2
  • 42
    • 0028073624 scopus 로고
    • Virulence of Aspergillus fumigatus double mutants lacking restriction and an alkaline protease in a low-dose model of invasive pulmonary aspergillosis
    • Smith, J. M., C. M. Tang, S. Van Noorden, and D. W. Holden. 1994. Virulence of Aspergillus fumigatus double mutants lacking restriction and an alkaline protease in a low-dose model of invasive pulmonary aspergillosis. Infect. Immun. 62:5247-5254.
    • (1994) Infect. Immun. , vol.62 , pp. 5247-5254
    • Smith, J.M.1    Tang, C.M.2    Van Noorden, S.3    Holden, D.W.4
  • 44
    • 0027285494 scopus 로고
    • Interaction between Aspergillus fumigatus and basement membrane laminin: Binding and substrate degradation
    • Tronchin, G., J. P. Bouchara, G. Larcher, J. C. Lissitzky, and D. Chabasse. 1993. Interaction between Aspergillus fumigatus and basement membrane laminin: binding and substrate degradation. Biol. Cell 77:201-208.
    • (1993) Biol. Cell , vol.77 , pp. 201-208
    • Tronchin, G.1    Bouchara, J.P.2    Larcher, G.3    Lissitzky, J.C.4    Chabasse, D.5
  • 45
    • 0023173133 scopus 로고
    • Activity of orally, topically, and parenterally administered itraconazole in the treatment of superficial and deep mycoses: Animal models
    • Van Cutsem, J., F. Van Gerven, and P. A. Janssen. 1987. Activity of orally, topically, and parenterally administered itraconazole in the treatment of superficial and deep mycoses: animal models. Rev. Infect. Dis. 9(Suppl. 1): S15-S32.
    • (1987) Rev. Infect. Dis. , vol.9 , Issue.SUPPL. 1
    • Van Cutsem, J.1    Van Gerven, F.2    Janssen, P.A.3
  • 46
    • 0029131284 scopus 로고
    • Cryptococcus neoformans melanin and virulence: Mechanism of action
    • Wang, Y., P. Aisen, and A. Casadevall. 1995. Cryptococcus neoformans melanin and virulence: mechanism of action. Infect. Immun. 63:3131-3136.
    • (1995) Infect. Immun. , vol.63 , pp. 3131-3136
    • Wang, Y.1    Aisen, P.2    Casadevall, A.3
  • 47
    • 0028356443 scopus 로고
    • Susceptibility of melanized and nonmelanized Cryptococcus neoformans to nitrogen- And oxygen-derived oxidants
    • Wang, Y., and A. Casadevall. 1994. Susceptibility of melanized and nonmelanized Cryptococcus neoformans to nitrogen- and oxygen-derived oxidants. Infect. Immun. 62:3004-3007.
    • (1994) Infect. Immun. , vol.62 , pp. 3004-3007
    • Wang, Y.1    Casadevall, A.2
  • 48
    • 0023191977 scopus 로고
    • Oxidative killing of Aspergillus fumigatus proceeds by parallel myeloperoxidase-dependent and -independent pathways
    • Washburn, R. G., J. I. Gallin, and J. E. Bennett. 1987. Oxidative killing of Aspergillus fumigatus proceeds by parallel myeloperoxidase-dependent and -independent pathways. Infect. Immun. 55:2088-2092.
    • (1987) Infect. Immun. , vol.55 , pp. 2088-2092
    • Washburn, R.G.1    Gallin, J.I.2    Bennett, J.E.3
  • 49
    • 0025779163 scopus 로고
    • Protein kinase C-dependent and -independent activation of the NADPH oxidase of human neutrophils
    • Watson, F., J. Robinson, and S. W. Edwards. 1991. Protein kinase C-dependent and -independent activation of the NADPH oxidase of human neutrophils. J. Biol. Chem. 266:7432-7439.
    • (1991) J. Biol. Chem. , vol.266 , pp. 7432-7439
    • Watson, F.1    Robinson, J.2    Edwards, S.W.3
  • 50
    • 85054245320 scopus 로고
    • Opportunistic fungal infections
    • M. Miyaji (ed.). CRC Press, Boca Raton, Fla.
    • Yamaguchi, H. 1987. Opportunistic fungal infections, p. 101-158. In M. Miyaji (ed.), Animal models in medical mycology. CRC Press, Boca Raton, Fla.
    • (1987) Animal Models in Medical Mycology , pp. 101-158
    • Yamaguchi, H.1
  • 51
    • 0022642278 scopus 로고
    • Cryptococcal disease in patients with the acquired immunodeficiency syndrome. Diagnostic features and outcome of treatment
    • Zuger, A., E. Louie, R. S. Holzman, M. S. Simberkoff, and J. J. Rahal. 1986. Cryptococcal disease in patients with the acquired immunodeficiency syndrome. Diagnostic features and outcome of treatment. Ann. Intern. Med. 104:234-240.
    • (1986) Ann. Intern. Med. , vol.104 , pp. 234-240
    • Zuger, A.1    Louie, E.2    Holzman, R.S.3    Simberkoff, M.S.4    Rahal, J.J.5


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