Development of a novel CHL/IU cell line with an incorporated gpt shuttle vector for concurrent analysis of gene mutations and chromosome aberrations

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 393, Issue 3, 1997, Pages 295-306

  Yamada, Toru ^a   Odawara, Kyoko ^a   Kishida, Fumio ^a   Nakatsuka, Iwao ^a   Yoshitake, Akira ^a,b  

^a SUMITOMO CHEMICAL CO LTD   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

CHL IU cell line; gpt; Shuttle vector

Indexed keywords

PHOSPHORIBOSYLTRANSFERASE; TIOGUANINE;

ANIMAL CELL; ARTICLE; CELL LINE; CHROMOSOME ABERRATION; CONTROLLED STUDY; COSMID; DNA SEQUENCE; DRUG SCREENING; ESCHERICHIA COLI; GENE MUTATION; HAMSTER; IN VITRO STUDY; MODEL; MOLECULAR CLONING; MUTATION; MUTATION RATE; NONHUMAN; PRIORITY JOURNAL; SHUTTLE VECTOR;

ALANINE TRANSAMINASE; ANIMALS; BACTERIAL PROTEINS; CELL LINE; CHROMOSOME ABERRATIONS; CRICETINAE; CRICETULUS; DNA PRIMERS; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENETIC VECTORS; KARYOTYPING; LUNG; METHYLNITRONITROSOGUANIDINE; MUTAGENESIS; MUTAGENICITY TESTS; PENTOSYLTRANSFERASES; POINT MUTATION; PROTEINS; TRANSFECTION;

EID: 0030728597     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1383-5718(97)00114-9     Document Type: Article

References (44)

1. R.B. Dubridge, M.P. Calos, Recombinant shuttle vectors for the study of mutation in mammalian cells, Mutagenesis 3 (1988) 1-9.
2. A.R. Lehmann, C.F. Arlett, M. Gebara, S.A. Harcourt, M.R. James, J.R. Lamb, W.J. Muriel, H. Steingrimsdottir, Molecular analysis of genetic and epigenetic alterations in human cells, in: G. Jolles, A. Cordier (Eds.), New Trends in Genetic Risk Assessment, Academic Press, London, 1989, pp. 57-67.
3. M.M. Seidman, K. Dixon, A. Razzaque, R.J. Zagurski, M.L. Berman, A shuttle vector plasmid for studying carcinogen-induced point mutations in mammalian cells, Gene 38 (1985) 233-237.
4. N.R. Drinkwarter, D.K. Klinedinst, Chemically induced mutagenesis in a shuttle vector with a low-background mutant frequency, Proc. Natl. Acad. Sci. USA 83 (1986) 3402-3406.
5. J.S. Lebkowski, J.H. Miller, M.P. Calos, Determination of the DNA sequence changes induced by ethyl methanesulfonate in human cells, using a shuttle vector system, Mol. Cell. Biol. 6 (1986) 1838-1842.
6. R.B. DuBridge, P. Tang, H.C. Hsia, P.-M. Leong, J.H. Miller, M.P. Calos, Analysis of mutation in human cells by using an Epstein-Barr virus shuttle system, Mol. Cell. Biol. 7 (1987) 379-387.
7. C.R. Ashman, P. Jagadeeswaran, R.L. Davidson, Efficient recovery and sequencing of mutant genes from mammalian chromosomal DNA, Proc. Natl. Acad. Sci. USA 83 (1986) 3356-3360.
8. P.M. Glazer, S.N. Sarkar, W.C. Summers, Detection and analysis of UV-induced mutations in mammalian cell DNA using a lambda phage shuttle vector, Proc. Natl. Acad. Sci. USA 83 (1986) 1041-1044.
9. J.G. Burkhart, H.V. Malling, Mutagenesis of phiX174 am3 cs70 incorporated into the genome of mouse L-cells, Mutat. Res. 213 (1989) 125-134.
10. H. Ikehara, H. Kimura, T. Kato, Shuttle vector system for the analysis of mutational events in mammalian chromosomal DNA, Mutat. Res. 210 (1989) 237-247.
11. D.L. Wyborski, S. Malkhosyan, J. Moores, M. Perucho, J.M. Short, Development of a rat cell line containing stably integrated copies of lambda/ lad shuttle vector, Mutat. Res. 334 (1995) 161-165.
12. K.K. Richardson, J. Fostel, T.R. Skopek, Nucleotide sequence of the xanthine guanine phosphoribosyl transferase gene of E. coli, Nucleic Acids Res. 11 (1983) 8809-8816.
13. J. Collins, B. Hohn, Cosmids: A type of plasmid gene-cloning vector that is packageable in vitro in bacteriophage heads, Proc. Natl. Acad. Sci. USA 75 (1978) 4242-4246.
14. H. Koyama, T. Utakoji, T. Ono, A new cell line derived from new born Chinese hamster lung tissue, Gann 61 (1970) 161-167.
15. J.H. Miller, 2-Aminopurine and nitrous acid mutagenesis, in: Experiment in Molecular Genetics, Cold Spring Harbor Laboratory, New York, 1972, pp. 135-139.
16. D.T. Keough, L.A. McConachie, R.B. Gordon, J. de Jersey, B.T. Emmerson, Human hypoxanthine-guanine phosphoribosyltransferase. Development of a spectrophotometric assay and its use in detection and characterization of mutant forms, Clin. Chim. Acta 163 (1987) 301-308.
17. I. Saito, G.R. Stark, Charomids: Cosmid vectors for efficient cloning and mapping of large or small restriction fragments, Proc. Natl. Acad. Sci. USA 83 (1986) 8664-8668.
18. J. Sambrook, F.R. Fritsch, T. Maniatis, Isolation high-molecular-weight DNA from mammalian cells, in: Molecular Cloning: A Laboratory Manual, 2nd ed., Cold Spring Harbor Laboratory, New York, 1989, pp. 9.14-9.23.
19. M.A. Kastenbaum, K.O. Bowman, Tables for determining the statistical significance of mutation frequencies, Mutat. Res. 9 (1970) 527-549.
20. J. Sambrook, F.R. Fritsch, T. Maniatis, Small-scale preparations of plasmid DNA, in: Molecular Cloning: A Laboratory Manual, 2nd ed., Cold Spring Harbor Laboratory, New York, 1989, pp. 1.25-1.28.
21. H. Sockett, S. Romac, F. Hutchinson, Mutagenic specificity of N-methyl-N′-nitro-N-nitrosoguanidine in the gpt gene on a chromosome of Chinese hamster ovary cells and of Escherichia coli cells, Mol. Gen. Genet. 227 (1991) 252-259.
22. + and uvrA cells, Mol. Gen. Genet. 230 (1991) 295-301.
23. C.R. Ashman, R.L. Davidson, Sequence analysis of spontaneous mutations in a shuttle vector gene integrated into mammalian chromosomal DNA, Proc. Natl. Acad. Sci. USA 84 (1987) 3354-3358.
24. K.K. Richardson, F.C. Richardson, R.M. Crosby, J.A. Swenberg, T.R. Skopek, DNA base changes and alkylation following in vivo exposure of Escherichia coli to N-methyl-N-nitrosourea or N-ethyl-N-nitrosourea, Proc. Natl. Acad. Sci. USA 84 (1987) 344-348.
25. Y.-F. Lau, Y.W. Kan, Versatile cosmid vectors for the isolation, expression and rescue of gene sequences: Studies with the human α-globin gene cluster, Proc. Natl. Acad. Sci. USA 80 (1983) 5225-5229.
26. Y.-F. Lau, Y.W. Kan, Direct isolation of the functional human thymidine kinase gene with a cosmid shuttle vector, Proc. Natl. Acad. Sci. USA 81 (1984) 414-418.
27. 1, Mutat. Res. 265 (1992) 23-29.
28. C.B. Klein, T.G. Rossman, Transgenic Chinese hamster cell lines which exhibit variable levels of gpt mutagenesis, Environ. Mol. Mutagen. 16 (1990) 1-12.
29. C.R. Ashman, R.L. Davidson, High spontaneous mutation frequency in shuttle vector sequences recovered from mammalian cellular DNA, Mol. Cell. Biol. 4 (1984) 2266-2272.
30. K.R. Tindall, L.F. Stankowski Jr., R. Machanoff, A.W. Hsie, Analyses of mutation in pSV2 gpt-transform CHO cells, Mutat. Res. 160 (1986) 121-131.
31. L.F. Stankowski Jr., K.R. Tindall, A.W. Hsie, Quantitative and molecular analyses of ethyl metahnesulfonate- and ICR191-induced mutation in AS52 cells, Mutat. Res. 160 (1986) 133-147.
32. K.R. Tindall, L.F. Stankowski Jr., Molecular analysis of spontaneous mutation at the gpt locus in Chinese hamster ovary (AS52) cells, Mutat. Res. 220 (1989) 241-253.
33. J.P. O'Neill, P.A. Brimer, R. Machanoff, G.P. Hirsch, A.W. Hsie, A quantitative assay of mutation induction at the hypoxanthine-guanine phosphoribosyl transferase locus in Chinese hamster ovary cells (CHO/HGPRT system): Development and definition of the system, Mutat. Res. 45 (1977) 91-101.
34. A.R. Peterson, H. Peterson, C. Heidelberger, Oncogenesis, mutagenesis, DNA damage, and cytotoxicity in cultured mammalian cells treated with alkylating agents, Cancer Res. 39 (1979) 131-138.
35. M. Ishidate, Jr. (Ed.), Data Book of Chromosomal Aberration Test In Vitro, Revised ed., Life-Science Information Center/Elsevier, Tokyo/Amsterdam, 1988.
36. M. Ishidate Jr., M.C. Harnois, T. Sofuni, A comparative analysis of data on the clastogenicity of 951 chemical substances tested in mammalian cell cultures, Mutat. Res. 195 (1988) 151-213.
37. P.A. Burns, A.J.E. Gordon, B.W. Glickman, Influence of neighboring base sequence on N-methyl-N′-nitro-N-nitrosoguanidine mutagenesis in the lad gene of Escherichia coli, J. Mol. Biol. 117 (1987) 577-606.
38. 6-alkylguanine-DNA alkyltransferase on the fre-quency and spectrum of mutations induced by N-methyl-N′-nitro-N-nitrosoguanidine in the HPRT gene of diploid human fibroblasts, Mutat. Res. 250 (1991) 397-409.
39. J.-L. Yang, M.-C. Hu, C.-W. Wu, Novel mutational spectrum induced by N-methyl-N′-nitro-N-nitrosoguanidine in coding region of the hypoxanthine (guanine) phosphoribosyltransferase gene in diploid human fibroblasts, J. Mol. Biol. 221 (1991) 421-430.
40. K.R. Tindall, L.F. Stankowski Jr., R. Machanoff, A.W. Hsie, Detection of deletion mutations in pSV2 gpt-transformed cells, Mol. Cell. Biol. 4 (1984) 1411-1415.
41. A.W. Hsie, L. Recio, D.S. Katz, C.Q. Lee, M. Wagner, R.L. Schenly, Evidence for reactive oxygen species inducing mutations in mammalian cells, Proc. Natl. Acad. Sci. USA 83 (1986) 9616-9620.
42. C.S. Aaron, L.F. Stankowski Jr., Comparison of the AS52/XPRT and CHO/HPRT assays: evaluation of 6 drug candidates, Mutat. Res. 223 (1989) 121-128.
43. A.W. Hsie, Z. Xu, Y. Yu, J. An, M.L. Meltz, J.L. Schwarz, P. Hrelia, Quantitative and molecular analysis of genetic risk: A study with ionizing radiation, Environ. Mol. Mutagen. 101 (Suppl. 3) (1993) 213-218.
44. A.W. Hsie, J.R.S. Sebastian, S.W. Perdue, R.L. Schenley, M.D. Waters, Multiple-endpoint mutagenesis with Chinese hamster ovary (CHO) cells: Evaluation with eight carcinogenic and non-carcinogenic compounds, Mol. Toxicol. 1 (1987) 217-234.