Target and signal amplification: Approaches to increase the sensitivity of in situ hybridization

Histochemistry and Cell Biology

Volumn 108, Issue 4-5, 1997, Pages 325-333

  Komminoth, Paul ^a   Werner, Martin ^b  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GENE AMPLIFICATION; GENE EXPRESSION; GENE STRUCTURE; GENE TARGETING; HUMAN; HUMAN CELL; HUMAN TISSUE; IN SITU HYBRIDIZATION; PRIORITY JOURNAL; REVIEW;

FORECASTING; GENE AMPLIFICATION; HUMANS; IN SITU HYBRIDIZATION; SENSITIVITY AND SPECIFICITY;

EID: 0030728561     PISSN: 09486143     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004180050173     Document Type: Review

References (66)

1. Adams JC (1992) Biotin amplification of biotin and horseradish peroxidase signals in histochemical stains. J Histochem Cytochem 40:1457-1463
2. Bagasra O, Seshamma T, Pomerantz R (1993) Polymerase chain reaction in situ: intracellular amplification and detection of HIV-1 proviral DNA and other specific genes. J Immunol Methods 158:131-145
3. Bagasra O, Michaels FH, Zheng YM, Bobroski LE, Spitsin SV, Fu ZF, Tawadros R, Koprowski H (1995) Activation of the inducible form of nitric oxide synthase in the brains of patients with multiple sclerosis. Proc Natl Acad Sci US A 92:12041 -12045
4. Bains MA, Agarwal R, Pringle JH, Hutchinson RM, Lauder I (1993) Flow cytometric quantitation of sequence-specific mRNA in hemopoietic cell suspensions by primer-induced in situ (PRINS) fluorescent nucleotide labeling. Exp Cell Res 208:321-326
5. Bobrow MN, Harris TD, Shaughnessy KJ, Litt GJ (1989) Catalyzed reporter deposition, a novel method of signal amplification. Application to immunoussuys. J Immunol Methods 125:279-285
6. Chen B-X, Szaboles MJ, Matsushima AY, Erlanger BF (1996) A strategy for immunohistochemical signal enhancement by end-product amplification. J Histochem Cytochem 44:819-824
7. Chen RH, Fuggle SV (1993) In situ cDNA polymerase chain reaction. A novel technique for detecting mRNA expression. Am J Pathol 143:1527-1534
8. Cinti C, Santi S, Maraldi NM (1993) Localization of single copy gene by PRINS technique. Nucleic Acids Res 21:5799-5800
9. Embleton M, Gorochov G, Jones P, Winter G (1992) In-cell PCR from mRNA: amplifying and linking the rearranged immunoglobulin heavy and light chain V-genes within single cells. Nucleic Acids Res 20:3831-3837
10. Embretson J, Zupancic M, Beneke J, Till M, Wolinsky S, Ribas J, Burke A, Haase A (1993) Analysis of human immunodeficiency virus-infected tissues by amplification and in situ hybridization reveals latent and permissive infections at single-cell resolution. Proc Natl Acad Sci USA 90:357-361
11. Fahy E, Kwoh DY, Gingeras TR (1991) Self-sustained sequence replication (3SR): an isothermal transcription based amplification system alternative to PCR. Cold Spring Harbor Laboratory Press 1:25-33
12. Gosden J, Hanratty D (1993) PCR in situ: a rapid alternative to in situ hybridization for mapping short, low copy number sequences without isotopes. Biotechniques 15:78-80
13. Gosden J, Lawson D (1995) In-situ cyclic amplification of oligonucleotide primed synthesis (cycling PRINS). In: PCR application manual. Boehringer-Mannheim Corporation, Mannheim, pp 115-118
14. Haas R de, Verwoerd NP, Corput M van der, Gijlswijk R van, Siitari H, Tanke HJ (1996) The use of peroxidase-mediated deposition of biotin-tyramide in combination with time-resolved fluorescence imaging of europium chelate label in immunohistochemistry and in situ hybridization. J Histochem Cytochem 44:1091-1099
15. Haase AT, Retzel EF, Staskus KA (1990) Amplification and detection of lentiviral DNA inside cells. Proc Natl Acad Sci USA 87:4971-4975
16. Hindkjaer J, Koch J, Terkelsen C, Brandt CA, Kolvraa S, Bolund L (1994) Fast, sensitive multicolor detection of nucleic acids in situ by PRimed IN Situ labeling (PRINS). Cytogenet Cell Genet 66:152-154
17. Hindkjaer J, Hammoudah S, Clausen N, Koch J, Pedersen B (1995a) Partial triplication (7q) in a child with acute lymphoblastic leukemia demonstrated with conventional cytogenetics. PRINS, and chromosome painting. Cancer Genet Cytogenet 84:19-23
18. Hindkjaer J, Hammoudah SA, Hansen KB, Jensen PD, Koch J, Pedersen B (1995b) Translocation (1;16) identified by chromosome painting, and PRimed IN Situ-labeling (PRlNS). Report of two cases and review of the cytogenetic literature. Cancer Genet Cytogenet 79:15-20
19. Höfler H (1993) In situ polymerase chain reaction: toy or tool? (editorial). Histochemistry 99:103-104
20. Höfler H, Childers H, Montminy MR, Lechan RM, Goodmann RH, Wolfe HJ (1986) In situ hybridization methods for the detection of somatostatin mRNA in tissue sections using antisense RNA probes. Histochem J 18:597-604
21. Höfler H, Pütz B, Mueller J, Neubert W, Sutter G, Gais P (1995) In situ amplification of measles virus RNA by the self-sustained sequence replication reaction. Lab Invest 73:577-585
22. Isaacson SH, Asher DM, Godec MS, Gibbs CJ, Gajdusek DC (1996) Widespread, restricted low-level measles virus infection of brain in a case of subacute sclerosing panencephalitis. Acta Neuropathol (Berl) 91:135-139
23. Kerstens HM, Poddighe PJ, Hanselaar AG (1995) A novel in situ hybridization signal amplification method based on the deposition of biotinylated tyramine. J Histochem Cytochem 43:347-352
24. Koch J, Hindkjaer J, Mogensen J, Kolvraa S, Bolund L (1991) An improved method for chromosome-specific labeling of alpha satellite DNA in situ by using denatured double-stranded DNA probes as primers in a primed in situ labeling (PRINS) procedure. Genet Anal Tech Appl 8:171-178
25. Koch J, Mogensen J, Pedersen S, Fischer H, Hindkjaer J, Kolvraa S, Bolund L (1992) Fast one-step procedure for the detection of nucleic acids in situ by primer-induced sequence-specific labeling with fluorescein-12-dUTP. Cytogenet Cell Genet 60:1-3
26. Komminoth P (1992) Digoxigenin as an alternative probe labeling for in situ hybridization. Diagn Mol Pathol 1:142-150
27. Komminoth P (1996) Detection of mRNA in tissue sections using digoxigenin-labeled RNA and oligonucleotide probes. In: Nonradioactive in situ hybridization application manual. Boehringer Mannheim Corporation, Mannheim, pp 126-135
28. Komminoth P, Long AA (1993) In situ polymerase chain reaction. An overview of methods, applications and limitations of a new molecular technique. Virchows Arch 64:67-73
29. Komminoth P, Long AA (1994) Questioning in situ PCR. Detection of epidermal growth factor receptor mRNA in tissue sections from biopsy specimens using in situ polymerase chain reaction (letter). Am J Pathol 145:742
30. Komminoth P, Long AA (1995) In situ polymerase chain reaction - methodology, applications and non-specific pathways. In: PCR application manual. Boehringer Mannheim Corporation, Mannheim, pp 97-106
31. Komminoth P, Long AA, Ray R, Wolfe HJ (1992a) In situ polymerase chain reaction detection of viral DNA, single copy genes and gene rearrangements in cell suspensions and cytospins. Diagn Mol Pathol 1:85-97
32. 35S- and digoxigenin-labeled RNA and oligonucleotide probes for in situ hybridization. Expression of mRNA of the seminal vesicle secretion protein II and androgen receptor genes in the rat prostate. Histochemistry 98:217-228
33. Komminoth P, Adams V, Long AA, Roth J, Saremaslani P, Flury R, Schmid M, Heitz, PU (1994) Evaluation of methods for hepatitis C virus (HCV) detection in liver biopsies: comparison of histology, immunohistochemistry, in situ hybridization, reverse transcriptase (RT) PCR and in situ RT PCR. Pathol Res Pract 190:1017-1025
34. Levin MC, Fox RJ, Lehky T, Walter M, Fox CH, Flerlage N, Barnford R, Jacobson S (1996) PCR-in situ hybridization detection of human T-cell lymphotropic virus type 1 (HTLV-1) tax proviral DNA in peripheral blood lymphocytes of patients with HTLV-1-associated neurologic disease. J Virol 70:924-933
35. Long AA, Komminoth P (1996) In situ polymerase chain reaction: an overview. In: JR Gosden (ed) Methods in molecular biology, vol XX. Protocols for PRINS and in situ PCR, Humana Press, Totowa, pp 141-161
36. Long AA, Komminoth P, Wolfe HJ (1992) Detection of HIV provirus by in situ polymerase chain reaction (letter). N Engl J Med 327:1529
37. Long AA, Komminoth P, Lee E, Wolfe HJ (1993) Comparison of indirect and direct in situ polymerase chain reaction in cell preparations and tissue sections. Detection of viral DNA, gene rearrangements and chromosomal translocations. Histochemistry 99:151-162
38. Makowski GS, Aslanzadeh J, Hopfer SM (1995) In situ PCR amplification of Guthrie card DNA to detect cystic fibrosis mutations (letter). Clin Chem 41:477-479
39. Martinex, A, Miller MJ, Quinn K, Unsworth EJ, Ebina M, Cuttitta F (1995) Non-radioactive localization of nucleic acids by direct in situ PCR and in situ RT-PCR in paraffin-embedded sections. J Histochem Cytochem 43:739-747
40. Merz H, Malisius R, Mannweiler S, Zhou R, Hartmann W, Orscheschek K, Moubayed P, Feller AC (1995) ImmunoMax. A maximized immunohistochemical method for the retrieval and enhancement of hidden antigens. Lab Invest 73:149-156
41. Miller MJ, Martinez A, Unsworth EJ, Thiele CJ, Moody TW, Elsasser T, Cuttitta F (1996) Adrenoniedullin expression in human tumor cell lines. Its potential role as an autocrine growth factor. J Biol Chem 271:23345-23351
42. Mogensen J, Kolvraa S, Hindkjaer J, Petersen S, Koch J, Nygaard M, Jensen T, Gregersen N, Junker S, Bolund L (1991) Non-radioactive sequence specific detection of RNA in situ by primed in situ labelling (PRINS). Exp Cell Res 196:92-98
43. Muratori L, Gibellini D, Lenzi M, Cataleta M, Muratori P, Morelli MC, Bianchi FB (1996) Quantification of hepatitis C virus-infected peripheral blood mononuclear cells by in situ reverse transcriptase-polymerase chain reaction. Blood 88: 2768-2774
44. Murray G (1993) In situ PCR (editorial). J Pathol 169:187-188
45. Nuovo G (1992) PCR in situ hybridization. Raven Press, New York
46. Nuovo G, MacConnell P, Forde A, Delvenne P (1991) Detection of human papillomavirus DNA in formalin-fixed tissues by in situ hybridization after amplification by polymerase chain reaction. Am J Pathol 139:847-854
47. Patterson B, Till M, Otto P, Goolsby C, Furtado M, McBride L, Wolinsky S (1993) Detection of HIV-1 DNA and messenger RNA in individual cells by PCR-driven in situ hybridization and flow cytometry. Science 260:976-979
48. Pellestor F, Girardet A, Lefort G, Andreo B, Charlieu JP (1995) Rapid in situ detection of chromosome 21 by PRINS technique. Am J Med Genet 56:393-397
49. Pellestor F, Girardet A, Coignet L, Andreo B, Charlieu JP (1996) Assessment of aneuploidy for chromosomes 8, 9, 13, 16, and 21 in human sperm by using primed in situ labeling technique. Am J Hum Genet 58:797-802
50. Raap AK, Corput MPC van de, Vervenne RAW, Gijlswijk RPM van, Tanke HJ, Wiegant J (1995) Ultra-sensitive FISH using peroxidase-mediated deposition of biotin- or fluorochrome tyramides. Hum Mol Genet 4:529-534
51. Ray R, Komminoth P, Machado M, Wolfe HJ (1991) Combined polymerase chain reaction and in situ hybridization for the detection of single copy genes and viral genomic sequences in intact cells. Mod Pathol 4:124A
52. Sällström JF, Zehbe I, Alemi M, Wilander E (1993) Pitfalls of in situ polymerase chain reaction (PCR) using direct incorporation of labelled nucleotides. Anticancer Res 13:1153
53. Sällström JF, Alemi M, Spets H, Zehbe I (1994) Nonspecific amplification in in situ PCR by direct incorporation of reporter molecules. Cell Vision 1:243-251
54. Spann W, Pachmann K, Zabnienska H, Pielmeier A, Emmerich B (1991) In situ amplification of single copy gene segments in individual cells by the polymerase chain reaction. Infection 19:242-244
55. Speel EJ, Lawson D, Hopman AH, Gosden J (1995) Multi-PRINS: multiple sequential oligonucleotide primed in situ DNA synthesis reactions label specific chromosomes and produce bands. Hum Genet 95:29-33
56. Staecker H, Cammer M, Rubinstein R, VanDeWater T (1994) A procedure for RT-PCR amplification of mRNAs on histological specimens. Biotechniques 16:76-80
57. Tecott LH, Barchas JD, Eberwine JH (1988) In situ transcription: specific synthesis of complementary DNA in fixed tissue sections. Sience 240:1661-1664
58. Teo IA, Shaunak S (1995) Polymerase chain reaction in situ: an appraisal of an emerging technique. Histochem J 27:647-659
59. Terkelsen C, Koch J, Kolvraa S, Hindkjaer J, Pedersen S, Bolund L (1993) Repeated primed in situ labeling: formation and labeling of specific DNA sequences in chromosomes and nuclei. Cytogenet Cell Genet 63:235-237
60. Therkelsen AJ, Nielsen A, Koch J, Hindkjaer J, Kolvraa S (1995) Staining of human telomeres with primed in situ labeling (PRINS). Cytogenet Cell Genet 68:115-118
61. Werner M, Wasielewski R von, Komminoth P (1996) Antigen retrieval, signal amplification and intensification in immunohistochemistry. Histochem Cell Biol 105:253-260
62. Werner M, Wilkens L, Nasarek A, Tchindah J, Komminoth P (1997) Detection of karyotype changes in interphase cells: oligonucleotide primed in situ labeling (PRINS) versus fluorescence in situ hybridization. Virchows Arch 430:381-387
63. Wilkens L, Komminoth P, Nasarek A, Wasielewski R von, Werner M (1997) Rapid detection of karyotype changes in interphase bone marrow cells by oligonucleotide primed in situ labeling (PRINS). J Pathol 181:368-373
64. Zaki SR, Heneine W, Coffield LM, Greer PW, Sinha SD, Folks TM (1994) In situ polymerase chain reaction: applications and current limitations. AIDS 8:1186-1188
65. Zehbe I, Hacker GW, Sällström JF, Rylander E, Wilander E (1994a) Self-sustained sequence replication-based amplification (3SR) for the in situ detection of mRNA in cultured cells. Cell Vision 1:20-24
66. Zehbe I, Sällström JF, Hacker GW, Hauser-Kronberger C, Rylander E, Wilander E (1994b) Indirect and direct in situ PCR for the detection of human papillomavirus. An evaluation of two methods and a double staining technique. Cell Vision 1:163-167