Differing action potential shapes in rat dorsal root ganglion neurones related to their substance P and calcitonin gene-related peptide immunoreactivity

Journal of Comparative Neurology

Volumn 388, Issue 4, 1997, Pages 541-549

  McCarthy, P W ^a,b   Lawson, S N ^a,c  

^a Dept Anat Sch Med Sci U   (United Kingdom)

^b ANGLO EUROPEAN COLLEGE OF CHIROPRACTIC   (United Kingdom)

^c UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

A fibre; C fibre; Calcitonin gene related peptide; Electrophysiology; Primary afferent

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; SUBSTANCE P;

AFFERENT NERVE GROUP 1; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; NERVE CELL MEMBRANE POTENTIAL; NERVE FIBER C; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; RAT; SENSORY NERVE; SPINAL GANGLION;

ACTION POTENTIALS; ANIMALS; CALCITONIN GENE-RELATED PEPTIDE; CELL SIZE; FEMALE; GANGLIA, SPINAL; IMMUNOHISTOCHEMISTRY; LOGISTIC MODELS; NEURAL PATHWAYS; NEURONS; RATS; RATS, WISTAR; SUBSTANCE P;

EID: 0030728175     PISSN: 00219967     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9861(19971201)388:4<541::AID-CNE3>3.0.CO;2-2     Document Type: Article

References (42)

1. Duggan, A.W., I.A. Hendry, C.R. Morton, W.D. Hutchison, and Z.O. Zhao (1988) Cutaneous Stimuli releasing immunoreactive substance P in the dorsal horn of the cat. Brain Res. 451:261-273.
2. Gibson, S.J., J.M. Polak, S.R. Bloom, I.M. Sabate, P.M. Mulderry, M.A. Ghatei, G.P. McGregor, J.F.B. Morrison, J.S. Kelly, R.M. Evans, and M.G. Rosenfeld (1984) Calcitonin gene-related peptide immunoreactivity in the spinal cord of man and eight other species. J. Neurosci. 4:3101-3111.
3. Glantz, S.A. (1992) Primer of Biostatistics. New York: McGraw-Hill, Inc.
4. Görke, K., and F. Pierau (1980) Spike potentials and membrane properties of dorsal root ganglion cells in pigeons. Pflügers Arch. Eur. J. Physiol. 386:21-28.
5. Greene, E.C. (1963) Nervous System. New York: Hafner.
6. Harmar, A., and P. Keen (1986) Methods for the identification of neuropeptide processing products: Somatostatin and the kinins. Methods Enzymol. 124:335-348.
7. Harper, A.A., and S.N. Lawson (1985) Conduction velocity is related to morphological cell type in rat dorsal root ganglia. J. Physiol. (London) 359:31-46.
8. Hökfelt, T., X. Zhang, and Z. Wiesenfeld-Hallin (1994) Messenger plasticity in primary sensory neurones following axotomy and its functional implications. Trends Neurosci. 17:22-30.
9. Koerber, H.R., R.E. Druzinsky, and L.M. Mendell (1988) Properties of somata of spinal dorsal root ganglion cells differ according to peripheral receptor innervated. J. Neurophysiol. 60:1584-1596.
10. Kostyuk, P.G., N.S. Veselovsky, and A.Y. Tsyndrenko (1981) Ionic currents in the somatic membrane of rat dorsal root ganglion neurones: i. Sodium currents. Neuroscience 6:2423-2430.
11. Kuraishi, Y., N. Hiroto, Y. Sato, Y. Hino, M. Satoh, and H. Takagi (1985) Evidence that substance P and somatostatin transmit separate information related to pain in the spinal dorsal horn. Brain Res. 325:294-298.
12. Kuwayama, Y., G. Terenghi, M.J. Polak, Q.J. Trojanowski, and R.A. Stone (1987) A quantitative correlation of substance P-, Calcitonin gene-related peptide- and cholecystokinin-like immunoreactivity with retrogradely labeled trigeminal ganglion cells innervating the eye. Brain Res. 405:220-226.
13. Lawson, S.N. (1992) Morphological and biochemical cell types of sensory neurones. In S.A. Scott (ed): Sensory Neurones: Diversity, Development and Plasticity. New York: Oxford University Press, pp. 27-59.
14. Lawson, S.N., and P.J. Waddell (1991) Soma neurofilament immunoreactivity is related to cell size and fibre conduction velocity in rat primary sensory neurons. J. Physiol. (London) 435:41-63.
15. Lawson, S.N., B.A. Crepps, J. Bao, B.W. Brighton, and E.R. Perl (1994) Substance P-like immunoreactivity (SP-LI) in guinea pig dorsal root ganglia (DRGs) is related to sensory receptor type in A and C fibre neurons. J. Physiol. (London) 476P:39P (abstract).
16. Lawson, S.N., B. Crepps, H. Buck, and E.R. Perl (1996a) Correlation of CGRP-like immunoreactivity (CGRP-LI) with sensory receptor properties in dorsal root ganglion (DRG) neurones in guinea pigs. J. Physiol. (London) 493:45P (abstract).
17. Lawson, S.N., P.W. McCarthy, and E. Prabhakar (1996b) Electrophysiological properties of neurones with CGRP-like imnumoreactivity in rat dorsal root ganglia. J. Comp. Neurol. 365:355-366.
18. Lawson, S. N., B. Crepps, and E. R. Peal (1997). Relationship of substance P to afferent characteristics of dorsal root ganglion neurones in guinea pig. J. Physiol. (London) in press.
19. Le Greves, P., F. Nyberg, L. Terenius, and T. Hökfelt (1985) Calcitonin gene-related peptide is a potent inhibitor of substance P degradation. Eur. J. Pharmacol. 115:309-311.
20. Matsuda, Y., S. Yoshida, and T. Yonezawa (1978) Tetrodotoxin sensitivity and Ca component of action potentials of mouse dorsal root ganglion cells cultured in vitro. Brain Res. 154:69-82.
21. McCarthy, P.W., and S.N. Lawson (1988) Differential intracellular labelling of identified neurones with two fluorescent dyes. Brain Res. Bull. 20:261-265.
22. McCarthy, P.W., and S.N. Lawson (1989) Cell type and conduction velocity of rat primary sensory neurones with substance P-like immunoreactivity. Neuroscience 28:745-753.
23. McCarthy, P.W., and S.N. Lawson (1990) Cell type and conduction velocity of rat primary sensory neurons with calcitonin gene-related peptide-like immunoreactivity. Neuroscience 34:623-632.
24. McLean, M.J., P.B. Bennett, and R.M. Thomas (1988) Subtypes of dorsal root ganglion neurons based on different inward currents as measured by whole-cell voltage clamp. Mol. Cell Biol. 80:95-107.
25. Nowycky, M.C. (1992) Voltage-gated ion channels in dorsal root ganglion neurons. In S.A. Scott (ed): Sensory Neurons: Diversity, Development and Plasticity. New York: Oxford University Press, pp. 97-115.
26. Otsuka, M., and K. Yoshioka (1993) Neurotransmitter functions of mammalian tachykinins. Physiol. Rev. 73:229-308.
27. Perl, E.R. (1992) Function of dorsal root ganglion neurons: An overview. In S.A. Scott (ed): Sensory Neurons: Diversity, Development and Plasticity. New York: Oxford University Press, pp. 3-23.
28. Ritter, A.M., and L.M. Mendell (1992) Somal membrane properties of physiologically identified sensory neurons in the rat: Effects of nerve growth factor. J. Neurophysiol. 68:2033-2041.
29. Ryu, P.D., G. Gerber, K. Murase, and M. Randic (1988) Calcitonin gene-related peptide enhances calcium current of rat dorsal root ganglion neurons and spinal excitatory synaptic transmission. Neurosci. Lett. 89:305-312.
30. + currents in neurones: types, physiological roles and modulation. Trends Neurosci. 19:150-154.
31. 2+ release. Neuron 7:257-264.
32. Schaible, H.G., P.J. Hope, C.W. Lang, and A.W. Duggan (1992) Calcitonin gene-related peptide causes intraspinal spreading of substance P released by peripheral stimulation. Eur. J. Neurosci. 4:750-757.
33. Scharfman, H.E., D.D. Kunkel, and P.A. Schwartzkroin (1989) Intracellular dyes mask immunoreactivity of hippocampal interneurons. Neurosci. Lett. 96:23-28.
34. Scroggs, R.S., and A.P. Fox (1992) Calcium current variation between acutely isolated adult rat dorsal root ganglion neurons of different size. J. Physiol. (London) 445:639-658.
35. Stefanini, M., C. De Martino, and L. Zamboni (1967) Fixation of ejaculated spermatozoa for electron microscopy. Nature 216:173-175.
36. Tiseo, P.J., M.W. Adler, and L. Liu-Chen (1990) Differential release of substance P and somatostatin in the rat spinal cord in response to noxious cold and heat; effect of dynorphin A(1-17). J. Pharmacol. Exp. Ther. 252:539-545.
37. Traub, R.J., and L.M. Mendell (1988) The Spinal Projection of Individual Identified Ad- and C-fibers. J. Neurophysiol. 59:41-55.
38. Tsien, R.W., D. Lipscombe, D.V. Madison, K.R. Bley, and A.P. Fox (1988) Multiple types of neuronal calcium channels and their selective modulation. Trends Neurosci. 11:431-438.
39. Waddell, P.J., and S.N. Lawson (1990) Electrophysiological properties of subpopulations of rat dorsal root ganglion neurones in vitro. Neuroscience 36:811-822.
40. Waddell, P.J., S.N. Lawson, and P.W. McCarthy (1989) Conduction velocity changes along the processes of rat primary sensory neurons. Neuroscience 30:577-584.
41. Woolf, C.J., B. Safieh Garabedian, Q.P. Ma, P. Crilly, and J. Winters (1994) Nerve growth factor contributes to the generation of inflammatory sensory hypersensitivity. Neuroscience 62:327-331.
42. Yoshida, S., and Y. Matsuda (1979) Studies on sensory neurones of the mouse with intracellular recording and dye injection techniques. J. Neurophysiol. 42:1134-1145.