Psoriatic monocytes respond sensitively to lipopolysaccharide but with limited inflammatory cytokine production

Archives of Dermatological Research

Volumn 289, Issue 11, 1997, Pages 657-659

  Mizutani, Hitoshi ^b   Ohmoto, Yasukazu ^a   Tanaka, Hideyuki ^b   Shimizu, Masayuki ^b  

^a Otsuka Cellular Technology Institute   (Japan)

^b MIE UNIVERSITY   (Japan)

Author keywords

Endotoxin; Exacerbation; IL 1; IL 6; TNF

Indexed keywords

CYTOKINE; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; CELL CULTURE; CELL SECRETION; CLINICAL ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; HUMAN CELL; MALE; MONOCYTE; PRIORITY JOURNAL; PSORIASIS;

CYTOKINES; FEMALE; HUMANS; LIPOPOLYSACCHARIDES; MALE; MIDDLE AGED; MONOCYTES; PSORIASIS;

EID: 0030728095     PISSN: 03403696     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004030050256     Document Type: Article

References (10)

1. Telfer NR, Chalmers RJ, Whale K, Colman G (1992) The role of streptococcal infection in the initiation of guttate psoriasis. Arch Dermatol 128:39-42
2. Nomura K, Mizutani H, Inachi S, Shimizu M (1995) Remission of pustular psoriasis after cholecystectomy: role of focal infection in pustularization of psoriasis. J Dermatol 22:122-124
3. Neuner P, Urbanski A, Trautinger F, Moller A, Kirnbauer R, Kapp A, Schopf E, Schwarz T, Luger TA (1991) Increased IL-6 production by monocytes and keratinocytes in patients with psoriasis. J Invest Dermatol 97:27-33
4. Mizutani H, Ohmoto Y, Mizutani T, Murata M, Shimizu M (1997) Role of increased production of monocytes TNF-α, IL-1β and IL-6 in psoriasis: relation to focal infection, disease activity and responses to treatments. J Dermatol Sci 14:145-153
5. Teranishi Y, Mizutani H, Murata M, Shimizu M, Matsushima K (1995) Increased spontaneous production of IL-8 in peripheral blood monocytes from the psoriatic patient: relation to focal infection and response to treatments. J Dermatol Sci 10:8-15
6. Gomi T, Shiohara T, Munakata T, Imanishi K, Nagashima M Interleukin 1 alpha, tumor necrosis factor alpha, and interferon gamma in psoriasis. Arch Dermatol 127:827-830
7. Higgins GC, Foster JL, Postlethwaite AE (1994) Interleukin 1 beta propeptide is detected intracellularly and extracellularly when human monocytes are stimulated with LPS in vitro. J Exp Med 180:607-614
8. Pigatto PD, Pigatto LB, Bigardi A, Altomare G, Finzi AF (1990) Factors secreted by untreated psoriatic monocytes enhance neutrophil functions. J Invest Dermatol 94:372-376
9. Oxholm A, Oxholm P, Staberg B, Bendtzen K (1989) Expression of interleukin-6-like molecules and tumor necrosis factor after topical treatment of psoriasis with a new vitamin D analog (MC 903). Acta Derm Venereol (Stockl) 69:385-390
10. Schotanus K, Tilders FJ, Berkenbosch F (1993) Human recombinant interleukin-1 receptor antagonist prevents adrenocorticotropin, but not interleukin-6 responses to bacterial endotoxin in rats. Endocrinology 133:2461-2468