Glutamate metabotropic receptor agonist 1S,3 R-ACPD induces internucleosomal DNA fragmentation and cell death in rat striatum

Brain Research

Volumn 772, Issue 1-2, 1997, Pages 45-56

  Wang, Yumei ^a   Qin, Zheng Hong ^a   Nakai, Masami ^a   Chase, Thomas N ^a  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

Author keywords

1S,3R ACPD; Apoptosis; Excitotoxicity; Kainic acid; Neurodegeneration; NMDA receptor; Quinolinic acid

Indexed keywords

1 AMINO 1,3 CYCLOPENTANEDICARBOXYLIC ACID; 2 AMINO 3 PHOSPHONOPROPIONIC ACID; CYCLOHEXIMIDE; KAINIC ACID; KAINIC ACID RECEPTOR; METABOTROPIC RECEPTOR; N METHYL DEXTRO ASPARTIC ACID; QUINOLINIC ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; DNA DAMAGE; IN SITU HYBRIDIZATION; MALE; NERVE CELL DEGENERATION; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; RAT;

ALANINE; ANIMALS; AUTORADIOGRAPHY; CELL DEATH; CYCLOLEUCINE; DNA FRAGMENTATION; ELECTROPHORESIS, AGAR GEL; EXCITATORY AMINO ACID ANTAGONISTS; HISTOCYTOCHEMISTRY; IN SITU HYBRIDIZATION; NEUROTOXINS; NUCLEOSOMES; PROTEIN SYNTHESIS INHIBITORS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, METABOTROPIC GLUTAMATE;

EID: 0030727505     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(97)00837-8     Document Type: Article

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