Management of spasticity

Current Opinion in Neurology

Volumn 10, Issue 6, 1997, Pages 498-501

  Hesse, Stefan ^a   Mauritz, Karl Heinz ^b  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b Klinik Berlin   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BOTULINUM TOXIN A; GABAPENTIN;

ARM; BLADDER DYSFUNCTION; DYSPHAGIA; ELECTROSTIMULATION; HUMAN; INTRAMUSCULAR DRUG ADMINISTRATION; LEG; MAGNETIC STIMULATION; MOTOR PERFORMANCE; MUSCLE TONE; MUSCLE WEAKNESS; QUADRIPLEGIA; SHORT SURVEY; SPASTICITY;

EID: 0030726873     PISSN: 13507540     EISSN: None     Source Type: Journal    
DOI: 10.1097/00019052-199712000-00011     Document Type: Short Survey

References (39)

1. Das TK, Park DM: Botulinum toxin in treating spasticity. Br J Clin Pharmacol 1989, 43:401-402.
2. Hesse S, Friedrich H, Domasch C, Mauritz KH: Botulinum toxin therapy for upper limb flexor spasticity: preliminary results. J Rehab Sci 1992, 5:98-101.
3. Memin B, Pollak P, Hommel M, Perret J: Treatment of spasticity with botulinum toxin. Rev Neurol (Paris) 1992, 148:212-214.
4. Konstanzer A, Ceballos-Baumann AO, Dressnandt J, Conrad B:. Botulinum toxin A treatment in spasticity of arm and leg. Nervenarzt 1993, 64:517-523.
5. Skeil DA, Barnes MP:The local treatment of spasticity. Clin Rehabit 1994, 8:240-46.
6. Dunne JW, Heye N, Dunne SL: Treatment of chronic limb spasticity with botulinum toxin A. J Neurol Neurosurg Psychiatry 1995, 58:232-235.
7. Grazko MA, Polo KB, Bhaman J. Botulinum toxin for spasticity, muscle spasms and rigidity. Neurology 1995, 45:712-717.
8. Bhakta BB, Cozens JA, Bamford JM, Chamberlain MA: Use of botulinum toxin in stroke patients with severe upper limb spasticity. J Neurol Neurosurg Psychiatry 1996, 61:30-35.
9. Simpson DM, Alexander DN, O'Brien CF, Tagliati M, Aswad AS, Leon JM, Gibson J, Mordaunt JM, Monaghan EP: Botulinum toxin type A in the treatment of upper extremity spasticity: a randomized, double-blind, placebo-controlled trial. Neurology 1996, 46:1306-1310. This is the first randomized, placebo-controlled study on the BtxA treatment of upper limb flexor spasticity in stroke patients. A total dose of 300 units of the US product was effective with respect to muscle tone reduction.
10. Yablon SA, Benjamin TA, Ivanhoe CB, Boake C: Botulinum toxin in severe upper extremity spasticity among patients with traumatic brain injury: an open-labeled trial. Neurology 1996, 47:939-944.
11. Pierson SH, Katz DI, Tarsy D: Botulinum toxin A in the treatment of spasticity: functional implications and patient selection. Arch Phys Med Rehabil 1996, 77:717-721.
12. Reiter F, Danni M, Ceravolo MG, Provinciali L: Disability changes after treatment of upper limb spasticity with botulinum toxin. J Neurol Rehab 1996, 10:47-52.
13. Dengler R, Neyer U, Wolfath K, Bettig U, Janzik HH: Local botulinum toxin in the treatment of spastic drop foot. J Neurol 1992, 239:375-378.
14. Hesse S, Luecke D, Malezic M, Bertelt C, Freidrich H, Gregoric M, Mauritz KH: Botulinum toxin treatment for lower limb extensor spasticity in chronic hemiparetic patients. J Neurol Neurosurg Psychiatry 1994, 57:1321-1324.
15. Burbaud P, Wiart L, Dubos JL, Gaujard E, Debeillex X, Joseph PA, Mazaux JM, Bioulac B, Barat M, Lagueny A: A randomised, double blind, placebo controlled trail of botulinum toxin in the treatment of spastic foot in hemiparetic patients. J Neurol Neurosurg Psychiatry 1996, 61:265-269. This is the first randomized, placebo-controlled study on the BtxA treatment of upper limb flexor spasticity in stroke patients. A total dose of 1000 units of the UK product was effective with respect to ankle muscle tone reduction and active ankle dorsiflexion.
16. Artieda J, Quesada P, Obeso JA: Reciprocal la inhibition in spastic hemiplegia. Neurology 1991, 41:286-289.
17. Rosales RL, Arimura K, Takenaga S, Osame M: Extrafusal and intrafusal muscle effects in experimental botulinum toxin-A injection. Muscle Nerve 1996, 19:488-496. This important study showed that BtxA not only affects extrafusal, but also intrafusal muscle fibre, altering the la afferent discharge.
18. Moreno-Lopez B, Pastor AM, de la Cruz RR, Delgado-Garcia JM: Dose-dependent, central effects of botulinum neurotoxin type A: a pilot study in the alert behaving cat. Neurology 1997, 48:456-464. A study showing that BtxA does not affect the innervating motor neurons is reported.
19. Hesse S, Krajnik J, Luecke D, Jahnke MT, Gregoric M, Mauritz KH: Ankle muscle activity before and after botulinum toxin therapy for lower limb extensor spasticity in chronic hemiparetic patients. Stroke 1996, 27:455-460. A study applying kinesiological EMG in the treatment of adult spastic drop foot showing that the toxin preferentially diminishes the premature activity of the plantarflexors.
20. Wilson DJ, Childers MK, Cooke DL, Smith BK: Kinamatic changes following botulinum toxin injection after traumatic brain injury. Brain Injury 1997, 11:157-167.
21. Dressler D, Argyrakis A, Schoenle PW, Wochnik G, Rüther E: Botulinum toxin therapy in rehabilitative neurology. Nervenarzt 1996, 67:686-694
22. Cormwell SJ, Raquette VL: The effect of botulinum toxin A on the function of a person with poststroke quadriplegia. Phys Ther 1996, 76:395-402.
23. Snow BJ, Tsui JKC, Bhatt MH, Varelas M, Hashimoto SA, Calne DB: Treatment of spasticity with botulinum toxin: a double blind study. Ann Neurol 1990, 28:512-515.
24. Koman LA, Mooney JF, Smith BP, Goodman A, Mulvaney T: Mangement of spasticity in cerebral palsy with botulinum-A toxin: report of a preliminary, randomized, double-blind trial. J Pediatric Orthopaedics 1994, 14:299-303.
25. Cosgrove AP: Botulinum toxin in the mangement of cerebral palsy. Eur J Neurol 1995, 2:73-80.
26. Heinen F, Korinthenberg R, Stücker R, Deuschl G: Dystonic posture of lower extremities associated with myetomeningocele: successful treatment with botulinum A toxin in a six-month old child. Neuropediatrics 1995, 26:214-216.
27. Sutherland DH, Kaufman KR, Wyatt MP, Chambers HG: Injection of botulinum A toxin into the gastrocnemius muscle of patients with cerebral palsy: a 3-dimensional motion analysis study. Gait Posture 1996, 4:269-279. A comprehensive gait analysis in children before and after BtxA treatment is provided.
28. Hesse S, Jahnke MT, Luecke D, Mauritz KH: Short-term electrical stimulation enhances the effectiveness of Botulinum toxin in the treatment of lower limb spasticity in hemiparetic patients. Neurosci Lett 1995, 201:37-40.
29. Hughes R, Walker BC: Influence of nerve-ending activity and of drugs on the rate of paralysis of rat diaphragm preparations by Clostridium botulinum type toxin A. J Physiol 1962, 160:221-233
30. Eleopra R, Tugnoli V, De Grandis D: The variability in the clinical effect induced by botulinum toxin type A: the role of muscle activity in humans. Movement Disord 1997, 12:89-94. This is a study on the enhancing effect of an additionally applied electrical stimulation.
31. Comella C, Buchman AS, Tanner CM, Brwon-Toms NC, Goetz CG: Botulinum toxin injection for spasmodic torticollis: increased magnitude of benefit with electromyographic assistance. Neurology 1992, 42:878-882.
32. Childers MK, Stacy DOM, Cooke DL, Stonnington HH: Comparison of two injection techniques using botulinum toxin in spastic hemiplegia. Am J Phys Med Rehabil 1996, 75:462-469. This study showed that there is no difference between injecting close to the motor point or alongside the muscle belly.
33. Sloop RR, Escutin RO, Mataus JA, Cole BA, Peterson GW: Doseresponse curve of human extensor digitorum brevis muscle function to intramuscularly injected botulinum toxin type A. Neurology 1996 46:1382-1386. This is an important study on the dose response curve between increasing toxin doses and the muscle paresis measured by M-wave amplitude.
34. Benecke R: Botulinum toxin for spasms and spasticity in the lower extremities. In Therapy with Botulinum Toxin. Edited by Jankovic J. Hallet M. New York: Marcel Dekker, Inc.: 1994:557-567.
35. Schnider P, Berger T, Schmied M, Fertl L, Auff E: Increased residual urine after botulinum-A-toxin treatment. Nervenarzt 1995, 66:465-467
36. Bakheit AMO, Ward CD, McLellas DL: Generalised botulism-like syndrome after intramuscular injections of botulinum toxin type A: a report of two cases. J Neurol Neurosurg Psychiatry 1997, 62:198 First report on a generalized tetraparesis in two patients.
37. Nielsen JF, Klemar B, Hansen HJ, Sinkjaer T: A new treatment of spasticity with repetitive magnetic stimulation in multiple sclerosis. J Neurol Neurosurg Psychiatry 1997, 62:254-255.
38. Struppler A, Jakob C, Müller-Barna P, Schmid M, Lorenzen HW, Prosiegel M, Paulig M: New method for early rehabilitation in extremities palsies of central origin by magnetic stimulation. Zeitschrift für EEG and EMG 1997, 27:34-38. This and [37*] are reports on the new treatment approach with repetitive magnetic stimulation.
39. Mueller ME, Gruenthal M, Oison WL, Oison WH: Gabapentin for the relief of upper motor neuron symptoms in multiple sclerosis. Arch Phys Med Rehabil 1997, 78:521-524.