메뉴 건너뛰기




Volumn 773, Issue 1-2, 1997, Pages 76-81

Involvement of iron in MPP+ toxicity in substantia nigra: Protection by desferrioxamine

Author keywords

1 Methyl 4 phenylpyridinium; Dopamine release; Iron chelator; Microdialysis; Rat; Substantia nigra

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; DEFEROXAMINE; IRON;

EID: 0030726721     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(97)00911-6     Document Type: Article
Times cited : (16)

References (41)
  • 2
    • 0029009518 scopus 로고
    • Involvement of free-radicals in MPP neurotoxicity against rat dopaminergic-neurons in culture
    • Akenaya Y., Takahashi M., Hatanaka H. Involvement of free-radicals in MPP neurotoxicity against rat dopaminergic-neurons in culture. Neurosci. Lett. 193:1995;53-56.
    • (1995) Neurosci. Lett. , vol.193 , pp. 53-56
    • Akenaya, Y.1    Takahashi, M.2    Hatanaka, H.3
  • 3
    • 0016652087 scopus 로고
    • Brain peroxidase and catalase in Parkinon's disease
    • Ambani L.M., Van Woert M.H., Murphy S. Brain peroxidase and catalase in Parkinon's disease. Arch. Neurol. 32:1975;S56-S68.
    • (1975) Arch. Neurol. , vol.32
    • Ambani, L.M.1    Van Woert, M.H.2    Murphy, S.3
  • 4
    • 0029988893 scopus 로고    scopus 로고
    • + toxicity in rat striatal slices - relationship between nonselective effects and free-radical production
    • + toxicity in rat striatal slices - relationship between nonselective effects and free-radical production. Neurochem. Res. 21:1996;73-78.
    • (1996) Neurochem. Res. , vol.21 , pp. 73-78
    • Ambrosio, S.1    Espino, A.2    Cutillas, B.3    Bartrons, R.4
  • 5
    • 0026040282 scopus 로고
    • Iron-melanin interaction and lipid peroxidation: Implication for Parkinson's disease
    • Ben-Shachar D., Riederer P., Youdim M.B.H. Iron-melanin interaction and lipid peroxidation: implication for Parkinson's disease. J. Neurochem. 57:1991;1609-1614.
    • (1991) J. Neurochem. , vol.57 , pp. 1609-1614
    • Ben-Shachar, D.1    Riederer, P.2    Youdim, M.B.H.3
  • 6
    • 0015882341 scopus 로고
    • The mitochondrial generation of hydrogen peroxide
    • Boveris A., Chance B. The mitochondrial generation of hydrogen peroxide. Biochem. J. 134:1973;707-716.
    • (1973) Biochem. J. , vol.134 , pp. 707-716
    • Boveris, A.1    Chance, B.2
  • 7
    • 0023220996 scopus 로고
    • Chemically induced Parkinson's disease: Intermediates in the oxidation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine to the 1-methyl-4-phenylpyridinium ion
    • Chacon J.N., Chedekel M.R., Land E.J., Truscott T.G. Chemically induced Parkinson's disease: intermediates in the oxidation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine to the 1-methyl-4-phenylpyridinium ion. Biochem. Biophys. Res. Commun. 144:1987;957-964.
    • (1987) Biochem. Biophys. Res. Commun. , vol.144 , pp. 957-964
    • Chacon, J.N.1    Chedekel, M.R.2    Land, E.J.3    Truscott, T.G.4
  • 8
    • 0021276089 scopus 로고
    • Metabolism of the neurotoxic terthiary amine, MPTP, by brain monoamine oxidase
    • Chiba K., Trevor A., Castagnoli N. Jr. Metabolism of the neurotoxic terthiary amine, MPTP, by brain monoamine oxidase. Biochem. Biophys. Res. Commun. 120:1984;574-578.
    • (1984) Biochem. Biophys. Res. Commun. , vol.120 , pp. 574-578
    • Chiba, K.1    Trevor, A.2    Castagnoli N., Jr.3
  • 9
    • 0026683140 scopus 로고
    • Enhanced hydroxyl radical generation by 2′-methyl analogue of MPTP: Suppression by clorgyline and deprenyl
    • Chiueh C.C., Huang S.J., Murphy D.L. Enhanced hydroxyl radical generation by 2′-methyl analogue of MPTP: Suppression by clorgyline and deprenyl. Synapse. 11:1992;346-348.
    • (1992) Synapse , vol.11 , pp. 346-348
    • Chiueh, C.C.1    Huang, S.J.2    Murphy, D.L.3
  • 10
    • 0026598930 scopus 로고
    • Irreversible inhibition of mitochodrial complex I by 1-methyl-4-phenylpyridinium: Evidence for free radical involvement
    • Cleeter M.W.J., Cooper J.M., Shapira A.H.V. Irreversible inhibition of mitochodrial complex I by 1-methyl-4-phenylpyridinium: Evidence for free radical involvement. J. Neurochem. 58:1992;786-789.
    • (1992) J. Neurochem. , vol.58 , pp. 786-789
    • Cleeter, M.W.J.1    Cooper, J.M.2    Shapira, A.H.V.3
  • 13
    • 0028000825 scopus 로고
    • Altered brain metabolism of iron as a cause of neurodegenerative disease?
    • Gerlach M., Ben-Shachar D., Riederer P., Youdim M.B.H. Altered brain metabolism of iron as a cause of neurodegenerative disease? J. Neurochem. 63:1994;793-807.
    • (1994) J. Neurochem. , vol.63 , pp. 793-807
    • Gerlach, M.1    Ben-Shachar, D.2    Riederer, P.3    Youdim, M.B.H.4
  • 14
    • 0021351203 scopus 로고
    • Oxigen toxicity, oxygen radicals, transition metals and disease
    • Halliwell B., Gutteridge J.M.C. Oxigen toxicity, oxygen radicals, transition metals and disease. Biochem. J. 219:1984;1-14.
    • (1984) Biochem. J. , vol.219 , pp. 1-14
    • Halliwell, B.1    Gutteridge, J.M.C.2
  • 15
    • 0024997609 scopus 로고
    • +) induces NADH dependent superoxide formation, and enhances NADH-dependent lipid peroxidation in bovine heart submitochondrial particles
    • +) induces NADH dependent superoxide formation, and enhances NADH-dependent lipid peroxidation in bovine heart submitochondrial particles. Biochem. Biophys. Res. Commun. 170:1990;1049-1055.
    • (1990) Biochem. Biophys. Res. Commun. , vol.170 , pp. 1049-1055
    • Hasegawa, E.1    Takeshige, K.2    Oishi, T.3    Murai, Y.4    Minikami, S.5
  • 17
    • 0022415447 scopus 로고
    • Glutathione peroxidase activity in Parkinson's disease brain
    • Kish S.J., Morito C., Hornykiewicz O. Glutathione peroxidase activity in Parkinson's disease brain. Neurosci. Lett. 58:1985;343-346.
    • (1985) Neurosci. Lett. , vol.58 , pp. 343-346
    • Kish, S.J.1    Morito, C.2    Hornykiewicz, O.3
  • 18
    • 0021337873 scopus 로고
    • Selective nigral toxicity after systemic administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the squirrel monkey
    • Langston J.W., Forno L.S., Rebert C.S., Irwin I. Selective nigral toxicity after systemic administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the squirrel monkey. Brain Res. 292:1984;390-394.
    • (1984) Brain Res. , vol.292 , pp. 390-394
    • Langston, J.W.1    Forno, L.S.2    Rebert, C.S.3    Irwin, I.4
  • 20
    • 0023154707 scopus 로고
    • The requirement for iron III in the initiation of lipid peroxidation by iron II and hydrogen peroxidase
    • Minotti G., Aust S.D. The requirement for iron III in the initiation of lipid peroxidation by iron II and hydrogen peroxidase. J. Biol. Chem. 262:1987;1098-1104.
    • (1987) J. Biol. Chem. , vol.262 , pp. 1098-1104
    • Minotti, G.1    Aust, S.D.2
  • 21
    • 0024413893 scopus 로고
    • + on the release of serotonin and 5-hydroxyindoleacetic acid from rat striatum in vivo
    • + on the release of serotonin and 5-hydroxyindoleacetic acid from rat striatum in vivo. Eur. J. Pharmacol. 166:1989;49-55.
    • (1989) Eur. J. Pharmacol. , vol.166 , pp. 49-55
    • Miyake, H.1    Chiueh, C.C.2
  • 22
    • 0024368622 scopus 로고
    • 6-Hydroxydopamine releases iron from ferritin and promotes ferritin-dependent lipid peroxidation
    • Monteiro H.P., Winterbourn C.C. 6-Hydroxydopamine releases iron from ferritin and promotes ferritin-dependent lipid peroxidation. Biochem. Pharmacol. 38:1989;4177-4182.
    • (1989) Biochem. Pharmacol. , vol.38 , pp. 4177-4182
    • Monteiro, H.P.1    Winterbourn, C.C.2
  • 24
    • 0020308323 scopus 로고
    • Parkinson's disease: A disorder due to nigra glutathione deficiency?
    • Perry T.L., Godin D.U., Hansen S. Parkinson's disease: a disorder due to nigra glutathione deficiency? Neurosci. Lett. 33:1982;305-310.
    • (1982) Neurosci. Lett. , vol.33 , pp. 305-310
    • Perry, T.L.1    Godin, D.U.2    Hansen, S.3
  • 25
    • 0029029016 scopus 로고
    • Hypoxia alters homeostasis and induces ferritin synthesis in oligodendrocites
    • Qi Y., Jamindar T.M., Dawson G. Hypoxia alters homeostasis and induces ferritin synthesis in oligodendrocites. J. Neurochem. 64:1995;2458-2464.
    • (1995) J. Neurochem. , vol.64 , pp. 2458-2464
    • Qi, Y.1    Jamindar, T.M.2    Dawson, G.3
  • 26
    • 0022496317 scopus 로고
    • Monoamine oxidase activity and monoamine metabolism in brains of parkinsonian patients treated with l-deprenyl
    • Riederer P., Youdim M.B.H. Monoamine oxidase activity and monoamine metabolism in brains of parkinsonian patients treated with l-deprenyl. J. Neurochem. 46:1986;1359-1365.
    • (1986) J. Neurochem. , vol.46 , pp. 1359-1365
    • Riederer, P.1    Youdim, M.B.H.2
  • 29
    • 0023895945 scopus 로고
    • The use of in vivo dialysis of dopamine, acetylcholine, aminoacids and lactic acid in studies on the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)
    • Rollema H., De Vries J.B., Damsma G., Westerink B.H.C., Kranenborg G.L., Kuhr W.G., Horn A.S. The use of in vivo dialysis of dopamine, acetylcholine, aminoacids and lactic acid in studies on the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Toxicology. 49:1988;503-511.
    • (1988) Toxicology , vol.49 , pp. 503-511
    • Rollema, H.1    De Vries, J.B.2    Damsma, G.3    Westerink, B.H.C.4    Kranenborg, G.L.5    Kuhr, W.G.6    Horn, A.S.7
  • 32
    • 0026060876 scopus 로고
    • + on nigral and bilateral striatal release of dopamine simultaneously recorded by microdialysis
    • + on nigral and bilateral striatal release of dopamine simultaneously recorded by microdialysis. Brain Res. 538:1991;226-230.
    • (1991) Brain Res. , vol.538 , pp. 226-230
    • Santiago, M.1    Rollema, H.2    De Vries, J.B.3    Westerink, B.H.C.4
  • 33
    • 0025152991 scopus 로고
    • Characterization of the in vivo release of dopamine as recorded by different types of intracerebral microdialysis probes
    • Santiago M., Westerink B.H.C. Characterization of the in vivo release of dopamine as recorded by different types of intracerebral microdialysis probes. Naunyn-Schmiedeberg's Arch. Pharmacol. 342:1990;407-414.
    • (1990) Naunyn-Schmiedeberg's Arch. Pharmacol. , vol.342 , pp. 407-414
    • Santiago, M.1    Westerink, B.H.C.2
  • 34
    • 0025980949 scopus 로고
    • Responsiveness of striatal dopamine release in awake animals after chronic 1-methyl-4-phenylpyridinium ion-induced lesions of the substantia nigra
    • Santiago M., Westerink B.H.C., Rollema H. Responsiveness of striatal dopamine release in awake animals after chronic 1-methyl-4-phenylpyridinium ion-induced lesions of the substantia nigra. J. Neurochem. 56:1991;1336-1342.
    • (1991) J. Neurochem. , vol.56 , pp. 1336-1342
    • Santiago, M.1    Westerink, B.H.C.2    Rollema, H.3
  • 38
    • 0028798434 scopus 로고
    • Oxidative mechanisms in the toxicity of metal ions
    • Stohns, Bagchi Oxidative mechanisms in the toxicity of metal ions. Free Radic. Biol. Med. 18:1995;321-336.
    • (1995) Free Radic. Biol. Med. , vol.18 , pp. 321-336
    • Stohns1    Bagchi2
  • 39
    • 0023499635 scopus 로고
    • Scope and limitations of in vivo brain dialysis: A comparison of its applications to various neurotransmitter systems
    • Westerink B.H.C., Damsma G., Rollema H., de Vries J.B., Horn A.S. Scope and limitations of in vivo brain dialysis: a comparison of its applications to various neurotransmitter systems. Life Sci. 41:1987;1763-1776.
    • (1987) Life Sci. , vol.41 , pp. 1763-1776
    • Westerink, B.H.C.1    Damsma, G.2    Rollema, H.3    De Vries, J.B.4    Horn, A.S.5
  • 40
    • 0027351360 scopus 로고
    • The neurotoxicity of iron and nitric oxide: Relevance to the etiology of Parkinson's disease
    • in: H. Narabayashi, T. Nagatsu, N. Yanagisawa, Y. Mizuno (Eds.), Raven Press, New York
    • M.B.H. Youdim, D. Ben-Shachar, G. Eshel, J.P.M. Finberg, P. Riederer, The neurotoxicity of iron and nitric oxide: relevance to the etiology of Parkinson's disease, in: H. Narabayashi, T. Nagatsu, N. Yanagisawa, Y. Mizuno (Eds.), Advances in Neurology, vol. 60, Raven Press, New York, 1993, pp. 259-266.
    • (1993) Advances in Neurology , vol.60 , pp. 259-266
    • Youdim, M.B.H.1    Ben-Shachar, D.2    Eshel, G.3    Finberg, J.P.M.4    Riederer, P.5
  • 41
    • 0010471495 scopus 로고
    • Cellular defences against damage from reactive oxygen species
    • Yu B.P. Cellular defences against damage from reactive oxygen species. Physiol. Rev. 74:1994;139-162.
    • (1994) Physiol. Rev. , vol.74 , pp. 139-162
    • Yu, B.P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.