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Volumn 26, Issue 1, 1997, Pages 11-22

The insulin gene region and susceptibility to insulin-dependent diabetes mellitus in pour races; New insights from Afro-Caribbean race-specific haplotypes

Author keywords

Afro Caribbean; IDDM2; Insulin gene; Insulin dependent diabetes mellitus; Races; VNTR

Indexed keywords

INSULIN;

EID: 0030726335     PISSN: 08916934     EISSN: None     Source Type: Journal    
DOI: 10.3109/08916939709009546     Document Type: Article
Times cited : (8)

References (33)
  • 1
    • 0029868398 scopus 로고    scopus 로고
    • Diabetes susceptibility at IDDM2 cannot be positively mapped to the VNTR locus of the insulin gene
    • Doria, A., Lee. J., Warram, J. H. and Krolewski, A. S. (1996). Diabetes susceptibility at IDDM2 cannot be positively mapped to the VNTR locus of the insulin gene. Diabetologia, 39, 594-599
    • (1996) Diabetologia , vol.39 , pp. 594-599
    • Doria, A.1    Lee, J.2    Warram, J.H.3    Krolewski, A.S.4
  • 3
    • 0021343570 scopus 로고
    • A polymorphic locus near the human insulin gene is associated with insulin-dependent diabetes mellitus
    • Bell, G. I., Horita, S. and Karam, J. H. (1984). A polymorphic locus near the human insulin gene is associated with insulin-dependent diabetes mellitus. Diabetes, 33, 176-183
    • (1984) Diabetes , vol.33 , pp. 176-183
    • Bell, G.I.1    Horita, S.2    Karam, J.H.3
  • 4
    • 0027377799 scopus 로고
    • Transmission test for linkage disequilibrium: The insulin gene region and insulin-dependent diabetes mellitus
    • Spielman, R. S., McGinnis, R. E. and Ewens, W. J. (1993). Transmission test for linkage disequilibrium: The insulin gene region and insulin-dependent diabetes mellitus. Am J Hum Genet, 52, 506-516
    • (1993) Am J Hum Genet , vol.52 , pp. 506-516
    • Spielman, R.S.1    McGinnis, R.E.2    Ewens, W.J.3
  • 5
    • 0025995836 scopus 로고
    • Insulin-IGF2 region on chromosome lip encodes a gene implicated in HLA-DR4 dependent diabetes susceptibility
    • Julier, C., Hyer, R. N., Davies, J., Merlin, F., Soularue, P. and Briant, L. et al. (1991). Insulin-IGF2 region on chromosome lip encodes a gene implicated in HLA-DR4 dependent diabetes susceptibility. Nature, 354, 155-159
    • (1991) Nature , vol.354 , pp. 155-159
    • Julier, C.1    Hyer, R.N.2    Davies, J.3    Merlin, F.4    Soularue, P.5    Briant, L.6
  • 6
    • 17644447822 scopus 로고
    • Insulin gene region-encoded susceptibility to type 1 diabetes is not restricted to HLA-DR4-positive individuals
    • Bain, S. C, Prins, J. B., Hearne, C. M., Rodrigues, N., Rowe, B. R. and Pritchard, L. E. et al. (1992). Insulin gene region-encoded susceptibility to type 1 diabetes is not restricted to HLA-DR4-positive individuals. Nature Genet, 2, 212-215
    • (1992) Nature Genet , vol.2 , pp. 212-215
    • Bain, S.C.1    Prins, J.B.2    Hearne, C.M.3    Rodrigues, N.4    Rowe, B.R.5    Pritchard, L.E.6
  • 7
    • 0028859447 scopus 로고
    • Insulin gene 5' flanking polymorphism. Length of class 1 alleles in number of repeat units
    • McGinnis, R. E. and Spielman, R. S. (1995). Insulin gene 5' flanking polymorphism. Length of class 1 alleles in number of repeat units. Diabetes, 44, 1296-1302
    • (1995) Diabetes , vol.44 , pp. 1296-1302
    • McGinnis, R.E.1    Spielman, R.S.2
  • 8
    • 0001017310 scopus 로고    scopus 로고
    • IDDM2-VNTR-encoded susceptibility to Type 1 diabetes: Dominant protection and parental transmission of alleles of the insulin gene-linked minisatellite locus
    • Bennett, S. T., Wilson, A. J., Cucca, F., Nerup, J., Pociot, F. and McKinney, P. et al. (1996) IDDM2-VNTR-encoded susceptibility to Type 1 diabetes: Dominant protection and parental transmission of alleles of the insulin gene-linked minisatellite locus. J Autoimmunity. 9, 415-421
    • (1996) J Autoimmunity , vol.9 , pp. 415-421
    • Bennett, S.T.1    Wilson, A.J.2    Cucca, F.3    Nerup, J.4    Pociot, F.5    McKinney, P.6
  • 9
    • 0028871202 scopus 로고
    • Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene microsatellite locus
    • Bennett, S. T., Lucassen, A. M., Gough, S. C. L., Powell, E. E., Undlien, D. E. and Pritchard, L. E. et al. (1995). Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene microsatellite locus. Nature Genet, 9, 284-292
    • (1995) Nature Genet , vol.9 , pp. 284-292
    • Bennett, S.T.1    Lucassen, A.M.2    Gough, S.C.L.3    Powell, E.E.4    Undlien, D.E.5    Pritchard, L.E.6
  • 10
    • 0028964371 scopus 로고
    • Regulation of insulin gene expression by the IDDM associated, insulin locus haplotype
    • Lucassen, A. M., Screaton, G. R., Julier, C., Elliot, T. J., Lathrop, M. and Bell, J. I. (1995). Regulation of insulin gene expression by the IDDM associated, insulin locus haplotype. Hum Mol Gen, 4, 501-506
    • (1995) Hum Mol Gen , vol.4 , pp. 501-506
    • Lucassen, A.M.1    Screaton, G.R.2    Julier, C.3    Elliot, T.J.4    Lathrop, M.5    Bell, J.I.6
  • 11
    • 0029987192 scopus 로고    scopus 로고
    • The search for IDDM susceptibility genes. The next generation
    • Owerbach, D. and Gabbay, K. H. (1996). The search for IDDM susceptibility genes. The next generation. Diabetes, 45, 544-551
    • (1996) Diabetes , vol.45 , pp. 544-551
    • Owerbach, D.1    Gabbay, K.H.2
  • 12
    • 0028881617 scopus 로고
    • The minisatellite in the diabetes susceptibility locus IDDM2 regulates insulin transcription
    • Kennedy, G. C., German, M. S. and Rutter, W. J. (1995). The minisatellite in the diabetes susceptibility locus IDDM2 regulates insulin transcription. Nature Genet, 9, 293-298
    • (1995) Nature Genet , vol.9 , pp. 293-298
    • Kennedy, G.C.1    German, M.S.2    Rutter, W.J.3
  • 13
    • 0027200763 scopus 로고
    • Susceptibility to insulin dependent diabetes mellitus maps to a 4.1 kb segment of DNA spanning the insulin gene and associated VNTR
    • Lucassen, A. M., Julier, C., Beressi, J. P., Boitard, C., Froguel, P. and Lathrop, M. et al. (1993). Susceptibility to insulin dependent diabetes mellitus maps to a 4.1 kb segment of DNA spanning the insulin gene and associated VNTR. Nature Genet, 4, 305-310
    • (1993) Nature Genet , vol.4 , pp. 305-310
    • Lucassen, A.M.1    Julier, C.2    Beressi, J.P.3    Boitard, C.4    Froguel, P.5    Lathrop, M.6
  • 14
    • 0027944781 scopus 로고
    • Multiple DNA variant association analysis: Application to the insulin gene in Type 1 diabetes
    • Julier, C., Lucassen, A., Villedieu, P., Delepine, M., Levy-Marchal. C. and Danzé, P. (1994). Multiple DNA variant association analysis: Application to the insulin gene in Type 1 diabetes. Am J Hum Genet, 55, 1247-1254
    • (1994) Am J Hum Genet , vol.55 , pp. 1247-1254
    • Julier, C.1    Lucassen, A.2    Villedieu, P.3    Delepine, M.4    Levy-Marchal, C.5    Danzé, P.6
  • 15
    • 0028999853 scopus 로고
    • Insulin gene region-encoded susceptibility to IDDM maps upstream of the insulin gene
    • Undlien, D. E., Bennett, S. T., Todd, J. A., Akselsen, H. E., Ikäheimo, I. and Reijonen, H. et al. (1995). Insulin gene region-encoded susceptibility to IDDM maps upstream of the insulin gene. Diabetes, 44, 620-625
    • (1995) Diabetes , vol.44 , pp. 620-625
    • Undlien, D.E.1    Bennett, S.T.2    Todd, J.A.3    Akselsen, H.E.4    Ikäheimo, I.5    Reijonen, H.6
  • 16
    • 0025375542 scopus 로고
    • Identification of susceptibility loci for Type 1 (insulin-dependent) diabetes by trans-racial gene mapping
    • Jenkins, D., Mijovic, C., Fletcher, J., Jacobs, K. H., Bradwell, A. R. and Barnett, A. H. (1990). Identification of susceptibility loci for Type 1 (insulin-dependent) diabetes by trans-racial gene mapping. Diabetologia, 33, 387-395
    • (1990) Diabetologia , vol.33 , pp. 387-395
    • Jenkins, D.1    Mijovic, C.2    Fletcher, J.3    Jacobs, K.H.4    Bradwell, A.R.5    Barnett, A.H.6
  • 17
    • 0022414832 scopus 로고
    • New polymorphisms at the insulin locus increase its usefulness as a genetic marker
    • Elbein, S. C., Corsetti, L. and Permutt, M. A. (1985). New polymorphisms at the insulin locus increase its usefulness as a genetic marker. Diabetes, 34, 1139- 1144
    • (1985) Diabetes , vol.34 , pp. 1139-1144
    • Elbein, S.C.1    Corsetti, L.2    Permutt, M.A.3
  • 18
    • 0022501681 scopus 로고
    • Evidence for increased recombination near the human insulin gene: Implication for disease association studies
    • Chakravarti, A., Elbein, S. C. and Permutt. M. A. (1986). Evidence for increased recombination near the human insulin gene: Implication for disease association studies. Proc Natl Acad Sci USA, 83, 1045-1049
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 1045-1049
    • Chakravarti, A.1    Elbein, S.C.2    Permutt, M.A.3
  • 19
    • 0026092633 scopus 로고
    • Allele-specific gene probing supports the DQ molecule as a determinant of inherited susceptibility to Type 1 (insulin-dependent) diabetes
    • Jenkins, D., Mijovic, C., Jacobs, K. H., Penny, M. A., Fletcher, J. and Barnett, A. H. (1991). Allele-specific gene probing supports the DQ molecule as a determinant of inherited susceptibility to Type 1 (insulin-dependent) diabetes. Diabetologia, 34, 109-113
    • (1991) Diabetologia , vol.34 , pp. 109-113
    • Jenkins, D.1    Mijovic, C.2    Jacobs, K.H.3    Penny, M.A.4    Fletcher, J.5    Barnett, A.H.6
  • 20
    • 0025778297 scopus 로고
    • HLA-DQA1 and HLA-DQB1 alleles are associated with genetic susceptibility to IDDM in a Negroid population
    • Mijovic, C., Jenkins, D., Jacobs, K. H., Penny, M. A., Fletcher, J. A. and Barnett, A. H. (1991). HLA-DQA1 and HLA-DQB1 alleles are associated with genetic susceptibility to IDDM in a Negroid population. Diabetes. 40, 748-753
    • (1991) Diabetes , vol.40 , pp. 748-753
    • Mijovic, C.1    Jenkins, D.2    Jacobs, K.H.3    Penny, M.A.4    Fletcher, J.A.5    Barnett, A.H.6
  • 21
    • 9844261431 scopus 로고
    • An investigation of Japanese subjects maps susceptibility to Type 1 (insulindependent) diabetes close to the DQA1 gene
    • Jacobs, K. H., Jenkins, D., Mijovic, C., Penny, M., Uchigata, Y. and Cavan, D. et al. (1992). An investigation of Japanese subjects maps susceptibility to Type 1 (insulindependent) diabetes close to the DQA1 gene. Hum Immunol, 33, 53-57
    • (1992) Hum Immunol , vol.33 , pp. 53-57
    • Jacobs, K.H.1    Jenkins, D.2    Mijovic, C.3    Penny, M.4    Uchigata, Y.5    Cavan, D.6
  • 22
    • 0026724988 scopus 로고
    • Susceptibility to IDDM in a Chinese population. Role of HLA class II alleles
    • Penny, M. A., Jenkins, D., Mijovic, C. H., Jacobs, K. H., Cavan, D. A. and Yeung, V. T. F. et al. (1992). Susceptibility to IDDM in a Chinese population. Role of HLA class II alleles. Diabetes, 41, 914-919
    • (1992) Diabetes , vol.41 , pp. 914-919
    • Penny, M.A.1    Jenkins, D.2    Mijovic, C.H.3    Jacobs, K.H.4    Cavan, D.A.5    Yeung, V.T.F.6
  • 23
    • 9844237863 scopus 로고    scopus 로고
    • A comparative study of DR/DQ alleles in Jamaican Type 1 diabetic patients in two countries
    • Abstract
    • Heward, J., Mijovic, C. H., Morrison, E. and Barnett, A. H. (1996). A comparative study of DR/DQ alleles in Jamaican Type 1 diabetic patients in two countries. Diabetologia. 295 (Abstract) 39
    • (1996) Diabetologia , vol.39 , pp. 295
    • Heward, J.1    Mijovic, C.H.2    Morrison, E.3    Barnett, A.H.4
  • 24
    • 0026682512 scopus 로고
    • A variant insulin promoter in non-insulin-dependent diabetes mellitus
    • Olansky, L., Welling, C., Giddings, S., Adler, S., Bourey, R. and Dowse, G. et al. (1992). A variant insulin promoter in non-insulin-dependent diabetes mellitus. J Clin Invest, 89, 1596-1602
    • (1992) J Clin Invest , vol.89 , pp. 1596-1602
    • Olansky, L.1    Welling, C.2    Giddings, S.3    Adler, S.4    Bourey, R.5    Dowse, G.6
  • 25
    • 0023696436 scopus 로고
    • Linkage disequilibrium in the human insulin/insulin-like growth factor II region of human chromosome 11
    • Cox, N. J., Bell, G. I. and Xiang, K. (1988). Linkage disequilibrium in the human insulin/insulin-like growth factor II region of human chromosome 11. Am J Hum Genet, 43, 495-501
    • (1988) Am J Hum Genet , vol.43 , pp. 495-501
    • Cox, N.J.1    Bell, G.I.2    Xiang, K.3
  • 26
    • 0022921742 scopus 로고
    • DNA polymorphic haplotypes on the short arm of chromosome 11 and the inheritance of type 1 diabetes mellitus
    • Ferns, G. A., Hitman, G., Trembath, B., Williams, L., Tarn, A., Gale, E. A. and Galton, D. J. (1986). DNA polymorphic haplotypes on the short arm of chromosome 11 and the inheritance of type 1 diabetes mellitus. J. Med Genet, 23, 210-216
    • (1986) J. Med Genet , vol.23 , pp. 210-216
    • Ferns, G.A.1    Hitman, G.2    Trembath, B.3    Williams, L.4    Tarn, A.5    Gale, E.A.6    Galton, D.J.7
  • 27
  • 28
    • 0002652676 scopus 로고
    • Statistical aspects of immunogenetic associations with disease
    • Simons MJ. Tait BD (eds) London: Churchill Livingstone
    • Mathews, J. D. (1984). Statistical aspects of immunogenetic associations with disease. In: Simons MJ. Tait BD (eds) Detection of immune-associated genetic markers of human disease, London: Churchill Livingstone.
    • (1984) Detection of Immune-associated Genetic Markers of Human Disease
    • Mathews, J.D.1
  • 29
    • 0008339805 scopus 로고
    • The Americas Area 5. The Caribbean Islands
    • McEvedy C, Jones R (eds), London: Penguin
    • McEvedy and Jones, R. (1978). The Americas Area 5. The Caribbean Islands. In: McEvedy C, Jones R (eds), Atlas of World Population History. London: Penguin.
    • (1978) Atlas of World Population History
    • McEvedy1    Jones, R.2
  • 30
    • 0026762723 scopus 로고
    • Variability of the insulin gene in American blacks with NIDDM. Analysis by single-strand conformational polymorphisms
    • Olansky, L., Janssen, R., Welling, C. and Permutt, M. A. (1992). Variability of the insulin gene in American blacks with NIDDM. Analysis by single-strand conformational polymorphisms. Diabetes, 41, 742-749
    • (1992) Diabetes , vol.41 , pp. 742-749
    • Olansky, L.1    Janssen, R.2    Welling, C.3    Permutt, M.A.4
  • 31
    • 0028044873 scopus 로고
    • Lack of association with the insulin gene with Type I (insulin-dependent) diabetes mellitus in Japanese subjects
    • Matsumoto, C., Awata, T., Iwamoto, Y., Kuzuya, T., Saito, Y. and Kanazawa, Y. (1994) Lack of association with the insulin gene with Type I (insulin-dependent) diabetes mellitus in Japanese subjects. Diabetologia, 37, 210-213
    • (1994) Diabetologia , vol.37 , pp. 210-213
    • Matsumoto, C.1    Awata, T.2    Iwamoto, Y.3    Kuzuya, T.4    Saito, Y.5    Kanazawa, Y.6
  • 32
    • 9844258042 scopus 로고    scopus 로고
    • Possible association of shorter class 1 alleles with IDDM in Japan: Repeat number of the 5' insulin gene VNTR
    • Abstract
    • Awata, T., Kikuchi, C., Kanazawa, Y. and Katayama, S. (1996). Possible association of shorter class 1 alleles with IDDM in Japan: Repeat number of the 5' insulin gene VNTR. Diabetes, 229 (Abstract) 45.
    • (1996) Diabetes , vol.45 , pp. 229
    • Awata, T.1    Kikuchi, C.2    Kanazawa, Y.3    Katayama, S.4
  • 33
    • 0028031222 scopus 로고
    • IDDM susceptibility associated with polymorphisms in the insulin gene region. A study of blacks, Caucasians and orientals
    • Undlien, D., Hamaguchi, K., Kimura, A. and Tuomilehto-Wolf, E., Swai, A. B. M., McLarty, D. G. et al. (1994) IDDM susceptibility associated with polymorphisms in the insulin gene region. A study of blacks, Caucasians and orientals. Diabetologia, 37, 745-749
    • (1994) Diabetologia , vol.37 , pp. 745-749
    • Undlien, D.1    Hamaguchi, K.2    Kimura, A.3    Tuomilehto-Wolf, E.4    Swai, A.B.M.5    McLarty, D.G.6


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