Tumour cell u-PA as a cause of fibrinolytic bleeding in metastatic disease

British Journal of Haematology

Volumn 99, Issue 3, 1997, Pages 570-574

  Bennett, Bruce ^a,c   Croll, Alison M ^a   Robbie, Linda A ^a   Herriot, Richard ^b  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

^b NHS GRAMPIAN   (United Kingdom)

^c UNIVERSITY OF ABERDEEN   (United Kingdom)

Author keywords

Bleeding disorder; Fibrinolysis; Metastatic disease; Tumour cell u PA

Indexed keywords

PLASMIN; THROMBIN; UROKINASE;

ADENOCARCINOMA; ADULT; ARTICLE; BLEEDING DISORDER; CASE REPORT; CLINICAL FEATURE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; METASTASIS; PRIORITY JOURNAL; THROMBIN TIME; THROMBOCYTE COUNT;

EID: 0030726242     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1997.4303242.x     Document Type: Article

References (11)

1. 2-antiplasmin and C1 inhibitor: studies on patients with defibrination and a fibrinolytic state after electroshock or complicated labor. Blood, 75, 671-676.
2. Booth, N.A., Anderson, J.A. & Bennett, B. (1984) Plasminogen activators in alcoholic cirrhosis: demonstration of increased tissue type and urokinase type activator. Journal of Clinical Pathology, 37, 772-777.
3. 2-antiplasmin complex as an indicator of in vivo fibrinolysis. British Journal of Haematology, 50, 537-541.
4. Booth, N.A., Simpson, A.J., Croll, A., Bennett, B. & MacGregor, I.R. (1988) Plasminogen activator inhibitor (PAI-1) in plasma and platelets. British Journal of Haematology, 70, 327-333.
5. Cordell, J.L., Falini, B., Erber, W.N., Ghosh, A.K., Abdulaziz, Z., MacDonald, S., Pulford, A., Stein, H. & Mason, D.Y. (1984) Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes). Journal of Histochemistry and Cytochemistry, 32, 219-229.
6. Dano, K., Andreasen, P.A., Grondahl-Hansen, J., Kristensen, P., Neilsen, L.S. & Skriver, L. (1985) Plasminogen activators, tissue degradation and cancer. Advances in Cancer Research, 44, 139-266.
7. Laurell, C.-B. (1966) Quantitative estimation of proteins by electrophoresis in agarose gel containing antibodies. Analytical Biochemistry, 15, 45-52.
8. MacGregor, I.R., MacDonald, S., Dawes, J., Micklen, L.R. & James, K. (1987) A monoclonal enzyme-linked immunosorbent assay (ELISA) directed towards a fibrin binding region of tissue-type plasminogen activator. Fibrinolysis, 1, 247-252.
9. Markus, G. (1984) The role of hemostasis and fibrinolysis in the metastatic spread of cancer. Seminars on Thrombosis and Hemostasis, 10, 61-70.
10. Mullins, R.E. & Rohrlich, S.T. (1983) The role of proteinases in cellular invasiveness. Biochimica et Biophysica Acta, 695, 177-214.
11. Reith, A.R., Booth, N.A., Moore, N.R., Cruickshank, D.J. & Bennett, B. (1993) Plasminogen activators and inhibitors (PAI-1 and PAI-2) in normal pregnancies, pre-eclampsia and hydatidiform mole. British Journal of Obstetrics and Gynaecology, 100, 370-374.