Inhibition of nematode induced root damage by derivatives of methylenecycloprapane acetic acid

Bioorganic and Medicinal Chemistry Letters

Volumn 7, Issue 20, 1997, Pages 2665-2668

  Pechacek, James T ^a   Bargar, Thomas M ^a   Sabol, Mark R ^a  

^a Discovery Research   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEMATODAL AGENT; METHYLENECYCLOPROPANE ACETIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION RESPONSE; DRUG ACTIVITY; DRUG SYNTHESIS; FATTY ACID OXIDATION; NEMATODE; NONHUMAN; PLANT ROOT; REACTION ANALYSIS;

EID: 0030725570     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(97)10045-2     Document Type: Article

References (16)

1. (a) Duncan, L. W. Annu. Rev. Phytopathol. 1991, 29, 469.
2. 1c
3. th ed.; Worthing, C.; Walker, S., Ed.; The British Crop Protection Council, 1983.
4. Kleier, D. A. Pestic. Sci. 1994, 42, 1.
5. Djian, C.; Ponchet, M.; Cayrol, J. C. Pestic. Biochem. Physiol. 1994, 50, 229.
6. Ruminsky, P. G. International Patent Application WO 92/15555, 1992; Chem. Abstr. 1992, 118, 59302.
7. Baldwin, J. E.; Parker, D. W. J. Org. Chem. 1987, 52, 1475.
8. Satisfactory spectrometric and purity data were obtained for all new compounds.
9. (a) Babin, D.; Pilorge, F.; Delbarre, L. M.; Demoute, J. P. Tetrahedron 1995, 51, 9603.
10. (b) Dolbier, W. R., Jr.; Seabury, M.; Daly, D. J. Org. Chem. 1986, 51, 974.
11. Dauben, W. G.; Shipiro, G. J. Org. Chem. 1984, 49, 4252. We found that the yield of 10 could be significantly improved over that reported by minimizing the time that the product is exposed to 5% HCl in the work up.
12. Lai, M.; Liu, M.; Liu, H. J. Am. Chem. Soc. 1991, 113, 7388.
13. 10b
14. (b) Feng, P.; Patrick, S. Br. J. Pharmac. Chemother. 1958, 13, 125-130.
15. Bell. P; Cheon, S. H.; Fillers, S.; Foley, J.; Fraser, J.; Smith, H.; Young, D.; Revesz, L. Bioorg. Med. Chem. Lett. 1993, 3, 1007.
16. Baumert, D.; Franke, H.; Giles, D.; Hoemberger, A.; Koehn, A.; Skuballa, N.; Wegner, P. in Advances in the Chemistry of Insect Control III; Biggs, G. G., Ed.; Royal Society of Chemistry: Cambridge, 1994; p.171.