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Volumn 17, Issue 2-3, 1997, Pages 125-132

pH: Effects on growth and productivity of cell lines producing monoclonal antibodies: Control in large-scale fermenters

Author keywords

Cell culture; Growth; pH; Productivity

Indexed keywords

MONOCLONAL ANTIBODY;

EID: 0030725121     PISSN: 0959020X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper
Times cited : (20)

References (9)
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    • Amanullah, A., Nienow, A.W., McFarlane, C.M. et at. (1994) Simulation of pH gradients in large scale bioreactors using a scale down model. In Proceedings of the 2nd Conference of Advances in Biochemical Engineering, pp. 2-22.
    • (1994) In Proceedings of the , vol.2 , pp. 2-22
    • Amanullah, A.1    Nienow, A.W.2    McFarlane, C.M.3
  • 3
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    • Culture pH affects expression rates and glycosylation of recombinant mouse placental lactogen proteins by Chinese hamster ovary (CHO) cells
    • Borys, M.C., Linzer, D.I.H. & Papoutsakis, E.T. (1993) Culture pH affects expression rates and glycosylation of recombinant mouse placental lactogen proteins by Chinese hamster ovary (CHO) cells. Bio/Technology, 11, 720-724.
    • (1993) Bio/Technology , vol.11 , pp. 720-724
    • Borys, M.C.1    Linzer, D.I.H.2    Papoutsakis, E.T.3
  • 5
    • 0023639385 scopus 로고
    • Factors governing lactic acid formation in long term cultivation of hybridoma cells
    • Luan, Y.T., Mutharasan, R. & Magee, W.E. (1987) Factors governing lactic acid formation in long term cultivation of hybridoma cells. Biotechnology Letters, 9, 751-756.
    • (1987) Biotechnology Letters , vol.9 , pp. 751-756
    • Luan, Y.T.1    Mutharasan, R.2    Magee, W.E.3
  • 6
    • 84988106827 scopus 로고
    • Kinetic analysis of hybridoma growth and metabolism in batch and continuous culture: Effect of nutrient concentrations, dilution rate and pH
    • Miller, W.M., Blanch, H.W. & Wilke, C.R. (1988) Kinetic analysis of hybridoma growth and metabolism in batch and continuous culture: effect of nutrient concentrations, dilution rate and pH. Biotechnology and Bioengineering, 32, 947-965.
    • (1988) Biotechnology and Bioengineering , vol.32 , pp. 947-965
    • Miller, W.M.1    Blanch, H.W.2    Wilke, C.R.3
  • 7
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    • Homogenisation and oxygen transfer rates in large agitated and sparged animal cell bioreactors: Some implications for growth and production
    • Nienow, A.W., Langheinrich, C., Stevenson, N.C. et al. (1996) Homogenisation and oxygen transfer rates in large agitated and sparged animal cell bioreactors: some implications for growth and production. Oytotechnology, 22, 87-94.
    • (1996) Oytotechnology , vol.22 , pp. 87-94
    • Nienow, A.W.1    Langheinrich, C.2    Stevenson, N.C.3
  • 8
    • 2542508261 scopus 로고    scopus 로고
    • Temperature-a simple parameter for process optimization in fed-batch cultures of recombinant Chinese hamster cvary cells
    • Rossler, B., Lubben, H. & Kretzmer, G. (1996) Temperature-a simple parameter for process optimization in fed-batch cultures of recombinant Chinese hamster cvary cells. Enzyme and Microbial Technology, 18, 423-427.
    • (1996) Enzyme and Microbial Technology , vol.18 , pp. 423-427
    • Rossler, B.1    Lubben, H.2    Kretzmer, G.3
  • 9
    • 0029121771 scopus 로고
    • Enhancement of TPA production under hyperoxic conditions by BHK cells in serum-free and serum-containing cultures
    • Wang, J., Honda, H., Watanabe, H. et al. (1995) Enhancement of TPA production under hyperoxic conditions by BHK cells in serum-free and serum-containing cultures. Journal of Fermentation and Bioengineering, 79, 579-584.
    • (1995) Journal of Fermentation and Bioengineering , vol.79 , pp. 579-584
    • Wang, J.1    Honda, H.2    Watanabe, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.