Use of urine cortisol: Creatinine ratio versus adrenocorticotropic hormone stimulation testing for monitoring mitotane treatment of pituitary-dependent hyperadrenocorticism in dogs

Journal of the American Veterinary Medical Association

Volumn 211, Issue 8, 1997, Pages 1002-1004

  Angles, John M ^a   Feldman, Edward C ^a   Nelson, Richard W ^a   Feldman, Marsha S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MITOTANE;

ANIMAL EXPERIMENT; ARTICLE; CORTICOTROPIN TEST; CREATININE URINE LEVEL; DOG; DRUG MONITORING; HYDROCORTISONE URINE LEVEL; HYPERADRENOCORTICISM; NONHUMAN;

ADRENAL CORTEX; ADRENOCORTICAL HYPERFUNCTION; ADRENOCORTICOTROPIC HORMONE; ANIMALS; ANTINEOPLASTIC AGENTS; CREATININE; DEXAMETHASONE; DOG DISEASES; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; HYDROCORTISONE; MITOTANE; PITUITARY GLAND; PROSPECTIVE STUDIES; REPRODUCIBILITY OF RESULTS;

ANIMALIA; CANIS FAMILIARIS;

EID: 0030725021     PISSN: 00031488     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. Reusch CE, Feldman EC. Canine hyperadrenocorticism due to adrenocortical neoplasia. J Vet Intern Med 1991;5:3-10.
2. Kintzer PP, Peterson ME. Mitotane (o,p'-DDD) treatment of 200 dogs with pituitary-dependent hyperadrenocorticism. J Vet Intern Med 1991;5:182-190.
3. Peterson ME, Gilbertson SR, Drucker WD. Plasma cortisol response to exogenous ACTH in 22 dogs with hyperadrenocorticism caused by an adrenocortical neoplasia. J Am Vet Med Assoc 1982;180:542-544.
4. Peterson ME. Hyperadrenocorticism. Vet Clin North Am Small Anim Pract 1984;14:731-749.
5. Feldman EC, Nelson RW, Feldman MS, et al. Comparison of mitotane treatment for adrenal tumor versus pituitary-dependent hyperadrenocorticism in dogs. J Am Vet Med Assoc 1992; 200:1642-1647.
6. Feldman EC. Comparison of ACTH response and dexamethasone suppression as screening tests in canine hyperadrenocorticism. J Am Vet Med Assoc 1983;182:506-510.
7. Feldman EC. Distinguishing dogs with functioning adrenocortical tumors from dogs with pituitary-dependent hyperadrenocorticism. J Am Vet Med Assoc 1983;183:195-200.
8. Rijnberk A, van Wees A, Mol JA. Assessment of two tests for the diagnosis of canine hyperadrenocorticism. Vet Rec 1988;122:178-180.
9. Feldman EC, Mack RE. Urine cortisolxreatinine ratio as a screening test for hyperadrenocorticism in dogs. J Am Vet Med Assoc 1992;200:1637-1641.
10. Smiley LE, Peterson ME. Evaluation of a urine cortsol:creatinine ratio as a screening test for hyperadrenocorticism in dogs. J Vet Intern Med 1993;7:163-168.
11. Guptill L, Scott-Moncrieff JC, Bottoms G, et al. Use of the urine cortisol:creatinine ratio to monitor treatment response in dogs with pituitary-dependent hyperadrenocorticism. J Am Vet Med Assoc 1997;210:1158-1161.
12. Feldman EC. Effect of functional adrenocortical tumors on plasma cortisol and corticotropin concentrations in dogs. J Am Vet Med Assoc 1981;178:823-826.
13. Barthez PY, Nyland TG, Feldman EC. Ultrasonographic evaluation of the adrenal glands in dogs. J Am Vet Med Assoc 1995;207:1180-1183.