Isolation of a novel kunitz family protease inhibitor in association with Tethya hemolysin from the sponge Tethya ingalli

Journal of Natural Products

Volumn 60, Issue 11, 1997, Pages 1094-1099

  O'Keefe, Barry R ^a   Beutler, John A ^a   Cardellina II, John H ^a   Prather, Tanya R ^a   Shoemaker, Robert H ^a   Sowder II, Raymond C ^b   Henderson, Louis E ^b   Pannell, Lewis K ^c   Boyd, Michael R ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b SAIC FREDERICK INC   (United States)

^c NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APROTININ; HEMOLYSIN; PROTEINASE INHIBITOR;

AMINO TERMINAL SEQUENCE; ARTICLE; CYTOTOXICITY; DRUG ISOLATION; FRACTIONATION; NEW ZEALAND; NONHUMAN; PROTEIN ISOLATION; PROTEINASE INHIBITION; SPONGE (PORIFERA);

AMINO ACID SEQUENCE; AMINO ACIDS; ANIMALS; CELL SURVIVAL; ERYTHROCYTE MEMBRANE; HEMAGGLUTINATION; HEMOLYSIS; HUMANS; ISOELECTRIC FOCUSING; MOLECULAR SEQUENCE DATA; PORIFERA; PROTEASE INHIBITORS; TUMOR CELLS, CULTURED;

HADROMERIDA; PORIFERA; TETHYA; TETHYA INGALLI;

EID: 0030724290     PISSN: 01633864     EISSN: None     Source Type: Journal    
DOI: 10.1021/np970242l     Document Type: Article

References (28)

1. Mebs, D.; Gebauer, E. Toxicon 1980, 18, 97-106.
2. Olivera, B. M.; Gray, W. R.; Zeikus, R.; McIntosh, J. M.; Varga, J.; Rivier, J.; deSantos, V.; Cruz, L. Science 1985, 230, 1338-1343.
3. Schmitz, F. J.; Hollenbeak, K. H.; Campbell, D. C. J. Org. Chem. 1978, 43, 3916-3922.
4. Kobayashi, M.; Tanaka, J.; Katori, T.; Matsuura, M.; Kitigawa, I. Tetrahedron Lett. 1989, 30, 2963-2966.
5. Perry, N. B.; Blunt, J. W.; McCombs, J. D.; Munro, M. H. G. J. Org. Chem. 1986, 51, 5476-5478.
6. Pettit, G. R.; Cichacz, Z. A.; Herald, C. L.; Boyd, M. R.; Schmidt, J. M.; Hooper, J. N. A. J. Org. Chem. 1993, 58, 1302-1304.
7. Hirata, Y.; Uemura, D. Pure Appl. Chem. 1986, 58, 701-710.
8. Smith, G. M.; Djerassi, C. Lipids 1987, 22, 236-240.
9. Tanaka, Y.; Yamamoto, A. Nippon Suisan Gakkaishi 1984, 50, 1787-1791; Chem. Abstr. 1984, 102, 76015d.
10. Tanaka, Y.; Yamamoto, A. Nippon Suisan Gakkaishi 1984, 50, 1787-1791; Chem. Abstr. 1984, 102, 76015d.
11. Mangel, A.; Leitão, J. M.; Batel, R.; Zimmermann, H.; Müller, W. E. G.; Schröder, H. C. Eur. J. Biochem. 1992, 210, 499-507.
12. Wunderer, G.; Machleidt, W.; Fritz, H. Meth. Enzymol. 1981, 80, 816-820.
13. Possani, L. D.; Martin, B. M.; Yatani, A.; Mochca-Morales, J.; Zamudio, F. Z.; Gurrola, G. B.; Brown, A. M. Toxicon 1992, 30, 1343-1364.
14. Ritonja, A.; Meloun, B.; Gubensek, F. Biochim. Biophys. Acta 1983, 746, 138-145.
15. Kato, I.; Tominaga, N. Fed. Proc. 1979, 88, 832.
16. Chan, P.; Salier, J.-P. Biochem. Biophys. Acta 1993, 1174, 195-200.
17. Cechová, D.; Muszynská, G. FEBS Lett. 1970, 8, 84-86.
18. Lever M. J.; Wright, J.; George, S. G. Comp. Biochem. Physiol. Biochem. Mol. Biol. 1994, 108, 275-281.
19. Travis, J.; Salvesen, G. S. Ann. Rev. Biochem. 1983, 52, 655-709.
20. Ikeo, K.; Takahashi, K.; Gojobori, T. J. Mol. Evol. 1992, 34, 536-543.
21. Mebs, D. Toxicon 1994, 32, 1059-1068.
22. Bradford, M. M. Anal. Biochem. 1976, 72, 248-254.
23. Laemmli, U. K. Nature 1970, 227, 680-685.
24. Merrill, C. R.; Goldman, D.; Sedman, S. A.; Ebert, M. H. Science 1981, 211, 1437-1438.
25. Boyd, M. R.; Paull, K. D. Drug Dev. Res. 1995, 34, 91-109.
26. Acton, E. M.; Narayanan, V. L.; Risbood, P.; Shoemaker, R. H.; Vistica, D. T.; Boyd, M. R. J. Med. Chem. 1994, 37, 2185-2189.
27. Scudiero, D.; Shoemaker, R.; Paull, K.; Alley, M.; Monks, A.; Tierney, S.; Nofzinger, T.; Currens, M.; Burkew, D.; Boyd, M. R. Cancer Res. 1988, 48, 4827-4833.
28. Ramesh, N.; Sugumaran, M.; Mole, J. E. J. Biol. Chem. 1988, 263, 11523-11527.