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Volumn 9, Issue 11, 1997, Pages 1101-1107

Natural honey prevents ischaemia-reperfusion-induced gastric mucosal lesions and increased vascular permeability in rats

Author keywords

Gastric lesions; Honey; Ischaemia reperfusion; Non protein sulphhydryls; Oxygen free radicals; Vascular permeability

Indexed keywords

ANTIOXIDANT; DIMETHYL SULFOXIDE; EVANS BLUE; HYDROCHLORIC ACID; THIOL DERIVATIVE; XANTHINE; XANTHINE OXIDASE;

EID: 0030723405     PISSN: 0954691X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00042737-199711000-00014     Document Type: Article
Times cited : (30)

References (52)
  • 1
    • 0023253326 scopus 로고
    • Effect of aspirin plus hydrochloric acid on gastric mucosal microcirculation
    • Kitahora T, Guth PH: Effect of aspirin plus hydrochloric acid on gastric mucosal microcirculation. Gastroenterology 1987, 93:810-817.
    • (1987) Gastroenterology , vol.93 , pp. 810-817
    • Kitahora, T.1    Guth, P.H.2
  • 2
    • 0028049821 scopus 로고
    • Role of gastric blood flow, neutrophil infiltration, and mucosal cell proliferation in gastric adaptation to aspirin in the rat
    • Konturek SJ, Brzozowski T, Stachura J, et al.: Role of gastric blood flow, neutrophil infiltration, and mucosal cell proliferation in gastric adaptation to aspirin in the rat. Gut 1994, 35:1189-1196.
    • (1994) Gut , vol.35 , pp. 1189-1196
    • Konturek, S.J.1    Brzozowski, T.2    Stachura, J.3
  • 3
    • 0025831784 scopus 로고
    • Effect of indomethacin on gastric mucosal blood flow around acetic acid-induced gastric ulcers in rats
    • Hirose H, Takeuchi K, Okabe S: Effect of indomethacin on gastric mucosal blood flow around acetic acid-induced gastric ulcers in rats. Gastroenterology 1991, 100:1259-1265.
    • (1991) Gastroenterology , vol.100 , pp. 1259-1265
    • Hirose, H.1    Takeuchi, K.2    Okabe, S.3
  • 4
    • 0021149780 scopus 로고
    • Histologic and microcirculatory changes in alcohol-induced gastric lesions in the rat. Effect of prostaglandin cytoprotection
    • Guth PH, Paulsen G, Nagata H: Histologic and microcirculatory changes in alcohol-induced gastric lesions in the rat. Effect of prostaglandin cytoprotection. Gastroenterology 1984, 87:1083-1090.
    • (1984) Gastroenterology , vol.87 , pp. 1083-1090
    • Guth, P.H.1    Paulsen, G.2    Nagata, H.3
  • 5
    • 0021951017 scopus 로고
    • Role of oxygen-derived free radicals in hemorrhagic shock-induced gastric lesions in the rat
    • Itoh M, Guth PH: Role of oxygen-derived free radicals in hemorrhagic shock-induced gastric lesions in the rat. Gastroenterology 1985, 88:1162-1167.
    • (1985) Gastroenterology , vol.88 , pp. 1162-1167
    • Itoh, M.1    Guth, P.H.2
  • 6
    • 0022640082 scopus 로고
    • Role of oxygen radicals in ischemia-induced lesions in the cat stomach
    • Perry MA, Wadhwa S, Parks DA, et al.: Role of oxygen radicals in ischemia-induced lesions in the cat stomach. Gastroenterology 1986, 90:362-367.
    • (1986) Gastroenterology , vol.90 , pp. 362-367
    • Perry, M.A.1    Wadhwa, S.2    Parks, D.A.3
  • 7
    • 0023874994 scopus 로고
    • Gradual reintroduction of oxygen reduces reperfusion injury in cat stomach
    • Perry MA, Wadhwa S: Gradual reintroduction of oxygen reduces reperfusion injury in cat stomach. Am J Physiol 1988, 254:G366-G372.
    • (1988) Am J Physiol , vol.254
    • Perry, M.A.1    Wadhwa, S.2
  • 8
    • 0026779345 scopus 로고
    • Sequence of gastric mucosal injury following ischemia and reperfusion: The role of reactive oxygen metabolites
    • Andrews FJ, Malcontenti C, O'Brien PE: Sequence of gastric mucosal injury following ischemia and reperfusion: the role of reactive oxygen metabolites. Dig Dis Sci 1992, 37:1356-1361.
    • (1992) Dig Dis Sci , vol.37 , pp. 1356-1361
    • Andrews, F.J.1    Malcontenti, C.2    O'Brien, P.E.3
  • 9
    • 0025976251 scopus 로고
    • Vitamin E in gastric mucosal injury induced by ischemia-reperfusion
    • Yoshikawa T, Yasuda M, Ueda S, et al.: Vitamin E in gastric mucosal injury induced by ischemia-reperfusion. Am J Clin Nutr 1991, 53:210S-214S.
    • (1991) Am J Clin Nutr , vol.53
    • Yoshikawa, T.1    Yasuda, M.2    Ueda, S.3
  • 10
    • 0028344296 scopus 로고
    • Protection against gastric ischemia-reperfusion injury by nitric oxide generators
    • Andrews FJ, Malcontenti-Wilson C, O'Brien PE: Protection against gastric ischemia-reperfusion injury by nitric oxide generators. Dig Dis Sci 1994, 39:366-373.
    • (1994) Dig Dis Sci , vol.39 , pp. 366-373
    • Andrews, F.J.1    Malcontenti-Wilson, C.2    O'Brien, P.E.3
  • 11
    • 0024604329 scopus 로고
    • Oxygen radicals: Mediators of gastrointestinal pathophysiology
    • Parks DA: Oxygen radicals: mediators of gastrointestinal pathophysiology. Gut 1989, 30:293-298.
    • (1989) Gut , vol.30 , pp. 293-298
    • Parks, D.A.1
  • 12
    • 0029049247 scopus 로고
    • Protective effects of α-tocopherol on gastric mucosal injury by ischaemia-reperfusion in rats
    • Al-Tuwaijiri AS, Al-Dhohaym AD: Protective effects of α-tocopherol on gastric mucosal injury by ischaemia-reperfusion in rats. Med Sci Res 1995, 23:627-628.
    • (1995) Med Sci Res , vol.23 , pp. 627-628
    • Al-Tuwaijiri, A.S.1    Al-Dhohaym, A.D.2
  • 13
    • 8544283516 scopus 로고    scopus 로고
    • Role of oxygen-derived free radicals on gastric mucosal injury induced by ischaemia-reperfusion
    • Ali ATMM, Al-Swayeh OA, Al-Rashed RS, et al.: Role of oxygen-derived free radicals on gastric mucosal injury induced by ischaemia-reperfusion. Saudi J Gastroenterol 1996, 2:19-28.
    • (1996) Saudi J Gastroenterol , vol.2 , pp. 19-28
    • Ali, A.T.M.M.1    Al-Swayeh, O.A.2    Al-Rashed, R.S.3
  • 14
    • 0022657701 scopus 로고
    • Xanthine oxidase inhibitors attenuate ischemia-induced vascular permeability changes in the cat intestine
    • Granger DA, McCord JM, Parks DA, et al.: Xanthine oxidase inhibitors attenuate ischemia-induced vascular permeability changes in the cat intestine. Gastroenterology 1986, 90:80-84.
    • (1986) Gastroenterology , vol.90 , pp. 80-84
    • Granger, D.A.1    McCord, J.M.2    Parks, D.A.3
  • 15
    • 0021984681 scopus 로고
    • Oxygen-derived free radicals in postischaemic tissue injury
    • McCord JM: Oxygen-derived free radicals in postischaemic tissue injury. N Engl J Med 1985, 312:159-163.
    • (1985) N Engl J Med , vol.312 , pp. 159-163
    • McCord, J.M.1
  • 16
    • 0025064708 scopus 로고
    • Hypoxia/reoxygenation increases the permeability of endothelial cell monolayer. Role of oxygen radicals
    • Inauen W, Payne DK, Kvietys PR, et al.: Hypoxia/reoxygenation increases the permeability of endothelial cell monolayer. Role of oxygen radicals. Free Radic Biol Med 1990, 9:219-223.
    • (1990) Free Radic Biol Med , vol.9 , pp. 219-223
    • Inauen, W.1    Payne, D.K.2    Kvietys, P.R.3
  • 17
    • 0026578796 scopus 로고
    • Reoxygenation of endothelial cells increases permeability by oxidant-dependent mechanisms
    • Lum H, Barr DA, Shaffer JR, et al.: Reoxygenation of endothelial cells increases permeability by oxidant-dependent mechanisms. Circ Res 1992, 70:991-998.
    • (1992) Circ Res , vol.70 , pp. 991-998
    • Lum, H.1    Barr, D.A.2    Shaffer, J.R.3
  • 18
    • 0001281521 scopus 로고
    • Composition of honey
    • Edited by Carne E. London; Heinemann
    • White JW Jr: Composition of honey. In Honey. A Comprehensive Survey. Edited by Carne E. London; Heinemann; 1979:157-207.
    • (1979) Honey. A Comprehensive Survey , pp. 157-207
    • White Jr., J.W.1
  • 19
    • 0000054324 scopus 로고
    • Honey regimen in gastrointestinal disorders
    • Proceedings of the First International Islamic Conference on Islamic Medicine, Kuwait
    • Salem SN: Honey regimen in gastrointestinal disorders. In Proceedings of the First International Islamic Conference on Islamic Medicine, Kuwait. Bull Islam Med 1981, 1:358-362.
    • (1981) Bull Islam Med , vol.1 , pp. 358-362
    • Salem, S.N.1
  • 20
    • 0021799773 scopus 로고
    • Honey in the treatment of infantile gastroenteritis
    • Haffeejee IE, Moosa A: Honey in the treatment of infantile gastroenteritis. BMJ 1985, 290:1886-1887.
    • (1985) BMJ , vol.290 , pp. 1886-1887
    • Haffeejee, I.E.1    Moosa, A.2
  • 21
    • 0028825653 scopus 로고
    • Honey may have a laxative effect on normal subjects because of incomplete fructose absorption
    • Ladas SP, Haritos DN, Raptis SA: Honey may have a laxative effect on normal subjects because of incomplete fructose absorption. Am J Clin Nutr 1995, 62:1212-1215.
    • (1995) Am J Clin Nutr , vol.62 , pp. 1212-1215
    • Ladas, S.P.1    Haritos, D.N.2    Raptis, S.A.3
  • 22
    • 0020625648 scopus 로고
    • Acceleration of wound healing by topical application of honey: An animal model
    • Bergman A, Yanai J, Weiss J, et al.: Acceleration of wound healing by topical application of honey: an animal model. Am J Surg 1983, 145:374-376.
    • (1983) Am J Surg , vol.145 , pp. 374-376
    • Bergman, A.1    Yanai, J.2    Weiss, J.3
  • 23
    • 0023713715 scopus 로고
    • Clinical observations on the wound healing properties of honey
    • Efem SEE: Clinical observations on the wound healing properties of honey. Br J Surg 1988, 75:679-681.
    • (1988) Br J Surg , vol.75 , pp. 679-681
    • Efem, S.E.E.1
  • 24
    • 0025793360 scopus 로고
    • Topical application of honey in the treatment of burns
    • Subrahmanyam M: Topical application of honey in the treatment of burns. Br J Surg 1991, 78:497-498.
    • (1991) Br J Surg , vol.78 , pp. 497-498
    • Subrahmanyam, M.1
  • 25
    • 0025937695 scopus 로고
    • A survey of the antibacterial activity of some New Zealand honeys
    • Allen KL, Molan PC, Reid GM: A survey of the antibacterial activity of some New Zealand honeys. J Pharm Pharmacol 1991, 43:817-822.
    • (1991) J Pharm Pharmacol , vol.43 , pp. 817-822
    • Allen, K.L.1    Molan, P.C.2    Reid, G.M.3
  • 27
    • 0000442508 scopus 로고
    • Natural honey prevents indomethacin and ethanol-induced gastric lesions in rats
    • Ali ATMM, Al-Humayyd MS, Madan BR: Natural honey prevents indomethacin and ethanol-induced gastric lesions in rats. Saudi Med J 1990, 11:275-279.
    • (1990) Saudi Med J , vol.11 , pp. 275-279
    • Ali, A.T.M.M.1    Al-Humayyd, M.S.2    Madan, B.R.3
  • 28
    • 0025972782 scopus 로고
    • Prevention of ethanol-induced gastric lesions in rats by natural honey, and its possible mechanism of action
    • Ali ATMM: Prevention of ethanol-induced gastric lesions in rats by natural honey, and its possible mechanism of action. Scand J Gastroenterol 1991, 26:281-288.
    • (1991) Scand J Gastroenterol , vol.26 , pp. 281-288
    • Ali, A.T.M.M.1
  • 29
    • 0029185587 scopus 로고
    • Natural honey exerts its protective effects against ethanol-induced gastric lesions in rats by preventing depletion of glandular nonprotein sulfhydryls
    • Ali ATMM: Natural honey exerts its protective effects against ethanol-induced gastric lesions in rats by preventing depletion of glandular nonprotein sulfhydryls. Trop Gastroenterol 1995, 16:18-26.
    • (1995) Trop Gastroenterol , vol.16 , pp. 18-26
    • Ali, A.T.M.M.1
  • 30
    • 0029131928 scopus 로고
    • Natural honey accelerates healing of indomethacin-induced antral ulcers in rats
    • Ali ATMM: Natural honey accelerates healing of indomethacin-induced antral ulcers in rats. Saudi Med J 1995, 16:161-166.
    • (1995) Saudi Med J , vol.16 , pp. 161-166
    • Ali, A.T.M.M.1
  • 31
    • 9544226438 scopus 로고    scopus 로고
    • The role of nitric oxide in gastric protection by honey
    • Ali ATMM, Al-Swayeh OA: The role of nitric oxide in gastric protection by honey. Saudi Med J 1996, 17:301-306.
    • (1996) Saudi Med J , vol.17 , pp. 301-306
    • Ali, A.T.M.M.1    Al-Swayeh, O.A.2
  • 32
    • 0021028952 scopus 로고
    • Effects of an antiulcer drug, sucralfate (a basic aluminium salt of sulfated disaccharide), on experimental gastric lesions and gastric secretion in rats
    • Okabe S, Takeuchi K, Kunimi H, et al.: Effects of an antiulcer drug, sucralfate (a basic aluminium salt of sulfated disaccharide), on experimental gastric lesions and gastric secretion in rats. Dig Dis Sci 1983, 28:1034-1042.
    • (1983) Dig Dis Sci , vol.28 , pp. 1034-1042
    • Okabe, S.1    Takeuchi, K.2    Kunimi, H.3
  • 34
    • 0025347282 scopus 로고
    • Evidence of antioxidant role of sucralphate in gastric mucosal protection
    • Laudanno OM, Bedini OA, Cesolari JA, et al.: Evidence of antioxidant role of sucralphate in gastric mucosal protection. Ital J Gastroenterol 1990, 22:19-21.
    • (1990) Ital J Gastroenterol , vol.22 , pp. 19-21
    • Laudanno, O.M.1    Bedini, O.A.2    Cesolari, J.A.3
  • 35
    • 0026310669 scopus 로고
    • Sucralphate in the prevention of acute gastric lesions induced by ischemia-reperfusion
    • Laudanno OM, Bedini OA, Cesolari JA, et al.: Sucralphate in the prevention of acute gastric lesions induced by ischemia-reperfusion. Acta Gastroenterol Latinoam 1992, 21:85-88.
    • (1992) Acta Gastroenterol Latinoam , vol.21 , pp. 85-88
    • Laudanno, O.M.1    Bedini, O.A.2    Cesolari, J.A.3
  • 36
    • 0026726639 scopus 로고
    • Sucralphate in the prevention of acute gastric lesions induced by ischemia-reperfusion
    • Eaudanno OM, Bedini OA, Cesolari JA, et al.: Sucralphate in the prevention of acute gastric lesions induced by ischemia-reperfusion. Ital J Gastroenterol 1992, 24:380-382.
    • (1992) Ital J Gastroenterol , vol.24 , pp. 380-382
    • Eaudanno, O.M.1    Bedini, O.A.2    Cesolari, J.A.3
  • 37
    • 85044683339 scopus 로고    scopus 로고
    • The potential synergistic effect of calcium channel blockers and α-tocopherol on gastric mucosal injury induced by ischemia-reperfusion
    • Al- Dhohyan AD, Al-Tuwaijiri AS: The potential synergistic effect of calcium channel blockers and α-tocopherol on gastric mucosal injury induced by ischemia-reperfusion. Eur J Gastroenterol Hepatol 1996, 8:1-4.
    • (1996) Eur J Gastroenterol Hepatol , vol.8 , pp. 1-4
    • Al-Dhohyan, A.D.1    Al-Tuwaijiri, A.S.2
  • 38
    • 0022006479 scopus 로고
    • Early vascular injury and increased vascular permeability in gastric mucosal injury caused by ethanol in the rat
    • Szabo S, Trier JS, Brown A, et al.: Early vascular injury and increased vascular permeability in gastric mucosal injury caused by ethanol in the rat. Gastroenterology 1985, 88:228-236.
    • (1985) Gastroenterology , vol.88 , pp. 228-236
    • Szabo, S.1    Trier, J.S.2    Brown, A.3
  • 39
    • 0023819229 scopus 로고
    • Intragastric accumulation of Evans blue as a method for assessing aspirin-induced acute gastric mucosal injury in humans
    • Woods KL, Smith JL, Graham DY: Intragastric accumulation of Evans blue as a method for assessing aspirin-induced acute gastric mucosal injury in humans. Dig Dis Sci 1988, 33:769-773.
    • (1988) Dig Dis Sci , vol.33 , pp. 769-773
    • Woods, K.L.1    Smith, J.L.2    Graham, D.Y.3
  • 40
    • 0028012640 scopus 로고
    • Evans blue permeation of intestinal mucosa in the rat
    • Lange S, Delbro DS, Jennisch E: Evans blue permeation of intestinal mucosa in the rat. Scand J Gastroenterol 1994, 29:38-46.
    • (1994) Scand J Gastroenterol , vol.29 , pp. 38-46
    • Lange, S.1    Delbro, D.S.2    Jennisch, E.3
  • 41
    • 0024512245 scopus 로고
    • Role of sulfhydryls in mucosal injury caused by ethanol: Relation to microvascular permeability, gastric motility and cytoprotection
    • Takeuchi K, Okada M, Niida H, et al.: Role of sulfhydryls in mucosal injury caused by ethanol: relation to microvascular permeability, gastric motility and cytoprotection. J Pharmacol Exp Ther 1989, 248:836-842.
    • (1989) J Pharmacol Exp Ther , vol.248 , pp. 836-842
    • Takeuchi, K.1    Okada, M.2    Niida, H.3
  • 42
    • 0014428865 scopus 로고
    • Estimation of total, protein-bound, and nonprotein sulphydryl groups in tissue with Ellman's reagent
    • Sedlak J, Lindsay RH: Estimation of total, protein-bound, and nonprotein sulphydryl groups in tissue with Ellman's reagent. Anal Biochem 1968, 25:192-205.
    • (1968) Anal Biochem , vol.25 , pp. 192-205
    • Sedlak, J.1    Lindsay, R.H.2
  • 43
    • 0025851574 scopus 로고
    • Scavenger effect of sulfasalazine, 5-aminosalicylic acid, and olsalazine on superoxide radical generation
    • Gionchetti P, Guarnieri C, Campieri M, et al.: Scavenger effect of sulfasalazine, 5-aminosalicylic acid, and olsalazine on superoxide radical generation. Dig Dis Sci 1991, 36:174-178.
    • (1991) Dig Dis Sci , vol.36 , pp. 174-178
    • Gionchetti, P.1    Guarnieri, C.2    Campieri, M.3
  • 45
    • 0018195287 scopus 로고
    • The glutathione status of the cells
    • Kosower NS, Kosower EM: The glutathione status of the cells. Int Rev Cytol 1978, 54:109-160.
    • (1978) Int Rev Cytol , vol.54 , pp. 109-160
    • Kosower, N.S.1    Kosower, E.M.2
  • 46
    • 0019825246 scopus 로고
    • Sulfhydryl compounds may mediate cytoprotection
    • Szabo S, Trier JS, Frankel PW: Sulfhydryl compounds may mediate cytoprotection. Science 1981, 214:200-202.
    • (1981) Science , vol.214 , pp. 200-202
    • Szabo, S.1    Trier, J.S.2    Frankel, P.W.3
  • 47
    • 0023845318 scopus 로고
    • Glutathione modulates toxic oxygen metabolite injury of canine chief cell monolayer in primary culture
    • Olson CE: Glutathione modulates toxic oxygen metabolite injury of canine chief cell monolayer in primary culture. Am J Physiol 1988, 254:G49-G56.
    • (1988) Am J Physiol , vol.254
    • Olson, C.E.1
  • 48
    • 0025940277 scopus 로고
    • Drug antioxidant effects. A basis for drug selection
    • Halliwell B: Drug antioxidant effects. A basis for drug selection. Drugs 1991, 42:569-605.
    • (1991) Drugs , vol.42 , pp. 569-605
    • Halliwell, B.1
  • 49
    • 0027414717 scopus 로고
    • Glutathione prevents ethanol-induced gastric mucosal damage and depletion of sulfhydryl compounds in human
    • Loguercio C, Taranto D, Beneduce F, et al.: Glutathione prevents ethanol-induced gastric mucosal damage and depletion of sulfhydryl compounds in human. Gut 1993, 34:161-165.
    • (1993) Gut , vol.34 , pp. 161-165
    • Loguercio, C.1    Taranto, D.2    Beneduce, F.3
  • 50
    • 0019478520 scopus 로고
    • Protective role of glutathione redox cycle against adriamycin-induced toxicity in isolated hepatocytes
    • Babson JR, Abell NS, Reed DJ: Protective role of glutathione redox cycle against adriamycin-induced toxicity in isolated hepatocytes. Biochem Pharmacol 1981, 30:2299-2304.
    • (1981) Biochem Pharmacol , vol.30 , pp. 2299-2304
    • Babson, J.R.1    Abell, N.S.2    Reed, D.J.3
  • 52
    • 0019367111 scopus 로고
    • Mechanistic aspects of enhanced lipid peroxidation following glutathione depletion in vivo
    • Younes M, Siegers CP: Mechanistic aspects of enhanced lipid peroxidation following glutathione depletion in vivo. Chem Biol Interact 1981, 34:257-266.
    • (1981) Chem Biol Interact , vol.34 , pp. 257-266
    • Younes, M.1    Siegers, C.P.2


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