-
1
-
-
1842396712
-
-
Dallas: American Heart Association
-
American Heart Association. 1997 statistical supplement. Dallas: American Heart Association; 1997.
-
(1997)
1997 Statistical Supplement
-
-
-
2
-
-
0017643309
-
The wavefront phenomenon of ischemic cell death. I. Myocardial infarct size vs duration of coronary occlusion in dogs
-
Reimer KA, Lowe JE, Rasmussen MM et al. The wavefront phenomenon of ischemic cell death. I. Myocardial infarct size vs duration of coronary occlusion in dogs. Circulation. 1977; 56:786-94.
-
(1977)
Circulation
, vol.56
, pp. 786-794
-
-
Reimer, K.A.1
Lowe, J.E.2
Rasmussen, M.M.3
-
3
-
-
0027176652
-
Perihospital-initiated vs hospital-initiated thrombolytic therapy
-
Weaver WD, Cerqueira M, Hallstrom AP et al. Perihospital-initiated vs hospital-initiated thrombolytic therapy. JAMA. 1993; 270:1211-6.
-
(1993)
JAMA
, vol.270
, pp. 1211-1216
-
-
Weaver, W.D.1
Cerqueira, M.2
Hallstrom, A.P.3
-
4
-
-
0027428966
-
Prehospital thrombolysis: Beneficial effects of very early treatment on Infarct size and left ventricular function
-
Linderer T, Schröder R, Arntz R et al. Prehospital thrombolysis: beneficial effects of very early treatment on Infarct size and left ventricular function. J Am Coll Cardiol. 1993; 22:1304-10.
-
(1993)
J Am Coll Cardiol
, vol.22
, pp. 1304-1310
-
-
Linderer, T.1
Schröder, R.2
Arntz, R.3
-
5
-
-
0027295373
-
Late Assessment of Thrombolytic Efficacy (LATE) study with alteplase 6-24 hours after onset of acute myocardial infarction
-
LATE Study Group. Late Assessment of Thrombolytic Efficacy (LATE) study with alteplase 6-24 hours after onset of acute myocardial infarction. Lancet. 1993; 342:759-66.
-
(1993)
Lancet
, vol.342
, pp. 759-766
-
-
-
6
-
-
0023804907
-
Six- and twelve-month follow-up of the phase I Thrombolysis in Myocardial Infarction (TIMI) trial
-
Dalen JE, Gore JM, Braunwald E et al. Six- and twelve-month follow-up of the phase I Thrombolysis in Myocardial Infarction (TIMI) trial. Am J Cardiol. 1988; 62:179-85.
-
(1988)
Am J Cardiol
, vol.62
, pp. 179-185
-
-
Dalen, J.E.1
Gore, J.M.2
Braunwald, E.3
-
7
-
-
0025118412
-
Consequences of reocclusion after successful reperfusion therapy in acute myocardial infarction
-
Ohman EM, Califf RM, Topol EJ et al. Consequences of reocclusion after successful reperfusion therapy in acute myocardial infarction. Circulation. 1990; 82:781-91.
-
(1990)
Circulation
, vol.82
, pp. 781-791
-
-
Ohman, E.M.1
Califf, R.M.2
Topol, E.J.3
-
8
-
-
0029166814
-
Effect of infarct artery patency on prognosis after acute myocardial infarction
-
Lamas GA, Flaker GC, Mitchell G et al. Effect of infarct artery patency on prognosis after acute myocardial infarction. Circulation. 1995; 92:1101-9.
-
(1995)
Circulation
, vol.92
, pp. 1101-1109
-
-
Lamas, G.A.1
Flaker, G.C.2
Mitchell, G.3
-
9
-
-
0027172657
-
TIMI perfusion grade 3 but not grade 2 results in improved outcome after thrombolysis for myocardial infarction
-
Anderson JL, Karagounis LA, Becker LC et al. TIMI perfusion grade 3 but not grade 2 results in improved outcome after thrombolysis for myocardial infarction. Circulation. 1993; 87:1829-39.
-
(1993)
Circulation
, vol.87
, pp. 1829-1839
-
-
Anderson, J.L.1
Karagounis, L.A.2
Becker, L.C.3
-
10
-
-
0027245839
-
Impact of early perfusion status of the infarct-related artery on short-term mortality after thrombolysis for acute myocardial infarction: Retrospective analysis of our German multicenter studies
-
Vogt A, von Essen R, Tebbe U et al. Impact of early perfusion status of the infarct-related artery on short-term mortality after thrombolysis for acute myocardial infarction: retrospective analysis of our German multicenter studies. J Am Coll Cardiol. 1993; 21:1391-5.
-
(1993)
J Am Coll Cardiol
, vol.21
, pp. 1391-1395
-
-
Vogt, A.1
Von Essen, R.2
Tebbe, U.3
-
11
-
-
0027424433
-
The effects of tissue plasminogen activator, streptokinase, or both on coronary-artery patency, ventricular function, and survival after acute myocardial infarction
-
GUSTO Angiographic Investigators. The effects of tissue plasminogen activator, streptokinase, or both on coronary-artery patency, ventricular function, and survival after acute myocardial infarction. N Engl J Med. 1993; 329:1615-22.
-
(1993)
N Engl J Med
, vol.329
, pp. 1615-1622
-
-
-
12
-
-
0028914981
-
Link between the angiographic substudy and mortality outcomes in a large randomized trial of myocardial reperfusion: Importance of early and complete infarct artery reperfusion
-
Simes RJ, Topol EJ, Holmes DR Jr et al. Link between the angiographic substudy and mortality outcomes in a large randomized trial of myocardial reperfusion: importance of early and complete infarct artery reperfusion. Circulation. 1995; 91:1923-8.
-
(1995)
Circulation
, vol.91
, pp. 1923-1928
-
-
Simes, R.J.1
Topol, E.J.2
Holmes Jr., D.R.3
-
13
-
-
0020308918
-
Beneficial effects of intracoronary thrombolysis up to eighteen hours after onset of pain in evolving myocardial infarction
-
Smalling RW, Fuentes F, Freund GC et al. Beneficial effects of intracoronary thrombolysis up to eighteen hours after onset of pain in evolving myocardial infarction. Am Heart J. 1982; 104:912-20.
-
(1982)
Am Heart J
, vol.104
, pp. 912-920
-
-
Smalling, R.W.1
Fuentes, F.2
Freund, G.C.3
-
14
-
-
0022640774
-
Effectiveness of intravenous thrombolytic treatment in acute myocardial Infarction
-
Gruppo Italiano per lo Studio della Streptochinasi nell'Infarto Miocardico (GISSI). Effectiveness of intravenous thrombolytic treatment in acute myocardial Infarction. Lancet. 1986; 1:397-401.
-
(1986)
Lancet
, vol.1
, pp. 397-401
-
-
-
15
-
-
84913702444
-
Long-term effects of intravenous thrombolysis in acute myocardial infarction: Final report of the GISSI study
-
Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico (GISSI). Long-term effects of intravenous thrombolysis in acute myocardial infarction: final report of the GISSI study. Lancet. 1987; 2:871-4.
-
(1987)
Lancet
, vol.2
, pp. 871-874
-
-
-
16
-
-
0023805341
-
Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2
-
ISIS-2 (Second International Study of Infarct Survival) Collaborative Group. Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2. Lancet. 1988; 2:349-60.
-
(1988)
Lancet
, vol.2
, pp. 349-360
-
-
-
17
-
-
0023258694
-
Thrombolysis in Myocardial Infarction (TIMI) trial, phase I: A comparison between intravenous tissue plasminogen activator and intravenous streptokinase
-
Chesebro JH, Knatterud G, Roberts R et al. Thrombolysis in Myocardial Infarction (TIMI) trial, phase I: a comparison between intravenous tissue plasminogen activator and intravenous streptokinase. Circulation. 1987; 76:142-54.
-
(1987)
Circulation
, vol.76
, pp. 142-154
-
-
Chesebro, J.H.1
Knatterud, G.2
Roberts, R.3
-
18
-
-
0023179843
-
A multicenter, randomized placebo-controlled trial of a new form of intravenous recombinant tissue-type plasminogen activator (Activase) in acute myocardial infarction
-
Topol EJ, Morris DC, Smalling RW et al. A multicenter, randomized placebo-controlled trial of a new form of intravenous recombinant tissue-type plasminogen activator (Activase) in acute myocardial infarction. J Am Coll Cardiol. 1987; 9:1205-13.
-
(1987)
J Am Coll Cardiol
, vol.9
, pp. 1205-1213
-
-
Topol, E.J.1
Morris, D.C.2
Smalling, R.W.3
-
19
-
-
0028337135
-
Dose finding with a novel recombinant plasminogen activator (BM 06. 022) in patients with acute myocardial infarction: Results of the German Recombinant Plasminogen Activator Study
-
Neuhaus KL, von Essen R, Vogt A et al. Dose finding with a novel recombinant plasminogen activator (BM 06. 022) in patients with acute myocardial infarction: results of the German Recombinant Plasminogen Activator Study. J Am Coll Cardiol. 1994; 24:55-60.
-
(1994)
J Am Coll Cardiol
, vol.24
, pp. 55-60
-
-
Neuhaus, K.L.1
Von Essen, R.2
Vogt, A.3
-
20
-
-
0025231286
-
Improved infarct-related arterial patency after high dose, weight-adjusted, rapid infusion of tissue-type plasminogen activator in myocardial infarction: Results of a multicenter randomized trial of two dosage requirements
-
Smalling RW, Schumacher R, Morris D et al. Improved infarct-related arterial patency after high dose, weight-adjusted, rapid infusion of tissue-type plasminogen activator in myocardial infarction: results of a multicenter randomized trial of two dosage requirements. J Am Coll Cardiol. 1990; 15:915-21.
-
(1990)
J Am Coll Cardiol
, vol.15
, pp. 915-921
-
-
Smalling, R.W.1
Schumacher, R.2
Morris, D.3
-
21
-
-
0025335032
-
A factorial randomized trial of alteplase versus streptokinase and heparin versus no heparin among 12,490 patients with acute myocardial infarction
-
Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico: GISSI-2. A factorial randomized trial of alteplase versus streptokinase and heparin versus no heparin among 12,490 patients with acute myocardial infarction. Lancet. 1990; 336:65-71.
-
(1990)
Lancet
, vol.336
, pp. 65-71
-
-
-
22
-
-
0026607185
-
ISIS-3: A randomised comparison of strep- tokinase vs, tissue plasminogen activator vs anistreplase and of aspirin plus heparin vs aspirin alone among 41,299 cases of suspected acute myocardial infarction
-
ISIS-3 (Third International Study of Infarct Survival) Collab- orative Group. ISIS-3: a randomised comparison of strep- tokinase vs, tissue plasminogen activator vs anistreplase and of aspirin plus heparin vs aspirin alone among 41,299 cases of suspected acute myocardial infarction. Lancet. 1992; 339:753-70
-
(1992)
Lancet
, vol.339
, pp. 753-770
-
-
-
23
-
-
0027240597
-
An international randomized trial comparing four thrombolytic strategies for acute myocardial infarction
-
GUSTO Investigators. An international randomized trial comparing four thrombolytic strategies for acute myocardial infarction. N Engl J Med. 1993; 329:673-82.
-
(1993)
N Engl J Med
, vol.329
, pp. 673-682
-
-
-
24
-
-
0025329267
-
In-hospital mortality and clinical course of 20,891 patients with suspected acute myocardial Infarction randomised between alteplase and streptokinase with or without heparin
-
International Study Group. In-hospital mortality and clinical course of 20,891 patients with suspected acute myocardial Infarction randomised between alteplase and streptokinase with or without heparin. Lancet. 1990; 336:71-5.
-
(1990)
Lancet
, vol.336
, pp. 71-75
-
-
-
25
-
-
0030593897
-
Molecular biology of plasminogen activators: What are the clinical implications of drug design?
-
Smalling RW. Molecular biology of plasminogen activators: what are the clinical implications of drug design? Am J Cardiol. 1996; 78(suppl 12A):2-7.
-
(1996)
Am J Cardiol.
, vol.78
, Issue.SUPPL. 12A
, pp. 2-7
-
-
Smalling, R.W.1
-
26
-
-
0026698150
-
Thrombolytic therapy for acute myocardial infarction: A review
-
Granger CB, Califf RM, Topol EJ. Thrombolytic therapy for acute myocardial infarction: a review. Drugs. 1992; 44:293-325.
-
(1992)
Drugs
, vol.44
, pp. 293-325
-
-
Granger, C.B.1
Califf, R.M.2
Topol, E.J.3
-
27
-
-
0026100158
-
Intracerebral hemorrhage, cerebral infarction, and subdural hematoma after acute myocardial infarction and thrombolytic therapy in the Thrombolysis in Myocardial Infarction Study
-
Gore JM, Sloan M, Price TR et al. Intracerebral hemorrhage, cerebral infarction, and subdural hematoma after acute myocardial infarction and thrombolytic therapy in the Thrombolysis in Myocardial Infarction Study. Circulation. 1991; 83:448-59.
-
(1991)
Circulation
, vol.83
, pp. 448-459
-
-
Gore, J.M.1
Sloan, M.2
Price, T.R.3
-
28
-
-
0028785426
-
Stroke after thrombolysis: Mortality and functional outcomes in the GUSTO-1 trial
-
Gore JM, Granger CB, Simoons ML et al. Stroke after thrombolysis: mortality and functional outcomes in the GUSTO-1 trial. Circulation. 1995; 92:2811-8.
-
(1995)
Circulation
, vol.92
, pp. 2811-2818
-
-
Gore, J.M.1
Granger, C.B.2
Simoons, M.L.3
-
29
-
-
0027527617
-
Individual risk assessment for intracranial haemorrhage during thrombolytic therapy
-
Simoons ML, Maggioni AP, Knatterud G et al. Individual risk assessment for intracranial haemorrhage during thrombolytic therapy. Lancet. 1993; 342:1523-8.
-
(1993)
Lancet
, vol.342
, pp. 1523-1528
-
-
Simoons, M.L.1
Maggioni, A.P.2
Knatterud, G.3
-
30
-
-
0025002426
-
Molecular biologic modification of plasminogen activators, an artful science
-
Loscalzo J. Molecular biologic modification of plasminogen activators, an artful science. Circulation. 1990; 82:1062-3.
-
(1990)
Circulation
, vol.82
, pp. 1062-1063
-
-
Loscalzo, J.1
-
33
-
-
0029971782
-
The recombinant Escherichia coli-derived protease-domain of tissue-type plasminogen activator is a potent and fibrin specific fibrinolytic agent
-
Abstract
-
Kohnert U, Hellerbrand K, Martin U et al. The recombinant Escherichia coli-derived protease-domain of tissue-type plasminogen activator is a potent and fibrin specific fibrinolytic agent. Fibrinolysis. 1996; 1-10. Abstract.
-
(1996)
Fibrinolysis
, pp. 1-10
-
-
Kohnert, U.1
Hellerbrand, K.2
Martin, U.3
-
34
-
-
0027725185
-
BM 06. 022: A novel recombinant plasminogen activator
-
Martin U, Bader R, Bohm E et al. BM 06. 022: a novel recombinant plasminogen activator. Cardiovasc Drug Rev. 1993; 11:299-311.
-
(1993)
Cardiovasc Drug Rev
, vol.11
, pp. 299-311
-
-
Martin, U.1
Bader, R.2
Bohm, E.3
-
35
-
-
0026575312
-
Biochemical properties of the kringle 2 and protease domains are maintained in the refolded t-PA deletion variant BM 06. 022
-
Kohnert U, Rudolph R, Verheijen JH et al. Biochemical properties of the kringle 2 and protease domains are maintained in the refolded t-PA deletion variant BM 06. 022. Protein Eng. 1992; 5:93-100.
-
(1992)
Protein Eng
, vol.5
, pp. 93-100
-
-
Kohnert, U.1
Rudolph, R.2
Verheijen, J.H.3
-
36
-
-
0025786951
-
Coronary thrombolytic properties of a novel recombinant plasminogen activator (BM 06. 022) in a canine model
-
Martin U, Fischer S, Kohnert U et al. Coronary thrombolytic properties of a novel recombinant plasminogen activator (BM 06. 022) in a canine model. J Cardiovasc Pharmacol. 1991; 18:111-9.
-
(1991)
J Cardiovasc Pharmacol
, vol.18
, pp. 111-119
-
-
Martin, U.1
Fischer, S.2
Kohnert, U.3
-
37
-
-
0026595548
-
Evaluation of thrombolytic and systemic effects of the novel recombinant plasminogen activator BM 06. 022 compared with alteplase, anistreplase, streptokinase and urokinase in a canine model of coronary artery thrombosis
-
Martin Y, Sponer G, Strein K. Evaluation of thrombolytic and systemic effects of the novel recombinant plasminogen activator BM 06. 022 compared with alteplase, anistreplase, streptokinase and urokinase In a canine model of coronary artery thrombosis. J Am Coll Cardiol 1992; 19:433-40.
-
(1992)
J Am Coll Cardiol
, vol.19
, pp. 433-440
-
-
Martin, Y.1
Sponer, G.2
Strein, K.3
-
38
-
-
0027203680
-
Open, noncontrolled dose-finding study with a novel recombinant plasminogen activator (BM 06. 022) given as a double bolus in patients with acute myocardial infarction
-
Tebbe U, von Essen R, Smolarz A et al. Open, noncontrolled dose-finding study with a novel recombinant plasminogen activator (BM 06. 022) given as a double bolus in patients with acute myocardial infarction. Am J Cardiol. 1993; 72:518-24.
-
(1993)
Am J Cardiol
, vol.72
, pp. 518-524
-
-
Tebbe, U.1
Von Essen, R.2
Smolarz, A.3
-
39
-
-
0024427474
-
Improved thrombolysis with a modified dose regimen of recombinant tissue-type plasminogen activator
-
Neuhaus KL, Feuerer W, Jeep-Tebbe S et al. Improved thrombolysis with a modified dose regimen of recombinant tissue-type plasminogen activator. J Am Coll Cardiol. 1989; 14:1566-9.
-
(1989)
J Am Coll Cardiol
, vol.14
, pp. 1566-1569
-
-
Neuhaus, K.L.1
Feuerer, W.2
Jeep-Tebbe, S.3
-
40
-
-
0029142436
-
Randomised, double-blind comparison of reteplase double-bolus administration with streptokinase in acute myocardial infarction (INJECT): Trial to investigate equivalence
-
International Joint Efficacy Comparison of Thrombolytics
-
International Joint Efficacy Comparison of Thrombolytics. Randomised, double-blind comparison of reteplase double-bolus administration with streptokinase in acute myocardial infarction (INJECT): trial to investigate equivalence. Lancet. 1995; 346:329-36.
-
(1995)
Lancet
, vol.346
, pp. 329-336
-
-
-
41
-
-
0029066701
-
More rapid, complete, and stable coronary thrombolysis with bolus administration of reteplase compared with alteplase infusion in acute myocardial infarction
-
Smalling RW, Bode C, Kalbfleisch J et al. More rapid, complete, and stable coronary thrombolysis with bolus administration of reteplase compared with alteplase infusion in acute myocardial infarction. Circulation. 1995; 91:2725-32.
-
(1995)
Circulation
, vol.91
, pp. 2725-2732
-
-
Smalling, R.W.1
Bode, C.2
Kalbfleisch, J.3
-
42
-
-
0343849937
-
Randomized comparison of coronary thrombolysis achieved with double-bolus reteplase (recombinant plasminogen activator) and front loaded, accelerated alteplase (recombinant tissue plasminogen activator) in patients with acute myocardial infarction
-
Bode C, Smalling RW, Berg G et al. Randomized comparison of coronary thrombolysis achieved with double-bolus reteplase (recombinant plasminogen activator) and front loaded, accelerated alteplase (recombinant tissue plasminogen activator) in patients with acute myocardial infarction. Circulation. 1996; 94:891-8.
-
(1996)
Circulation
, vol.94
, pp. 891-898
-
-
Bode, C.1
Smalling, R.W.2
Berg, G.3
-
43
-
-
23444439163
-
A faster-acting and more. potent form of tissue plasminogen activator
-
Keyt BA, Paoni NF, Refino CJ et al. A faster-acting and more. potent form of tissue plasminogen activator. Proc Natl Acad Sci USA. 1994; 91:3670-4.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 3670-3674
-
-
Keyt, B.A.1
Paoni, N.F.2
Refino, C.J.3
-
44
-
-
0028021209
-
A long half-life and fibrin-specific form of tissue plasminogen activator in rabbit models of embolic stroke and peripheral bleeding
-
Thomas GR, Thibodeaux H, Errett CJ et al. A long half-life and fibrin-specific form of tissue plasminogen activator in rabbit models of embolic stroke and peripheral bleeding. Stroke. 1994; 25:2072-9.
-
(1994)
Stroke
, vol.25
, pp. 2072-2079
-
-
Thomas, G.R.1
Thibodeaux, H.2
Errett, C.J.3
-
45
-
-
0028821715
-
New variant of human tissue plasminogen activator (TPA) with enhanced efficacy and lower incidence of bleeding compared with recombinant human TPA
-
Benedict CR, Refino CJ, Keyt BA et al. New variant of human tissue plasminogen activator (TPA) with enhanced efficacy and lower incidence of bleeding compared with recombinant human TPA. Circulation. 1995; 92:3032-40.
-
(1995)
Circulation
, vol.92
, pp. 3032-3040
-
-
Benedict, C.R.1
Refino, C.J.2
Keyt, B.A.3
-
47
-
-
0025837875
-
Protein engineering of novel plasminogen activators with increased thrombolytic potency in rabbits relative to activase
-
Larsen GR, Timony GA, Horgan PG et al. Protein engineering of novel plasminogen activators with increased thrombolytic potency in rabbits relative to activase. J Biol Chem. 1991; 266:8156-61.
-
(1991)
J Biol Chem
, vol.266
, pp. 8156-8161
-
-
Larsen, G.R.1
Timony, G.A.2
Horgan, P.G.3
-
48
-
-
0028018459
-
Trials in acute myocardial infarction
-
Ohman EM. Trials in acute myocardial infarction. J Myocard Ischemia. 1994; 6:24-31.
-
(1994)
J Myocard Ischemia
, vol.6
, pp. 24-31
-
-
Ohman, E.M.1
-
49
-
-
0029835392
-
A comparison of recombinant hirudin with heparin for the treatment of acute coronary syndromes
-
Global Use of Strategies to Open Occluded Coronary Arteries (GUSTO) IIb Investigators
-
Global Use of Strategies to Open Occluded Coronary Arteries (GUSTO) IIb Investigators. A comparison of recombinant hirudin with heparin for the treatment of acute coronary syndromes. N Engl J Med. 1996; 335:775-82.
-
(1996)
N Engl J Med
, vol.335
, pp. 775-782
-
-
|