A new procedure for α-hydroxylation of ketones using thallium(III) p-nitrobenzenesulfonate (TNS)

Synthetic Communications

Volumn 27, Issue 23, 1997, Pages 4079-4084

  Lee, Jong Chan ^a   Park, Chunkyung ^a   Choi, Youngsup ^a  

^a Chung Ang University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

KETOL;

ARTICLE; DRUG SYNTHESIS; HYDROXYLATION; IN VITRO STUDY; METHODOLOGY; REACTION ANALYSIS;

EID: 0030721573     PISSN: 00397911     EISSN: None     Source Type: Journal    
DOI: 10.1080/00397919708005454     Document Type: Article

References (9)

1. Raduchel, B, Synthesis 1980, 292.
2. A. B. Jones in Comprehensive Organic Synthesis, Trost , B. M., Ed., Vol. 7, Chapter 2.3, Pergamon Press, Oxford, 1991.
3. McKillop, A., Hunt, J. D., and Taylor, E. C., J. Org. Chem. , 1972, 37, 3381.
4. Moriarty, R. M., Berglund, B. A., and Penmasta, R., Tetrahedron Lett., 1992, 33, 6065.
5. Khanna, M. S., Garg, C. P., and Kapoor, R. P., Tetrahedron Lett., 1992, 33, 1495.
6. Khanna, M. S., Garg, C. P., and Kapoor, R. P., Synlett , 1992, 393.
7. Jacquier, R., Bull. Soc. Chim. Fr., 1950, 83.
8. Dalton, D. R., Dutta, V. P., and Jones, D. C., J. Am. Chem. Soc., 1968, 90, 5498.
9. 3 and subsequent acidic workup provided α-hydroxyketones in high yields, see Hoffman, R. V., Jankowski, B. C., and Carr, C. S. J. Org. Chem., 1986, 51, 130.