-
1
-
-
9044254525
-
P450 superfamily: Update on new sequences, gene mapping, accession numbers and nomenclature
-
D. R. Nelson, L. Koymans, T. Kamataki, J. J. Stegeman, R. Feyereisen, D. J. Waxman, M. R. Waterman, O. Gotoh, M. J. Coon, R. W. Estabrook, I. C. Gunsalus, and D. W. Nebert: P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature. Pharmacogenetics 6, 1-42 (1996).
-
(1996)
Pharmacogenetics
, vol.6
, pp. 1-42
-
-
Nelson, D.R.1
Koymans, L.2
Kamataki, T.3
Stegeman, J.J.4
Feyereisen, R.5
Waxman, D.J.6
Waterman, M.R.7
Gotoh, O.8
Coon, M.J.9
Estabrook, R.W.10
Gunsalus, I.C.11
Nebert, D.W.12
-
2
-
-
0018937071
-
Self-catalyzed inactivation of hepatic cytochrome P-450 by ethynyl substrates
-
P. R. Ortiz de Montellano, and K. L. Kunze: Self-catalyzed inactivation of hepatic cytochrome P-450 by ethynyl substrates. J. Biol. Chem. 255, 5578-5585 (1980).
-
(1980)
J. Biol. Chem.
, vol.255
, pp. 5578-5585
-
-
Ortiz De Montellano, P.R.1
Kunze, K.L.2
-
4
-
-
0024789979
-
2-Ethynylnaphthalene as a mechanism-based inactivator of the cytochrome P450 catalyzed N-oxidation of 2-naphthylamine
-
G. J. Hammons, W. L. Alworth, N. E. Hopkins, F. P. Guengerich, and F. F. Kadlubar: 2-Ethynylnaphthalene as a mechanism-based inactivator of the cytochrome P450 catalyzed N-oxidation of 2-naphthylamine. Chem. Res. Toxicol. 2, 367-374 (1989).
-
(1989)
Chem. Res. Toxicol.
, vol.2
, pp. 367-374
-
-
Hammons, G.J.1
Alworth, W.L.2
Hopkins, N.E.3
Guengerich, F.P.4
Kadlubar, F.F.5
-
5
-
-
0026468125
-
Modification of cytochrome P450 1A2 enzymes by the mechanism-based inactivator 2-ethynylnaphthalene and the photoaffinity label 4-azidobiphenyl
-
C. H. Yun, G. J. Hammons, G. Jones, M. V. Martin, N. E. Hopkins, W. L. Alworth, and F. P. Guengerich: Modification of cytochrome P450 1A2 enzymes by the mechanism-based inactivator 2-ethynylnaphthalene and the photoaffinity label 4-azidobiphenyl. Biochemistry 31, 10556-10563 (1992).
-
(1992)
Biochemistry
, vol.31
, pp. 10556-10563
-
-
Yun, C.H.1
Hammons, G.J.2
Jones, G.3
Martin, M.V.4
Hopkins, N.E.5
Alworth, W.L.6
Guengerich, F.P.7
-
6
-
-
0031021458
-
Aryl acetylenes as mechanism-based inhibitors of cytochrome P450-dependent monooxygenase enzymes
-
M. Foroozesh, G. Primrose, Z. Guo, L. C. Bell, W. L. Alworth, and F. P. Guengerich: Aryl acetylenes as mechanism-based inhibitors of cytochrome P450-dependent monooxygenase enzymes. Chem. Res. Toxicol. 10, 91-102 (1997).
-
(1997)
Chem. Res. Toxicol.
, vol.10
, pp. 91-102
-
-
Foroozesh, M.1
Primrose, G.2
Guo, Z.3
Bell, L.C.4
Alworth, W.L.5
Guengerich, F.P.6
-
7
-
-
0030598424
-
Mechanism-based inhibition of mouse P450 2b-10 by selected arylalkynes
-
L. E. Beebe, E. S. Roberts, L. W. Fornwald, P. F. Hollenberg, and W. L. Alworth: Mechanism-based inhibition of mouse P450 2b-10 by selected arylalkynes. Biochem. Pharmacol. 52, 1507-1513 (1996).
-
(1996)
Biochem. Pharmacol.
, vol.52
, pp. 1507-1513
-
-
Beebe, L.E.1
Roberts, E.S.2
Fornwald, L.W.3
Hollenberg, P.F.4
Alworth, W.L.5
-
9
-
-
0024790467
-
Metabolism of lidocaine by purified rat liver microsomal cytochrome P-450 isozymes
-
Y. Oda, S. Imaoka, Y. Nakahira, A. Asada, M. Fujimori, S. Fujita, and Y. Funae: Metabolism of lidocaine by purified rat liver microsomal cytochrome P-450 isozymes. Biochem. Pharmacol. 38, 4439-4444 (1989).
-
(1989)
Biochem. Pharmacol.
, vol.38
, pp. 4439-4444
-
-
Oda, Y.1
Imaoka, S.2
Nakahira, Y.3
Asada, A.4
Fujimori, M.5
Fujita, S.6
Funae, Y.7
-
10
-
-
0019523641
-
Purification to homogeneity and characterization of a form of cytochrome P450 with high specificity for benzo[a]pyrene from β-naphthoflavone-pretreated rat liver microsomes
-
T. Saito, and H. W. Strobel: Purification to homogeneity and characterization of a form of cytochrome P450 with high specificity for benzo[a]pyrene from β-naphthoflavone-pretreated rat liver microsomes. J. Biol. Chem. 256, 984-988 (1981).
-
(1981)
J. Biol. Chem.
, vol.256
, pp. 984-988
-
-
Saito, T.1
Strobel, H.W.2
-
11
-
-
0017795019
-
Purification and properties of NADPH-cytochrome P-450 reductase
-
H. W. Strobel, and J. D. Dignam: Purification and properties of NADPH-cytochrome P-450 reductase. Methods Enzymol. 52, 89-96 (1978).
-
(1978)
Methods Enzymol.
, vol.52
, pp. 89-96
-
-
Strobel, H.W.1
Dignam, J.D.2
-
12
-
-
0017833010
-
Two forms of liver microsomal cytochrome P450, P450 LM2 and P450 LM4 (rabbit liver)
-
M. J. Coon, T. A. van der Hoeven, S. B. Dahl, and D. A. Haugen: Two forms of liver microsomal cytochrome P450, P450 LM2 and P450 LM4 (rabbit liver). Methods Enzymol. 52, 109-117 (1978).
-
(1978)
Methods Enzymol.
, vol.52
, pp. 109-117
-
-
Coon, M.J.1
Van Der Hoeven, T.A.2
Dahl, S.B.3
Haugen, D.A.4
-
13
-
-
0023351645
-
Purification and characterization of the dog hepatic cytochrome P-450 isozyme responsible for the metabolism of 2,4,5,2′,4′,5′-hexachlorobiphenyl
-
D. B. Duignan, I. G. Sipes, T. B. Leonard, and J. R. Halpert: Purification and characterization of the dog hepatic cytochrome P-450 isozyme responsible for the metabolism of 2,4,5,2′,4′,5′-hexachlorobiphenyl. Arch. Biochem. Biophys. 255, 290-303 (1987).
-
(1987)
Arch. Biochem. Biophys.
, vol.255
, pp. 290-303
-
-
Duignan, D.B.1
Sipes, I.G.2
Leonard, T.B.3
Halpert, J.R.4
-
14
-
-
0028839554
-
Mechanism-based inactivation of cytochrome P450 2B1 by 9-ethynylphenanthrene
-
E. S. Roberts, N. E. Hopkins, E. J. Zaluzec, D. A. Gage, W. L. Alworth, and P. F. Hollenberg: Mechanism-based inactivation of cytochrome P450 2B1 by 9-ethynylphenanthrene. Arch. Biochem. Biophys. 323, 295-302 (1995).
-
(1995)
Arch. Biochem. Biophys.
, vol.323
, pp. 295-302
-
-
Roberts, E.S.1
Hopkins, N.E.2
Zaluzec, E.J.3
Gage, D.A.4
Alworth, W.L.5
Hollenberg, P.F.6
-
15
-
-
0027374515
-
A highly sensitive tool for the assay of cytochrome P450 enzyme activity in rat, dog, and man: Direct fluorescence of the deethylation of 7-ethoxy-4-trifluoromethylcoumarin
-
J. T. M. Buters, C. D. Schiller, and R. C. Chou: A highly sensitive tool for the assay of cytochrome P450 enzyme activity in rat, dog, and man: direct fluorescence of the deethylation of 7-ethoxy-4-trifluoromethylcoumarin. Biochem. Pharmacol. 46, 1577-1584 (1993).
-
(1993)
Biochem. Pharmacol.
, vol.46
, pp. 1577-1584
-
-
Buters, J.T.M.1
Schiller, C.D.2
Chou, R.C.3
-
16
-
-
0017847465
-
An improved assay of 7-ethoxycoumarin O-deethylase activity: Induction of hepatic enzyme activity in C57BL/6J and DBA/2J mice by phenobarbital, 3-methylcholanthrene, and 2,3,7,8-tetrachlorodibenzo-p-dioxin
-
W. F. Greenlee, and A. Poland: An improved assay of 7-ethoxycoumarin O-deethylase activity: induction of hepatic enzyme activity in C57BL/6J and DBA/2J mice by phenobarbital, 3-methylcholanthrene, and 2,3,7,8-tetrachlorodibenzo-p-dioxin. J. Pharmacol. Exp. Ther. 205, 596-605 (1978).
-
(1978)
J. Pharmacol. Exp. Ther.
, vol.205
, pp. 596-605
-
-
Greenlee, W.F.1
Poland, A.2
-
17
-
-
0021112308
-
19 steroids by 5 highly purified and reconstituted rat hepatic cytochrome P-450 isozymes
-
19 steroids by 5 highly purified and reconstituted rat hepatic cytochrome P-450 isozymes. J. Biol. Chem. 258, 8839-8847 (1983).
-
(1983)
J. Biol. Chem.
, vol.258
, pp. 8839-8847
-
-
Wood, A.W.1
Ryan, D.E.2
Thomas, P.E.3
Levin, W.4
-
18
-
-
0023654735
-
Regulation of testosterone hydroxylation by rat liver microsomal cytochrome P-450
-
A. J. Sonderfan, M. P. Arlotto, D. R. Dutton, S. K. McMillen, and A. Parkinson: Regulation of testosterone hydroxylation by rat liver microsomal cytochrome P-450. Arch. Biochem. Biophys. 255, 27-41 (1987).
-
(1987)
Arch. Biochem. Biophys.
, vol.255
, pp. 27-41
-
-
Sonderfan, A.J.1
Arlotto, M.P.2
Dutton, D.R.3
McMillen, S.K.4
Parkinson, A.5
-
19
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
U. K. Laemmli: Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (Lond.) 277, 680-685 (1970).
-
(1970)
Nature (Lond.)
, vol.277
, pp. 680-685
-
-
Laemmli, U.K.1
-
20
-
-
0028085833
-
Regio- and stereo-selective metabolism of phenanthrene by twelve cDNA-expressed human, rodent, and rabbit cytochromes P-450
-
M. Shou, K. R. Korzekwa, K. W. Krausz, C. L. Crespi, F. J. Gonzalez, and H. V. Gelboin: Regio-and stereo-selective metabolism of phenanthrene by twelve cDNA-expressed human, rodent, and rabbit cytochromes P-450. Cancer Lett. 83, 305-313 (1994).
-
(1994)
Cancer Lett.
, vol.83
, pp. 305-313
-
-
Shou, M.1
Korzekwa, K.R.2
Krausz, K.W.3
Crespi, C.L.4
Gonzalez, F.J.5
Gelboin, H.V.6
-
21
-
-
0022419376
-
Gene structure of a major form of phenobarbital-inducible cytochrome P-450 in rat liver
-
Y. Suwa, Y. Mizukami, K. Sogawa, and Y. Fujii-Kuriyama: Gene structure of a major form of phenobarbital-inducible cytochrome P-450 in rat liver. J. Biol. Chem. 260, 7980-7984 (1985).
-
(1985)
J. Biol. Chem.
, vol.260
, pp. 7980-7984
-
-
Suwa, Y.1
Mizukami, Y.2
Sogawa, K.3
Fujii-Kuriyama, Y.4
-
22
-
-
0012538590
-
Complete amino acid sequence and predicted membrane topology of phenobarbital-induced cytochrome P-450 (isozyme 2) from rabbit liver microsomes
-
G. E. Tarr, S. D. Black, V. S. Fujita, and M. J. Coon: Complete amino acid sequence and predicted membrane topology of phenobarbital-induced cytochrome P-450 (isozyme 2) from rabbit liver microsomes. Proc. Natl. Acad. Sci. USA 80, 6552-6556 (1983).
-
(1983)
Proc. Natl. Acad. Sci. USA
, vol.80
, pp. 6552-6556
-
-
Tarr, G.E.1
Black, S.D.2
Fujita, V.S.3
Coon, M.J.4
-
23
-
-
0024464027
-
cDNA cloning and sequence and cDNA-directed expression of human P450 HB1: Identification of a normal and two variant cDNAs derived from the CYP2B locus on chromosome 19 and differential expression of the IIB mRNAs in human liver
-
S. Yamano, P. T. Nhamburo, T. Aoyama, U. A. Meyer, T. Inaba, W. Kalow, H. V. Gelboin, O. W. McBride, and F. J. Gonzalez: cDNA cloning and sequence and cDNA-directed expression of human P450 HB1: identification of a normal and two variant cDNAs derived from the CYP2B locus on chromosome 19 and differential expression of the IIB mRNAs in human liver. Biochemistry 28, 7340-7348 (1989).
-
(1989)
Biochemistry
, vol.28
, pp. 7340-7348
-
-
Yamano, S.1
Nhamburo, P.T.2
Aoyama, T.3
Meyer, U.A.4
Inaba, T.5
Kalow, W.6
Gelboin, H.V.7
McBride, O.W.8
Gonzalez, F.J.9
-
24
-
-
0023766113
-
16α) of testosterone 16α-hydroxylase in mouse liver, chromosome localization, and cloning of P-450 cDNA
-
16α) of testosterone 16α-hydroxylase in mouse liver, chromosome localization, and cloning of P-450 cDNA. Biochemistry 27, 6434-6443 (1988).
-
(1988)
Biochemistry
, vol.27
, pp. 6434-6443
-
-
Noshiro, M.1
Lakso, M.2
Kawajiri, K.3
Negishi, M.4
-
25
-
-
0025341142
-
cDNA and deduced amino acid sequences of a dog hepatic cytochrome P450IIB responsible for the metabolism of 2,2′,4,4′,5,5′-hexachlorobiphenyl
-
P. E. Graves, G. A. Elhag, P. J. Ciaccio, D. P. Bourque, and J. R. Halpert: cDNA and deduced amino acid sequences of a dog hepatic cytochrome P450IIB responsible for the metabolism of 2,2′,4,4′,5,5′-hexachlorobiphenyl. Arch. Biochem. Biophys. 281, 106-115 (1990).
-
(1990)
Arch. Biochem. Biophys.
, vol.281
, pp. 106-115
-
-
Graves, P.E.1
Elhag, G.A.2
Ciaccio, P.J.3
Bourque, D.P.4
Halpert, J.R.5
-
26
-
-
0026569805
-
Cytochromes P-450 in rats: Structures, functions, properties and relevant human forms
-
P. Soucek, and I. Gut: Cytochromes P-450 in rats: structures, functions, properties and relevant human forms. Xenobiotica 22, 83-103 (1992).
-
(1992)
Xenobiotica
, vol.22
, pp. 83-103
-
-
Soucek, P.1
Gut, I.2
-
27
-
-
0026542174
-
Topological analysis of the active sites of cytochromes P450IIB4 (rabbit), P450 IIB10 (mouse), and P450 IIB11 (dog) by in situ rearrangement of phenyl-iron complexes
-
B. A. Swanson, J. R. Halpert, L. M. Bornheim, and P. R. Ortiz de Montellano: Topological analysis of the active sites of cytochromes P450IIB4 (rabbit), P450 IIB10 (mouse), and P450 IIB11 (dog) by in situ rearrangement of phenyl-iron complexes. Arch. Biochem. Biophys. 292, 42-46 (1992).
-
(1992)
Arch. Biochem. Biophys.
, vol.292
, pp. 42-46
-
-
Swanson, B.A.1
Halpert, J.R.2
Bornheim, L.M.3
Ortiz De Montellano, P.R.4
-
28
-
-
0025988888
-
The active sites of cytochromes P450 1A1, IIB1, IIB2, and IIE1
-
B. A. Swanson, D. R. Dutton, J. M. Lunetta, C. S. Yang, and P. R. Ortiz de Montellano: The active sites of cytochromes P450 1A1, IIB1, IIB2, and IIE1. J. Biol. Chem. 266, 19258-19264 (1991).
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 19258-19264
-
-
Swanson, B.A.1
Dutton, D.R.2
Lunetta, J.M.3
Yang, C.S.4
Ortiz De Montellano, P.R.5
-
29
-
-
0028858960
-
Cytochrome P450 inhibitors: Evaluation of specificities in the in vitro metabolism of therapeutic agents by human liver microsomes
-
D. J. Newton, R. W. Wang, and A. Y. Lu: Cytochrome P450 inhibitors: evaluation of specificities in the in vitro metabolism of therapeutic agents by human liver microsomes. Drug Metab. Dispos. 23, 154-158 (1995).
-
(1995)
Drug Metab. Dispos.
, vol.23
, pp. 154-158
-
-
Newton, D.J.1
Wang, R.W.2
Lu, A.Y.3
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